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Abstracts tagged "prognostic factors"

  • Abstract Number: 0432 • ACR Convergence 2022

    Predictive Factors of Eosinophilic Granulomatosis with Polyangiitis Long-term Evolution: Data from a European Cohort

    Matthias Papo1, Pauline Martinot2, Renato A. Sinico3, Vitor Teixeira4, Nils Venhoff5, Maria-Letizia Urban6, Juliane Mahrhold7, Francesco Locatelli8, Giulia Cassone9, Franco Schiavon10, Benjamin Seeliger11, Thomas Neumann12, Claus Kroegel13, Matthieu Groh14, Chiara Marvisi15, Maxima Samson16, Thomas Barba17, David Jayne18, Arianna Troilo19, Jens Thiel20, Bernhard Hellmich21, Sara Monti22, Carlomaurizio Montecucco8, Carlo Salvarani23, Jean-Emmanuel Kahn24, Cecile-Audrey DUREL25, Luc Mouthon26, Loïc Guillevin26, Giacomo Emmi27, Augusto Vaglio28, Raphaël Porcher29 and Benjamin Terrier26, 1Service De Médecine Interne - Hôpital Cochin, Paris, France, 2Centre of Research in Epidemiology and Statistics, Université de Paris, Paris, Île-de-France, France, Paris, 3Department of Medicine and Surgery, Università degli Studi di Milano – Bicocca, Italy, Milano, Italy, 4Hospital de Faro, CHUA, Lisbon, Portugal, 5Department of Rheumatology and Clinical Immunology, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany, 6Department of Experimental and Clinical Medicine, University of Firenze, Firenze, Italy, 7Department of Internal Medicine, Rheumatology and Immunology, Medius Kliniken, University of Tübingen, Kirchheim Teck, Germany, 8Department of Rheumatology, IRCCS Policlinico S. Matteo Foundation, University of Pavia, Pavia, Italy, 9Università di Modena e Reggio Emilia, Modena, Italy, 10Operative Unit of Rheumatology, Department of Medicine DIMED, University of Padova, Padova, Italy, 11Department of Respiratory Medicine, Hannover Medical School, Wermsdorf, Germany, 12Kantonsspital St. Gallen, St. Gallen, Switzerland, 13Department of Pneumology and Allergology, Clinic of Internal Medicine I, Jena University Hospital, Jena, Germany, 14Service de Médecine Interne, Centre de Référence des Syndromes Hyperéosinophiliques-CEREO, Hôpital Foch, Université Versailles–Saint-Quentin-en-Yvelines, Suresnes, France, 15Università di Modena e Reggio Emilia and National Institute of Arthritis & Musculoskeletal & Skin Diseases, National Institutes of Health, Bethesda, MD, 16Dijon University Hospital, Dijon, France, 17Department of Internal Medicine, Hôpital Edouard Herriot, Lyon, France, 18University of Cambridge, Cambridge, United Kingdom, 19Department of Rheumatology and Clinical Immunology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany, 20University Hospital Freiburg, Freiburg, Germany, 21Klinik für Innere Medizin, Rheumatologie & Immunologie, Medius Kliniken, Universität Tübingen, Plochingen, Germany, 22Rheumatology, Fondazione IRCCS Policlinico S. Matteo, University of Pavia, Pavia, Italy, 23Azienda USL -IRCCS di Reggio Emilia and Università di Modena e Reggio Emilia, Reggio Emilia, Reggio Emilia, Italy, 24Service de médecine interne - Hôpital Ambroise Paré, AP-HP, Boulogne-Billancourt, France, 25CHU Lyon, Lyon, France, 26National Referral Center for Rare Systemic Autoimmune Diseases, Cochin Hospital, Paris, France, 27Azienda Ospedaliero Universitaria Careggi, Firenze, Italy, 28Azienda Ospedaliero Universitaria Meyer, Parna, Italy, 29Université Paris Cité, Hôtel-Dieu, Paris, France

    Background/Purpose: Eosinophilic granulomatosis with polyangiitis (EGPA) is a small vessel necrotizing vasculitis characterized by blood and tissue eosinophilia and asthma. Glucocorticoids (GCs) frequently control the…
  • Abstract Number: 1262 • ACR Convergence 2022

    Clinical and Ultrasound-based Composite Disease Activity Indices and Radiographic Progression in Rheumatoid Arthritis

    Irina Gessl1, Thomas Deimel1, Paul Studenic1, Giorgio Tamborrini2, Pascal Zufferey3, Daniel Aletaha4, Burkhard Moeller5 and Peter Mandl1, 1Medical University of Vienna, Vienna, Austria, 2Ultrasound Center and Institute for Rheumatology, Zürich, Switzerland, 3HFR, Fribourg, Switzerland, 4Medical University Vienna, Wien, Austria, 5Inselspital - University Hospital Bern, Bern, Switzerland

    Background/Purpose: Musculoskeletal ultrasound (US) has been reported to predict radiographic progression in rheumatoid arthritis (RA). The aim of the study was to test the predictive…
  • Abstract Number: 2204 • ACR Convergence 2022

    Interosseous Tendon Inflammation in the Hands: A Novel Feature of Developing Rheumatoid Arthritis? Results from a Large MRI Study in Clinically Suspect Arthralgia

    Bastiaan van Dijk1, Hanna van Steenbergen1, Monique Reijnierse2, Sarah J.H. Khidir2, Lambertus Wisse1, Marco deRuiter1 and Annette van der Helm-van Mil3, 1Leiden University Medical Centre (LUMC), Leiden, Netherlands, 2Leiden University Medical Center, Leiden, Netherlands, 3Leiden University Medical Center, Erasmus Medical Center, Leiden, Netherlands

    Background/Purpose: Inflammation around the tendons of hand interosseous muscles (interosseous tendon inflammation; ITI) on MRI was recently reported for the first time in rheumatoid arthritis…
  • Abstract Number: 0458 • ACR Convergence 2022

    Predictive Models for Thromboembolic Events in Giant Cell Arteritis: A US Veterans Health Administration Population-Based Study

    Despina Michailidou1, Tianyu Zhang2, Andreas Diamantopoulos3, Pavlos Stamatis4 and Bernard Ng5, 1Division of Rheumatology, University of Washington, Seattle, WA, 2Department of Biostatistics, University of Washington, Seattle, WA, 3Akershus University Hospital, Lørenskog, Norway, 4Department of Clinical Sciences Lund, Rheumatology, Lund University, Sweden, Larissa, Larisa, Greece, 5Rheumatology Section, VA Puget Sound Healthcare System, Seattle, WA

    Background/Purpose: Giant cell arteritis (GCA) is an independent risk factor for thromboembolic events. The purpose of our study was to identify prognostic factors for thromboembolic…
  • Abstract Number: 1264 • ACR Convergence 2022

    Does Vein Wall Thickness Have Prognostic Value in Behcet’s Disease? A Prospective Follow up Study

    Kerem Abacar1, Rabia Ergelen2, Fatma Temiz2, Yasin Yildiz2, Tulin Ergun3, Haner Direskeneli4 and Fatma Alibaz-Oner1, 1Marmara University, Rheumatology, Istanbul, Turkey, 2Marmara University, School of Medicine, Departmant of Internal Medicine, Istanbul, Turkey, 3Marmara University, School of Medicine, Department of Dermatology, Istanbul, Turkey, 4Marmara University, Rheumatology, Istanbul, Istanbul, Turkey

    Background/Purpose: We reported the first controlled ultrasound study showing increased common femoral vein(CFV) thickness in Behçet's Disease(BD),1 and showed that this is a distinctive feature…
  • Abstract Number: 0469 • ACR Convergence 2022

    Factors Associated with Corticosteroid Dosing in the Management of Giant Cell Arteritis

    Loukas Kakoullis and Shiv Sehra, Mount Auburn Hospital, Cambridge, MA

    Background/Purpose: Corticosteroids are the cornerstone of therapy in patients with giant cell arteritis (GCA). Tapering regiments vary considerably in both dose and duration, while relapses…
  • Abstract Number: 1319 • ACR Convergence 2022

    Prognostic Utility of Metacarpal Bone Mineral Density Measurement in Patients with Recent-onset Arthritis by Assessment of Radiographic Progression at 2-year Follow Up

    Irene Maria Llorente Cubas1, Ana Maria Fernandez Ortiz2, Jesus Alberto Garcia Vadillo1, Jose ivorra Cortes3, Luis Rodriguez-Rodriguez4, Rosario Garcia-Vicuña5, Santos Castañeda6, Isidoro Gonzalez1 and Ana M Ortiz1, 1Hospital Universitario de La Princesa, Madrid, Spain, 2Hospital Universitario de Badajoz, Badajoz, Spain, 3Hospital Universitario de La Fe, València, Spain, 4Instituto de Investigación Sanitaria San Carlos, Rheumatology, Madrid, Spain, 5Hospital Universitario de La Princesa, IIS-Princesa, Madrid, Spain, 6Division of Rheumatology, Hospital Universitario de La Princesa, IIS-Princesa, Madrid, Spain

    Background/Purpose: Rheumatoid arthritis (RA) and osteoporosis (OP) have a complex interplay in terms of pathogenic mechanisms. In this regard, radiogrammetry (DXR) of the hand, a…
  • Abstract Number: 0532 • ACR Convergence 2022

    Women with Early Rheumatoid Arthritis Less Likely to Achieve Rapid and Sustainable Remission: Results from the Canadian Early Arthritis Cohort Study

    orit schieir1, Susan Bartlett2, Marie-France Valois1, Glen Hazlewood3, Louis Bessette4, Gilles Boire5, Carol Hitchon6, Edward Keystone7, Janet Pope8, diane tin9, Carter Thorne10, Vivian Bykerk11 and Canadian Early Arthritis Cohort (CATCH) Investigators12, 1McGill University, Montréal, QC, Canada, 2McGill University, Montreal, QC, Canada, 3University of Calgary, Calgary, AB, Canada, 4Centre de l'Ostoporose et de Rhumatologie de Québec, Québec, QC, Canada, 5Universite de Sherbrooke, Sherbrooke, QC, Canada, 6University of Manitoba, Winnipeg, MB, Canada, 7Keystone Consulting Enterprises Inc., Toronto, ON, Canada, 8University of Western Ontario, London, ON, Canada, 9Centre of Arthritis Excellence (CArE), Newmarket, ON, Canada, 10Southlake Regional Health Centre, Newmarket, ON, Canada, 11Hospital for Special Surgery, New York, NY, 12The Canadian Early Arthritis Cohort (CATCH), Bowmanville, ON, Canada

    Background/Purpose: Historical and established RA cohorts have reported sex disparities in remission outcomes favoring male patients. The objective of the present study was to compare…
  • Abstract Number: 1428 • ACR Convergence 2022

    Molecular and Clinical Profiling of Rheumatoid Arthritis Patients Predicts the Response to Rituximab

    Daniel Toro-Domínguez1, José Linares-Blanco1, Raúl López-Domínguez2, Pilar S. López-Garrido2, Georgina Galicia-Rosas1, Pedro Carmona-Sáez2 and Marta Alarcon-Riquelme1, 1Center for Genomics and Oncological Research (GENYO), Granada, Spain, 2University of Granada, Granada, Spain

    Background/Purpose: Rheumatoid arthritis (RA) is one of the most prevalent rheumatic diseases, mainly characterized by chronically painful, swollen joints that can severely impair physical function…
  • Abstract Number: 1390 • ACR Convergence 2021

    A 5% Increase in Interstitial Lung Disease at 1-Year Follow-up Is Associated with Long-Term ILD Progression in Systemic Sclerosis

    Alicia Hinze1, Shreyasee Amin1, Ashima Makol1, Robert Vassallo1, Cynthia Crowson2 and Brian Bartholmai1, 1Mayo Clinic, Rochester, MN, 2Mayo Clinic, Eyota, MN

    Background/Purpose: The clinical course of interstitial lung disease (ILD) in systemic sclerosis (SSc) is highly variable. Some patients experience a progressive decline in lung function…
  • Abstract Number: 1539 • ACR Convergence 2021

    High Disease Activity, as Assessed by RAPID3, Increases Risk of Hospitalization and Predicts Lower Chance of Recovery from COVID-19 in a Cohort of Tertiary Care Rheumatology Patients

    Matas Orentas1, Sonali Khandelwal2, Michael Grant2, Yanyu Zhang1, Najia Shakoor2 and Sobia Hassan1, 1RUMC, Chicago, IL, 2Rush University, Chicago, IL

    Background/Purpose: There is a need to understand which patients with rheumatologic diseases may be at highest risk for poor COVID-19 related outcomes so that both…
  • Abstract Number: 1630 • ACR Convergence 2021

    Multisystem Inflammatory Syndrome in Children: Clinical Characteristics and Predictors for Length of Hospitalization

    Lauren Covert1, Mara Becker2, Rebecca Sadun1 and Heather Van Mater1, 1Duke University, Durham, NC, 2Duke University Medical Center/Duke Clinical Research Institute, Chapel Hill, NC

    Background/Purpose: Multisystem Inflammatory Syndrome in Children (MIS-C) is a recently defined post-infectious phenomena associated with coronavirus disease 2019 (COVID-19). We assessed the demographics, clinical characteristics,…
  • Abstract Number: 0014 • ACR Convergence 2021

    Low Baseline Expression of Pyruvate Kinase and Succinate Dehydrogenase Genes in the Peripheral Blood of Rheumatoid Arthritis Patients Treated with Tofacitinib Is Associated with Clinical Remission at the End of Follow-up

    Elena Tchetina1, Azamat Satybaldyev2, Galina Markova1 and Alexander Lila2, 1Nasonova Research Institute of Rheumatology, Moscow, Russia, 2V.A. Nasonova Reseach Institute of Rheumatology, Moscow, Russia

    Background/Purpose: Rheumatoid arthritis (RA) is an autoimmune disease of unknown etiology, which is characterized by erosive arthritis and systemic inflammation. Tofacitinib (TFCN) is a Janus…
  • Abstract Number: 1775 • ACR Convergence 2021

    Isolated Axial versus Concomitant Peripheral Disease in Psoriatic Arthritis

    Timothy Kwok1, Mitchell Sutton2, Richard Cook3, Daniel Pereira4 and Dafna Gladman5, 1Toronto Western Hospital, University Health Network, University of Toronto, Toronto, ON, Canada, 2Centre for Prognosis Studies in the Rheumatic Diseases, Krembil Research Institute, Toronto Western Hospital, University Health Network, Toronto, ON, Canada, 3Department of Statistics and Actuarial Sciences, University of Waterloo, Waterloo, ON, Canada, 4University Health Network, Toronto, ON, Canada, 5Schroeder Arthritis Institute, Krembil Research Institute, Toronto Western Hospital, Toronto, ON, Canada

    Background/Purpose: Isolated axial involvement exists in 2 to 5% of all psoriatic arthritis (PsA) patients. However, it is currently unknown whether patients with isolated axial…
  • Abstract Number: 0083 • ACR Convergence 2021

    Cardiac Valve Surgery Outcomes in the Antiphospholipid Syndrome

    Tali Eviatar1, Stanley Niznik2, Nancy Agmon-Levin2 and Daphna Paran3, 1Tel Aviv Sourasky Medical Center, Givataim, Israel, 2Sheba Medical Center, Ramat Gan, Israel, 3Tel Aviv Sourasky Medical Center-Ichilov Hospital, Even Yehuda, Israel

    Background/Purpose: Cardiac valve involvement in the APS is prevalent, necessitating valve surgery in about 5% of the patients. Data regarding valve surgery outcomes in APS…
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