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Abstracts tagged "Patient reported outcomes"

  • Abstract Number: 1866 • ACR Convergence 2020

    Patient-reported Impact of Axial Spondyloarthritis on Working Life. Results from the Spanish Atlas 2017

    Marco Garrido-Cumbrera1, Eduardo Collantes-Estévez2, Victoria Navarro-Compán3, Pedro Zarco4, Carlos Sastre5, Sergio Sanz-Gomez6, José Correa-Fernández7 and Jordi Gratacós8, 1Health & Territory Research (HTR), Universidad de Sevilla / Spanish Federation of Spondyloarthritis Associations, Sevilla, Spain, 2Rheumatology Department, Reina Sofia University Hospital/ Maimonides Institute for Research in Biomedicine of Cordoba (IMIBIC)/ University of Cordoba, Cordoba, Spain, Córdoba, Spain, 3Hospital Universitario La Paz IdiPaz, Madrid, Pais Vasco, Spain, 4Novartis Farmacéutica Spain, Alcorcon, Madrid, Spain, 5Novartis Pharma AG, Basel, Switzerland, 6Health & Territory Research, Seville, Spain, 7Health & Territory Research (HTR), Universidad de Sevilla, Sevilla, Spain, 8University Hospital Parc Tauli Sabadell, Barcelona, Spain

    Background/Purpose: Axial spondyloarthritis (axSpA) impacts negatively on multiple dimensions of patient’s life, including their working life. The present study aims to evaluate working status, work-related…
  • Abstract Number: 0144 • ACR Convergence 2020

    Age, Income, Education, and Health Conditions Are Associated with Patient Empowerment Among US Adults with Arthritis, but Race and Geography Are Not

    Kathleen Carluzzo1, Erin Knight-Zhang1, Karen Schifferdecker1, Emily Creek2, Rebecca Butcher1 and Guy Eakin2, 1Dartmouth College, Lebanon, NH, 2Arthritis Foundation, Atlanta, GA

    Background/Purpose: The purpose of this study is to understand experiences of empowerment in healthcare visits among US adults with arthritis, and key factors associated with discrepancies…
  • Abstract Number: 0206 • ACR Convergence 2020

    Fifty-Two Week Outcomes of Biologic-Naïve RA Patients Treated with Subcutaneous Abatacept in Japanese Multicenter Investigational Study (ORIGAMI Study)

    Naoto Tamura1, Eiichi Tanaka2, Eisuke Inoue3, Yuri Yoshizawa4, Shigeru Matsumoto5, Hisashi Yamanaka6 and Masayoshi Harigai7, 1Department of Internal Medicine and Rheumatology, Juntendo University School of Medicine, Bunkyō, Tokyo, Japan, 2Department of Rheumatology, Tokyo Women’s Medical University School of Medicine, Tokyo, Japan, 3Department of Rheumatology, Tokyo Women’s Medical University School of Medicine; Showa University Research Administration Center, Showa University, Tokyo, Japan, 4Bristol-Myers Squibb K.K., Tokyo, Japan, 5Ono Pharmaceutical Co., Ltd., Tokyo, Japan, 6Department of Rheumatology, Tokyo Women’s Medical University School of Medicine; Rheumatology, Sanno Medical Center, Tokyo, Japan, 7Department of Rheumatology, Tokyo Women’s Medical University School of Medicine, Shinjuku-ku, Tokyo, Japan

    Background/Purpose: Long-term clinical benefit and patient-reported outcomes (PRO) of subcutaneously-injected abatacept (ABA) in patients with RA in a real-world setting are of therapeutic interest. We…
  • Abstract Number: 0358 • ACR Convergence 2020

    Does Smoking Affect Secukinumab Treatment Outcomes and Safety in Patients with Ankylosing Spondylitis? – Real World Data from German Observational Study

    Elke Riechers1, Uta Kiltz2, Jan Brandt-Jürgens3, Peter Kästner4, Daniel Peterlik5 and Hans-Peter Tony6, 1Hannover Medical School, Hannover, Germany, 2Rheumazentrum Ruhrgebiet, Ruhr-University Bochum, Herne, Germany, 3Rheumatologische Schwerpunktpraxis Berlin, Berlin, Germany, 4Ambulantes Rheumazentrum, Erfurt, Germany, 5Novartis Pharma GmbH, Nürnberg, Germany, 6Rheumatology/Clinical Immunology, Department of Internal Medicine II, Würzburg, Germany

    Background/Purpose: There is growing body of evidence that smoking is associated with more active and severe disease in patients (pts) with ankylosing spondylitis (AS)1,2. The…
  • Abstract Number: 0873 • ACR Convergence 2020

    Impact of Skin Involvement on Disease Burden Among Patients with Psoriatic Arthritis: Data from the Corrona Psoriatic Arthritis/Spondyloarthritis Registry

    Philip Mease1, Robert McLean2, Taylor Blachley2, Laura Anatale-Tardiff3, Christopher Saffore4, Charlie Lovan5 and Alexis Ogdie6, 1Seattle Rheumatology Associates, P.L.L.C., Seattle, WA, 2Corrona, LLC, Waltham, MA, 3Corrona, LLC, Waltham, 4AbbVie Inc., North Chicago, IL, 5AbbVie Inc., North Chicago, 6University of Pennsylvania, Philadelphia, PA

    Background/Purpose: When deciding to start patients with PsA on biologic therapy, rheumatologists may focus on skin involvement in addition to joint symptoms. The purpose of…
  • Abstract Number: 1201 • ACR Convergence 2020

    Effect of Filgotinib on Pain in Patients with Rheumatoid Arthritis: Results from Phase 3 Clinical Trials

    Peter Taylor1, Arthur Kavanaugh2, Peter Nash3, Janet Pope4, Beatrix Bartok5, Ken Hasegawa5, Shangbang Rao5, Sander Strengholt6 and Rene Westhovens7, 1Botnar Research Centre, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom, 2Division of Rheumatology, Allergy, & Immunology, University of California San Diego Medical School, San Diego, CA, 3School of Medicine Griffith University, Brisbane, Queensland, Australia, 4Department of Medicine, University of Western Ontario, St. Joseph's Health Centre, London, ON, Canada, 5Gilead Sciences, Inc., Foster City, CA, 6Galapagos BV, Leiden, Netherlands, 7University Hospitals Leuven, Belgium, Leuven, Belgium

    Background/Purpose: RA patients (pts) often suffer substantial pain despite ongoing treatment (tx) and regard pain control as a top tx goal. Filgotinib (FIL)—a potent, oral…
  • Abstract Number: 1319 • ACR Convergence 2020

    Disease Activity and Mental Health of as Patients: A Cross-section Study with Self-assessments Based on Smart System of Disease Management (SSDM) Mobile Tools

    Hui Song1, Hua Wei2, Miaojia Zhang3, Lijun Wu4, Zhenbiao Wu5, Aichun Chu6, Bei Wang7, Wenqiang Fan8, Xiaohan Wang9, Xiaoqi Chen10, Henglian Wu11, Wenyu Zhou12, Fei Xiao13, Hui Xiao14, Yuhua Jia13, Bing Wu13 and Jing Lu15, 1Beijing Jishuitan Hospital, Beijing, China (People's Republic), 2Northern Jiangsu People's Hospital, Yangzhou, China (People's Republic), 3Jiangsu Province Hospital, The first affiliated hospital of Nanjing medical university, Nanjing, China (People's Republic), 4People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang, China (People's Republic), 5The First Affiliated Hospital of The Air Force Medical University, Xi'an, Shanxi, China (People's Republic), 6Remin Hospital of Wuhan University Hubei General Hospital, Wuhan, China (People's Republic), 7Beijing Hospital of Traditional Chinese Medicine, Beijing, China (People's Republic), 8Central Hospital of XinXiang, Xinxiang, China (People's Republic), 9Anyang district hospital, Anyang, Henan, China (People's Republic), 10Zhongnan Hospital of Wuhan University, Wuhan, China (People's Republic), 11Dongguan Donghua Hospital, Dongguan, Guangdong, China (People's Republic), 12Wuhan No. 4 Hospital, Wuhan, China (People's Republic), 13Shanghai Gothic Internet Technology Co., Ltd., Shanghai, China (People's Republic), 14Shanghai Gothic Internet Technology Co., Ltd., Shanghai, Shanghai, China (People's Republic), 15First Affiliated Hospital of China Medical University, Shenyang, China (People's Republic)

    Background/Purpose: WHO survey showed that the prevalence of anxiety and depression in Chinese population and Chinese patients with chronic diseases were between 3.1% - 4.2%…
  • Abstract Number: 1600 • ACR Convergence 2020

    Relationship Between Electronic Health Record Vendor and Performance on Patient-reported Outcome Quality Measures in the ACR’s Rheumatology Informatics System for Effectiveness (RISE) Registry

    Nevin Hammam1, Gabriela Schmajuk2, Jing Li3, Michael Evans1, Julia Kay1 and Jinoos Yazdany3, 1UCSF, San Francisco, CA, 2University of California, San Francisco, Atherton, CA, 3University of California, San Francisco, San Francisco, CA

    Background/Purpose: Routine collection of disease activity and patient reported outcomes (PROs) such as functional status assessment in rheumatoid arthritis (RA) are nationally endorsed quality measures…
  • Abstract Number: 1880 • ACR Convergence 2020

    Association of Healthcare Utilization and Costs with Patient-Reported Outcomes in Patients with Ankylosing Spondylitis

    Alexis Ogdie1, Mark Hwang2, Phani Veeranki3, Alexandria Portelli3, Steven Sison3, Jason Shafrin3, Sofia Pedro4, Esther Yi5 and Kaleb Michaud6, 1Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, 2McGovern Medical School at the University of Texas Health Science Center at Houston, Houston, TX, 3PRECISIONheor, Los Angeles, 4FORWARD-The National Data Bank for Rheumatic Diseases, Wichita, 5Novartis Pharmaceuticals Corporation, East Hanover, NJ, 6FORWARD-The National Data Bank for Rheumatic Diseases; University of Nebraska Medical Center, Wichita

    Background/Purpose: Treatments for ankylosing spondylitis (AS) have been shown to improve patient-reported outcome (PRO) measures in clinical studies; however, healthcare decision makers have limited ability…
  • Abstract Number: 0147 • ACR Convergence 2020

    The Interpretation of Patient-reported Outcomes in Rheumatoid Arthritis: Do Clinical Trials Adequately Evaluate Meaningful Improvements for Patients?

    Peter Taylor1, Robin Dore2, Kate Williams3, Sarah Acaster3, Jenya Antonova4 and Mark Genovese5, 1Botnar Research Centre, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom, 2Private practice, Tustin, CA, 3Acaster Lloyd Consulting, London, United Kingdom, 4Gilead Sciences, Foster City, CA, 5Gilead Sciences, Inc., Foster City, CA

    Background/Purpose: The importance of patient-relevant outcomes, such as pain, fatigue and physical functioning, has been long established in the field of rheumatoid arthritis (RA). Patient-reported…
  • Abstract Number: 0236 • ACR Convergence 2020

    Safety and Usability of Infliximab Administration by Auto-injector (AI) and Pre-filled Syringe (PFS) in Patients with Active Rheumatoid Arthritis (RA): Patient-reported Experience from a Multicenter, Randomized Controlled Pivotal Trial

    Rene Westhovens1, DaeHyun Yoo2, Piotr Wiland3, Marek Zawadzki4, Delina Ivanova5, Alfredo Berrocal Kasay6, Elias Chalouhi7, Eva Balázs8, SangJoon Lee9, SungHyun Kim9, JeeHye Suh9, NooRi Han9 and HoJae Lee9, 1University Hospitals Leuven, Belgium, Leuven, Belgium, 2Hanyang University Hospital for Rheumatic Diseases, Seoul, Republic of Korea, 3Medical Univeristy, Wroclaw, Poland, 4Medical Univeristy, Dpt of Rheumatology , Wroclaw, Wroclaw, Poland, 5Diagnostic-Consultative Center Aleksandrovska EOOD, Sofia, Bulgaria, 6ABK Reuma SRL, LIMA, Peru, 7Clinica Internacional Sede Lima, Lima, Peru, 8Dr. Bugyi István Hospital, Szentes, Hungary, 9Celltrion, Inc., Incheon, Republic of Korea

    Background/Purpose: The subcutaneous (SC) formulation of CT-P13 received marketing authorization for RA from the EMA by demonstrating non-inferiority compared to CT-P13 intravenous for efficacy in…
  • Abstract Number: 0360 • ACR Convergence 2020

    Does Smoking Affect Secukinumab Treatment Outcomes and Safety in Patients with Psoriatic Arthritis? – Real World Data from German Observational Study

    Elke Riechers1, Uta Kiltz2, Jan Brandt-Jürgens3, Peter Kästner4, Daniel Peterlik5 and Hans-Peter Tony6, 1Hannover Medical School, Hannover, Germany, 2Rheumazentrum Ruhrgebiet, Ruhr-University Bochum, Herne, Germany, 3Rheumatologische Schwerpunktpraxis Berlin, Berlin, Germany, 4Ambulantes Rheumazentrum, Erfurt, Germany, 5Novartis Pharma GmbH, Nürnberg, Germany, 6Rheumatology/Clinical Immunology, Department of Internal Medicine II, Würzburg, Germany

    Background/Purpose: Several studies have shown an negative association between smoking status and psoriatic arthritis (PsA) clinical outcomes1,2. The German non-interventional study AQUILA provides real-world data…
  • Abstract Number: 0884 • ACR Convergence 2020

    Comparison of Disease Control Thresholds in Psoriatic Arthritis: Results from the Corrona Psoriatic Arthritis/Spondyloarthritis Registry

    Philip Mease1, Robert McLean2, Taylor Blachley2, Laura Anatale-Tardiff3, Christopher Saffore4, Patrick Zueger4 and Alexis Ogdie5, 1Seattle Rheumatology Associates, P.L.L.C., Seattle, WA, 2Corrona, LLC, Waltham, MA, 3Corrona, LLC, Waltham, 4AbbVie Inc., North Chicago, IL, 5University of Pennsylvania, Philadelphia, PA

    Background/Purpose: There is no single accepted measure of low/minimal disease activity (LDA/MDA) for patients with PsA; thus, describing the characteristics of real-world patients meeting different…
  • Abstract Number: 1214 • ACR Convergence 2020

    Association Between Changes in C-reactive Protein at Week 12 and Patient-Reported Outcomes at Week 24 with Sarilumab Therapy Across Three Pivotal Phase 3 Studies

    John Tesser1, Grace Wright2, Vibeke Strand3, Jeffrey Kaine4, Karina Maslova5, Gregory St John6, Kerri Ford5, Amy Praestgaard5 and Ernest Choy7, 1Arizona Arthritis & Rheumatology Associates, Phoenix, AZ, 2Association of Women in Rheumatology, New York, NY, 3Division of Immunology/Rheumatology, Stanford University, Palo Alto, CA, 4Independent Rheumatology Consultant, Sapphire, NC, 5Sanofi, Cambridge, MA, 6Regeneron Pharmaceuticals Inc, Tarrytown, NY, 7CREATE Centre, Cardiff University, Cardiff, Wales, United Kingdom

    Background/Purpose: Evaluation of response to RA therapy at 12 weeks after initiation is recommended in treatment guidelines. CRP response after 12 weeks of therapy may…
  • Abstract Number: 1322 • ACR Convergence 2020

    Prevalence and Associated Factors of Sleep Disorders in Patients with Axial Spondyloarthritis. Results from the European Map of Axial Spondyloarthritis (EMAS)

    Marco Garrido-Cumbrera1, Victoria Navarro-Compán2, Laura Christen3, Christine Bundy4, Raj Mahapatra5, Souzi Makri6, Carlos-Jesus Delgado-Domínguez7, José Correa-Fernández8 and Denis Poddubnyy9, 1Health & Territory Research (HTR), Universidad de Sevilla / Spanish Federation of Spondyloarthritis Associations, Sevilla, Spain, 2Hospital Universitario La Paz IdiPaz, Madrid, Pais Vasco, Spain, 3Novartis Pharma AG, Basel, Switzerland, 4Cardiff University, Cardiff, United Kingdom, 5Axial Spondyloarthritis International Federation, London, United Kingdom, 6Cyprus League Against Rheumatism, Nicosia, Cyprus, 7Health & Territory Research, Seville, Spain, 8Health & Territory Research (HTR), Universidad de Sevilla, Sevilla, Spain, 9Charité – Universitätsmedizin Berlin, Berlin, Germany

    Background/Purpose: Sleep is an essential health aspect that is often impacted in patients with axial spondyloarthritis (axSpA). This analysis aims to assess the prevalence and…
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