Abstracts tagged "patient outcomes"

Abstract Number: 2910 • 2018 ACR/ARHP Annual Meeting
Development of a Rheumatoid Arthritis Global Outcome Measure to Enable Comparisons of Patient Experiences across Treatment Arms in Randomized Clinical Trials
Liana Fraenkel¹, W. Benjamin Nowell², Carole Wiedmeyer², Zhenglin Wei³, Kaleb Michaud⁴, Tuhina Neogi⁵, Christine Ramsey¹ and David Broniatowski³, ¹Yale University School of Medicine, New Haven, CT, ²Global Healthy Living Foundation, Upper Nyack, NY, ³George Washington University, Washington, DC, ⁴Rheumatology, University of Nebraska Medical Center, Omaha, NE, ⁵Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MA
Background/Purpose: Randomized controlled trials currently report benefits and adverse events (AEs) separately, and therefore do not permit comparisons of patients’ overall experiences on one treatment…
Abstract Number: 594 • 2018 ACR/ARHP Annual Meeting
Identification of Tocilizumab Treated RA Patients, Whom Are Not Likely to Show Long-Term Clinical Benefit; Reanalysis of the Biomarker Sub-Study of LITHE
Anne C. Bay-Jensen¹, Christian S. Thudium¹, Claus Christiansen² and Morten A. Karsdal¹, ¹Nordic Bioscience, Herlev, Denmark, ²Nordic Bioscience, Clinical Development, Herlev, Denmark
Background/Purpose: Tocilizumab, anti-interleukin 6 receptor (IL-6R) therapy, is an effective treatment of rheumatoid arthritis (RA). However, a significant amount of patients do not respond adequately…
Abstract Number: 1387 • 2018 ACR/ARHP Annual Meeting
Fatigue in Patients with Rheumatoid Arthritis As Compared to Different Groups of Cancer Patients
Jens Gert Kuipers¹, Michael Koller², Ulrich Rueffer³, Florian Zeman², Karolina Mueller⁴ and Joachim Weis⁵, ¹Clinic for Internal Rheumatology, Red Cross Hospital Bremen, Bremen, Germany, ²Center of Clinical Studies, University Hospital Regensburg, Regensburg, Germany, ³German Fatigue Society, Cologne, Germany, ⁴Center for Clinical Studies, University Hospital Regensburg, Regensburg, Germany, ⁵University Clinic Centre Freiburg, Freiburg, Germany
Background/Purpose: Fatigue is a common symptom in patients with rheumatoid arthritis (RA) as well as patients with cancer. Fatigue considerably reduces the quality of life…
Abstract Number: 1391 • 2018 ACR/ARHP Annual Meeting
Patient-Acceptable Symptom State in Psoriatic Arthritis: Prevalence and Associated Factors in Real Clinical Practice
Rubén Queiro¹, Juan Cañete², Carlos Alberto Montilla-Morales³ and Miguel A. Abad⁴, ¹Rheumatology Division, HUCA, Oviedo, Spain, ²Rheumatology Service, Hospital Clínic de Barcelona, Barcelona, Spain, ³Hospital Clínico Universitario de Salamanca. Spain, Salamanca, Spain, ⁴FEA Reumatología, Hospital Virgen del Puerto, Cáceres, Spain
Background/Purpose: Treatment goals in psoriatic arthritis (PsA) are remission or low disease activity. We know little about whether these objectives correlate well with a patient-acceptable…
Abstract Number: 1392 • 2018 ACR/ARHP Annual Meeting
Decreased Injection Site Pain Associated with New Etanercept Formulation in Patients with Rheumatoid Arthritis or Psoriatic Arthritis
Stanley Cohen¹, Ahmed Samad², Elaine Karis², Bradley S. Stolshek², Mona Trivedi², Hao Zhang², Girish A. Aras², Greg Kricorian² and James Chung², ¹Metroplex Clinical Research Center, Dallas, TX, ²Amgen Inc., Thousand Oaks, CA
Background/Purpose: Injection site pain (ISP) is a component of the patient experience with injectable drugs. A new formulation of etanercept was developed to reduce ISP.…
Abstract Number: 1407 • 2018 ACR/ARHP Annual Meeting
Differences in the Measurement Properties of the Patient-Reported Outcomes Measurement Information System Physical Function Short-Form 10a Among Racial/Ethnic Minorities with Rheumatoid Arthritis
Zara Izadi¹, Patricia Katz², Gabriela Schmajuk³, Julie Gandrup⁴, Jing Li⁵, Milena Gianfrancesco⁶ and Jinoos Yazdany⁷, ¹Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, ²University of California San Francisco, San Francisco, CA, ³Medicine/Rheumatology, University of California - San Francisco, San Francisco, CA, ⁴Rheumatology, Odense University Hospital, Odense, Denmark, ⁵Medicine, UC San Francisco, San Francisco, CA, ⁶Medicine/Rheumatology, University of California, San Francisco, San Francisco, CA, ⁷University of California, San Francisco, San Francisco, CA
Background/Purpose: Most studies evaluating patient-reported outcomes such as the PROMIS Physical Function Short Form 10a (PF10a) in rheumatoid arthritis (RA) have been performed in white…
Abstract Number: 1602 • 2018 ACR/ARHP Annual Meeting
Disease Characteristics, Quality of Life, and Work Productivity By Enthesitis Sites: Real-World Data from the US Corrona Psoriatic Arthritis/Spondyloarthritis (PsA/SpA) Registry
Philip J. Mease¹, Mei Liu², Sabrina Rebello³, Winnie Hua², Robert R. McLean², Peter Hur⁴ and Alexis Ogdie⁵, ¹Swedish Medical Center and University of Washington, Seattle, WA, ²Corrona, LLC, Waltham, MA, ³Corrona, LLC, Southborough, MA, ⁴Novartis Pharmaceuticals Corporation, East Hanover, New Jersey, USA, East Hanover, NJ, ⁵Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA
Background/Purpose: Prior studies showed psoriatic arthritis (PsA) patients with enthesitis had greater disease burden than patients without enthesitis, yet it is unknown whether the impact…
Abstract Number: 1643 • 2018 ACR/ARHP Annual Meeting
Psa Impact of Disease Questionnaire Scores Are Correlated with Disease Activity, As Measured By Cdapsa in Patients with Psa
Ana-Maria Orbai¹, Klaus Krüger², Frank Behrens³, Uta Kiltz⁴, Benoit Guerette⁵, Lillian Mellars⁵, Michele Brunori⁵ and Jürgen Wollenhaupt⁶, ¹Johns Hopkins University School of Medicine, Baltimore, MD, ²Medical Centre of Rheumatology, Munich, Germany, ³Clinical Research Rheumatology and Fraunhofer Institute IMETranslation, Goethe University, Frankfurt, Germany, ⁴Rheumazentrum Ruhrgebiet, Herne, Germany, ⁵Celgene Corporation, Summit, NJ, ⁶Schön-Klinik Hamburg-Eilbek Teaching Hospital of the University of Hamburg, Hamburg, Germany
Background/Purpose: We examined clinical correlations between disease activity, as measured with the Clinical Disease Activity for PsA (cDAPSA) components and PsA life impact/health-related quality of…
Abstract Number: 1689 • 2018 ACR/ARHP Annual Meeting
Explaining the Discrepancy between Physician and Patient-Reported Measures of Disease Activity in Systemic Lupus Erythematosus
Nathaniel J. Harris¹, Amanda M. Eudy² and Megan E. B. Clowse², ¹Department of Medicine, Duke University, Durham, NC, ²Department of Medicine, Division of Rheumatology and Immunology, Duke University, Durham, NC
Explaining the Discrepancy between Physician and Patient-Reported Measures of Disease Activity in Systemic Lupus Erythematosus Background/Purpose: Patient-reported measures of disease activity provide useful adjuncts to…
Abstract Number: 2293 • 2018 ACR/ARHP Annual Meeting
Subcutaneous Intravenous Immunoglobulins in Idiopathic Inflammatory Myopathies: Analysis of a Monocentric Cohort
Emanuele Calabresi¹, Simone Barsotti², Elisa Cioffi³, Alessandra Tripoli¹, Andrea Delle Sedie¹, Laura Bazzichi⁴, Ornella Mazzarella¹, Rossella Neri⁴ and Marta Mosca¹, ¹Rheumatology Unit, University of Pisa, Pisa, Italy, ²Department of Medical Biotechnologies, University of Siena, Siena, Italy, ³Rheumatology Unit, Rheumatology Unit, University of Pisa, Pisa, Italy, ⁴Rheumatology Unit, University of Pisa, PISA, Italy
Background/Purpose: Despite the absence of specific guidelines, the treatment with intravenous immunoglobulins (IvIg) is considered effective in patients with refractory idiopathic inflammatory myopathies (IIM). Recently,…
Abstract Number: 2359 • 2018 ACR/ARHP Annual Meeting
Systemic Lupus Erythematous Outcome Concerns: Identifying Pain As the Major Discrepancy between Rheumatologists and Patients
Isabela Bertoglio¹, Glaucia Abrahão¹, Eloisa Bonfa² and Michelle Lopes³, ¹Rheumatology, Hospital das Clínicas da Faculdade de Medicina da USP, São Paulo, Brazil, ²Rheumatology Division, Hospital das Clinicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, ³Rheumatology Division, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil
Background/Purpose: Now-a-days there is a growing trend of switching to a more patient-centered healthcare system, with a widespread use of patient-reported outcomes (PROs). However, most…
Abstract Number: 337 • 2017 ACR/ARHP Annual Meeting
Patient-Reported Flares Were Correctly Predicted By an Algorithm Using Machine-Learning Statistics on Activity Tracker Data on Steps, in a Longitudinal 3-Month Study of 170 Patients with Rheumatoid Arthritis (RA) or Axial Spondyloarthritis (axSpA)
Laure Gossec¹, Frédéric Guyard², Didier Leroy³, Thomas Lafargue², Michel Seiler³, Charlotte Jacquemin¹, Anna Molto⁴, Jeremie Sellam⁵, Violaine Foltz¹, Frédérique Gandjbakhch¹, Christophe Hudry⁶, Stéphane Mitrovic¹, Bruno Fautrel¹ and Herve Servy⁷, ¹UPMC University Paris 06, Pitié-Salpétrière Hospital, Paris, France, ²IMT, Orange, Nice, France, ³Healthcare, Orange, Paris, France, ⁴Hôpital Cochin, Department of Rheumatology, Paris Descartes University, Paris, France, ⁵Rheumatology, Saint-Antoine Hospital, Paris, France, ⁶AP-HP Hôpital Cochin, Paris, France, ⁷e-health services, Sanoia, Gemenos, France
Background/Purpose: The natural history of RA and axSpA comprises periods of low disease activity and flares. However, there are few data linking patient-reported flares to…
Abstract Number: 2535 • 2017 ACR/ARHP Annual Meeting
Patient Outcomes from a Tertiary Center Combined Rheumatology-Dermatology Clinic
Charis Gn¹, Delaney Conway², Joanne Cunha³, Abrar Qureshi⁴, So Yeon Paek⁵ and Anthony M. Reginato⁶, ¹Division of Rheumatology, The Warren Alpert Medical School of Brown University, Providence, RI, ²Internal Medicine, Rhode Island Hospital, The Warren Alpert Medical School of Brown University, Providence, RI, ³Division of Rheumatology, The Warren Alpert Medical School of Brown University, East Providence, RI, ⁴Dermatology, Rhode Island Hospital, The Warren Alpert Medical School of Brown University, Providence, RI, ⁵Departmet of Dermatology, The Warren Alpert Medical School of Brown University, Providence, RI, ⁶Rhode Island Hospital, The Warren Alpert School of Medicine at Brown University, Providence, RI
Background/Purpose: Many autoimmune diseases have both musculoskeletal and cutaneous manifestations, which historically have been managed separately by rheumatologists and dermatologists. Given the complex presentation of…
Abstract Number: 358 • 2017 ACR/ARHP Annual Meeting
Patients and Physicians Have Different Perceptions of the Relative Bother of the Symptoms and Impacts on Daily Activities in Psoriasis and Psoriatic Arthritis
M. Elaine Husni^1,2, Anthony Fernandez¹, Rakesh Singh³, Brett Hauber⁴, Jessie Sutphin⁴, Joshua Posner⁴ and Arijit Ganguli³, ¹Cleveland Clinic, Cleveland, OH, ²Rheumatology Dept A50, Cleveland Clinic Foundation, Cleveland, OH, ³AbbVie Inc., North Chicago, IL, ⁴RTI Health Solutions, Research Triangle Park, NC
Background/Purpose: Psoriasis and psoriatic arthritis arise from the same immune system response but result in different symptoms and impacts on daily activities. A patient with…
Abstract Number: 2693 • 2017 ACR/ARHP Annual Meeting
Relationships between Levels of Patient Activation, Self-Efficacy, and Demographic Variables in Systemic Sclerosis
Janet L. Poole¹, Veronica J. Berrocal², Jennifer Serrano³, Erica Bush³ and Dinesh Khanna³, ¹Health Sciences Ctr OT Program, 1 University of New Mexico, Albuquerque, NM, ²Div of Rheumatology, University of Michigan, Ann Arbor, MI, ³University of Michigan, Ann Arbor, MI
Background/Purpose: Patient activation refers to the ability and confidence people have to be engaged in managing their health care [Hibbard, 2004]. Knowledge and beliefs about…

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