Abstracts tagged "radiography"

Abstract Number: 0160 • ACR Convergence 2021
Identifying Erosive Disease from Radiology Reports of Veterans with Inflammatory Arthritis with Natural Language Processing
Gopi Penmetsa¹, Jessica Walsh², Shaobo Pei³, Brian Sauer⁴, Kevin Douglas⁵, Jodi Walker⁵, Jerry Clewell⁶ and Bingjian Feng¹, ¹Salt Lake City Veteran Affairs and University of Utah Medical Centers, Salt Lake City, UT, ²Salt Lake City Veteran Affairs Medical Center (VAMC)/University of Utah Hospital, Salt Lake City, UT, ³VAMC, Salt Lake City, SLC, ⁴Veterans Affairs Medical Center, Salt Lake City, UT, ⁵AbbVie Inc., North Chicago, IL, ⁶Abbvie Inc, North Chicago, IL
Background/Purpose: The presence of erosive disease influences diagnosis, management, & prognosis in inflammatory arthritis (IA). Inflammatory arthritis research in large datasets is limited by a…
Abstract Number: 0168 • ACR Convergence 2021
A Crowdsourcing Approach to Develop Machine Learning Models to Quantify Radiographic Joint Damage in Rheumatoid Arthritis
Dongmei Sun¹, Robert Allaway², Jelai Wang¹, Verena Chung², Thomas Yu², Isaac Dimitrovsky³, Lars Ericson⁴, Yuanfang Guan⁵, Ariel Israel⁶, Hongyang Li⁵, Michael Mason⁷, Alex Olar⁸, Balint Pataki⁸, Stephanie Ledbetter¹, RA2 DREAM Challenge Community⁹, Gustavo Stolovitzky¹⁰, Justin Guinney², Percio Gulko¹¹, Mason Frazier¹, James Costello¹², Jake Chen¹ and S. Louis Bridges, Jr.¹³, ¹University of Alabama at Birmingham, Birmingham, AL, ²Sage Bionetworks, Seattle, WA, ³Self-employed, New York, NY, ⁴Catskills Research, Charlotte, NC, ⁵University of Michigan, Ann Arbor, MI, ⁶Hebrew University, Jerusalem, Israel, ⁷BMS, Seattle, WA, ⁸Eotvos Lorand University, Budapest, Hungary, ⁹RA2 DREAM Challenge Community, New York, NY, ¹⁰IBM, New York, NY, ¹¹Icahn School of Medicine at Mount Sinai, New York, NY, ¹²University of Colorado Anschutz Medical Campus, Denver, CO, ¹³Hospital for Special Surgery, New York, NY
Background/Purpose: Rheumatoid arthritis (RA) is a common chronic autoimmune disease characterized by inflammation of the synovium, leading to joint space narrowing and osseous erosions. The…
Abstract Number: 0182 • ACR Convergence 2021
Tenderness and Radiographic Progression in Rheumatoid Arthritis and Psoriatic Arthritis
Irina Gessl¹, Mihaela Popescu², Gabriela Supp¹, Martina Durechova¹, Michael Zauner¹, Josef Smolen¹, Daniel Aletaha³ and Peter Mandl¹, ¹Medical University of Vienna, Vienna, Austria, ²Maisonneuve Rosemont Hospital, Longueuil, QC, Canada, ³Medical University Vienna, Vienna, Austria
Background/Purpose: In rheumatoid arthritis (RA) and psoriatic arthritis (PsA), swelling is regarded as a sign of synovitis and is associated with radiographic progression. However, recent…
Abstract Number: 0211 • ACR Convergence 2021
Unsupervised Machine-learning Algorithms for the Identification of Clinical Phenotypes in the Osteoarthritis Initiative Database
David Demanse¹, László B. Tankó², Patrick Lustenberger³, Philipp Nikolaus³, Ilja Rasin³, Damian F. Brennan³, Franziska Saxer², Ronenn Roubenoff⁴, Sumehra Premji¹, Philip Conaghan⁵ and Matthias Schieker⁴, ¹Novartis Pharma AG, Basel, Switzerland, ²Novartis Institutes for Biomedical Research, Basel, Switzerland, ³IBM Switzerland AG, Zürich, Switzerland, ⁴Novartis Institutes for Biomedical Research, Basel, Switzerland, Basel, Switzerland, ⁵Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom
Background/Purpose: Osteoarthritis (OA) is a chronic disabling disease, for which there are only limited treatment options. One major challenge in the development of effective treatment…
Abstract Number: 0214 • ACR Convergence 2021
Baseline Cam or Pincer Morphology Is Associated with Loss of Quantitative Joint Space Width at the Hip: The Johnston County Osteoarthritis Project
Amanda Nelson¹, Carolina Alvarez¹, Yvonne Golightly¹, Jamie Stiller², Jordan Renner¹, Nigel Arden³, Charles Ratzlaff⁴ and Jeffrey Duryea⁵, ¹University of North Carolina at Chapel Hill, Chapel Hill, NC, ²Alamance Regional Medical Center, Durham, NC, ³University of Oxford, Oxford, United Kingdom, ⁴University of British Columbia, Vancouver, BC, Canada, ⁵Brigham and Women's Hospital, Boston, MA
Background/Purpose: To determine the association between radiographic cam and pincer morphology and loss of hip quantitative joint space width (qJSW) in a community-based cohort.Methods: Data…
Abstract Number: 0215 • ACR Convergence 2021
Ultrasonographic Assessment of Knee Osteoarthritis and Its Agreement with Radiography
Khoa Nguyen¹ and Duc Tran², ¹Deparment of Rheumatology, Cho Ray Hospital, Ho Chi Minh City, Vietnam, ²Department of Rheumatology, Cho Ray Hospital, Ho Chi Minh, Vietnam
Background/Purpose: Ultrasonography (US) has been increasingly utilized for the assessment of various musculoskeletal conditions. However, the value of this tool in diagnosis of osteoarthritis (OA)…
Abstract Number: 0218 • ACR Convergence 2021
Synovitis Does Not Mediate the Relationship Between Body Mass Index and Progression of Radiographic Knee Osteoarthritis: Data from the Osteoarthritis Initiative
Marina Bañuls¹, Alecio Lombardi¹, Eric Chang¹, Aladdin H Shadyab¹, Nancy Lane² and Monica Guma³, ¹University of California San Diego, San Diego, CA, ²University of California Davis, Hillsborough, CA, ³University of California San Diego, La Jolla, CA
Background/Purpose: Synovial inflammation is associated with knee osteoarthritis (KOA) progression. Body mass index (BMI) has also been associated with KOA progression. Yet, it is unclear…
Abstract Number: 0451 • ACR Convergence 2021
Tumor Necrosis Factor Inhibitors Show a Delayed Effect on Radiographic Sacroiliitis Progression in Patients with Early Axial Spondyloarthritis: 10-Year Results from the German Spondyloarthritis Inception Cohort
Murat Torgutalp¹, Valeria Rios Rodriguez¹, Maryna Verba², Mikhail Protopopov¹, Fabian Proft¹, Judith Rademacher¹, Hildrun Haibel³, Martin Rudwaleit⁴, Joachim Sieper³ and Denis Poddubnyy⁵, ¹Charité University Medicine Berlin, Berlin, Germany, ²Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin Department of Gastroenterology, Infectiology and Rheumatology (including Nutrition Medicine), Berlin, Germany, ³Department of Gastroenterology, Infectiology and Rheumatology (including Nutrition Medicine), Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany, ⁴University of Bielefeld, Klinikum Bielefeld, Bielefeld, Germany, ⁵Department of Rheumatology, Charité – Universitätsmedizin, Berlin, Germany
Background/Purpose: Observational cohort studies have shown that there is low, but still detectable progression level in radiographic sacroiliitis, which might also have an impact on…
Abstract Number: 0479 • ACR Convergence 2021
A Novel Semi-automated Classifier of Radiographic Hip Osteoarthritis on DXA Scans Is Strongly Predictive of Pain, Clinical Diagnosis and Joint Replacement: Findings from 40,000 Participants in UK Biobank
Benjamin Faber¹, Raja Ebsim², Fiona Saunders³, Monika Frysz¹, Claudia Lindner², Jennifer Gregory³, Richard Aspden³, Nicholas Harvey⁴, George Davey Smith¹, Timothy Cootes² and Jon Tobias¹, ¹University of Bristol, Bristol, United Kingdom, ²University of Manchester, Manchester, United Kingdom, ³University of Aberdeen, Aberdeen, United Kingdom, ⁴University of Southampton, Southampton, United Kingdom
Background/Purpose: Radiographic hip osteoarthritis (rHOA) is traditionally defined on hip or pelvic radiographs, using subjective methods such as Kellgren-Lawrence scoring. Associations between subjective rHOA measures…
Abstract Number: 0897 • ACR Convergence 2021
Age-Stratified Trend of Spinal Radiographic Damage Progression in Patients with Ankylosing Spondylitis
Tae-Han Lee¹, Bon San Koo², Bora Nam³, Seunghun Lee⁴, Kyung Bin Joo⁴ and Tae-Hwan Kim³, ¹Keimyung University Dongsan Hospital, Daegu, Republic of Korea, ²Inje University Seoul Paik Hospital, Seoul, Republic of Korea, ³Hanyang University Hospital for Rheumatic Diseases, Seoul, Republic of Korea, ⁴Hanyang University Hospital, Seoul, Republic of Korea
Background/Purpose: Previous studies investigating the course of spinal structural progression in patients with ankylosing spondylitis (AS) using the modified Stoke Ankylosing Spondylitis Spine Score (mSASSS)…
Abstract Number: 1756 • ACR Convergence 2020
Comparable Long-Term Outcomes Among DAS28-ESR-based Remission Criteria and ACR/EULAR Definitions in Patients with Established Rheumatoid Arthritis
Felipe Julio Ramirez Garcia¹, Jose Inciarte-Mundo², Andrea Cuervo³, Raquel Celis⁴, Virginia Ruiz-Esquide⁴, Raul Castellanos-Moreira⁵, Andres Ponce⁴, Jose Gómez-Puerta⁶, Raimon Sanmartí⁶ and Juan Cañete⁷, ¹Arthritis Unit, Rheumatology Dpt, Hospital Clinic, Barcelona, Spain, Barcelona, Catalonia, Spain, ²Hospital Universitari Clínic de Barcelona, Barcelona, ³Hospital Clínic, Barcelona, Spain, ⁴Hospital Clinic, Barcelona, Spain, ⁵Hospital Clinic of Barcelona, Barcelona, Spain, ⁶Hospital Universitari Clínic de Barcelona, Barcelona, Catalonia, Spain, ⁷Arthritis Unit, Rheumatology Dpt, Hospital Clinic, Barcelona, Spain and IDIBAPS, Barcelona, Spain
Background/Purpose: To compare long-term clinical and radiographic outcomes among five sets of remission criteria [four clinical and one Ultrasound (US)-based] in a cohort of RA…
Abstract Number: 1895 • ACR Convergence 2020
Radiographic Progression in Patients with Axial Spondyloarthritis Under Treatment with TNF Inhibitors. Data from REGISPONSERBIO (Spanish Register of Biological Therapy in Spondyloarthritides)
Maria Llop¹, Mireia Moreno², Jordi Gratacós³, Victoria Navarro-Compán⁴, Eugenio De Miguel⁵, Pilar Font⁶, Teresa Clavaguera⁷, Luis Francisco Linares⁸, Beatriz Joven⁹ and Xavier Juanola¹⁰, ¹Hospital Universitari Parc Taulí I3PT, Sabadell, Catalonia, Spain, ²Hospital Universitari Parc Taulí I3PT, Sabadell, Spain, ³University Hospital Parc Tauli Sabadell, Barcelona, Spain, ⁴Hospital Universitario La Paz IdiPaz, Madrid, Pais Vasco, Spain, ⁵Rheumatology Department, Hospital Universitario La Paz, Madrid, Spain, ⁶Rheumatology Department, Reina Sofia University Hospital/ Maimonides Institute for Research in Biomedicine of Cordoba (IMIBIC)/ University of Cordoba, Cordoba, Spain, Córdoba, Spain, ⁷Hospital Universitari Trueta, Girona, Spain, ⁸Hospital de la Arrixaca, Murcia, ⁹Hospital Universitario 12 de Octubre, Madrid, Spain, ¹⁰Rheumatology Service, University Hospital Bellvitge, IDIBELL, Barcelona, Spain, Barcelona, Spain
Background/Purpose: Clinical efficacy of TNF inhibitors (TNFi) in axial spondyloarthritis (axSpA) has been widely probed in randomized control trials. In clinical practice, some studies suggested…
Abstract Number: 1975 • ACR Convergence 2020
Predicting Bone Mineral Density of Lumbar Vertebrae by Assessing Plain Film with Deep Learning
Chen-I Hsieh¹, Chang-Fu Kuo¹, Shun Miao², Kang Zheng² and Le Lu², ¹Chang Gung Memorial Hospital, Taoyuan, Taiwan (Republic of China), ²PAII labs, Bethesda, MD
Background/Purpose: Osteoporosis is a silent disease characterized by a decrease in bone mineral density (BMD), causing bone fragility and increased risk of fracture. The most…
Abstract Number: 2016 • ACR Convergence 2020
Baseline Serum Biomarker Levels Predict Spinal Radiographic Progression in Ankylosing Spondylitis Patients on TNF Inhibitor Therapy
Judith Rademacher¹, Mark Siderius², Laura Gellert¹, Freke Wink³, Maryna Verba¹, Fiona Maas⁴, Lorraine M Tietz¹, Denis Poddubnyy⁵, Anneke Spoorenberg³ and Suzanne Arends³, ¹Charité Universitätsmedizin Berlin, Berlin, Germany, ²Department of Rheumatology and Clinical Immunology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands, ³University Medical Centre Groningen and Medical centre Leeuwarden, Groningen, Netherlands, ⁴University medical Centre Groningen, Groningen, Netherlands, ⁵Charité – Universitätsmedizin Berlin, Berlin, Germany
Background/Purpose: Radiographic spinal progression determinates functional status and mobility in ankylosing spondylitis (AS) (Poddubnyy et al, 2018). Our objective was to analyze whether biomarker levels…
Abstract Number: 2017 • ACR Convergence 2020
Machine Learning Identifies an Association Between Pre-existing Radiographic Damage and Long-term Clinical Outcomes with Secukinumab Therapy in Patients with Psoriatic Arthritis
Philip Mease¹, Désirée van der Heijde², Bruce Kirkham³, Georg Schett⁴, Ana-Maria Orbai⁵, Christopher Ritchlin⁶, Joseph Merola⁷, Luminita Pricop⁸, Xuan Zhu⁹, DavidA James⁹ and Gregory Ligozio⁹, ¹Seattle Rheumatology Associates, P.L.L.C., Seattle, WA, ²Leiden University Medical Center, Leiden, Netherlands, ³Guy's & St Thomas' NHS Foundation Trust, London, United Kingdom, ⁴Friedrich-Alexander-Universität Erlangen- Nuremberg, Erlangen, Germany, ⁵Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, ⁶Department of Medicine, University of Rochester Medical Center, Rochester, NY, ⁷Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, ⁸Novartis Pharmaceuticals Corporation, East Hanover, ⁹Novartis Pharmaceuticals Corporation, East Hanover, NJ
Background/Purpose: Assessment of radiographic joint damage extent and progression is important in clinical trials evaluating treatments for psoriatic arthritis (PsA). Joint damage in patients with…

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