ACR Meeting Abstracts

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Abstracts tagged "pain"

  • Abstract Number: 1821 • 2019 ACR/ARP Annual Meeting

    Tildrakizumab Efficacy for Psoriatic Arthritis: 24-week Analysis of Swollen and Tender Joint Counts and Pain

    Ana-Maria Orbai 1, Rocco Ballerini 2, Richard C. Chou 3, Stephen Rozzo 2, Alan Mendelsohn2 and Luis R. Espinoza 4, 1Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, 2Sun Pharmaceutical Industries, Inc., Princeton, NJ, USA, Princeton, NJ, 3University at Buffalo School of Medicine and Biomedical Sciences, Buffalo, NY, USA, Buffalo, NY, 4Section of Rheumatology, LSU Health Sciences Center, New Orleans, LA, New Orleans, LA

    Background/Purpose: Tildrakizumab (TIL), a high-affinity anti–interleukin-23p19 monoclonal antibody, is approved to treat moderate-to-severe plaque psoriasis. A randomized, double-blind, multidose, placebo (PBO)-controlled, phase 2b study (NCT02980692)…
  • Abstract Number: 1878 • 2019 ACR/ARP Annual Meeting

    Quantifying the Placebo Effect After Intra-Articular Injections: Implications for Trials and Practice

    Sebastian Rodriguez-Garcia1, Raul Castellanos-Moreira 2, Jacqueline Uson-Jaeger 3, ESPERANZA NAREDO 4 and Loreto Carmona 5, 1Rheumatology Department. Hospital Clínic Barcelona, Barcelona, Spain, 2Rheumatology Department. Hospital Clínic Barcelona, Barcelona, Catalonia, Spain, 3Hospital Universitario de Mostoles, Madrid, Spain, 4Rheumatology Department, Joint and Bone Research Unit. Hospital Universitario Fundación Jiménez Díaz, Universidad Autónoma, MADRID, Spain, 5Instituto de Salud Musculoesquelética - Inmusc., Madrid, Spain

    Background/Purpose: In recent years, diverse compounds for intra-articular (IA) administration were brought into the market with a subsequent significant and heterogeneous literature production. Understanding the efficacy…
  • Abstract Number: 1879 • 2019 ACR/ARP Annual Meeting

    The Relation of Pain Sensitization and Conditioned Pain Modulation to Pain Patterns in Knee Osteoarthritis: The Multicenter Osteoarthritis Study

    Lisa Carlesso1, Laura Frey Law 2, Na Wang 3, Michael Nevitt 4, Beth Lewis 5 and Tuhina Neogi 3, 1McMaster University, Hamilton, ON, Canada, 2University of Iowa, Iowa City, IA, 3Boston University School of Medicine, Boston, MA, 4University of California at San Francisco, San Francisco, CA, 5University of Alabama at Birmingham, Birmingham, AL

    Background/Purpose: Intermittent pain progresses to constant pain in some, but not all, individuals with knee osteoarthritis (OA). Differing pain mechanisms may underlie these transitions. Later…
  • Abstract Number: 1881 • 2019 ACR/ARP Annual Meeting

    Association of Pain Centralization with DMARD Response in Active RA

    Andrew Heisler1, Jing Song 2, Dorothy Dunlop 1, Alyssa Wohlfahrt 3, Marcy Bolster 4, Wendy Marder 5, Clifton Bingham 6, Daniel Clauw 7, Tuhina Neogi 8 and Yvonne Lee 9, 1Northwestern University Feinberg School of Medicine, Chicago, IL, 2Northwestern University Feinberg School of Medicine, Worthington, OH, 3Brigham and Woman's Hospital, Boston, MA, 4Massachusetts General Hospital, Boston, MA, 5Division of Rheumatology, Department of Internal Medicine, Michigan Medicine, Ann Arbor, 6Johns Hopkins University, Baltimore, MD, 7Division of Rheumatology, Department of Internal Medicine and Division of Anesthesia, Michigan Medicine, Ann Arbor, MI, 8Boston University School of Medicine, Boston, MA, 9Northwestern University Feinberg School of Medicine, Chicago

    Background/Purpose: Despite the availability of potent disease modifying anti-rheumatic drugs (DMARDs), a significant percentage of rheumatoid arthritis (RA) patients do not achieve low disease activity…
  • Abstract Number: 1883 • 2019 ACR/ARP Annual Meeting

    Elucidating Pain Mechanisms in Polyarticular Juvenile Idiopathic Arthritis Patients

    Jaymin Upadhyay1, Diana Sibai 1, Robert Labadie 2, Jordan Lemme 3, Christine Sieberg 2, Kirsten Ecklund 4, David Borsook 4 and Robert Sundel 4, 1Boston Children's Hospital, Harvard Medical School, Boston, MA, 2Boston Children’s Hospital, Harvard Medical School, Boston, MA, 3Boston Children's Hospital, Harvard Medical School, Boston, 4Boston Children’s Hospital, Harvard Medical School, Boston

    Background/Purpose: Despite a broad range of available therapeutics, pain remains poorly treated in many juvenile idiopathic arthritis (JIA) patients1-2. For some patients, the level of pain…
  • Abstract Number: 2089 • 2019 ACR/ARP Annual Meeting

    Restricting Activity to Evade Knee Symptoms Is Associated with Worse Physical Function and Radiographic Osteoarthritis

    Louise Thoma1, Jason Jakiela 2, Hiral Master 1, Dana Voinier 2, Meredith Christiansen 2 and Daniel White 1, 1University of Delaware, Newark, DE, 2University of Delaware, Newark

    Background/Purpose: Activity restriction (i.e. limiting or avoiding normal activity) is a common strategy to reduce, and sometimes eliminate, knee symptoms. Knee symptoms, such as pain,…
  • Abstract Number: 2171 • 2019 ACR/ARP Annual Meeting

    Functional Exercise for Adults with Chronic Nonspecific Low Back Pain

    Emilia Moreira1, Anamaria Jones 1, Eider Lima 1, Fabio Jennings 2 and Jamil Natour 2, 1Federal University of Sao Paulo, Sao Paulo, Sao Paulo, Brazil, 2Federal University of São Paulo, São Paulo, Brazil

    Background/Purpose: To assess the effectiveness of a functional exercise program for pain, functional capacity, general health, kinesiophobia, medication consumption and patient satisfaction in adults with chronic…
  • Abstract Number: 2183 • 2019 ACR/ARP Annual Meeting

    Relation of Intra-Articular Knee Mineralization on CT to Knee Pain in People with or at Risk of Knee Osteoarthritis

    Tuhina Neogi1, John Lynch 2, Mohamed Jarraya 3, David Felson 4, Na Wang 1, Michael Nevitt 2, James Torner 5, Beth Lewis 6 and Ali Guermazi 1, 1Boston University School of Medicine, Boston, MA, 2University of California at San Francisco, San Francisco, CA, 3Mercy Catholic Medical Center, Darby, 4Boston University School of Medicine, Department of Rheumatology, Boston, 5University of Iowa at Iowa City, Iowa City, 6University of Alabama at Birmingham, Birmingham, AL

    Background/Purpose: Intra-articular (i.a.) calcium crystal deposition is common in knee osteoarthritis (OA), particularly in end-stage disease. It is possible that low-grade inflammation related to crystals…
  • Abstract Number: 2594 • 2018 ACR/ARHP Annual Meeting

    Median Time to Pain Improvement in Patients with Psoriatic Arthritis Treated with Tofacitinib

    Kurt de Vlam1, Alexis Ogdie2, Andrew G Bushmakin3, Joseph C Cappelleri3, Roy Fleischmann4, Peter C. Taylor5, Valderilio F Azevedo6, Lara Fallon7, Anna Maniccia8, John Woolcott9 and Philip J. Mease10, 1UZ Leuven, Leuven, Belgium, 2University of Pennsylvania, Philadelphia, PA, 3Pfizer Inc, Groton, CT, 4University of Texas Southwestern Medical Center, Dallas, TX, 5University of Oxford, Oxford, United Kingdom, 6Universidade Federal do Paraná, Curitiba, Brazil, 7Pfizer Canada, Montreal, QC, Canada, 8Pfizer Inc, New York, NY, 9Pfizer Inc, Collegeville, PA, 10Swedish Medical Center and University of Washington, Seattle, WA

    Background/Purpose: Pain is a core domain of psoriatic arthritis (PsA).1 Rapid, sustained pain reduction is a priority for patients (pts) and physicians when choosing treatment.…
  • Abstract Number: 2652 • 2018 ACR/ARHP Annual Meeting

    Engaging the Cholinergic Anti-Inflammatory Pathway By Stimulating the Vagus Nerve Reduces Pain and Fatigue in Patients with SLE

    Cynthia Aranow1, Martin Lesser2, Meggan Mackay1, Erik Anderson3, Theodoros P. Zanos2, Timir Datta-Chaudhuri2, Chad Bouton2, Kevin J. Tracey4 and Betty Diamond1, 1The Feinstein Institute for Medical Research, Manhasset, NY, 2Feinstein Institute for Medical Research, Manhasset, NY, 3Autoimmune and Musculoskeletal Disease, The Feinstein Institute for Medical Research, Manhasset, NY, 4Laboratory of Biomedical Science, Feinstein Institute for Medical Research, Manhasset, NY

    Background/Purpose:   Musculoskeletal (MS) pain is a common symptom of patients with Systemic Lupus Erythematosus (SLE) affecting up to 95% of patients and contributing to…
  • Abstract Number: 2868 • 2018 ACR/ARHP Annual Meeting

    Tender Joint Count May Not Reflect Inflammatory Activity in Established Rheumatoid Arthritis Patients; Results from a Longitudinal Study of Tocilizumab

    Hilde B Hammer1, Inger Marie Jensen Hansen2, Pentti Järvinen3, Marjatta Leirisalo-Repo4, Michael Ziegelasch5, Birte Agular6 and Lene Terslev7, 1Dept. of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, 2Rheumatology, Svendborg Hospital, Svendborg, Denmark, 3Rheumatology, Kiljava Medical Research, Kiljavan, Finland, 4Rheumatology, University of Helsinki, Helsinki, Finland, 5Rheumatology, University Hospital, Linköping, Linköping, Sweden, 6Roche, Copenhagen, Denmark, 7Rheumatology, Rigshospitalet Glostrup, Copenhagen, Denmark

    Background/Purpose: Tender joints may be caused by non-inflammatory pathologies but are still included in composite scores like CDAI. The present objective was to explore the…
  • Abstract Number: 405 • 2018 ACR/ARHP Annual Meeting

    Feasibility of Enabling Self-Management and Coping with Arthritic Pain Using Exercise (ESCAPE-Pain) Programme for Knee Osteoarthritis in Malaysia

    Muhammad Kamil Che Hasan1,2, Emma Stanmore2 and Chris Todd2, 1Kulliyyah (Faculty) of Nursing, International Islamic University Malaysia (IIUM), Kuantan Pahang, Malaysia, 2Division of Nursing, Midwifery and Social Work, The University of Manchester, Manchester, United Kingdom

    Background/Purpose: In Malaysia around one in ten older people are diagnosed with osteoarthritis (OA), with the knee being one of the most commonly affected areas.…
  • Abstract Number: 447 • 2018 ACR/ARHP Annual Meeting

    Discriminating between Central & Peripheral Pain Sensitization Using a Slowly Repeated Evoked Pain Protocol

    Manuel Romero1, Stephen Bruehl2, Gustavo A Reyes del Paso3 and Pablo De la Coba3, 1University Hospital of Jaén, Jaén, Spain, 2Department of Anesthesiology, Vanderbilt University, Nashville, TN, 3Department of Psychology, University of Jaén, Jaén, Spain

    Background/Purpose: In a prior study, the response of pain sensitization by fibromyalgia (FM) patients to a protocol of Slowly Repeated Evoked Pain (SREP)* was strongly…
  • Abstract Number: 450 • 2018 ACR/ARHP Annual Meeting

    Injection Site Reaction Associated with Subcutaneous Biologic Agents and Methotrexate. Analysis from the Rhumadata® Clinical Database and Registry

    Denis Choquette1, Louis Bessette2, Jacques Brown2, Boulos Haraoui1, Frédéric Massicotte1, Jean-Pierre Pelletier1, Jean-Pierre Raynauld1, Marie-Anaïs Rémillard1, Diane Sauvageau1, Angèle Turcotte2, Édith Villeneuve1 and Louis Coupal1, 1Rheumatology, Institut de Recherche en Rhumatologie de Montréal (IRRM), Montréal, QC, Canada, 2Rheumatology, Centre de l'Ostéoporose et de Rhumatologie de Québec (CORQ), Québec, QC, Canada

    Background/Purpose: Injection Site Reaction (ISRs) are associated with the subcutaneous (SC) route of administration of all biologic agents, and 3% to 15% of patients reports…
  • Abstract Number: 933 • 2018 ACR/ARHP Annual Meeting

    Inflammation in the Hippocampus Affects Insulin-like Growth Factor-1 Receptor Signaling and Contributes to Neurological Sequelae in Rheumatoid Arthritis

    Karin Andersson1, Caroline Wasén1, Lina Juzokaite1, Malin C Erlandsson1,2, Anna Stokowska3, Lovisa Leifsdottir4, Marcela Pekna3, Milos Pekny3, Kjell Olmarker5, Rolf Heckemann6,7,8, Marie Kalm9 and Maria I Bokarewa2, 1Department of rheumatology and inflammation research, University of Gothenburg, Gothenburg, Sweden, 2Rheumatology Clinic, Sahlgrenska University Hospital, Gothenburg, Sweden, 3Department of Clinical Neuroscience, University of Gothenburg, Gothenburg, Sweden, 4Rheumatology Clinics, Sahlgrenska University Hospital, Gothenburg, Sweden, 5Department of Medical Chemistry and Cell Biology, University of Gothenburg, Gothenburg, Sweden, 6Med Tech West at Sahlgrenska University Hospital, University of Gothenburg, Gothenburg, Sweden, 7Department of Medical Radiation Science, University of Gothenburg, Gothenburg, Sweden, 8Faculty of Medicine, Imperial College London, London, United Kingdom, 9Department of Pharmacology, University of Gothenburg, Gothenburg, Sweden

    Background/Purpose: The central nervous system is not the primary target in rheumatoid arthritis (RA). However, neuropsychiatric symptoms including pain, depression and anxiety are common and…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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