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Abstracts tagged "P. Gingivalis"

  • Abstract Number: 2430 • 2013 ACR/ARHP Annual Meeting

    Antibodies To Porphyromonas Gingivalis as An Etiological Clue To The Development Of Anti-Citrullinated Protein Antibody Positive Rheumatoid Arthritis

    Nastya Kharlamova1, Natalia Sherina1, Anne-Marie Quirke2, Kaja Eriksson3, Lena Israelsson4, Jan Potempa5, Patrick Venables6, Tulay Yucel-Lindberg3 and Karin Lundberg7, 1Rheumatology Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden, 2University of Oxford, Kennedy Institute of Rheumatology, Oxford, United Kingdom, 3Department of Dentistry, Karolinska Institutet, Stockholm, Sweden, 4Medicine, Rheumatology unit, Karolinska University Hospital, Karolinska Institute, Stockholm, Sweden, 5Microbiology Department, Jagiellonian University, Krakow, Poland, 6Kennedy Institute of Rheumatology, Oxford, United Kingdom, 7Rheumatology unit, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden

    Background/Purpose: Rheumatoid arthritis (RA) is characterized by the production of autoantibodies to citrullinated proteins (ACPA). Citrullinated proteins are generated by the actions of peptidyl arginine…
  • Abstract Number: 2409 • 2013 ACR/ARHP Annual Meeting

    Association Of High Serum Interleukin-23 Levels With Porphyromonas Gingivalis Antibodies In Patients With Early Rheumatoid Arthritis

    Sheila L. Arvikar1, Klemen Strle2, Deborah S. Collier3, Mark C. Fisher1, Toshihisa Kawai4, Jose U. Scher5 and Allen C. Steere6, 1Rheumatology, Allergy & Immunology, Massachusetts General Hospital, Boston, MA, 2Massachusetts General Hospital, Boston, MA, 3Rheumatology, Massachusetts General Hospital, Boston, MA, 4Forsyth Institute, Cambridge, MA, 5Department of Medicine, Division of Rheumatology, New York University School of Medicine, New York, NY, 6Medicine, Center for Immunolgy and Inflammatory Diseases, Massachusetts General Hospital, Harvard Medical School, Boston, MA

    Background/Purpose: Rheumatoid arthritis (RA) is associated with an increased frequency of periodontal disease (PD) and antibodies to P. gingivalis (Pg), a major periodontal pathogen. Both…
  • Abstract Number: 1378 • 2013 ACR/ARHP Annual Meeting

    Associations Of Periodontitis (PD) With Established Seropositive Rheumatoid Arthritis are Independent of Smoking and Other Risk Factors

    Ted R. Mikuls1, Jeffrey Payne2, Fang Yu3, Geoffrey M. Thiele4, Richard J. Reynolds5, Grant W. Cannon6, Jeffrey Markt7, David McGowan8, Gail S. Kerr9, Robert Redman10, Andreas M. Reimold11, Garth Griffiths12, Mark Beatty2, Shawneen Gonzalez2, Debra Bergman13, Bartlett C. Hamilton III14, Alan R. Erickson1 and James R. O'Dell15, 1Omaha VA Medical Center and University of Nebraska Medical Center, Omaha, NE, 2College of Dentistry, University of Nebraska Medical Center, Lincoln, NE, 3University of Nebraska Medical Center, Omaha, NE, 4Int Med/Sec of Rheum/Immun, Univ of Nebraska Med Ctr, Omaha, NE, 5Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL, 6Division of Rheumatology, Salt Lake City VA and University of Utah, Salt Lake City, UT, 7Otol-Head and Neck Surgery, University of Nebraska Medical Center, Omaha, NE, 8Dentistry, George E. Wahlen VA Medical Center, Salt Lake City, UT, 9Rheumatology, Washington DC VAMC, Georgetown and Howard University, Washington, DC, 10Dentistry, Washington DC VA, Georgetown and Howard University, Washington, DC, 11Rheumatology, Dallas VA and University of Texas Southwestern, Dallas, TX, 12Dentistry, Dallas VA and University of Texas Southwestern, Dallas, TX, 13Internal Medicine, University of Nebraska Medical Center, Omaha, NE, 14University of Nebraska Medical Center and Omaha VA Medical Center, Omaha, NE, 15Dept of Internal Medicine, University of Nebraska Medical Center, Omaha, NE

    Background/Purpose: Periodontitis (PD) has been proposed as a risk factor in RA.  Reports have suggested that this association may be due to confounding from smoking…
  • Abstract Number: 1360 • 2013 ACR/ARHP Annual Meeting

    Evaluation Of Biomarkers Involved In Periondontal Disease Including Porphyromonas Gingivalis Antibodies To Predict Response To Infliximab In Rheumatoid Arthritis Patients

    Mélanie Rinaudo-Gaujous1, Pierre Miossec2, Vincent Blasco-Baque3, Philippe Gaudin4, Christian Genin1, Thierry Thomas5, Stéphane Paul1 and Hubert Marotte6, 1Laboratory of Immunology and immunomonitoring, CIC CIE3 Inserm Vaccinology, GIMAP EA3064, Hôpital Nord, Saint-Etienne, France, 2Department of Clinical Immunology and Rheumatology, Immunogenomics and inflammation research unit, Lyon, France, 3Institute of Cardiovascular and Metabolic Diseases, CHU Rangueil, Toulouse, France, 4Rheumatology Department, CHU Hôpital Sud, Grenoble Teaching Hospital, Echirolles, France, 5INSERM U1059 and University Hospital, Saint-Etienne, France, 6LBTO INSERM U1059 University Jean Monnet, Saint-Etienne, France

    Background/Purpose: This study evaluates biological markers of rheumatoid arthritis (RA) severity including matrix metalloproteinase 3 (MMP-3) and Porphyromonas gingivalis (P. gingivalis) serology during infliximab therapy…
  • Abstract Number: 1369 • 2013 ACR/ARHP Annual Meeting

    Evaluation Of Porphyromona Gingivalis Serology In Rheumatoid Arthritis and Non-Rheumatoid Inflammatory Disease

    Mélanie Rinaudo-Gaujous1, Adeline Moreau1, Vincent Blasco-Baque2, Xavier Roblin3, Christian Genin1, Thierry Thomas4, Stéphane Paul1 and Hubert Marotte5, 1Laboratory of Immunology and immunomonitoring, CIC CIE3 Inserm Vaccinology, GIMAP EA3064, Hôpital Nord, Saint-Etienne, France, 2Institute of Cardiovascular and Metabolic Diseases, CHU Rangueil, Toulouse, France, 3Department of gastroenterology, Hôpital Nord, Saint-Etienne, France, 4INSERM U1059 and University Hospital, Saint-Etienne, France, 5INSERM U1059 and University Hospital, Hôpital Nord, Saint-Etienne, France

    Background/Purpose: Periodontal disease (PD) is associated mainly with rheumatoid arthritis (RA), but recent data suggest an association with ankylosing spondylitis (AS). Role of Porphyromonas gingivalis…
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