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Abstracts tagged "Polymyositis/dermatomyositis (PM/DM)"

  • Abstract Number: 398 • 2019 ACR/ARP Annual Meeting

    Seasonal Variation in Idiopathic Inflammatory Myopathies Incidence and Presentation: A Retrospective Study in Beijing and Hong Kong

    Ho SO 1, Yawen SHEN2, Victor Tak Lung WONG 1, Roy HO 1 and Xin LU 2, 1Kwong Wah Hospital, Kowloon, Hong Kong, 2China Japan Friendship Hospital, BeiJing, China (People's Republic)

    Background/Purpose: Seasonal patterns of disease onset and severity in idiopathic inflammatory myopathies (IIMs) as a whole are conflicting. In recent years, over 10 myositis-specific antibodies…
  • Abstract Number: 407 • 2019 ACR/ARP Annual Meeting

    Utility of Anti-SSA/SSB Assay and Anti-Ro 52 Antibody Assay in Routine Clinical Practice for Risk Assessment of Patients with Idiopathic Inflammatory Myositis

    Galina Marder 1, Sonali Narain2, Maria-Louise Barilla-Labarca 1 and Ana Valle 1, 1Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY, 2Northwell Health, Great Neck, Long Island, NY

    Background/Purpose: Idiopathic inflammatory myopathies (IIM) are chronic autoimmune diseases affecting multiple organ systems and associated with a diverse autoantibody profile. Anti-SSA/SSB are the most frequent…
  • Abstract Number: 1275 • 2019 ACR/ARP Annual Meeting

    Spectrum of Organ Involvement in Idiopathic Inflammatory Myopathies, Frequency of Comorbidities, and Relationship to Anti-SSA/SSB Positivity

    Ana Valle1, Galina Marder 1, Maria-Louise Barilla-Labarca 1 and Sonali Narain 2, 1Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY, 2Northwell Health, Great Neck, Long Island, NY

    Background/Purpose: Idiopathic inflammatory myopathies (IIM) are chronic autoimmune diseases with systemic features and multiple  comorbidities. Of the myositis associated antibodies seen in this population, anti-SSA/SSB…
  • Abstract Number: 1293 • 2019 ACR/ARP Annual Meeting

    Multiple Subpopulations of Lymphocytes Were Absolutely Decreased in Dermatomyositis/polymyositis Patients and Restored by Low-dose IL-2

    Jia Wang 1, He-hua Sun 1, Sheng-xiao Zhang2, Jia-qian Zhang 1, Jiang Bai 3, Jing Luo 3, Cai-hong Wang 4, Chong Gao 5 and Xiao-feng Li 1, 1The Second Hospital of Shanxi Medical University, Taiyuan, China (People's Republic), 2The Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, China (People's Republic), 3Shanxi Medical University, Taiyuan, China (People's Republic), 4The Second Hospital of Shanxi Medical University, Tai Yuan, China (People's Republic), 5Brigham and Women’s Hospital, Harvard Medical School, Boston

    Background/Purpose: Dermatomyositis (DM) and polymyositis (PM) are rare chronicinflammatory disorders with significant associated morbidityand mortality despite treatment, characterized by subacute onset of proximal muscle weakness,…
  • Abstract Number: 1870 • 2019 ACR/ARP Annual Meeting

    NMR-Based Serum, Urine and Muscle Metabolomics in Inflammatory Myositis for Diagnosis and Activity Assessment: Serum Metabolomics Can Differentiate Active from Inactive Myositis

    Latika Gupta1, Dinesh Kumar 2, Umesh Kumar 3, Anupam Guleria 2, Abhishek Zanwar 4, Ritu Raj 5 and Ramnath Misra 1, 1Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Lucknow, Uttar Pradesh, India, 2Centre for Biomedical Research, Sanjay Gandhi Post Graduate Institute of Medical Science, Lucknow, Uttar Pradesh, India, 3Centre of Biomedical Research SGPGIMS, Raibareli Road, Lucknow-226014, India, Lucknow, Uttar Pradesh, India, 4Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India, 5Centre of Biomedical Research, Lucknow, Uttar Pradesh, India

    Background/Purpose: Differentiating smouldering disease activity from weakness due to fatty replacement of atrophied muscle can often be a challenge in Idiopathic Inflammatory Myositis (IIM). There…
  • Abstract Number: 397 • 2019 ACR/ARP Annual Meeting

    Clinical Features of Polymyositis and Dermatomyositis Patients with Severe Dysphagia

    Nozomi Takasugi1, Yutaro Hayashi 1, Keisuke Izumi 2, Satoshi Hama 3, Misako Konishi 1, Mari Ushikubo 1, Yutaka Okano 1 and Hisaji Ohshima 1, 1National Tokyo Medical Center, tokyo, Japan, 2Division of Rheumatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan, 3tokyo medical center, tokyo, Japan

    Background/Purpose: Polymyositis (PM) and dermatomyositis (DM) are autoimmune inflammatory diseases characterized by proximal myositis. Dysphagia has been reported to develop in 35 to 62% of…
  • Abstract Number: 1210 • 2018 ACR/ARHP Annual Meeting

    Sonographic Appearance of Inflammatory Myopathies: Increased Muscle Echointensity and Qualitative Changes

    Kristofoor Leeuwenberg1, Lisa Christopher-Stine1, Clifton O. Bingham III2, Julie J. Paik2, Eleni Tiniakou3, Seth Billings4, Philippe Burlina4 and Jemima Albayda5, 1Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, 2Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, 3Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, 4Johns Hopkins University Applied Physics Lab, Laurel, MD, 5Johns Hopkins University School of Medicine, Baltimore, MD

    Background/Purpose: The use of ultrasound in the assessment of muscle conditions has grown over the years. Various myopathies have shown an increase in echo intensity…
  • Abstract Number: 277 • 2016 ACR/ARHP Annual Meeting

    Abnormal Composition of Circulating T and B Cells in Patients with Polymyositis and Dermatomyositis Is More Biased in Those with Interstitial Lung Diseases

    Hirokazu Sasaki, Akito Takamura, Kimito Kawahata and Hitoshi Kohsaka, Department of Rheumatology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo, Japan

    Background/Purpose: Polymyositis (PM) and dermatomyositis (DM) are systemic inflammatory myopathies. They sometimes accompany interstitial lung disease (ILD), which can lead often to fatal outcome. For…
  • Abstract Number: 288 • 2015 ACR/ARHP Annual Meeting

    Myositis Associated Interstitial Lung Disease: Clinical Predictors of Failure to Conventional Treatment and Their Response to Tacrolimus

    Niharika Sharma1, Anisha Dua1, Michael Putman2, Rekha Vij3 and Mary Strek3, 1Rheumatology, The University of Chicago, Chicago, IL, 2Internal Medicine, The University of Chicago, Chicago, IL, 3Pulmonology, The University of Chicago, Chicago, IL

    Background/Purpose: Interstitial lung disease (ILD) frequently complicates Polymyositis (PM) and Dermatomyositis (DM) and accounts for significant morbidity and mortality in affected patients.  Patients with Myositis…
  • Abstract Number: 948 • 2015 ACR/ARHP Annual Meeting

    Autoimmune Myopathies: Effects of Intravenous Immunoglobulin Therapy on Muscle Strength and Predictors of Response

    Arash Lahoutiharahdashti1, Iago Pinal-Fernandez2, Jemima Albayda1, Julie J. Paik3, Sonye K. Danoff4, Andrew Mammen5 and Lisa Christopher-Stine6, 1Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, 2Autoimmune Systemic Diseases Unit, Vall D’Hebron University Hospital, Universitat Autònoma de Barcelona, Barcelona, Spain, 3Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, 4Medicine/Pulmonary, Johns Hopkins School of Medicine, Baltimore, MD, 5Center Tower Ste 5300, Johns Hopkins University School of Medicine, Baltimore, MD, 6Ste 4100 Rm 409, Johns Hopkins University School of Medicine, Baltimore, MD

    Background/Purpose: There is a variable response rate to Intravenous immunoglobulin (IVIG) in patients with autoimmune myopathies. The aim of this study was to determine whether…
  • Abstract Number: 2222 • 2014 ACR/ARHP Annual Meeting

    Predictors of Myositis Treatments Received and Associated Treatment Responses in Myovision, a National Myositis Patient Registry

    Abdullah Faiq1, Payam Noroozi Farhadi1, Jesse Wilkerson2, Nastaran Bayat1, Anna Jansen3, Kathryn Rose4, Lukasz Itert5, Anne Johnson6, Christine Parks7, Edward H. Giannini8, Hermine I. Brunner9, Bob Goldberg10, Richard Morris4, Frederick W. Miller1 and Lisa G. Rider1, 1Environmental Autoimmunity Group, NIEHS, NIH, Bethesda, MD, 2Social and Scientific Systems, Inc., Research Triangle Park, NC, 3Environmental Autoimmunity Group, NIEHS / EAG, Bethesda, MD, 4Social and Scientific Systems, Inc., Durham, NC, 5Division of Pediatric Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 6Pediatric Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 7Epidemiology Branch, NIEHS, NIH, Research Triangle Park, NC, 8Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 9PRCSG, Cincinnati, OH, 10The Myositis Association, Alexandria, VA

    Background/Purpose: Little is known about medications received for myositis and patients’ responses to therapies. We present information on self-reported myositis therapy use and responses from…
  • Abstract Number: 1261 • 2014 ACR/ARHP Annual Meeting

    Pulmonary Arterial Hypertension in Patients with Anti-PM-Scl Antibody

    Hiromichi Tamaki1, Colin O'Rourke2 and Soumya Chatterjee3, 1Rheumatology, Cleveland Clinic, Cleveland, OH, 2Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH, 3Rheumatic and Immunologic Ds, Cleveland Clinic, Cleveland, OH

    Background/Purpose: Patients with anti-PM-Scl antibody (PM-Scl) can present with several different phenotypes: polymyositis (PM), dermatomyositis (DM), systemic sclerosis (SSc), scleromyositis, or sclero-dermatomyositis. Pulmonary arterial hypertension…
  • Abstract Number: 221 • 2012 ACR/ARHP Annual Meeting

    Expanding the Clinical and Serological Spectrum of MDA5-Associated Dermatomyositis

    John C. Hall1, Livia Casciola Rosen1, Sonye K. Danoff2, Lesly-Anne Samedy3 and Lisa Christopher-Stine4, 1Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, 2Medicine/Pulmonary, Johns Hopkins University, Baltimore, MD, 3Division of Rheumatology, Johns Hopkins University, Baltimore, MD, 4Medicine and Neurology, Johns Hopkins University, Baltimore, MD

    Background/Purpose: Dermatomyositis (DM) is a heterogeneous systemic disease with specific autoantibodies (Abs) which correlate with unique clinical phenotypes.  Melanoma differentiation-associated gene 5 (MDA5) Abs have…
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