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Abstracts tagged "prognostic factors"

  • Abstract Number: 0865 • ACR Convergence 2026

    The endothelial activation and stress index (EASIX) predicts Clinical Progression to Antiphospholipid Syndrome in Antiphospholipid Antibody Carriers

    Rafael Galvez1, Rodrigo Cantera2, Maria Oviedo3, Maria abando3, Hector Cruz3, Raquel García3, Marina Herrero3, Jose Antonio Flores3, Irene Gorostidi3, Ariadna Garcia4, Ligia Gabrie5, Lucrecia Yanez3, Marcos Lopez6, Juan Jose Dominguez3, Luisa Gonzalez3, Belen Gonzalez3, Jose Luis Hernandez7 and Victor Manuel1 Affiliations: 1Department of Rheumatology, Hospital Universitario Marqués de Valdecilla; Immunopathology Group, IDIVAL. Department of Medicine and Psychiatry, University of Cantabria, Santander, Spain, Santander, Spain, 2Division of Hematology. Hospital Universitario de Navarra, Navarra, Spain, 3Division of Hematology. Hospital Universitario Marqués de Valdecilla-IDIVAL, Santander, Spain, Santander, Spain, 4Division of Hematology. Hospital Universitario Araba, Vitoria, Spain, Santander, Spain, 5Division of Rheumatology. Hospital Universitario Marqués de Valdecilla-IDIVAL, Santander, Spain, Santander, Spain, 6Marques de Valdecilla University Hospital-IDIVAL, Santander, Spain, 7Hospital Universitario Marqués de Valdecilla-IDIVAL, Immunopathology Group, Department of Internal Medicine and Psychiatry, University of Cantabria, Santander, Spain, Santander, Spain

    Background/Purpose: Endothelial dysfunction is a key mechanism in antiphospholipid syndrome (APS). However, biomarkers able to predict clinical progression in asymptomatic antiphospholipid antibody (aPL) carriers are…
  • Abstract Number: 1917 • ACR Convergence 2026

    Enhancing SLE Clinical Trial Efficiency With Prognostic Score Covariate Adjustment

    Roland Brown1, Eric Morand2, Wenting Cheng1, Jessica Kong1, Effie Pournara3 and Feng Gao1 Affiliations: 1Biogen, Cambridge, MA, USA, Cambridge, 2Centre for Inflammatory Disease, Monash University, Melbourne, Victoria, Australia, Melbourne, Victoria, Australia, 3Biogen, Baar, Zug, Switzerland, Zürich, Switzerland

    Background/Purpose: Adjusting for prognostic covariates or prognostic scores (PS) that capture baseline predictors of disease progression is a method supported by the regulatory agencies to…
  • Abstract Number: 0004 • ACR Convergence 2026

    Baseline and early longitudinal serum biomarkers in Polymyalgia Rheumatica: kinetics and associations with clinical course

    Pablo Muñoz-Martínez1, Elena Grau García2, Iago Alcántara Álvarez3, Belén Villanueva Mañes3, Miguel Simeó Vinaixa3, Andres Perez Hurtado3, patricia anton Enguidanos3, Belen diaz Mora3, Alba Maria Torrat Noves4, Daniel Ramos Castro3 and Jose Andres Roman Ivorra5 Affiliations: 11.Hospital Universitario y Politécnico La Fe; 2.Doctoral School Catholic University of Valencia San Vicente Mártir, Sagunto, Comunidad Valenciana, Spain, 2HUP La Fe, Valencia, Spain, 3Rheumatology Department. HUP La Fe, Valencia, Spain, 41.Rheumatology Department. HUP La Fe; 2.Doctoral School. Catholic University of Valencia San Vicente Mártir, Valencia, Spain, 5Hospital Universitari i Politècnic La Fe, Valencia, Spain

    Background/Purpose: Polymyalgia rheumatica (PMR) is characterized by systemic inflammation and rapid response to glucocorticoids (GC), but its biological heterogeneity and molecular effects of early treatment…
  • Abstract Number: 0894 • ACR Convergence 2026

    Risk Factors For Progression Of SI joint Structural Lesions On MRI In Early Axial SpA: 2-year Results From The SPondyloArthritis Caught Early Cohort

    Haluk Cinakli1, Liese de Bruin2, Gizem Ayan3, Ana Bento da Silva2, Manouk de Hooge4, Miranda van Lunteren2, Monique Reijnierse5, Marleen Van de Sande6, Inger Jorid Berg7, Roberta Ramonda8, Sofia Exarchou9, Floris van Gaalen10 and Sofia Ramiro11 Affiliations: 1Manisa City Hospital, Manisa, Manisa, Turkey, 2Leiden University Medical Center, Leiden, Netherlands, 3Division of Rheumatology, Department of Internal Medicine, Hacettepe University School of Medicine, Ankara, Turkey; Hacettepe University Vasculitis Research Center (HUVAC), Ankara, Turkey, Ankara, Turkey, 4Ghent University Hospital & Leiden University Medical Center, Leiden, Netherlands, 5Leiden University Medical Center, Department of Radiology, Leiden, Netherlands, 6University of Amsterdam, Amsterdam, Netherlands, 7Center for Treatment of Rheumatic and Musculoskeletal Diseases (REMEDY), Diakonhjemmet Hospital, Oslo, Nepal, 8Rheumatology Unit-DIMED-University of Padova ITALY, Padova, Italy, 9Lund University, Škarp, Sweden, 10Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 11Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands and Zuyderland Medical Center, Heerlen, Netherlands

    Background/Purpose: Structural lesions of the SI joints (SIJ) may be present in early axial SpA (axSpA), but data on risk factors for progression of such…
  • Abstract Number: 2129 • ACR Convergence 2026

    A deep learning model predicting the survival of Anti-neutrophil cytoplasmic antibody -associated vasculitis

    Xixi Shang Affiliations: 北京协和医院, Beijing, China (People's Republic)

    Background/Purpose: Objective: To comprehensively identify prognostic risk factors and predict survival outcomes in antineutrophil cytoplasmic antibody-associated vasculitis (AAV) utilizing deep learning techniques.Methods: Methods: We analyzed…
  • Abstract Number: 0181 • ACR Convergence 2026

    Neurological involvement and elevated erythrocyte sedimentation rate may predict relapse in the Takayasu Arteritis Early Inception Cohort

    Fatma Alibaz-Oner1, Sema Kaymaz-Tahra2, Aysegul Avcu3, Mustafa Ekici4, Buğu Bulat5, Fatih Albayrak6, HASAN KOCAAYAN7, Dilara Bulut-Gökten8, Pinar Akyuz Dagli9, Huseyin T E Ozer10, Burak Okyar11, Tuba Demirci-Yildirim12, Gökçe Kenar Artın13, Emel Oguz Kokoglu14, Ertuğrul Çağrı Bölek15, Hatice Vildan Polat16, Ragip Cetinkaya16, Simay Erdal Sayin16, Banu Ucmaklioglu16, Cemal Bes17, Nilufer Alpay-Kanitez18, AYTEN YAZICI19, Ayse Cefle20, Nursen Duzgun21, Ediz Dalkilic22, Sule Yavuz23, Lutfi Akyol24, Melike Kalfa25, Timucin Kasifoglu26, Gözde Yıldırım Çetin11, Mehmet Akif Ozturk27, Soner Senel14, Fatos Onen12, Suleyman Ozbek10, Ahmet Omma9, Ridvan Mercan8, Servet Akar28, Orhan Zengin29, Omer Karadag4 and Haner Direskeneli1 Affiliations: 1Division of Rheumatology, Department of Internal Medicine, School of Medicine, Marmara University, Istanbul, Istanbul, Turkey, 2Bahcesehir University Faculty of Medicine, Istanbul, Turkey, 3Marmara University School of Medicine, Department of Internal Medicine, Division of Rheumatology, Istanbul, Istanbul, Turkey, 4Hacettepe University School of Medicine, Department of Internal Medicine, Division of Rheumatology, Ankara, Turkey, 5Division of Rheumatology, Department of Internal Medicine, Hacettepe University School of Medicine, Ankara, Turkey; Hacettepe University Vasculitis Research Center (HUVAC), Ankara, Turkey, Ankara, Turkey, 6Gaziantep University School of Medicine, Department of Internal Medicine, Division of Rheumatology, Gaziantep, Turkey, 7Izmir Katip Celebi University School of Medicine, Department of Internal Medicine, Division of Rheumatology Izmir Ataturk Education and Reseach Hospital, Izmir, Izmir, Turkey, 8Tekirdağ Namık Kemal University School of Medicine, Department of Internal Medicine, Division of Rheumatology, Tekirdağ, Turkey, 9Ankara City Hospital, Rheumatology Clinic, Ankara, Turkey, 10Çukurova University School of Medicine, Department of Internal Medicine, Division of Rheumatology, Adana, Turkey, 11Kahramanmaraş Sütçü İmam University School of Medicine, Department of Internal Medicine, Division of Rheumatology, Kahramanmaraş, Turkey, 12Dokuz Eylül University School of Medicine, Department of Internal Medicine, Division of Rheumatology, Izmir, Turkey, 13Dokuz Eylul University School of Medicine, Izmir, Izmir, Turkey, 14Erciyes University School of Medicine, Department of Internal Medicine, Division of Rheumatology, Kayseri, Turkey, 15Division of Rheumatology, Department of Pediatrics, Hacettepe University School of Medicine, Ankara, Turkey, Ankara, Turkey, 16Marmara University School of Medicine, Istanbul, Turkey, 17Division of Rheumatology, Department of Internal Medicine, Başaksehir Cam ve Sakura City Hospital, Istanbul, Istanbul, Turkey, 18Division of Rheumatology, Department of Internal Medicine, School of Medicine, Koc University, Istanbul, Istanbul, Turkey, 19Division of Rheumatology, Department of Internal Medicine, School of Medicine, Kocaeli University, Istanbul, Turkey, 20Division of Rheumatology, Department of Internal Medicine, School of Medicine, Kocaeli University, Kocaeli, Turkey, 21Ankara University School of Medicine, Department of Internal Medicine, Division of Rheumatology, Ankara, Turkey, 22Division of Rheumatology, Department of Internal Medicine, Faculty of Medicine, Uludag University, Bursa, Turkey, 23Istanbul Bilim University School of Medicine, Department of Internal Medicine, Rheumatology Clinic, Istanbul, 24Ondokuz Mayıs University School of Medicine, Internal Medicine, Division of Rheumatology,, Samsun, Turkey, 25Muğla Sıtkı Koçman University School of Medicine, Department of Internal Medicine, Division of Rheumatology, Muğla, 26Osmangazi Uni., Eskisehir, Turkey, 27Gazi University School of Medicine, Department of Internal Medicine, Division of Rheumatology, Ankara, Turkey, 28Izmir Katip Celebi University School of Medicine, Izmir, Turkey, 29Division of Rheumatology, Department of Internal Medicine, Faculty of Medicine, Gaziantep University, Gaziantep, Turkey

    Background/Purpose: Takayasu arteritis (TAK) is a rare large-vessel vasculitis for which long-term prognostic data remain limited and are mostly derived from retrospective studies. This study…
  • Abstract Number: 0954 • ACR Convergence 2026

    Serial Quantitative Changes in Anti-Scl-70 Autoantibodies Are Associated with Lung Function Decline in Systemic Sclerosis

    Eric Robbins1, Julio Huapaya1, Xin Tian2, Shijinqiu Gao3, Harshkumar Patel4, Peter Burbelo5, Tracy Frech6, Jessica Gordon7, Maureen Mayes8, Lorinda Chung9, Ankoor Shah10, Flavia Castelino11, Brian Skaug12, Peter A. Merkel13, Nora Sandorfi13, Faye Hant14, Ashima Makol15, Carrie Richardson16, Laura Hummers17, Dinesh Khanna18, Zsuzsanna McMahan19, Jerry Molitor20, Melissa Griffith21, Duncan Moore22, Kimberly Lakin7, Elizabeth Volkmann23, Ami Shah24, Yiming Luo25, Carleigh Zahn26, Sonali J Bracken27, Julie Paik28, Andreea Bujor29, Erica Mulcaire-Jones26, Dorota Lebiedz-Odrobina30, Neha Gupta4, Ching (Katharine) Chung31, Luke Evnin32, Elana Bernstein25, Monica Harding33, John VanBuren33, Shervin Assassi34, Anthony Suffredini4 and Virginia Steen35 Affiliations: 1Critical Care Medicine and Pulmonary Branch; National Heart, Lung, and Blood Institute; National Institutes of Health, Bethesda, MD, 2Office of Biostatistics Research; National Heart, Lung, and Blood Institute; National Institutes of Health, Bethesda, MD, 3Office of Biostatistics Research; National Heart, Lung, and Blood Institute; National Institutes of Health, Bethesda, 4Critical Care Medicine and Pulmonary Branch; National Heart, Lung, and Blood Institute; National Institutes of Health, Bethesda, 5National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, 6Vanderbilt Health, Nashville, TN, 7Hospital for Special Surgery, New York, NY, 8UT Health Houston Division of Rheumatology, Houston, TX, 9Stanford University School of Medicine, Stanford, CA, 10Duke University, Durham, NC, 11Massachusetts General Hospital, Boston, MA, 12UTHealth Houston Division of Rheumatology, Houston, TX, 13University of Pennsylvania, Philadelphia, PA, 14Medical University of South Carolina, Charleston, SC, 15Mayo Clinic, Rochester, MN, Rochester, MN, 16Northwestern University, Chicago, IL, 17Johns Hopkins Rheumatology, Baltimore, MD, 18Division of Rheumatology, Department of Internal Medicine, University of Michigan Scleroderma Program, Ann Arbor, MI, 19UT Health Houston, Houston, TX, 20University of Minnesota, Minneapolis, MN, 21University of Colorado, Aurora, CO, 22Northwestern Memorial Hospital, Wilmette, IL, 23University of California, Los Angeles, Los Angeles, CA, 24Johns Hopkins Rheumatology, Ellicott City, MD, 25Columbia University, New York, NY, 26University of Michigan, Ann Arbor, MI, 27Duke University Medical Center, Durham, NC, USA, Durham, NC, 28Johns Hopkins University, Baltimore, MD, 29Boston University, Boston, MA, 30University of Utah, Cottonwood Heights, UT, 31National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, 32Scleroderma Research Foundation, Brisbane, CA, 33Division of Pediatric Critical Care, Department of Pediatrics, University of Utah, Salt Lake City, 34Division of Rheumatology, UTHealth Houston, Houston, TX, 35Georgetown University School of Medicine, Washington, DC

    Background/Purpose: Anti-topoisomerase I autoantibodies (anti-Scl-70) are associated with systemic sclerosis-associated interstitial lung disease (SSc-ILD), but prior prognostic studies have largely focused on cross-sectional autoantibody status.…
  • Abstract Number: 2172 • ACR Convergence 2026

    Forced Vital Capacity Trajectories During the Treatment-Naïve Period in Systemic Sclerosis: A 20-Year Ambispective Cohort Study

    HEE WON CHO1, YunHee Choi2, Jun Won Park3, Jin Kyun Park4 and Eun Bong Lee5 Affiliations: 1Seoul National University, Jongno District, Seoul, Republic of Korea, 2Seoul National University, Seoul, Republic of Korea, 3Seoul National University Hospital, Seoul, South Korea, 4Seoul National University College of Medicine, Seoul, Republic of Korea, 5Seoul National University Hospital, Seoul, Republic of Korea

    Background/Purpose: Systemic sclerosis (SSc) is a rare autoimmune disease in which pulmonary involvement is a major cause of mortality. Despite its clinical importance, the natural…
  • Abstract Number: 0194 • ACR Convergence 2026

    Baseline ‘aggregate index of systemic inflammation’ reflects current high activity and predicts all-cause mortality in patients with antineutrophil cytoplasmic antibody-associated vasculitis

    Juyoung Yoo1, Jihye Chung2 and Sang-Won Lee3 Affiliations: 1Yonseidael Clinic, Seoul, Republic of Korea, 2Severance hospital, Seoul, Republic of Korea, 3Yonsei University College of Medicine, Seoul, South Korea

    Background/Purpose: The aggregate index of systemic inflammation (AISI) was recently introduced as a prognostic index in various inflammatory diseases. This study investigated the clinical utility…
  • Abstract Number: 1019 • ACR Convergence 2026

    Genetic predisposition to Systemic Lupus Erythematosus increases Decoy receptor 3 levels, which associate with disease severity and progression

    Sarah Reid, Ioanna Giannakou, Joachim Burman, Lars Rönnblom, Maija-Leena Eloranta and Dag Leonard Affiliations: Department of Medical Sciences, Uppsala University, Uppsala, Sweden

    Background/Purpose: Systemic Lupus Erythematosus (SLE) is a heterogeneous autoimmune disease characterized by loss of tolerance to self-antigens, immune complex formation and activation of the interferon…
  • Abstract Number: 2175 • ACR Convergence 2026

    Initial Presentation Of Systemic Sclerosis (SSc) Defines Clinically Meaningful SSc Phenotypes

    Liu Liu1, Sophie Krijger1, Katie van der Wouden1, Lianne Kwant1, Yvo Santema1, Tom Huizinga1, Jacopo Ciaffi2, Anne Schouffoer3 and Jeska de Vries1 Affiliations: 1Leiden University Medical Center, Leiden, Netherlands, 2IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy, 3Hagaziekenhuis, the Hague, Netherlands

    Background/Purpose: To enhance early recognition of systemic sclerosis (SSc), the Very Early Diagnosis of Systemic Sclerosis (VEDOSS) criteria were developed to identify patients with Raynaud…
  • Abstract Number: 0220 • ACR Convergence 2026

    High-Intensity Immunosuppression with Autologous Stem Cell Transplantation Versus Modern Standard Care in Poor-Prognosis Diffuse Cutaneous Systemic Sclerosis: A Propensity-Matched Study

    Lucas Khellaf1, Rémi Khellaf2, Pierre Pinson3, Yannick Allanore4, Zahir Amoura5, Jerome Avouac6, Tiphaine Goulenok7, Bertrand Dunogue8, Anuxcy Kanagaratnam9, Sebastien riviere10, Guillaume Buissone11, Robin Dhote12, Jean-Emmanuel kahn13, Olivier Lidove14, MEKINIAN Arsene15, Didier Bouscary16, Luc Mouthon8 and Benjamin Chaigne8 Affiliations: 1Cochin university Hospital, Paris, France, 2INRIA, PreMeDICaL Team, Montpellier University, Montpellier, France;, Paris, France, 3Clinical Research Unit, Cochin Hospital, AP-HP, University Paris Cité, Paris;, Paris, France, 4Université Paris Cité, Paris, France, 5Service de médecine interne 2, centre de référence des maladies auto-immunes et auto-inflammatoires systémiques rares de l'adulte d'Ile-de-France, Centre et Martinique, Groupement hospitalier Pitié-Salpêtrière, Institut E3M, AP-HP,, Paris, France, 6National Referral Center for Rare Systemic Autoimmune Diseases, Cochin Hospital, AP-HP, Paris, France, Paris (75014), France, 7Department of Internal Medicine, Bichat-Claude Bernard Hospital, AP-HP, Paris, France, 8Internal Medicine Department, National Referral Center for Rare Systemic Autoimmune and Autoinflammatory Diseases of Ile de France, Cochin Hospital, APHP, Paris Cité University, Paris, France, 9Internal medicine department, Cochin Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris, France;, paris, 10Internal medicine department, AP-HP Sant-Antoine Hospital, Paris;, paris, France, 11Internal medicine department, AP-HP Antoine Béclère Hospital, Paris;, Paris, France, 12Internal medicine department, Cochin Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris, France;, Paris, France, 13CHU Ambroise Paré, Suresnes Cedex, 14Internal medicine and Rheumatology department, Diaconesses-Croix Saint Simon Hospital Group, Paris, France., Paris, France, 15Internal Medicine Department, Saint Antoine Hospital, APHP, Sorbonne University, Paris, France, 16Hematology department, Cochin Hospital, AP-HP, Paris., Paris, France

    Background/Purpose: The 2023 EULAR update recommends high-intensity immunosuppression followed by autologous hematopoietic stem-cell transplantation (HI-IS/HSCT) for selected patients with poor-prognosis early diffuse cutaneous systemic sclerosis…
  • Abstract Number: 1134 • ACR Convergence 2026

    High Visual Burden and Distinct Cranial Phenotype in an Irish Giant Cell Arteritis Cohort

    Danielle Molloy1, Colm Kirby2, Sharon Cowley3, Patricia Harkins4, Richard Conway5, Grainne Murphy6 and David Kane7 Affiliations: 1Tallaght University Hospital, Tallaght, Dublin, Ireland, 2Tallaght University Hospital, Dublin, Ireland, 3Tallaght University Hospital, Dublin, Dublin, Dublin, Ireland, 4Trinity College Dublin, Dublin 8, Dublin, Ireland, 5Trinity College Dublin, Dublin, Ireland, 6Cork University Hospital, Cork, Ireland, 7Tallaght University Hospital & Trinity College Dublin, D24, Dublin, Ireland

    Background/Purpose: Giant cell arteritis (GCA) demonstrates heterogenous clinical phenotypes with variable cranial, systemic and visual involvement. Visual loss remains the most feared complication of GCA…
  • Abstract Number: 2176 • ACR Convergence 2026

    Neutrophil-to-Lymphocyte Ratio Is Associated With Progression From VEDOSS to Definite Systemic Sclerosis

    Francesco Bonomi1, Cristiano Barbetta2, Martina Iacubino3, Veronica De Silvestri4, Silvia Peretti5, Lorenzo Beretta6, Chiara Bellocchi7 and Silvia Bellando Randone8 Affiliations: 1Azienda Ospedaliera Universitaria Careggi, Florence, Italy, 2Department of Experimental and Clinical Medicine, Division of Rheumatology, Florence, Italy, 3Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico di Milano, Milan, Italy, 4University Hospital Careggi, Florence, Italy, 5Department of Internal Medicine, Careggi University Hospital, Florence, Italy, 6Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico di MIlano, Milan, Milan, Italy, 74. Department of Clinical Sciences and Community Health, University of Milan, Milano, Italy, 8Department of Experimental and Clinical Medicine, University of Florence, Rheumatology Division, Scleroderma Unit. AOU Careggi, Florence, Italy, Florence, Italy

    Background/Purpose: Risk stratification in VEDOSS remains challenging, as only a proportion of patientsprogress to definite systemic sclerosis (SSc) during follow-up. Current predictors are mainlyclinical, serological…
  • Abstract Number: 0234 • ACR Convergence 2026

    Evidence-based predictors of systemic sclerosis-interstitial lung disease patients: the EUSTAR-PPFstudy (CP number 148)

    Corrado Campochiaro1, Donato Tiano2, Denis Morgin3, Daniele Celada4, Simone Barbieri4, Claudia Iannone1, Giacomo De Luca1, Patricia Carreira5, Jeska de Vries6, Gabor Kumanovics7, Radim Bečvář8, Oliver Distler9, Alexandra Balbir-Gurman10, Enrico Selvi11, Alberto Cauli12, Simona Rednic13, Francesco Del Galdo14, Marco Di Battista15, Jelena Colic16, Carlo Tacchetti4, Masataka Kuwana17, Marie-Elise Truchetet18, Marco Matucci-Cerinic19, Michele Iudici3 and Yannick Allanore20 Affiliations: 1Unit of Immunology, Rheumatology, Allergy and Rare Diseases (UnIRAR), IRCCS San Raffaele Hospital, Vita-Salute San Raffaele University, Milan, Italy, 2S-RACE (San-Raffaele Ai CEnter), Vita-Salute San Raffaele University, Milan, Italy, 3University of Geneva, Rheumatology, Geneve, Switzerland, 4S-RACE (San-Raffaele Ai CEnter), University Vita-Salute San Raffaele, Milan, Italy, 5Hospital Universitario 12 de Octubre, Madrid, Spain, 6Leiden University Medical Center, Leiden, Netherlands, 7Department of Rheumatology, Immunology and Musculoskeletal Rehabilitation, Medical School, University of Pécs, Hungary, Pécs, Baranya, Hungary, 8Institute of Rheumatology, Prague, Czechia; First Faculty of Medicine, Charles University, Prague, Czechia, Prague, Czech Republic, 9Department of Rheumatology, University Hospital, Zurich, Switzerland, Zurich, Switzerland, 10Rheumatology Institute, Rambam Health Care Campus and The Rappaport Faculty of |Medicine, Technion, Haifa, Israel, 11Department of Medical Sciences, Surgery and Neurosciences, University of Siena, Rheumatology, Siena, Italy, 12AOU and University Hospital Of Cagliari, Rheumatology, Cagliari, Cagliari, Italy, 13University of Medicine and Pharmay, Cluj-Napoca, Rheumatology, Cluj-Napoca, Romania, 14University of Leeds, Leeds, United Kingdom, 15University of Pisa, Rheumatology, Pisa, Italy, 16Rheumatology, University of Belgrade Faculty of Medicine, Beograd, Serbia, Rheumatology, University of Belgrade Faculty of Medicine, Beograd, Serbia, Serbia, 17Nippon Medical School Graduate School of Medicine, Tokyo, Japan, 18Bordeaux University Hospital, Bordeaux, France, 19University San Raffaele Milano, Milano, Milan, Italy, 20Rheumatology Department, Cochin Hospital, Université Paris Cité, Paris, France

    Background/Purpose: Interstitial lung disease(ILD) is the leading cause of mortality in systemic sclerosis(SSc). Identifying patients at risk of progression remains a major clinical challenge.Methods: SSc-ILD…
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