ACR Meeting Abstracts

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Abstracts tagged "pulmonary"

  • Abstract Number: 2522 • ACR Convergence 2024

    Anticoagulant Treatment May Decrease the Relapse Rate in Pulmonary Arterial Involvement of Behçet’s Disease When Added After the First Event

    Kerem Abacar1, Ayşe Elif Boncukcuoğlu1, Aysun Aksoy2, Derya Kocakaya1, Çagatay Cimşit1, Haner Direskeneli3 and Fatma Alibaz Öner3, 1Marmara University, istanbul, Turkey, 2Alaaddin Keykubat University, Antalya, Turkey, 3Marmara University Faculty of Medicine, Rheumatology, İstanbul, Turkey, Istanbul, Turkey

    Background/Purpose: Vascular inflammation in Behcet’s Disease (BD) is one of the most important causes of mortality due to pulmonary artery involvement (PAI) or Budd-Chiari syndrome.…
  • Abstract Number: 0714 • ACR Convergence 2024

    Therapeutic Dilemmas in Patients with ANCA-associated Vasculitis: Diffuse Alveolar Hemorrhage, Venous Thromboembolism and Anticoagulation

    Elif Ediboglu1, Samuel Falde1, Misbah Baqir1, Rodrigo Cartin-Ceba2, Robert McBane1 and Ulrich Specks1, 1Mayo Clinic, Rochester, MN, 2Mayo Clinic, Scottsdale, AZ

    Background/Purpose: Diffuse alveolar hemorrhage (DAH) is an acutely life-threating presentation of ANCA-associated vasculitis (AAV), and patients with AAV are at increased risk of venous thromboembolic…
  • Abstract Number: 1595 • ACR Convergence 2024

    Tezepelumab for Relapsing or Refractory Eosinophilic Granulomatosis with Polyangiitis: A European Retrospective Study

    Margot Poux1, Matthieu Groh2, Alexandra Nanzerkelly3, Marco Caminati4, candice Lacroix5, stephanie Habib6 and Benjamin Terrier7, 1Université de Paris cité, PARIS 04EME, France, 2Foch, Suresnes, France, 3King's college London, London, 4Department of Medicine, Asthma, Allergy and Clinical Immunology Section, University of Verona, Verona, Italy, 5Université de Paris cité, Paris, 6Service de Pneumologie, Hôpital Cochin, APHP Centre et Université Paris Cité, Paris, France, 7Service de Médecine interne, Hôpital Cochin, AP-HP, Paris, Ile-de-France, France

    Background/Purpose: Eosinophilic granulomatosis with polyangiitis (EGPA) is a small vessel vasculitis associated with asthma and blood and tissue eosinophilia. EGPA is often associated with glucocorticoid…
  • Abstract Number: 2570 • ACR Convergence 2024

    Comparison of the Clinical Features and Biomarker Profiles of the Childhood Arthritis and Rheumatology Research Alliance (CARRA) Systemic Juvenile Idiopathic Arthritis- Associated Lung Disease (SJIA-LD) Cohort to CARRA Registry SJIA Patients Without Lung Disease

    Esraa Eloseily1, Autumn Clark1, Min-Lee Chang2, Mary Ellen Riordan3, Alan Russell4, Marc Natter5, Scott Canna6, Sherry Thornton7, Yukiko Kimura8 and grant schulert1, and CARRA FROST Investigators and the CARRA Registry SJIA-LD Cohort Investigators, 1Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 2Computational Health Informatics Program, Boston Children’s Hospital, Boston, MA, 3Hackensack University Medical Center, Westwood, NJ, 4Duke Clinical Research Institute, Durham, NC, 5Boston Children's Hospital, Boston, MA, 6Children's Hospital of Philadelphia, Philadelphia, PA, 7Cincinnati Children's Hospital, Cincinnati, 8Hackensack Meridian School of Medicine, New York, NY

    Background/Purpose: Systemic juvenile idiopathic arthritis (SJIA) associated lung disease (SJIA-LD) is an emerging life-threatening disease with urgent unmet knowledge gaps. This study compares the clinical…
  • Abstract Number: 0715 • ACR Convergence 2024

    Diffuse Alveolar Hemorrhage in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis Revisited

    Samuel Falde1, Elif Ediboglu1, Misbah Baqir1, Rodrigo Cartin-Ceba2, Fernando C. Fervenza1, Ladan Zand1, Matthew Koster1, Kenneth Warrington1 and Ulrich Specks1, 1Mayo Clinic, Rochester, MN, 2Mayo Clinic, Scottsdale, AZ

    Background/Purpose: We sought to characterize the most recent cohort of patients presenting with DAH and AAV and to identify risk factors for respiratory failure and…
  • Abstract Number: 1693 • ACR Convergence 2024

    Change in Forced Vital Capacity at Week 12 or 24 Has Prognostic Value for Outcome at Week 52 in Patients with Autoimmune Disease-Related Interstitial Lung Diseases

    Anna-Maria Hoffmann-Vold1, Margarida Alves2, Corinna Miede3 and Oliver Distler4, 1Oslo University Hospital, Oslo, Norway, 2Boehringer Ingelheim International GmbH, Ingelheim am Rhein, Germany, Ingelheim, Germany, 3mainanalytics GmbH, Sulzbach (Taunus), Germany, Sulzbach, Germany, 4Department of Rheumatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland, Zurich, Switzerland

    Background/Purpose: Clinical trials in patients with interstitial lung diseases (ILDs) generally include a 52-week treatment period. Shorter trials would help speed up drug development and…
  • Abstract Number: 2645 • ACR Convergence 2024

    Human NCF1-p.R90H Variant Promotes Pulmonary Fibrosis in the Bleomycin-induced Mouse Model and Systemic Sclerosis Patients via Expansion of SPP1+Monocytes-derived Macrophages

    Xinran Yuan1, Xiaodong Qin2, Kenji Takemoto1, Jian Zhao1, Matthew Sanderson1, Xue Xu1, Kristi L Helke3, Bethany Wolf4, Joel Guthridge5, Judith A James6, Xiaodong Zhou7, Shervin Assassi8, Carol Feghali-Bostwick4, Dandan Wang9, Lingyun Sun10 and Betty P Tsao1, 1Division of Rheumatology and Immunology, Department of Medicine, Medical University of South Carolina, Charleston, SC, 2Department of Orthopedic Surgery, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, Jiangsu, China (People's Republic), 3Department of Comparative Medicine, Medical University of South Carolina, Charleston, SC, 4Medical University of South Carolina, Charleston, SC, 5Oklahoma Medical Research Foundation, Oklahoma City, OK, 6Arthritis and Clinical Immunology, Oklahoma Medical Research Foundation, Oklahoma City, OK, 7Division of Rheumatology, University of Texas Health Science Center at Houston, Houston, TX, 8UTHealth Houston Division of Rheumatology, Houston, TX, 9Department of Rheumatology and Immunology, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical Schoo, Nanjing, Jiangsu, China (People's Republic), 10Department of Rheumatology and Immunology, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, Jiangsu, China (People's Republic)

    Background/Purpose: We previously identified a systemic lupus erythematosus (SLE) causal risk variant, p.Arg90His (p.R90H, rs201802880) substitution encoded in neutrophil cytosolic factor 1 (NCF1), an essential component…
  • Abstract Number: 0814 • ACR Convergence 2024

    Rare Variants of PAH Risk Genes Associate with a Distinct Vasculopathy Phenotype and Worse Outcomes in Patients with Systemic Lupus Erythematosus-associated Pulmonary Arterial Hypertension

    Junyan Qian1, Xinzhuang Yang2, Yu Fang Ding3, qian wang1, Jiuliang Zhao1, Weida Liu4, Yongtai Liu5, Zhuang Tian5, Yanhong Wang6, Xiaojian Wang7, Mengtao Li1 and Xiaofeng Zeng8, 1Department of Rheumatology and Clinical Immunology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China 2National Clinical Research Center for Dermatologic and Immunologic Diseases (NCRC-DID), Ministry of Science & Technology, Beijing, China, 2Center for Bioinformatics, National Infrastructures for Translational Medicine, Institute of Clinical Medicine & Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China, 3Department of Rheumatology and Clinical Immunology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China 2National Clinical Research Center for Dermatologic and Immunologic Diseases (NCRC-DID), Ministry of Science & Technology, BEIJING, China (People's Republic), 4State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China, 5Department of Cardiology, Peking Union Medical College Hospital, Peking Union Medical College & Chinese Academy of Medical Sciences, Beijing, China, 6Department of Epidemiology and Biostatistics, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China, 7State Key Laboratory of Cardiovascular Disease, Department of Cardiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China, 8Department of Rheumatology, Peking Union Medical College Hospital (PUMCH), Chinese Academy of Medical Sciences National Clinical Research Center for Dermatologic and Immunologic Diseases (NCRC-DID), Beijing, China

    Background/Purpose: Systemic lupus erythematosus (SLE)-associated pulmonary arterial hypertension (PAH) displays significant clinical heterogeneity; nevertheless, the underlying mechanisms remain unclear. Presently, more than twenty risk genes…
  • Abstract Number: 1694 • ACR Convergence 2024

    One-Year Survival Following Single versus Double Lung Transplantation in Adults with Systemic Autoimmune Rheumatic Disease-related Interstitial Lung Disease: A Nationwide Cohort Study

    Harry Hurley1, Luke Benvenuto2 and Elana Bernstein3, 1Albert Einstein College of Medicine, Maplewood, NJ, 2Columbia University, New York, NY, 3Division of Rheumatology, Department of Medicine, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, NY

    Background/Purpose: Lung transplantation (LT) is a potentially life-saving treatment for patients with systemic autoimmune rheumatic diseases (SARDs) who have developed end-stage lung disease due to…
  • Abstract Number: 0953 • ACR Convergence 2024

    Establishment of Systemic Sclerosis Associated Pulmonary Arterial Hypertension Specific Endothelial Cells Through iPSCs and Their Functional and Molecular Analyses

    Yuki Kudo1, Masaru Kato1, Yuhei Shibata2, Ryo Hisada1, Michihito Kono1, Yuichiro Fujieda1, Olga Amengual3 and Tatsuya Atsumi1, 1Department of Rheumatology, Endocrinology and Nephrology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan, Sapporo, Japan, 2Rheumatology Department, Hokkaido Medical Center for Rheumatic Diseases, Sapporo, Japan., Sapporo, Japan, 3Department of Rheumatology, Endocrinology and Nephrology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan

    Background/Purpose: Systemic sclerosis associated pulmonary arterial hypertension (SSc-PAH) is of particularly clinical interest since its outcomes remain unfavorable despite modern PAH therapies. Previous reports showed…
  • Abstract Number: 1894 • ACR Convergence 2024

    Detection of Fibrotic Lung Changes and Bronchiectasis in RA Patients Screened for Lung Cancer with Low-dose CT Chest: Results from a Large Multi-hospital System

    Gregory McDermott1, Mark Hammer2, Xiaosong Wang3, Misti Paudel4, Sung Hae Chang5, Pierre-Antoine Juge6, Qianru Zhang7, Jessica Lorusso8, Amie Samulyov8, Kathleen Vanni2, Alene Saavedra2, Emily Kowalski2, Grace Qian3, Katarina Bade2, Kevin Mueller2, Jeffrey Sparks9 and Suzanne Byrne2, 1Brigham and Women's Hospital, Brookline, MA, 2Brigham and Women's Hospital, Boston, MA, 3Brigham and Women’s Hospital, Boston, MA, 4Brigham and Women's Hospital, Division of Rheumatology, Inflammation, and Immunity, Boston, MA, 5Soonchunhyang University College of Medicine, Bongmyeong-dong, Dongnam-gu, Cheonan-si, South Korea, 6Departement of Rheumatology, AP-HP, Bichat Hospital, Boston, MA, 7Harard Medical School, Cambridge, 8Mass General Brigham, Boston, MA, 9Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA, Boston, MA

    Background/Purpose: Cigarette smoking is a risk factor for both lung cancer and RA. Furthermore, RA is associated with pulmonary abnormalities including interstitial lung disease, bronchiectasis,…
  • Abstract Number: 0154 • ACR Convergence 2024

    Chronic Sinusitis Predicting Interstitial Lung Disease in Sjögren’s Syndrome: A Comprehensive USA Population Study (2004-2024)

    Brian Schonewald1, Ross summer2, Giorgos Loizidis2 and Christopher Xie3, 1Thomas Jefferson University Hospital, Ardmore, PA, 2Thomas Jefferson University, Philadelphia, PA, 3Thomas Jefferson University, Philadelphia

    Background/Purpose: Sjögren's syndrome (SS) is a chronic autoimmune disorder primarily affecting the exocrine glands, but it also impacts various parts of the respiratory system, including…
  • Abstract Number: 0956 • ACR Convergence 2024

    Secreted Frizzled-Related Protein 2 (sFRP2) Regulates Wnt Signaling to Affect Mesenchymal Transition of Lung Epithelial Cells Participates in Interstitial Lung Disease

    Yinlan Wu1, Yanhong Li2 and Yi Liu3, 1West China Hospital of Sichuan University, Chengdu, Sichuan, China, 2West China School of Medicine and West China Hospital, Sichuan University, Cheng Du, Sichuan, China, 3West China Hospital, Sichuan University, Chengdu, China (People's Republic)

    Background/Purpose: Investigation of Transcriptional Changes in Interstitial Lung Disease (ILD) and Exploration of Functional Effects of Differential Genes and Expressed Proteins in the Development of…
  • Abstract Number: 1976 • ACR Convergence 2024

    Artificial Intelligence Analysis of HRCT Images Reflects Pulmonary Involvement in Systemic Sclerosis Interstitial Lung Disease

    Enrico De Lorenzis1, Lucy Elizabeth Thornton2, Stefano Di Donato3, Marco Minerba3, Lesley-Anne Bissell4, Riccardo Bixio5, Anand Devaraj6, Peter George7 and Francesco Del Galdo8, 1Catholic University of the Sacred Heart, Roma, Rome, Italy, 21. Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, 2. NIHR Leeds Biomedical Research Centre, United Kingdom, Leeds, 31. Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, 2. NIHR Leeds Biomedical Research Centre, United Kingdom, Leeds, United Kingdom, 4Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom, 5University of Verona, Verona, Verona, Italy, 6Department of Radiology, Royal Brompton Hospital, London, London, United Kingdom, 7Department of Interstitial Lung Disease, Royal Brompton Hospital London, London, United Kingdom, 8University of Leeds, Leeds, United Kingdom

    Background/Purpose: Interstitial lung disease (ILD) is the leading cause of mortality and morbidity in systemic sclerosis (SSc) patients. Current functional, imaging, and clinical measures of…
  • Abstract Number: 0253 • ACR Convergence 2024

    Outcomes of Respiratory Syncytial Virus Infection in Patients with Systemic Autoimmune Rheumatic Diseases

    Justine Enns1, Shruthi Srivatsan1, Bohang Jiang1, Miao Lin1, Emily Kowalski2, Naomi Patel1, Xiaosong Wang3, Zachary Williams1, Grace Qian3, Jennifer Hanberg1, Colebrook Johnson1, Madison Negron1, Katarina Bade2, Alene Saavedra2, Kevin Mueller2, Kathleen Vanni3, Jeffrey Sparks4 and Zachary Wallace5, 1Massachusetts General Hospital, Boston, MA, 2Brigham and Women's Hospital, Boston, MA, 3Brigham and Women’s Hospital, Boston, MA, 4Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA, Boston, MA, 5Massachusetts General Hospital, Newton, MA

    Background/Purpose: Respiratory Syncytial Virus (RSV) can cause a severe respiratory illness, especially in older adults and those with significant comorbidities. In June 2023 the US…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

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