Abstracts tagged "P. Gingivalis"

Abstract Number: 2430 • 2013 ACR/ARHP Annual Meeting
Antibodies To Porphyromonas Gingivalis as An Etiological Clue To The Development Of Anti-Citrullinated Protein Antibody Positive Rheumatoid Arthritis
Nastya Kharlamova¹, Natalia Sherina¹, Anne-Marie Quirke², Kaja Eriksson³, Lena Israelsson⁴, Jan Potempa⁵, Patrick Venables⁶, Tulay Yucel-Lindberg³ and Karin Lundberg⁷, ¹Rheumatology Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden, ²University of Oxford, Kennedy Institute of Rheumatology, Oxford, United Kingdom, ³Department of Dentistry, Karolinska Institutet, Stockholm, Sweden, ⁴Medicine, Rheumatology unit, Karolinska University Hospital, Karolinska Institute, Stockholm, Sweden, ⁵Microbiology Department, Jagiellonian University, Krakow, Poland, ⁶Kennedy Institute of Rheumatology, Oxford, United Kingdom, ⁷Rheumatology unit, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden
Background/Purpose: Rheumatoid arthritis (RA) is characterized by the production of autoantibodies to citrullinated proteins (ACPA). Citrullinated proteins are generated by the actions of peptidyl arginine…
Abstract Number: 2409 • 2013 ACR/ARHP Annual Meeting
Association Of High Serum Interleukin-23 Levels With Porphyromonas Gingivalis Antibodies In Patients With Early Rheumatoid Arthritis
Sheila L. Arvikar¹, Klemen Strle², Deborah S. Collier³, Mark C. Fisher¹, Toshihisa Kawai⁴, Jose U. Scher⁵ and Allen C. Steere⁶, ¹Rheumatology, Allergy & Immunology, Massachusetts General Hospital, Boston, MA, ²Massachusetts General Hospital, Boston, MA, ³Rheumatology, Massachusetts General Hospital, Boston, MA, ⁴Forsyth Institute, Cambridge, MA, ⁵Department of Medicine, Division of Rheumatology, New York University School of Medicine, New York, NY, ⁶Medicine, Center for Immunolgy and Inflammatory Diseases, Massachusetts General Hospital, Harvard Medical School, Boston, MA
Background/Purpose: Rheumatoid arthritis (RA) is associated with an increased frequency of periodontal disease (PD) and antibodies to P. gingivalis (Pg), a major periodontal pathogen. Both…
Abstract Number: 1378 • 2013 ACR/ARHP Annual Meeting
Associations Of Periodontitis (PD) With Established Seropositive Rheumatoid Arthritis are Independent of Smoking and Other Risk Factors
Ted R. Mikuls¹, Jeffrey Payne², Fang Yu³, Geoffrey M. Thiele⁴, Richard J. Reynolds⁵, Grant W. Cannon⁶, Jeffrey Markt⁷, David McGowan⁸, Gail S. Kerr⁹, Robert Redman¹⁰, Andreas M. Reimold¹¹, Garth Griffiths¹², Mark Beatty², Shawneen Gonzalez², Debra Bergman¹³, Bartlett C. Hamilton III¹⁴, Alan R. Erickson¹ and James R. O'Dell¹⁵, ¹Omaha VA Medical Center and University of Nebraska Medical Center, Omaha, NE, ²College of Dentistry, University of Nebraska Medical Center, Lincoln, NE, ³University of Nebraska Medical Center, Omaha, NE, ⁴Int Med/Sec of Rheum/Immun, Univ of Nebraska Med Ctr, Omaha, NE, ⁵Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL, ⁶Division of Rheumatology, Salt Lake City VA and University of Utah, Salt Lake City, UT, ⁷Otol-Head and Neck Surgery, University of Nebraska Medical Center, Omaha, NE, ⁸Dentistry, George E. Wahlen VA Medical Center, Salt Lake City, UT, ⁹Rheumatology, Washington DC VAMC, Georgetown and Howard University, Washington, DC, ¹⁰Dentistry, Washington DC VA, Georgetown and Howard University, Washington, DC, ¹¹Rheumatology, Dallas VA and University of Texas Southwestern, Dallas, TX, ¹²Dentistry, Dallas VA and University of Texas Southwestern, Dallas, TX, ¹³Internal Medicine, University of Nebraska Medical Center, Omaha, NE, ¹⁴University of Nebraska Medical Center and Omaha VA Medical Center, Omaha, NE, ¹⁵Dept of Internal Medicine, University of Nebraska Medical Center, Omaha, NE
Background/Purpose: Periodontitis (PD) has been proposed as a risk factor in RA. Reports have suggested that this association may be due to confounding from smoking…
Abstract Number: 1360 • 2013 ACR/ARHP Annual Meeting
Evaluation Of Biomarkers Involved In Periondontal Disease Including Porphyromonas Gingivalis Antibodies To Predict Response To Infliximab In Rheumatoid Arthritis Patients
Mélanie Rinaudo-Gaujous¹, Pierre Miossec², Vincent Blasco-Baque³, Philippe Gaudin⁴, Christian Genin¹, Thierry Thomas⁵, Stéphane Paul¹ and Hubert Marotte⁶, ¹Laboratory of Immunology and immunomonitoring, CIC CIE3 Inserm Vaccinology, GIMAP EA3064, Hôpital Nord, Saint-Etienne, France, ²Department of Clinical Immunology and Rheumatology, Immunogenomics and inflammation research unit, Lyon, France, ³Institute of Cardiovascular and Metabolic Diseases, CHU Rangueil, Toulouse, France, ⁴Rheumatology Department, CHU Hôpital Sud, Grenoble Teaching Hospital, Echirolles, France, ⁵INSERM U1059 and University Hospital, Saint-Etienne, France, ⁶LBTO INSERM U1059 University Jean Monnet, Saint-Etienne, France
Background/Purpose: This study evaluates biological markers of rheumatoid arthritis (RA) severity including matrix metalloproteinase 3 (MMP-3) and Porphyromonas gingivalis (P. gingivalis) serology during infliximab therapy…
Abstract Number: 1369 • 2013 ACR/ARHP Annual Meeting
Evaluation Of Porphyromona Gingivalis Serology In Rheumatoid Arthritis and Non-Rheumatoid Inflammatory Disease
Mélanie Rinaudo-Gaujous¹, Adeline Moreau¹, Vincent Blasco-Baque², Xavier Roblin³, Christian Genin¹, Thierry Thomas⁴, Stéphane Paul¹ and Hubert Marotte⁵, ¹Laboratory of Immunology and immunomonitoring, CIC CIE3 Inserm Vaccinology, GIMAP EA3064, Hôpital Nord, Saint-Etienne, France, ²Institute of Cardiovascular and Metabolic Diseases, CHU Rangueil, Toulouse, France, ³Department of gastroenterology, Hôpital Nord, Saint-Etienne, France, ⁴INSERM U1059 and University Hospital, Saint-Etienne, France, ⁵INSERM U1059 and University Hospital, Hôpital Nord, Saint-Etienne, France
Background/Purpose: Periodontal disease (PD) is associated mainly with rheumatoid arthritis (RA), but recent data suggest an association with ankylosing spondylitis (AS). Role of Porphyromonas gingivalis…