Abstracts tagged "Pulmonary Involvement"

Abstract Number: 1931 • 2014 ACR/ARHP Annual Meeting
Mycophenolate Mofetil (MMF) Use in Scleroderma Patients with Pulmonary Hypertension: Observations from the Pulmonary Hypertension Assessment and Recognition of Outcomes in Scleroderma Cohort
Lesley Ann Saketkoo¹, Matthew R. Lammi², Aryeh Fischer³, Jerry A. Molitor⁴ and Virginia D. Steen⁵, ¹Scleroderma and Sarcoidosis Patient Care and Research Center, Rheumatology and Pulmonary Medicine, Louisiana State University Health Sciences Center, New Orleans, LA, ²Louisiana State University Health Sciences Center, Pulmonary and Critical Medicine, New Orleans, LA, ³Rheumatology / ILD Program, National Jewish Health, Denver, CO, ⁴Rheumatology, University of Minnesota, Minneapolis, MN, ⁵Department of Rheumatology, Georgetown University Medical Center, Washington, DC
Background/Purpose: Systemic sclerosis (SSc) related pulmonary hypertension (PH) carries a high mortality and patients with SSc-PH related to restrictive lung disease having an even worse…
Abstract Number: 1696 • 2014 ACR/ARHP Annual Meeting
Left Atrial Area Measurement Is Useful for Evaluating Left Ventricular Diastolic Dysfunction Coexisting with Pulmonary Arterial Hypertension Associated with Systemic Sclerosis
Sumiaki Tanaka¹, Nobuhiro Sho², Tatsuo Nagai³, Yoshiyuki Arinuma² and Shunsei Hirohata¹, ¹Int Med/Rheumatol & Infec Dis, Kitasato University School of Medicine, Sagamihara, Japan, ²Kitasato University School of Medicine, Sagamihara, Japan, ³Department of Rheumatology and Infectious Diseases, Kitasato University School of Medicine, Sagamihara, Japan
Background/Purpose: Pulmonary arterial hypertension (PAH) is a crucial organ involvement affecting survival of patients with connective tissue disease (CTDs), such as systemic sclerosis (SSc), systemic…
Abstract Number: 1692 • 2014 ACR/ARHP Annual Meeting
The Additive Value of Nailfold Videocapillaroscopy Patterns to Disease-Specific Autoantibodies in Discrimination of Patients with Systemic Sclerosis at Risk for Severe Organ Involvement
I.M. Markusse¹, J. Meijs², B. de Boer², A. a. Schouffoer¹, N. Ajmone Marsan³, L. J. M. Kroft⁴, M. K. Ninaber⁵, T. W. J. Huizinga² and J.K. de Vries-Bouwstra⁶, ¹Leiden University Medical Center, Leiden, Netherlands, ²Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ³Cardiology, Leiden University Medical Center, Leiden, Netherlands, ⁴Deparment of Radiology, Leiden University Medical Center, Leiden, Netherlands, ⁵Pulmonology, Leiden University Medical Center, Leiden, Netherlands, ⁶Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands
Background/Purpose: Severe nailfold videocapillaroscopy (NVC) patterns in patients with systemic sclerosis (SSc) are associated with a high risk of organ involvement. SSc-specific autoantibodies seem to…
Abstract Number: 1441 • 2014 ACR/ARHP Annual Meeting
Accelerated Aging in DMARD and Treatment Naive Early Rheumatoid Arthritis Patients Measured By a Stem Cell Assay Is Associated with Increased LDL and Is Linked to Impaired Cardiopulmonary Function
Torkell Ellingsen^1,2,3, Henriette Jørgensen⁴, Dino Demirovic⁴, Lone Deibjerg⁵, Frank Andersen⁵, Agnete Hedemann-Andersen⁵, Brian Bridal Løgstrup^5,6 and Suresh Rattan⁴, ¹Diagnostic Centre Region, Hospital Silkeborg Denmark, Odense, Denmark, ²The Danish National Registry DANBIO, Odense, Denmark, ³Department of Rheumatology, Odense University Hospital, Denmark, Odense, Denmark, ⁴Laboratory of Cellular Ageing, Institute of Molecular Biology and Genetics, Århus University, Århus, Denmark, ⁵Diagnostic Centre Region, Hospital Silkeborg Denmark, Silkeborg, Denmark, ⁶Cardiology, Skejby Hospital, Århus Universityhosital, Århus, Denmark
Background/Purpose: The cardiovascular comorbidity seen in early treatment naive rheumatoid arthritis (RA) can be considered as an aspect of ´´accelerated aging``. Methods: We investigated cell…
Abstract Number: 724 • 2014 ACR/ARHP Annual Meeting
Moderate Decline in Forced Vital Capacity is Associated with a Poor Outcome in Systemic Sclerosis Patients
Anna-Maria Hoffmann-Vold¹, Oyvind Midtvedt², Torhild Garen³, May Brit Lund⁴, T. Mogens Aalokken⁵, Jan Tore Gran² and Oyvind Molberg⁶, ¹Department of Rheumatology, Department of Rheumatology, Oslo University Hospital Rikshospitalet, Oslo, Norway, ²Rheumatology, Oslo University Hospital, Oslo, Norway, ³Department of Rheumatology, Oslo University Hospital Rikshospitalet, Oslo, Norway, ⁴Department of Respiratory Medicine, Oslo University Hospital Rikshopitalet, Oslo, Norway, ⁵Department of Radiology, Oslo University Hospital Rikshospitalet, Oslo, Norway, ⁶Department of Rheumatology, Oslo University Hospital, Rikshospitalet, Oslo, Norway
Background/Purpose: Interstitial lung disease (ILD) is a common manifestation in systemic sclerosis (SSc) and the leading cause of morbidity and mortality. Serial pulmonary function tests…
Abstract Number: 2610 • 2013 ACR/ARHP Annual Meeting
A New Pathogenic Role Of BAFF As a Critical Mediator Of Skin and Lung Fibrosis In Experimental Bleomycin-Induced Pulmonary Fibrosis, Systemic Sclerosis and Idiopathic Pulmonary Fibrosis
Antoine Francois¹, Pascal Schneider², Anne Davidson³, Emmanuel Chatelus⁴, Jérôme Avouac⁵, Yannick Allanore⁶, Bérengère Villeret⁷, Aurélie Gombault⁷, Paméla Gasse⁸, Sylvain Marchand Adam⁹, Bernhard Ryffel¹⁰, Siamak Bahram¹¹, Philippe Georgel¹², Jean Sibilia¹³, Isabelle Couillin⁸ and Jacques-Eric Gottenberg¹⁴, ¹Laboratory of Physiopathology of Arthritises, University of Strasbourg, Illkirch-Strasbourg, France, ²Department of Biochemistry, University of Lausanne, Lausanne, Switzerland, ³Autoimmunity and Musculoskeletal Diseases, Feinstein Institute for Medical Research, Manhasset, NY, ⁴Rheumatology, Strasbourg University Hospital, Strasbourg, France, ⁵Paris Descartes University, Rheumatology A department, Cochin Hospital, Paris, France, ⁶Rheumatology, Paris Descartes University, Rheumatology A department, Cochin Hospital, Paris, France, ⁷Molecular Immunology and Embryology, University of Orleans and National Center for Scientific Research, Orléans, France, ⁸Molecular Immunology and Embryology, University of Orleans and National Center for Scientific Research, Orleans, France, ⁹Francois Rabelais University, National institute of the health and the medical research, Tours, France, ¹⁰UMR6218, Molecular Immunology, University and CNRS, 3b rue de la Ferollerie, Orleans, France, ¹¹Fédération of Translational Medicine of Strasbourg (FMTS), Immunorhumatology Molécular, Strasbourg, France, ¹²Université de Strasbourg, Laboratoire d'ImmunoGénétique Moléculaire Humaine, Strasbourg, France, ¹³Rheumatology, CHU Hautepierre, Strasbourg, France, ¹⁴Strasbourg University Hospital, Strasbourg, France
Background/Purpose: Interstitial pneumonitis and lung fibrosis are frequent systemic complications of inflammatory arthritides, including systemic sclerosis (SSc), rheumatoid arthritis, or primary Sjögren’s syndrome. B lymphocytes…
Abstract Number: 2582 • 2013 ACR/ARHP Annual Meeting
Treatment Of Pulmonary Hypertension In Scleroderma Patients With Restricitive Lung Disease.Observations From The Pulmonary Hypertension Assessment and Recognition Of Outcomes In Scleroderma Cohort
Virginia D. Steen¹ and Robyn T. Domsic², ¹Department of Rheumatology, Georgetown University Medical Center, Washington, DC, ²Medicine - Rheumatology, University of Pittsburgh, Pittsburgh, PA
Background/Purpose: Trials of therapy in pulmonary hypertension(PH) have generally excluded patients with significant interstitial lung disease, but many patients with systemic sclerosis(SSc) and PH have…
Abstract Number: 2574 • 2013 ACR/ARHP Annual Meeting
Early Use of Prostacyclin Therapy Improves Transplant-Free Survival in Patients With Systemic Sclerosis-Related Pulmonary Arterial Hypertension Plus Interstitial Lung Disease
Elizabeth Volkmann¹, Rajan Saggar², Bryant Torres¹, Lynne Yoder², Robert Elashoff³, Rajeev Saggar⁴, Harsh Agrawal¹, Nabeel Borazan⁵, Sarah Thomas¹ and Daniel Furst¹, ¹Medicine, University of California, Los Angeles, Los Angeles, CA, ²Medicine, University of California, Los Angeles, David Geffen School of Medicine, Los Angeles, CA, ³Biomath, University of California, Los Angeles, Los Angeles, CA, ⁴Critical Care Medicine, St. Joseph's Hospital and Medical Center, Phoenix, AZ, ⁵Medicine, Rheumatology UCLA, Los Angeles, CA
Background/Purpose: The leading causes of death in systemic sclerosis (SSc) are pulmonary arterial hypertension (PAH) and interstitial lung disease (ILD). Use of PAH therapy in…
Abstract Number: 2575 • 2013 ACR/ARHP Annual Meeting
Utility Of Autoantibody Testing For Predicting Risk Of Pulmonary Arterial Hypertension: A Retrospective Analysis In Routine Autoantibody Laboratory
Masataka Kuwana¹, Yuichiro Shirai¹, Hidekata Yasuoka¹, Tsutomu Takeuchi¹ and Kenichi Masui², ¹Division of Rheumatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan, ²Department of Anesthesiology, National Defense Medical College, Tokorozawa, Japan
Background/Purpose: Pulmonary arterial hypertension (PAH) is an intractable complication of connective tissue disease (CTD). Current guidelines recommend early detection and intervention for improvement of outcomes.…
Abstract Number: 2580 • 2013 ACR/ARHP Annual Meeting
Does Mycophenolate Mofetil (MMF) Have An Effect On Pulmonary Hemodynamics? Observations From The Pulmonary Hypertension Assessment and Recognition Of Outcomes In Scleroderma (PHAROS) Cohort
Lesley Ann Saketkoo¹, Matthew R. Lammi², Jessica K. Gordon³, Paula Lauto⁴ and Virginia D. Steen⁵, ¹LSU Scleroderma and Sarcoidosis Patient Care and Research Center, New Orleans, LA, ²Section of Pulmonary and Critical Care Medicine, LSU Scleroderma and Sarcoidosis Patient Care and Research Center, New Orleans, LA, ³Rheumatology, Hospital for Special Surgery, New York, NY, ⁴Pulmonary and Critical Care Medicine, LSU Health Sciences Center, New Orleans, LA, ⁵Department of Rheumatology, Georgetown University Medical Center, Washington, DC
Does Mycophenolate Mofetil (MMF) have an effect on Pulmonary Hemodynamics? Observations from the Pulmonary Hypertension Assessment and Recognition of Outcomes in Scleroderma (PHAROS) CohortBackground/Purpose: Systemic…
Abstract Number: 2585 • 2013 ACR/ARHP Annual Meeting
Left Ventricular Dysfunction Reflected By Higher Serum Brain Natriuretic Peptide Accounts For Poorer Prognosis Of Pulmonary Arterial Hypertension Associated With Systemic Sclerosis
Sumiaki Tanaka¹, Yoshiyuki Arinuma¹, Tatsuhiko Wada¹, Tatsuo Nagai², Jun Okada³ and Shunsei Hirohata¹, ¹Int Med/Rheumatol & Infec Dis, Kitasato University School of Medicine, Sagamihara, Japan, ²Rheumatology and Infectious Diseases, Kitasato University School of Medicine, Sagamihara, Japan, ³Nutritional management, Kitasato Junior Collage of health and Hygienic Sciences, Minami-Uonuma, Japan
Background/Purpose: Recentry, development of potent effective newer drugs for pulmonary arterial hypertension (PAH) have resulted in improving survival of the patients. However, the prognosis of…
Abstract Number: 2072 • 2013 ACR/ARHP Annual Meeting
Decreased Number Of Circulating NK Cells and Dramatic Lack Of IFN-Gamma Production In Patients With Antisynthetase Syndrome
Baptiste Hervier^1,2, Yves Allenbach^3,4, Fleur Cohen-Aubart⁵, Micheline Pha⁶, Lenaig Mescam-Mancini⁷, David Saadoun⁸, Alexis Mathian^5,6, Olivier Benveniste^9,10 and Vincent Vieillard¹, ¹INSERM UMR-S 1135, UPMC, Paris, France, ²Internal Medicine & Clinical Immunology Dpt, Pitié-Salpêtrière Hospital, APHP, Paris, France, ³Internal Medicine Dpt 1, Pitié-Salpêtrière Hospital, APHP, Paris, France, ⁴INSERM UMR974, UPMC, Paris, France, ⁵Internal Medicine Dpt 2, Pitié-Salpêtrière Hospital, APHP, Paris, France, ⁶INSERM UMR-S 945, UPMC, Paris, France, ⁷Pathology Dpt, University hospital, Grenoble, France, ⁸DHU 2iB Internal Medicine Referal Center for Autoimmune diseases Pitie Hospital, Paris, France, ⁹UMR 974, Sorbonne Universités, University Pierre et Marie-Curie-Paris 6, INSERM, Paris, France, ¹⁰Internal Medecine Dpt 1, Pitié-Salpêtrière Hospital, APHP, Paris, France
Background/Purpose: Antisynthetase syndrome (ASS) is a rare autoimmune myositis associated with interstitial lung disease (ILD) and characterized by specific anti-tRNA-synthetase autoantibodies (ARS). To date, the…
Abstract Number: 2052 • 2013 ACR/ARHP Annual Meeting
The Prevalence and Pattern Of Self Reported Joint Symptoms In Cystic Fibrosis
Carl Orr¹, Cormac McCarthy¹, Johan Meurling¹, Paul G. O'Connell², Cedric Gunaratnam^1,3 and Noel G McElvaney¹, ¹Department of Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland, ²Rheumatology, Beaumont Hospital, Dublin, Ireland, ³Department of Respiratory Medicine, Beaumont Hospital, Dublin, Ireland
Background/Purpose: Arthritis in cystic fibrosis (CF) can be very incapacitating, and it is mainly of three types: CF arthritis, hypertrophic osteoarthropathy, and arthritis due to…
Abstract Number: 2012 • 2013 ACR/ARHP Annual Meeting
Gender Influences On Organ Manifestations In a New Orleans Sarcoidosis Population
Adam Janot¹, McCall Walker², Mary Yu¹, Harmanjot K. Grewal³, Matthew R. Lammi^4,5 and Lesley Ann Saketkoo^6,7, ¹Internal Medicine, Louisiana State University Health Sciences Center, New Orleans, LA, ²LSUHSC School of Medicine, New Orleans, LA, ³Rheumatology, Lousiana State University Health Sciences Center, New Orleans, LA, ⁴Section of Pulmonary and Critical Care Medicine, LSU Scleroderma and Sarcoidosis Patient Care and Research Center, New Orleans, LA, ⁵Louisiana State University Health Sciences Center, Pulmonary and Critical Medicine, New Orleans, LA, ⁶LSU Scleroderma and Sarcoidosis Patient Care and Research Center, New Orleans, LA, ⁷Scleroderma and Sarcoidosis Patient Care and Research Center, Rheumatology and Pulmonary Medicine, Louisiana State University Health Sciences Center, New Orleans, LA
Background/Purpose: Sarcoidosis is a multi-organ disease in which pulmonary manifestations predominate. The skin, eyes, heart, gastrointestinal tract (GI), reticuloendothelial, renal and nervous systems are also…
Abstract Number: 1936 • 2013 ACR/ARHP Annual Meeting
Quality Of Care In Patients At Risk For Pulmonary Involvement: Assessment Of Pulmonary Screening In Systemic Sclerosis and Myositis Patients In a General Rheumatology Clinic
Michael G. Indelicato¹, Janet E. Lewis², Vincent J. Giuliano³ and Donald L. Kimpel⁴, ¹Rheumatology, University of Virginia, Charlottesville, VA, ²Rheumatology, University of Virginia School of Medicine, Charlottesville, VA, ³University of Virginia, Charlottesville, VA, ⁴Rheumatology and Immunology, University of Virginia School of Medicine, Charlottesville, VA
Background/Purpose: As a quality assessment tool to evaluate patient care in a general Rheumatology Clinic, we determined the frequency of screening for pulmonary hypertension and…

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