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Abstracts tagged "quality of life"

  • Abstract Number: 1332 • ACR Convergence 2021

    Validation of the PROMIS-29 Profile in Patients with Active Psoriatic Arthritis Using Data from a Phase 3, Randomized, Placebo-Controlled Study Evaluating Guselkumab (TREMFYA®)

    Ana-Maria Orbai1, Laura Coates2, Atul Deodhar3, Christopher Ritchlin4, Alexa Kollmeier5, Marlies Neuhold6, Yi-Hsuan Liu7, Yan Liu7 and Chenglong Han7, 1Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, 2Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom, 3Oregon Health & Science University, Portland, OR, 4Division of Allergy, Immunology, and Rheumatology, School of Medicine and Dentistry, University of Rochester Medical Center, Rochester, NY, 5Janssen Research & Development, LLC, La Jolla, CA, 6Janssen-Cilag, Zug, Switzerland, 7Janssen Research & Development, LLC, Spring House, PA

    Background/Purpose: It is important to assess symptoms of pain, fatigue, anxiety, depression, sleep disturbance, and impaired physical function in patients (pts) with psoriatic arthritis (PsA),…
  • Abstract Number: 1894 • ACR Convergence 2021

    Natural Language Processing Tool for Extraction of Patient-Reported Outcomes from a National Multi-Electronic Health Records Registry

    Marie Humbert-Droz1, Zara Izadi2, Gabriela Schmajuk2, Milena Gianfrancesco2, Jinoos Yazdany2 and Suzanne Tamang3, 1Stanford University, Stanford, 2University of California San Francisco, San Francisco, CA, 3Stanford Center for Population Health Sciences, Redwood City, CA

    Background/Purpose: Patient reported outcomes (PROs) are increasingly used to track disease activity and facilitate shared decision making in patients with RA. Assessments of disease activity…
  • Abstract Number: 0314 • ACR Convergence 2021

    PROMIS Provides a Broad Overview of Health-Related Quality of Life in the Evaluation of Sjogren’s Syndrome

    Dana DiRenzo1, Susan Robinson2, Clifton Bingham1, Alan Baer3 and Thomas Grader-Beck1, 1Johns Hopkins University, Baltimore, MD, 2Johns Hopkins, Baltimore, MD, 3Johns Hopkins University School of Medicine, Baltimore, MD

    Background/Purpose: Sjogren’s Syndrome (SS) is a systemic autoimmune disease that has considerable impact on health-related quality of life (HRQL). The European League Against Rheumatism (EULAR)…
  • Abstract Number: 0798 • ACR Convergence 2021

    The Impact of Comorbidities on the Simple Disease Activity Index (SDAI) and Its Components over the First Year of Follow-up – an Analysis from the Canadian Early Arthritis Cohort (CATCH)

    Lillian-Ruiheng Chen1, Orit Schieir2, Marie-France Valois3, Janet Pope4, Susan Bartlett3, Gilles Boire5, Glen Hazlewood6, Carol Hitchon7, Edward C. Keystone8, Diane Tin9, Carter Thorne10, Narcisse Singbo1, Vivian Bykerk11 and Louis Bessette12, 1Centre de recherche du CHU de Québec-Université Laval, Québec City, QC, Canada, 2Canadian Early Arthritis Cohort Study, Montréal, QC, Canada, 3McGill University, Montréal, QC, Canada, 4University of Western Ontario, London, ON, Canada, 5Universite de Sherbrooke, Sherbrooke, QC, Canada, 6University of Calgary, Calgary, AB, Canada, 7University of Manitoba, Winnipeg, MB, Canada, 8Mount Sinai Hospital, Toronto, ON, Canada, 9The Arthritis Program Research Group, Newmarket, ON, Canada, 10Southlake Regional Health Centre, Newmarket, ON, Canada, 11Hospital for Special Surgery, New York, NY, 12Centre de l'Ostoporose et de Rhumatologie de Qubec, Québec City, QC, Canada

    Background/Purpose: Comorbid conditions have been shown to negatively influence the achievement of treatment targets in rheumatoid arthritis (RA) patients. The comorbid conditions may bias the…
  • Abstract Number: 1344 • ACR Convergence 2021

    Impact of Achieving Minimal Disease Activity on Patient-Reported Outcome Measures and Disease Activity Among Patients with Psoriatic Arthritis Treated with Biologic and Targeted Synthetic DMARDs

    Alexis Ogdie1, Robert McLean2, Maya Marchese2, Taylor Blachley2, Laura Anatale-Tardiff3, Christopher Saffore4, Kevin Douglas5, Danny Quach5 and Philip Mease6, 1University of Pennsylvania, Philadelphia, PA, 2CorEvitas, LLC, Waltham, MA, 3CorEvitas, Waltham, MA, 4AbbVie, North Chicago, IL, 5AbbVie Inc., North Chicago, IL, 6Swedish Medical Center/Providence St. Joseph Health and University of Washington, Seattle, WA

    Background/Purpose: Minimal disease activity (MDA) is a common goal for disease control when managing PsA. The aim of this study was to assess the association…
  • Abstract Number: 1910 • ACR Convergence 2021

    Association Between Clinically Meaningful Improvements in Patient-Reported Outcomes and Stringent Measures of Disease Activity in Patients with Psoriatic Arthritis Treated with Upadacitinib versus Placebo or Adalimumab: Results from a Phase 3 Trial

    Laure Gossec1, Nemanja Damjanov2, Shigeyoshi Tsuji3, Apinya Lertratanakul4, Ralph Lippe5, Jayeshkumar Patel4, Patrick Zueger6 and Kurt de Vlam7, 1Sorbonne Université; APHP, Rheumatology Department, Pitié-Salpêtrière Hospital, Paris, France, 2University of Belgrade School of Medicine, Institute of Rheumatology, Belgrade, Serbia, 3Department of Orthopaedics/Rheumatology, National Hospital Organization, Osaka Minami Medical Center, Osaka, Japan, 4AbbVie Inc., North Chicago, IL, 5AbbVie Deutschland GmbH & Co. KG, Berlin, Germany, 6AbbVie Inc., Mettawa, IL, 7Department of Rheumatology, Universitaire Ziekenhuizen Leuven, Leuven, Belgium

    Background/Purpose: The achievement of disease control has been shown to be associated with improved prognosis in PsA, though no single measure of low disease activity…
  • Abstract Number: 0168 • ACR Convergence 2020

    Impact of Adalimumab (Humira) Therapy on Ocular Inflammation, Selected Health Care Resource Utilization, and Patient-Reported Outcomes in Patients with Active Non-infectious Intermediate, Posterior, or Panuveitis in Routine Clinical Practice

    Uwe Pleyer1, Salem Almutairi2, Conor Murphy3, Rola Hamam4, Karina Julian5, Shereen Hammad6, Orsolya Nagy7, Zohar Habot-Wilner8, Zsuzsanna Szepessy9, Yan Guex-Crosier10 and Sofia Androudi11, 1Charité Universitätsmedizin Berlin, Klinik für Augenheilkunde, Berlin, Germany, 2Al-Bahar Ophthalmology Center - Al-Sabah Hospital, Kuwait City, Kuwait, 3Royal Victoria Eye & Ear Hospital, Dublin, Ireland, 4American University of Beirut, Beirut, Lebanon, 5Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates, 6AbbVie Biopharmaceuticals GmbH, Dubai, United Arab Emirates, 7AbbVie Kft, Budapest, Hungary, 8Tel Aviv Sourasky Medical Center, Tel Aviv University, Tel Aviv, Israel, 9Semmelweis University, Budapest, Hungary, 10Jules-Gonin Eye Hospital, Department of Ophthalmology, University of Lausanne, Lausanne, Switzerland, 11University of Thessaly, Larissa, Greece

    Background/Purpose: VISUAL clinical trials demonstrated efficacy and safety of adalimumab (ADA) in patients with active and inactive non-infectious, intermediate, posterior, or panuveitis (NIIPPU).1-3 The purpose…
  • Abstract Number: 0930 • ACR Convergence 2020

    Sexual Health Impairment in 90 Female Patients with Systemic Sclerosis

    Barbora Hermankova1, Maja Spiritovic2, Sabina Oreska3, Hana Storkanova4, Hana Smucrova5, Karel Pavelka6, Jiří Vencovský6, Ladislav Šenolt6, Radim Becvar4 and Michal Tomcik4, 1Faculty of Physical Education and Sport, Charles University, Prague, Czech Republic, Prague, Hlavni mesto Praha, Czech Republic, 2Faculty of Physical Education and Sport, Charles University, Prague, Czech Republic, Prague, Czech Republic, 3Institute of Rheumatology, Prague, Czech Republic. Department of Rheumatology, 1st Faculty of Medicine, Charles University, Prague, Czech Republic, Praha 2, Czech Republic, 4Institute of Rheumatology, Prague, Czech Republic. Department of Rheumatology, 1st Faculty of Medicine, Charles University, Prague, Czech Republic, Prague, Czech Republic, 5Institute of Rheumatology, Prague, Czech Republic, Prague, Czech Republic, 6Institute of Rheumatology and Department of Rheumatology, First Faculty of Medicine, Charles University, Prague, Czech Republic

    Background/Purpose: Systemic sclerosis (SSc) is a chronic, multisystem, connective tissue disorder characterized by fibrosis of the skin and internal organ involvement. These serious clinical manifestations…
  • Abstract Number: 1341 • ACR Convergence 2020

    Improvement in Patient-Reported Outcomes in Patients with Psoriatic Arthritis with Inadequate Response to Non-Biologic DMARDs Treated with Upadacitinib versus Placebo or Adalimumab: Results from a Phase 3 Study

    Vibeke Strand1, Philip Mease2, Enrique Soriano3, Mitsumasa Kishimoto4, Carlo Salvarani5, Nemanja Damjanov6, Jaclyn K Anderson7, Erin Blondell7, Patrick Zueger7, Christopher Saffore7 and Dafna Gladman8, 1Division of Immunology/Rheumatology, Stanford University, Palo Alto, CA, 2Seattle Rheumatology Associates, P.L.L.C., Seattle, WA, 3Department of Public Health, Instituto Universitario, Escuela de Medicina Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Rheumatology Unit, Internal Medicine Services, Hospital Italiano de Buenos Aires, Capital Federal, Buenos Aires, Argentina, 4Department of Nephrology and Rheumatology, Kyorin University School of Medicine, Yokohama, Japan, 5Rheumatology Units, University of Modena and Reggio Emilia, and Azienda USL-IRCCS di Reggio Emilia, REGGIO EMILIA, Italy, 6University of Belgrade Medical School, Belgrade, Serbia, 7AbbVie Inc., North Chicago, IL, 8Krembil Research Institute, Toronto Western Hospital, Toronto, ON, Canada

    Background/Purpose: Patient-reported outcomes (PROs) are important when evaluating treatment benefits in PsA. We present an analysis of PRO data from the SELECT-PsA 1 study.Methods: SELECT-PsA…
  • Abstract Number: 0198 • ACR Convergence 2020

    A Prospective Cohort Study of Vehicle Control as a Measure of Driving Performance in Patients with Rheumatoid Arthritis

    Kaleb Michaud1, Jennifer Merickel1, Yeongjin Gwon1, Harlan Sayles1, Haley Kampschnieder1, Rebecca Hiebert1, Alison Petro1, Bryant England1, Matthew Rizzo1 and Ted Mikuls1, 1University of Nebraska Medical Center, Omaha, NE

    Background/Purpose: Automobile driving is an instrumental activity of daily living. Owing to symptoms and functional impairment, patients with rheumatoid arthritis (RA) rely disproportionately on driving…
  • Abstract Number: 1011 • ACR Convergence 2020

    Effectiveness, Safety and Quality of Life with Tofacitinib Treatment in Adult Patients with Rheumatoid Arthritis Under Routine Clinical Care: First Interim Results from a German Non-Interventional, Prospective, Multi-Center Study

    Frank Behrens1, Ulrich Prothmann2, Thilo Klopsch3, Ann-Dörthe Holst4, Lisa Blindzellner5, Olaf Behmer5, Pascal Klaus5, Thomas Meng5 and Peter-Andreas Löschmann5, 1CIRI/Rheumatology & Fraunhofer IME, Research Division Translational Medicine and Pharmacology, Goethe University Hospital, Frankfurt, Hessen, Germany, 2Knappschaftsklinikum Saar, Püttlingen, Saarland, Germany, 3Rheumatological Practice, Neubrandenburg, Mecklenburg-Vorpommern, Germany, 4Specialist Practice for General Medicine incl. Rheumatology and Acupuncture, Ludwigslust, Mecklenburg-Vorpommern, Germany, 5Pfizer Pharma GmbH, Berlin, Berlin, Germany

    Background/Purpose: Tofacitinib is an orally applied Janus kinase inhibitor, which is approved for rheumatoid arthritis (RA) treatment in the USA since 2012, so that ‘real…
  • Abstract Number: 1371 • ACR Convergence 2020

    Improvement in Patient-Reported Outcomes for Upadacitinib versus Placebo Among Patients with Psoriatic Arthritis and an Inadequate Response to Biologic Disease-Modifying Anti-Rheumatic Drugs

    Vibeke Strand1, Filip Van den Bosch2, Roberto Ranza3, Ying Ying Leung4, Edit Drescher5, Apinya Lertratanakul6, Ralph Lippe7, Christopher Saffore6, Patrick Zueger6 and Peter Nash8, 1Division of Immunology/Rheumatology, Stanford University, Palo Alto, CA, 2Ghent University Hospital, Ghent, Belgium, 3Hospital de Clinicas, Universidade Federal de Uberlândia, Uberlândia, Brazil, 4Department of Rheumatology & Immunology, Singapore General Hospital, Singapore, Singapore, 5Veszprém Csolnoky Ferenc County Hospital, Veszprém, Hungary, 6AbbVie Inc., North Chicago, IL, 7AbbVie Deutschland GmbH & Co. KG, Wiesbaden, Germany, 8School of Medicine Griffith University, Brisbane, Queensland, Australia

    Background/Purpose: The efficacy and safety of upadacitinib (UPA), a selective Janus kinase inhibitor, in patients with PsA is under investigation in Phase 3 clinical trials.…
  • Abstract Number: 0249 • ACR Convergence 2020

    Validation of the SIMPLE Index for Disease Activity of Systemic Lupus Erythematosus in Chinese Patients

    Chi Chiu Mok1, Ling Yin Ho1, Kar Li Chan2 and Meenakshi Jolly3, 1Tuen Mun Hospital, Hong Kong, China (People's Republic), 2Tuen Mun Hospital, Hong Kong, Hong Kong, 3Rush University, Chicago, IL

    Background/Purpose: The SIMPLE (SIMple Disease Assessment for People with Lupus Erythematosus) index is a composite numeric tool that captures disease activity from patients’ self-assessment with…
  • Abstract Number: 1020 • ACR Convergence 2020

    Relationship Between Skin-related Quality of Life, Psychosocial Stress, and Race in Cutaneous Lupus Erythematosus

    Cristina Drenkard1, Laura Aspey1, Gaobin Bao1, Caroline Gordon2, Kristina Theis3, Charles Helmick3 and S. Sam Lim1, 1Emory University, Atlanta, GA, 2University of Birmingham, Birmingham, England, United Kingdom, 3Centers for Disease Control and Prevention, Atlanta, GA

    Background/Purpose: Chronic stress may trigger or exacerbate physiologic pathways that worsen individual health and wellbeing. Stress is associated with the development and progression of skin…
  • Abstract Number: 1397 • ACR Convergence 2020

    Clinical and Demographic Features of Morphea Patients with Mucocutaneous Involvement: A Cross Sectional Study from the Morphea of Adults and Children Cohort

    Smriti Prasad1, Samantha Black2, Shivani Sharma3 and Heidi Jacobe1, 1University of Texas Southwestern Medical Center, Dallas, TX, 2The University of Texas Southwestern Medical Center, Dallas, TX, 3University of Texas Southwestern, Dallas, TX

    Background/Purpose: Morphea is an autoimmune skin condition that produces skin and soft tissue sclerosis. While clinical manifestations of morphea have been well-described, mucocutaneous findings such…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM CT on October 25. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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