ACR Meeting Abstracts

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Abstracts tagged "pulmonary"

  • Abstract Number: 0288 • ACR Convergence 2021

    Demographic, Lifestyle, and Clinical Risk Factors for Rheumatoid Arthritis-Associated Bronchiectasis: Role of RA-related Autoantibodies

    Gregory McDermott1, Ritu Gill2, Staci Gagne3, Suzanne Byrne3, Weixing Huang3, Lauren Prisco4, Alessandra Zaccardelli3, Lily Martin3, Nancy Shadick5, Paul Dellaripa3, Tracy Doyle6 and Jeffrey Sparks3, 1Brigham and Women's Hospital, Brookline, MA, 2Beth Israel Deaconess Medical Center, Boston, MA, 3Brigham and Women's Hospital, Boston, MA, 4Brigham and Women's Hospital, Pound Ridge, MA, 5Brigham & Women's Hospital, Boston, MA, 6Brigham and Women's Hospital, West Roxbury, MA

    Background/Purpose: Bronchiectasis is a known extra-articular manifestation of rheumatoid arthritis (RA) characterized by bronchial damage and excessive mucus production that predispose patients to risk of…
  • Abstract Number: 0290 • ACR Convergence 2021

    Prevalence and Predictors of Mortality in Rheumatoid Arthritis-Related Lung Disease: Results from a Single Center Study

    Didem Sahin Eroglu1, Anil Colaklar2, Serdar Baysal3, Murat Torgutalp1, Asaf Baygul4, Serdar Sezer1, Emine Aydemir Guloksuz1, Mehmet Yuksel1, Mucteba Yayla1, Emine Uslu yurteri5, Caglar Uzun2, Ozlem Ozdemir kumbasar4, Murat Turgay1, Kinikli Gulay1 and Askin Ates1, 1Ankara University Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology, Ankara, Turkey, 2Ankara University Faculty of Medicine, Department of Radiology, Ankara, Turkey, 3Ankara University Faculty of Medicine, Department of Internal Medicine, Ankara, Turkey, 4Ankara University Faculty of Medicine, Department of Pulmonology, Ankara, Turkey, 5Hatay Training and Research Hospital, Hatay, Turkey

    Background/Purpose: Rheumatoid arthritis-related lung disease (RA-LD) is a common manifestation of rheumatoid arthritis (RA) and associated with excess mortality. Many studies to date were focused…
  • Abstract Number: 0291 • ACR Convergence 2021

    IgA Anti-Cyclic Citrullinated Peptide Antibodies in Bronchoalveolar Lavage Fluid from Patients with Idiopathic Pulmonary Fibrosis Are Associated with Reduced Mortality

    Scott Matson1, Candace Cephers2, Timothy Wilson3, Valerie Minarchick3, Kevin Brown4, Joshua Solomon4 and Kristen Demoruelle5, 1University of Kansas, Kansas City, MO, 2St Joseph Hospital, Internal Medicine, Denver, CO, 3University of Colorado, Denver, CO, 4National Jewish Health, Denver, CO, 5University of Colorado Anschutz Medical Campus, Aurora, CO

    Background/Purpose: Idiopathic pulmonary fibrosis (IPF) is a form of interstitial lung disease (ILD) that shares many clinical features with rheumatoid arthritis (RA) associated ILD. Our…
  • Abstract Number: 0497 • ACR Convergence 2021

    Efficacy in Patient Subgroups in the INCREASE Trial, a Phase III Trial to Evaluate Inhaled Treprostinil in Patients with Pulmonary Hypertension Due to Parenchymal Lung Disease

    Victor Tapson1, Steven Nathan2, Reda Girgis3, James Runo4, Remzi Bag5, Arunabh Talwar6, Peter Smith7, Lisa Edwards7, Christine Park7 and Aaron Waxman8, 1Cedars-Sinai, Los Angeles, CA, 2Inova Fairfax, Falls Church, VA, 3Michigan State University, Lansing, MI, 4University of Wisconsin, Madison, WI, 5University of Chicago, Chicago, IL, 6Hofstra Northwell School of Medicine, Hempstead, NY, 7United Therapeutics Corporation, Durham, NC, 8Brigham and Women's Hospital, Boston, MA

    Background/Purpose: INCREASE was a 16-week trial evaluating the safety and efficacy of inhaled treprostinil (iTRE) in patients with pulmonary hypertension associated with interstitial lung disease…
  • Abstract Number: 0505 • ACR Convergence 2021

    Risk of Venous and Arterial Thromboembolism in Patients with Giant Cell Arteritis And/or Polymyalgia Rheumatica: A Veterans Health Administration Population-Based Study in the United States

    Despina Michailidou1, Tianyu Zhang2, Pavlos Stamatis3 and Bernard Ng4, 1Division of Rheumatology, University of Washington, Seattle, WA, 2Department of Biostatistics, University of Washington, Seattle, WA, 3Lund University, Lund, Sweden, 4Rheumatology Section, VA Puget Sound HCS, University of Washington, Seattle, WA

    Background/Purpose: Giant cell arteritis (GCA) and polymyalgia rheumatica (PMR) are two chronic systemic inflammatory diseases that primarily affect elderly women. Both diseases can be complicated…
  • Abstract Number: 1002 • ACR Convergence 2021

    Nerve and Airway-associated Tissue Resident Pulmonary Macrophages Limit Infiltration and Alter Phenotype of Infiltrating Monocytes and Fibrocytes to Reduce Pulmonary Fibrosis

    Robert Freilich1 and Kamal Khanna2, 1New York University Department of Rheumatology, New York, NY, 2New York University Department of Rheumatology & Microbiology, New York, NY

    Background/Purpose: Macrophages and monocytes are increasingly implicated in the pathogenesis of autoimmune induced pulmonary fibrosis. In addition to the well-recognized classes of tissue resident macrophages…
  • Abstract Number: 1100 • ACR Convergence 2021

    Pulmonary Arterial Hypertension in Adult-Onset Still’s Disease: A Case Series of 13 Patients

    Stéphane Mitrovic1, athénaïs Boucly2, Estibaliz Lazaro3, Nicolas SCHLEINITZ4, Coralie Bloch-Queyrat5, Christine Christides6, Jacques Pouchot7, marc humbert2, David Montani2, laurent savale2, Xavier Jaïs2, Olivier Sitbon2 and Bruno Fautrel8, 1Pitié Salpêtrière Hospital - Institut Mutaliste Montsouris, Paris, France, 2Pneumology Department, Bicêtre Hospital, Assistance Publique – Hôpitaux de Paris, Kremlin-Bicêtre, France, 3Internal Medicine Department, CHU Bordeaux, Pessac, France, 4Internal Medicine Department, Hôpital Timone, APHM, Marseille, France, 5Internal Medicine Department, Avicennes Hospital, APHP, Bobigny, France, 6Internal Medicine Department, CH Avignon, Avignon, France, 7AP-HP, RUEIL-MALMAISON, France, 8Pitié Salpêtrière Hospital, APHP, Sorbonne Université, Paris, France

    Background/Purpose: Pulmonary Arterial Hypertension (PAH) is a rare but potentially fatal complication of Adult-Onset Still's Disease (AOSD). To date, only isolated observations have been published.…
  • Abstract Number: 1370 • ACR Convergence 2021

    Complement Factor D and Factor H Represent Disease and Severity Biomarkers for Systemic Sclerosis Associated Pulmonary Arterial Hypertension (SSc-PAH)

    Roberta G Marangoni1, Changyong Feng1, Ashley Frazer-Abel2, Stephen Tomlinson3, Amy Wielgosz1, Katie Lutz4, Michael Pauciulo4, William Nichols4, V. Michael Holers5, Christopher Ritchlin6, R James White III1 and Benjamin Korman1, 1University of Rochester, Rochester, NY, 2University of Colorado Denver, Colorado, CO, 3Medical University of South Carolina, Charleston, SC, 4Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 5University of Colorado, Denver, CO, 6Division of Allergy, Immunology, and Rheumatology, School of Medicine and Dentistry, University of Rochester Medical Center, Rochester, NY

    Background/Purpose: Pulmonary arterial hypertension (PAH) is a severe vascular complication of systemic sclerosis (SSc) and a major cause of mortality. Despite significant advances in the…
  • Abstract Number: L04 • ACR Convergence 2020

    Influenza Adverse Events in Patients with Rheumatoid Arthritis in the Tofacitinib Clinical Program

    Kevin L Winthrop1, Arne Yndestad2, Dan Henrohn3, Hyejin Jo4, Sara Marsal5, Maria Galindo6, Annette Diehl7, Andrea B Shapiro8 and Stanley B Cohen9, 1Oregon Health & Science University, Portland, OR, 2Pfizer Inc, Oslo, Norway, 3Pfizer Inc, Sollentuna, Sweden, 4Syneos Health, Raleigh, NC, 5Vall d’Hebron Hospital, Barcelona, Spain, 6Rheumatology Unit, Hospital Universitario 12 de Octubre, Madrid, Spain, 7Pfizer Inc, Collegeville, PA, 8Pfizer Inc, Peapack, NJ, 9Metroplex Clinical Research Center, Dallas, TX

    Background/Purpose: Patients (pts) with RA have increased susceptibility to seasonal influenza and its complications.1 The COVID-19 pandemic highlights the need to understand acute respiratory RNA…
  • Abstract Number: 0491 • ACR Convergence 2020

    Relationship Between Rheumatoid Arthritis and Pulmonary Function in the UK Biobank

    Lauren C. Prisco1, Matthew Moll1, Jiaqi Wang2, Weixing Huang3, Lily Martin1, Vanessa Kronzer4, Sicong Huang2, Edwin Silverman2, Tracy J. Doyle5, Michael Cho5 and Jeffrey Sparks6, 1Brigham and Women's Hospital, Boston, 2Brigham and Women's Hospital, Boston, MA, 3Division of Rheumatology, Inflammation, and Immunity; Brigham and Women’s Hospital and Harvard Medical School, Boston, 4Mayo Clinic, Rochester, MN, 5Brigham and Women's Hospital, West Roxbury, MA, 6Division of Rheumatology, Inflammation, and Immunity; Brigham and Women’s Hospital and Harvard Medical School, Boston, MA

    Background/Purpose: Established pulmonary manifestations of RA include restrictive processes such as interstitial lung disease and obstructive processes such as bronchiectasis, but clinically detected forms of…
  • Abstract Number: 1694 • ACR Convergence 2020

    Risk Factors Associated with Pneumocystis Jirovecii Pneumonia in Juvenile Myositis in North America

    Sara Sabbagh1, Jessica Neely2, Albert Chow3, Marietta DeGuzman4, Jamie Lai5, Svetlana Lvovich6, Tara McGrath7, Maria Pereira8, Iago Pinal-Fernandez9, Jordan Roberts10, Kelly Rouster-Stevens11, Heinrike Schmeling12, Anjali Sura13, Gabriel Tarshish14, Lori Tucker15, Lisa G. Rider16 and Susan Kim17, 1Medical College of Wisconsin, Fox Point, WI, 2UCSF, San Francisco, CA, 3Loma Linda University, San Bernardino, CA, 4Baylor College of Medicine, Houston, 5University of Colorado, The Woodlands, TX, 6St Christopher's Hospital for Children, Philadelphia, PA, 7University of British Columbia, Vancouver, BC, Canada, 8Baylor College of Medicine, Houston, TX, 9National Institutes of Health, Bethesda, MD, 10Boston Children's Hospital, Boston, MA, 11Emory University/Children's Healthcare of Atlanta, Atlanta, GA, 12University of Calgary, Calgary, AB, Canada, 13Upstate University Hospital, Syracuse, NY, 14Children's Hospital at Montefiore, New York, NY, 15BC Children's Hospital, Vancouver, BC, Canada, 16Environmental Autoimmunity Group, Clinical Research Branch, NIEHS, NIH, Garrett Park, MD, 17UCSF Benioff Children's Hospital, San Francisco, CA

    Background/Purpose: Pneumocystis jirovecii pneumonia (PJP) is associated with significant morbidity and mortality in adult myositis patients; however, few studies have examined PJP in juvenile myositis…
  • Abstract Number: 0520 • ACR Convergence 2020

    Antiphospholipid Antibodies and Thrombotic Events in COVID-19 Patients Hospitalized in Medicine Ward

    Alexandre Le Joncour1, Corinne Frere1, Isabelle Martin-Toutain1, Paul Gougis1, Pascale Ghillani-Dalbin1, Georgina Maalouf1, Matheus Vieira1, Anne-Genevieve Marcelin1, Joe-Elie Salem1, Yves Allenbach2, David Saadoun3, Olivier Benveniste4 and Patrice Cacoub1, 1APHP, paris, France, 2Sorbonne Université, Paris, Ile-de-France, France, 3AP-HP, Groupe Hospitalier Pitié-Salpêtrière, Department of Internal Medicine and Clinical Immunology, F-75013, Paris, France, Centre national de références Maladies Autoimmunes et systémiques rares et Maladies Autoinflammatoires rares, PAris, France, 4Sorbonne Université, paris, France

    Background/Purpose: A high prevalence of thrombotic events has been reported in critically ill COVID-19 patients but data on the prevalence of thrombosis in ward patients…
  • Abstract Number: 1695 • ACR Convergence 2020

    Anti-Melanoma Differentiation Associated Protein 5 (MDA5) Positive Juvenile Dermatomyositis: Focus on the Lung

    David Moreno McNeill1, Miriah Gillispie-Taylor2, Kevin Baszis3, Edouard Sayad1, Manuel Silva Carmona1 and Tiphanie Vogel1, 1Baylor College of Medicine/Texas Children's Hospital, Houston, TX, 2Baylor College of Medicine, Houston, 3Washington Univ School of Medicine, St Louis, MO

    Background/Purpose: A subset of juvenile dermatomyositis (JDM), clinically amyopathic dermatomyositis (CADM), is uncommon and mainly described in adults. CADM is classically characterized by skin ulcerations,…
  • Abstract Number: 0785 • ACR Convergence 2020

    Identification of Recruited CCR2+ Inflammatory Monocytes in a Mouse Model of RA-associated Lung Disease with Potential Role for resolvin-D1 in Reducing Monocyte Inflammatory Responses

    Austin Barry1, Geoffrey Thiele1, Ted Mikuls1, Michael Duryee1, Amy Nelson1, Rohit Gaurav1, Bryant England1 and Jill Poole1, 1University of Nebraska Medical Center, Omaha, NE

    Background/Purpose: Patients with rheumatoid arthritis (RA) are at an increased risk for comorbid chronic lung disease, with premature mortality. Therapies for RA-associated lung disease are…
  • Abstract Number: 1908 • ACR Convergence 2020

    Establishment of iPSc and Differentiated Endothelial Cells of Systemic Sclerosis Associated Pulmonary Arterial Hypertension ; Functional and Molecular Analysis

    Yuki Kudo1, Masaru Kato2, Yuhei Shibata1, Michihito Kono2, Yuichiro Fujieda2, Olga Amengual2, Kenji Oku2 and Tatsuya Atsumi3, 1Department of Rheumatology, Endocrinology and Nephrology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan, 2Department of Rheumatology, Endocrinology and Nephrology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Hokkaido, Japan, 3Department of Rheumatology, Endocrinology and Nephrology, Faculty of Medicine, Hokkaido University, Sapparo, Hokkaido, Japan

    Background/Purpose: Pulmonary arterial hypertension (PAH) occurs either primarily or in association with other diseases such as connective tissue diseases. PAH associated with systemic sclerosis (SSc-PAH)…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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