ACR Meeting Abstracts

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Abstracts tagged "Pediatric rheumatology"

  • Abstract Number: 1932 • ACR Convergence 2024

    Effects of Clinical Decision Support on Transition Readiness Assessment in Pediatric Rheumatology

    Chrisana Pokorny1 and Bethany Marston2, 1University of Rochester, Webster, NY, 2University of Rochester, Rochester, NY

    Background/Purpose: Pediatric to adult transition is often challenging among young adults with rheumatic diseases. Structured transition programs can improve adherence to care, quality of life,…
  • Abstract Number: 2189 • ACR Convergence 2024

    Migratory Arthritis in Children: What Besides Rheumatic Fever?

    bar goldberg1, Gil Amarilyo2, oded Scheuerman1, tarek Zuabi3, alina Guz1, Maayan Ravia1 and yoel Levinsky1, 1schneider medical center, petah tikva, Israel, 2Faculty of Medicine, Tel Aviv University, Tel Aviv; Pediatric Rheumatology Unit, Schneider Children's Medical Center of Israel, Petach Tikva, Israel, Kibbutz Maggal, HaMerkaz, Israel, 3schneider medical center, petah tikva

    Background/Purpose: Migratory Arthritis, a not uncommon presentation in pediatrics, is classically associated with rheumatic fever (RF), although can be the first presentation of other medical…
  • Abstract Number: 2207 • ACR Convergence 2024

    Improvement Across Physician and Patient Reported Outcome Measures over a 24 Months-time Period in the Juvenile Systemic Scleroderma Inception Cohort

    Ivan Foeldvari1, Jens Klotsche2, Ozgur Kasapcopur3, Amra Adrovic4, Kathryn Torok5, Maria Teresa Terreri6, Ana Sakamoto7, Jordi Anton8, Brian Feldman9, Raju Khubchandani10, Tadey Avcin11, Sindhu R. Johnson12, Mikhail Kostik13, Edoardo Marrani14, Flavio Sztajnbok15, Maria Katsicas16, Dana Nemcova17, Maria Jose Santos18, Simone Appenzeller19, Cristina Battagliotti20, Lillemor Berntson21, Jürgen Brunner22, Liora Harel23, Gerd Horneff24, Tilmann Kallinich25, Kirsten Minden2, Farzana Nuruzzaman26, Anjali Patwardhan27, Dieneke Schonenberg-Meinema28 and Nicola Helmus29, 1Hamburger Zentrum für Kinder- und Jugendrheumatologie, Hamburg, Germany, 2German Rheumatism Research Center, Berlin, Germany, 3Istanbul University-Cerrahpasa, Cerrahpasa Medical School, istanbul, Turkey, 4Cerrahpasa Medical School, Istanbul, Turkey, 5Division of Rheumatology, Scleroderma Center, Department of Pediatrics, UPMC Children’s Hospital of Pittsburgh, Pittsburgh, PA, USA, Pittsburgh, PA, 6UNIFESP, São Paulo, SP, Brazil, 7Federal University of São Paulo (UNIFESP), São Paulo, SP, Brazil, 8Hospital Sant Joan de Déu. Universitat de Barcelona, Esplugues de Llobregat (Barcelona), Spain, 9Division of Rheumatology, The Hospital for Sick Children; Departments of Pediatrics and Medicine, Faculty of Medicine; The Institute for Health Policy, Management and Evaluation, Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada, 10SRCC Childrens Hospital, Mumbai, India, 11University Children's Hospital University Medical Center Ljubljana, Ljubljana, Slovenia, 12University of Toronto, Toronto, Canada, 13Saint-Petersburg State Pediatric Medical University, Saint Petersburg, Russia, 14University of Florence, Firenze, Florence, Italy, 15UFRJ/UERJ, SAO PAULO, Brazil, 16Hospital Garrahan, Buenos Aires, Argentina, 17MD, Prague, Czech Republic, 18Hospital Garcia de Orta and Centro Académico de Medicina de Lisboa, Lisboa, Portugal, 19Unicamp, Campinas, SP, Brazil, 20Hospital de Niños Dr Orlando Alassia, Santa Fe, Argentina, 21Dept. of Women’s and Children’s Health, Uppsala University, Uppsala, Sweden, 22Medical University Innsbruck; Department of Pediatrics, Pediatric Rheumatology, Innsbruck, Austria, 23Faculty of Medicine, Tel Aviv University, Tel Aviv; Pediatric Rheumatology Unit, Schneider Children's Medical Center of Israel, Petach Tikva, Israel, Petach Tikva, HaMerkaz, Israel, 24Asklepios Klinik Sankt Augustin GmbH, Sankt Augustin, Germany, 25Charite, Berlin, Germany, 26Stony Brook Children's Hospital, Stony Brook, NY, 27University of Missouri-Columbia, Department of Child Health, 404 N Keene Street, Columbia MO 65210, Columbia, 28Emma Children’s Hospital, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, Netherlands, 29Hamburg Centre for Pediatric and Adolescence Rheumatology, Hamburg, Germany

    Background/Purpose: Juvenile systemic sclerosis (jSSc) is an orphan disease with a prevalence of 3 in 1 000 000 children. The Juvenile Systemic Scleroderma Inception cohort…
  • Abstract Number: 2624 • ACR Convergence 2024

    Measuring Clinically Inactive Disease at One Year in Patients with Juvenile Dermatomyositis (JDM) in the Childhood Arthritis and Rheumatology Research Alliance (CARRA) Registry

    Jessica Neely1, Peter Shrader2, Stacey Tarvin3, Kaveh Ardalan4, Susan Shenoi5, Adam Huber6, Susan Kim7 and Hanna Kim8, and for the CARRA Registry Investigators, 1UCSF, San Francisco, CA, 2Duke Clinical Research Institute, Durham, NC, 3Indiana University School of Medicine, Indianapolis, IN, 4Duke University School of Medicine, Durham, NC, 5Seattle Children's Hospital and Research Center, Mercer Island, WA, WA, 6IWK Health Centre, Halifax, NS, Canada, 7University of California, San Francisco, CA, 8National Institute of Arthritis Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD

    Background/Purpose: While remission off medication is the goal in JDM, timely achievement of clinically inactive disease (CID) is an important interim outcome.  Data from the…
  • Abstract Number: 0186 • ACR Convergence 2024

    Development of a Novel Dried Blood Spot Method to Improve Capacity for ANA Testing in Lower-Resource Settings

    Ekemini Ogbu1, Stela Florea2, Donna Diorio2, Somak Roy2, Dhriti Sharma2, Michael Henrickson2, Patricia Vega-Fernandez2, Angela Migowa3, Sarangarajan Ranganathan2 and hermine brunner1, 1Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH, 2Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 3AGA KHAN UNIVERSITY, Nairobi, Kenya

    Background/Purpose: Timely diagnosis of children and young adults with rheumatologic disorders remains a global challenge especially in lower-resource settings. There is limited access to diagnostic…
  • Abstract Number: 0397 • ACR Convergence 2024

    Trends in New Use of Disease-Modifying Antirheumatic Drugs in Juvenile Idiopathic Arthritis Among Commercially Insured Children in the United States from 2001-2022

    Priyanka Yalamanchili1, Lydia Lee2, Greta Bushnell3, Melissa Mannion4, Chintan Dave5 and Daniel B. Horton6, 1Center for Pharmacoepidemiology and Treatment Science, Institute for Health, Health Care Policy, and Aging Research, Morris Plains, NJ, 2Center for Health Outcomes, Policy & Economics, Rutgers Ernest Mario School of Pharmacy and Rutgers School of Public Health, Piscataway, NJ, 3Center for Pharmacoepidemiology and Treatment Science, Institute for Health, Health Care Policy, and Aging Research; Department of Biostatistics and Epidemiology, Rutgers School of Public Health, New Brunswick, NJ, 4University of Alabama at Birmingham, Birmingham, AL, 5Center for Pharmacoepidemiology and Treatment Science, Institute for Health, Health Care Policy, and Aging Research; Center for Health Outcomes, Policy & Economics, Rutgers Ernest Mario School of Pharmacy and Rutgers School of Public Health, New Brunswick, NJ, 6Center for Pharmacoepidemiology and Treatment Science, Institute for Health, Health Care Policy, and Aging Research; Department of Biostatistics and Epidemiology, Rutgers School of Public Health; Department of Pediatrics, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ

    Background/Purpose: Juvenile idiopathic arthritis (JIA) is the most common pediatric rheumatic disorder. An increasing array of disease-modifying antirheumatic drugs (DMARDs) have become available to treat…
  • Abstract Number: 0832 • ACR Convergence 2024

    Spatial Transcriptomic Assessment of Histologically Damaged and Unaffected Glomeruli in Class III Pediatric Lupus Nephritis Reveals Distinct Transcriptional Programs

    Sarah McCuaig1, Portia Kreiger1 and Edward Behrens2, 1Children's Hospital of Philadelphia, Philadelphia, PA, 2Children's Hospital of Philadelphia, West Chester, PA

    Background/Purpose: Lupus nephritis (LN) occurs in over 50% of patients with pediatric systemic lupus erythematosus (pSLE) and results in significant morbidity due to suboptimal kidney…
  • Abstract Number: 1265 • ACR Convergence 2024

    Approach to Janus Kinase Inhibition for Juvenile Dermatomyositis Among Childhood Arthritis and Rheumatology Research Alliance (CARRA) and Paediatric Rheumatology European Society (PReS) Providers

    Emily Datyner1, Rebecca Nicolai2, Silvia Rosina3, Angela Hamilton4, Kaveh Ardalan5, Brigitte Bader-Meunier6, Amanda Brown7, Raquel Campanilho-Marques8, Marc Jansen9, Susan Kim10, Bianca Lang11, Liza McCann12, Helga Sanner13, Meredyth Wilkinson14, Belina Yi15, Hanna Kim16, Matthew Sherman17, Stacey Tarvin4 and Charalampia Papadopoulou18, and the CARRA and PReS investigators, 1Monroe Carell Jr. Children's Hospital at Vanderbilt, Nashville, TN, 2Division of Rheumatology, IRCCS Ospedale Pediatrico Bambino Gesù, Rome, Italy, 3IRCCS Istituto Giannina Gaslini, Genoa, Italy, 4Indiana University School of Medicine, Indianapolis, IN, 5Duke University School of Medicine, Durham, NC, 6Necker Hospital, Assistance Publique Hopitaux de Paris, Paris, France, 7University of Arkansas for Medical Sciences, Little Rock, AR, 8Lisbon Academic Medical Centre, Lisboa, Portugal, 9University Medical Center Utrecht, Utrecht, Netherlands, 10University of California, San Francisco, CA, 11Dalhousie University and IWK Health, Halifax, NS, Canada, 12Alder Hey Children's NHS Foundation Trust, Liverpool, England, United Kingdom, 13Oslo University Hospital, Oslo, Norway, 14Great Ormond Street Institute of Child Health, London, United Kingdom, 15Johns Hopkins University School of Medicine, Baltimore, MD, 16National Institute of Arthritis Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, 17DAIT/NIAID/NIH, Washington, DC, 18Great Ormond Street Hospital for Children, NHS Foundation Trust, London, United Kingdom

    Background/Purpose: Janus kinase inhibitors (JAKi) have been proposed as a treatment for idiopathic inflammatory myopathies to target increased interferon signaling. Predominantly retrospective reports have demonstrated…
  • Abstract Number: 1283 • ACR Convergence 2024

    Acute Transverse Myelitis in Pediatric Systemic Lupus Erythematosus

    Meredith Rae1, Emily Beil2, Juan Carlos Torres2, Kristen Fisher2 and Eyal Muscal3, 1Baylor College of Medicine/Texas Children's Hospital, Houston, TX, 2Baylor College of Medicine/Texas Children's Hospital, Houston, 3Baylor College of Medicine, Houston, TX

    Background/Purpose: Transverse myelitis (TM) has an incidence of 1-2% in pediatric SLE and is often a feature of early disease. Most patients ( >60%) have…
  • Abstract Number: 1769 • ACR Convergence 2024

    Top Peripheral Blood Transcriptomic Gene Modules Reveal Functional Annotation and Correlation with Clinical Traits in Juvenile Dermatomyositis (JDM) and Myositis-Specific Autoantibody (MSA) Groups

    Ujana Zajmi1, Megan Darrell1, Amy Kaneshiro1, Adeline Chin1, Adriana Jesus2, Stephen Brooks1, Raphaela Goldbach-Mansky2, Lisa Rider3 and Hanna Kim4, 1NIH/NIAMS, Bethesda, MD, 2NIH/NIAD, Bethesda, MD, 3NIEHS, NIH, Garrett Park, MD, 4National Institute of Arthritis Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD

    Background/Purpose: Myositis-specific autoantibody (MSA) subgroups define phenotypes associated with specific clinical traits and outcomes within JDM, a clinically heterogeneous autoimmune disease. The pathogenesis of JDM…
  • Abstract Number: 1937 • ACR Convergence 2024

    Wellness and Burnout Among Pediatric Rheumatologists in North America- A 2024 CARRA Study

    Kathryn Cook1, Aviya Lanis2, Arielle Hay3, Daniel Glaser4, Sarah Hoffmann5, Lakshmi Moorthy6, Onengiya Harry7, Deepika Singh8 and Sheetal Vora9, and for the CARRA Investigators, 1Akron Children's Hospital, Akron, OH, 2Seattle Children's Hospital, Seattle, WA, 3Nicklaus Children's Hospital, Hollywood, FL, 4Yale University School of Medicine, New Haven, CT, 5Children's Hospital of Richmond at VCU, Richmond, VA, 6Rutgers Robert Wood Johnson Medical School, Metuchen, NJ, 7Brenner Children's Hospital - Wake Forest Baptist Health, Winston-Salem, NC, 8Valley Children's Healthcare, Clovis, CA, 9Atrium Health Levine Children's Hospital, Charlotte, NC

    Background/Purpose: A high proportion of pediatricians experience burnout symptom impacting patient care and academic productivity. Burnout is a state of physical, emotional or mental exhaustion…
  • Abstract Number: 2190 • ACR Convergence 2024

    Uncovering Inborn Errors of Immunity in Pediatric Rheumatology

    Maleewan Kitcharoensakkul1, Natsumon Udomkittivorakul1, Tarin Bigley1, Lance Peterson2, Kevin Baszis3 and Megan Cooper2, 1Washington University in St. Louis, St. Louis, 2Washington University School of Medicine, St. Louis, MO, 3Washington Univ in St. Louis School of Medicine, St Louis, MO

    Background/Purpose: Immune dysregulation, including autoimmunity, is one of the known clinical manifestations of inborn errors of immunity (IEI). We aim to evaluate IEI discovered by…
  • Abstract Number: 2343 • ACR Convergence 2024

    Temporal Trends in and Associations with NSAID Prescription in Adult and Pediatric Patients with IBD

    Adam Mayer1, Rui Xiao2, Andrew Grossman3, Meenakshi Bewtra4, Michael George2 and Pamela Weiss5, 1University of Pennsylvania/Children's Hospital of Philadelphia, Philadelphia, PA, 2University of Pennsylvania, Philadelphia, PA, 3Children's Hospital of Philadelphia, Philadelphia, 4University of Pennsylvania, Philadelphia, 5Children's Hospital of Philadelphia, Philadelphia, PA

    Background/Purpose: The role of nonsteroidal anti-inflammatory drugs (NSAIDs) in the management of musculoskeletal symptoms in patients with inflammatory bowel disease (IBD) and IBD-associated arthritis remains…
  • Abstract Number: 2625 • ACR Convergence 2024

    Brain Injury Markers Correlate with Impaired Executive Function and Disease Activity in Children with Systemic Lupus Erythematosus

    Oscar Mwizerwa1, Justine Ledochowski2, Tala El Tal3, Ganesh Ramanathan2, Sarah Mossad4, Ibrahim Mohamed5, Joanna Law6, Lawrence Ng2, Paris Moaf2, Asha Jeyanathan1, Adrienne Davis7, Ann Yeh2, Linda Hiraki2, Deborah Levy2, Zahi Touma8, Joan Wither9, Busi Zapparoli10, Ashley Danguecan11 and Andrea Knight12, 1The Hospital for Sick Children, Division of Rheumatology, Department of Paediatrics, University of Toronto, The Hospital for Sick Children, Neurosciences and Mental Health, Research Institute, Toronto, ON, Canada, 2The Hospital for Sick Children, Toronto, ON, Canada, 3The Hospital For Sick Children & Children's Hospital of Eastern Ontario (CHEO), Ottawa, ON, The Hospital for Sick Children, Division of Rheumatology, Department of Paediatrics, University of Toronto, Toronto, ON, Canada, 4Hospital for Sick Children, Toronto, ON, Canada, 5The Hospital for Sick Children, Brampton, ON, Canada, 6The Hospital for Sick Children, Division of Rheumatology, Department of Paediatrics, University of Toronto, Toronto, ON, Canada, 7Division of Pediatric Emergency Medicine, Department of Pediatrics, Hospital for Sick Children and University of Toronto, Toronto, ON, Canada, 8University of Toronto, Toronto, ON, Canada, 9University Health Network, Toronto, ON, Canada, 10The Hospital for Sick Children, Etobicoke, ON, Canada, 11The Hospital for Sick Children, Department of Psychology, University of Toronto, Toronto, ON, Canada, 12Division of Rheumatology, The Hospital for Sick Children; Neurosciences and Mental Health, SickKids Research Institute; Department of Paediatrics, University of Toronto, Toronto, ON, Canada

    Background/Purpose: Patients with childhood-onset systemic lupus erythematosus (cSLE) commonly experience impaired executive function (EF), and attribution to neuropsychiatric lupus (NPSLE) is challenging. Serum markers of…
  • Abstract Number: 0370 • ACR Convergence 2024

    Adolescents’ and Providers’ Perceptions of the Transition from Pediatric to Adult Rheumatology

    Julia Witowska, Brett Curtis, Melanie Donahue, Sara Platte, Rebecca Northway and Jacqueline Madison, University of Michigan, Ann Arbor, MI

    Background/Purpose: The transition from pediatric to adult rheumatology is a vulnerable period for adolescents and is associated with greater disease burden. Adolescents require an organized…
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