Abstracts tagged "Outcome measures"

Abstract Number: 2118 • 2012 ACR/ARHP Annual Meeting
Validation of Prognostic Biomarkers for RA: Testing of 14-3-3 Eta According to the Omeract Soluble Biomarker Criteria
Walter P. Maksymowych¹, Désirée van der Heijde², R. Landewe³, George A. Wells⁴, Joan M. Bathon⁵, Clifton O. Bingham III⁶, Vivian P. Bykerk⁷, Mikkel Ostergaard⁸, Hilde B. Hammer⁹, Maarten Boers¹⁰, Paul Peter Tak¹¹, Oliver M. FitzGerald¹², Christopher T. Ritchlin¹³, Dafna D. Gladman¹⁴, Philip J. Mease¹⁵, Dirkjan van Schaardenburg¹⁶, Marina Backhaus¹⁷, Bernard Combe¹⁸, Gianfranco Ferraccioli¹⁹ and Anthony Marotta²⁰, ¹Department of Medicine, University of Alberta, Edmonton, AB, Canada, ²Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ³Division of Clinical Immunology and Rheumatology, Academic Medical Center / University of Amsterdam, Amsterdam, Netherlands, ⁴Epidemiology & Community Med, Univ of Ottawa Faculty of Med, Ottawa, ON, Canada, ⁵Columbia University, New York, NY, ⁶Rheumatology, Johns Hopkins University, Baltimore, MD, ⁷Rheumatology, Hospital for Special Surgery, New York, NY, ⁸Dept of Rheumatology RM, Copenhagen University Hospital, Glostrup, Denmark, ⁹Dept of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, ¹⁰Epidemiology & Biostatistics, VU University Medical Center, Amsterdam, Netherlands, ¹¹Clinical Immunology and Rheumatology, Academic Medical Center/University of Amsterdam, Amsterdam, Netherlands, ¹²Rheumatology, Dublin Academic Medical Centre, St. Vincent's University Hospital, Dublin, Ireland, ¹³Allergy, Immunology and Rheumatology, University of Rochester, Rochester, NY, ¹⁴Division of Rheumatology, Toronto Western Hospital and University of Toronto, Toronto, ON, Canada, ¹⁵Swedish Rheumatology Research Group, Seattle, WA, ¹⁶Jan van Breemen Research Institute | Reade, Amsterdam, Netherlands, ¹⁷Rheumatology/Immunology, Charite University Hospital, Berlin, Germany, ¹⁸Rheumatology, Hopital Lapeyronie, Montpellier, France, ¹⁹Division of Rheumatology, Catholic University of the Sacred Heart, Rome, Italy, ²⁰Augurex Life Sciences Corp, North Vancouver, BC, Canada
Background/Purpose: The OMERACT soluble biomarker sub-committee has published validation criteria related to truth, discrimination and feasibility for biomarkers reflecting structural damage1. The large majority of…
Abstract Number: 869 • 2012 ACR/ARHP Annual Meeting
Concepts Which Determine Health in a Positive Way Are Important to People with Rheumatoid Arthritis and Are Covered by Some Patient-Reported Outcome Instruments
Mona Dür¹, Michaela Coenen², Josef S. Smolen³ and Tanja A. Stamm⁴, ¹Internal Medicine III Division of Rheumatology, Medical University of Vienna, Vienna, Austria, ²Department of Medical lnformatics, Biometry and Epidemiology, Research Unit for Biopsychosocial Health, Ludwig-Maximilians-University, Munich, Germany, ³Division of Rheumatology, Department of Internal Medicine III,, Medical University of Vienna and Hietzing Hospital, Vienna, Austria, ⁴Rheumatology, Medical University of Vienna, Vienna, Austria
Background/Purpose: Rheumatoid arthritis is a chronic autoimmune disease that has a major impact on functioning, health and well-being. Concepts which determine health in a positive…
Abstract Number: 2100 • 2012 ACR/ARHP Annual Meeting
Relative, Reliability-Adjusted Diagnostic Test Accuracy of Erosion Detection Between Magnetic Resonance Imaging and Radiography in Rheumatoid Arthritis
Ruben Tavares¹, Naveen Parasu², Karen Finlay², Erik Jurriaans², Hao Wu¹, Karen A. Beattie³, Maggie Larche⁴, Lawrence E. Hart⁵, William G. Bensen⁶, Raja S. Bobba⁴, Alfred A. Cividino³, Colin E. Webber⁷, Jean-Eric Tarride⁸ and Jonathan D. Adachi⁹, ¹McMaster University, Hamilton, ON, Canada, ²Radiology, Hamilton Health Sciences, Hamilton, ON, Canada, ³Medicine, McMaster University, Hamilton, ON, Canada, ⁴Rheumatology, McMaster University, Hamilton, ON, Canada, ⁵Medicine (Rheumatology), St. Joseph's Health Care, Hamilton, ON, Canada, ⁶Department of Medicine, Division of Rheumatology, St. Joseph's Hospital and McMaster University, Hamilton, ON, Canada, ⁷Department of Nuclear Medicine, Hamilton Health Sciences, Hamilton, ON, Canada, ⁸Clinical Epidemiology and Biostatistics (CE&B) and Economics, Programs for Assessment of Technology in Health (PATH) Research Institute, Hamilton, ON, Canada, ⁹St Joseph's Healthcare Hamilton, Hamilton, ON, Canada
Background/Purpose: In rheumatoid arthritis (RA), erosion detection on radiography (X-ray) compared to magnetic resonance imaging (MRI) is characterized by low sensitivity and high specificity. This…
Abstract Number: 710 • 2012 ACR/ARHP Annual Meeting
Optical Density Measure of the Papillary Dermis Discriminates As Abnormal Clinically Uninvolved Skin in Systemic Sclerosis and Correlates with Severity of Skin Thickness
Giuseppina Abignano¹, Sibel Z. Aydin², Concepcion Castillo-Gallego³, Daniel Woods⁴, Adam Meekings⁵, Dennis McGonagle⁶, Paul Emery⁷ and Francesco Del Galdo⁸, ¹Chapel Allerton Hospital Leeds Insitute of Molecular medicine, Division of Rheumatic and Musculoskeletal Disease, University of Leeds, Leeds Institute of Molecular Medicine and LMBRU, Leeds, United Kingdom, ²Unit of Rheumatology, Medeniyet University, Goztepe Training and Research Hospital, Istanbul, Turkey, ³Rheumatology, Hospital La Paz - IdiPaz, Madrid, Spain, ⁴Michelson Diagnostics Ltd, Kent, United Kingdom, ⁵Michelson Diagnostics Ltd, Kent, United Kingdom, Kent, United Kingdom, ⁶Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, ⁷Division of Rheumatic and Musculoskeletal Disease, University of Leeds, Leeds Institute of Molecular Medicine and LMBRU, Leeds, United Kingdom, ⁸Musculoskeletal Diseases, University of Leeds, Leeds Institute of Molecular Medicine and LMBRU, Leeds, United Kingdom
Background/Purpose: Skin involvement in systemic sclerosis (SSc) is often primary outcome in clinical trials and its severity inversely correlates with prognosis. Nevertheless, an objective quantitative…
Abstract Number: 2064 • 2012 ACR/ARHP Annual Meeting
Regular Measure of Disease Activity During the Routine Care of Rheumatoid Arthritis Patients Involves Some Extra Work but Positive Results
Lissiane K. N. Guedes¹, Ana Cristina Medeiros Ribeiro², Karina Rossi Bonfiglioli³, Diogo Domiciano¹, Carolina Reither Vizioli¹, Gilmara Franco da Cunha¹, Andressa Silva Abreu¹, Filipi M. Mello¹, Ana Luiza de Aguiar Foelkel⁴, Celio R. Gonçalves¹ and Ieda Laurindo¹, ¹Rheumatology, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, ²Reumatologia, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, ³Rheumatology Division, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, ⁴Rheumatology, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil
Background/Purpose: According to treat to target recommendations the use of validated composite measures of disease activity, which include joint assessments, is needed in routine clinical…
Abstract Number: 631 • 2012 ACR/ARHP Annual Meeting
Peripheral Neuropathy Due to Systemic Lupus Erythematosus (SLE) Itself: Incidence, Disease Risk Factors and Outcome
Simone Fargetti¹, Samuel K. Shinjo², Sandra G. Pasoto¹, Ana L. Calich¹, Eloisa Bonfa³ and Eduardo F. Borba¹, ¹Rheumatology Division, University of Sao Paulo, Sao Paulo, Brazil, ²Rheumatology Division, Faculdade de Medicina da Universidade de São Paulo, Sao Paulo, Brazil, ³Rheumatology Division, University of São Paulo, Sao Paulo, Brazil
Background/Purpose: Peripheral neuropathy (PN) solely attributable to SLE itself is difficult to define since most of these patients are exposed to several other conditions that…
Abstract Number: 2068 • 2012 ACR/ARHP Annual Meeting
Is There a Difference in Rheumatology Patient Reported Outcomes When Measured At Home Versus the Clinic Setting?
C.J. Inman¹, Frederick Wolfe² and Kaleb Michaud³, ¹Pediatric Administration, University of Utah, Salt Lake City, UT, ²National Data Bank for Rheumatic Diseases, Wichita, KS, ³Rheumatology, National Data Bank for Rheumatic Diseases & University of Nebraska Medical Center, Omaha, NE
Background/Purpose: Registries have become a common tool for collecting patient-centered outcome measures. Clinical effectiveness research may be improved if data from multiple registries could be…
Abstract Number: 563 • 2012 ACR/ARHP Annual Meeting
In Ankylosing Spondylitis, a Decrease in MRI Spinal Inflammation Predicts Improvement in Spinal Mobility Independently of Patient Reported Symptomatic Improvement
Pedro Machado¹, Robert Landewé², Jürgen Braun³, Xenofon Baraliakos⁴, Kay-Geert A. Hermann⁵, Benjamin Hsu⁶, Daniel Baker⁷ and Désirée van der Heijde¹, ¹Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ²Clinical Immunology & Rheumatology, Academic Medical Center, University of Amsterdam and Atrium Medical Center, Heerlen, Netherlands, ³PsAID taskforce, EULAR, Zurich, Switzerland, ⁴Rheumatology, Rheumazentrum Ruhrgebiet, Herne, Germany, ⁵Radiology, Charité Universitätsmedizin Berlin, Campus Mitte, Berlin, Germany, ⁶Janssen Research & Development, LLC., Spring House, PA, ⁷Research and Development, Centocor Inc., Malvern/Philadelphia, PA
Background/Purpose: It has been previously shown that spinal mobility in ankylosing spondylitis (AS) is associated with the level of inflammation of the spine. However an…
Abstract Number: 2029 • 2012 ACR/ARHP Annual Meeting
Reliability of Scoring a Disease Damage Measure for Juvenile Localized Scleroderma
Kathryn S. Torok¹, Suzanne C. Li², Christina Kelsey³, Mara L Becker⁴, Fatma Dedeoglu⁵, Robert C. Fuhlbrigge⁶, Gloria Higgins⁷, Sandy D. Hong⁸, Maria F. Ibarra⁹, Ronald Laxer¹⁰, Thomas G. Mason II¹¹, Marilynn G. Punaro¹², Elena Pope¹³, C. Egla Rabinovich¹⁴ and Katie G. Stewart¹², ¹Pediatric Rheumatology, Scleroderma Center of Pittsburgh, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA, ²Pediatrics, Joseph M Sanzari Children's Hospital, Hackensack University Medical Center, Hackensack, NJ, ³Pediatric Rheumatology, Univ of Pittsburgh Med Ctr, Pittsburgh, PA, ⁴Clinical Pharmacology and Rheumatology, Children's Mercy Hospital, Kansas City, MO, ⁵Division of Immunology, Boston Children's Hospital, Boston, MA, ⁶Pediatric Rheumatology, Childrens Hospital, Boston, MA, ⁷Pediatric Rheumatology NATIONWIDE CHILDRENS HOSPITAL, PRCSG-Cincinnati Children's Hospital Medical Center, Columbus, OH, ⁸Pediatrics-Rheumatology, U of Iowa Children's Hosp, Iowa City, IA, ⁹Pediatric Rheumatolgy, Children's Mercy Hospital, Kansas City, MO, ¹⁰Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada, ¹¹Rheumatology, Mayo Clinic Rochester, Rochester, MN, ¹²Pediatric Rheumatology, Texas Scottish Rite Hospital, Dallas, TX, ¹³Dermatology, The Hospital for Sick Children, Toronto, ON, Canada, ¹⁴Pediatric Rheumatology, Duke University Medical Center, Durham, NC
Background/Purpose: . In order to more accurately capture disease activity and damage in juvenile Localized Scleroderma (jLS) and to develop an accepted outcome measure for…
Abstract Number: 397 • 2012 ACR/ARHP Annual Meeting
Assessment of Global Disease Activity in Rheumatoid Arthritis Patients Monitored in the Measurement of Efficacy of Treatment in the Era of Rheumatology Database: The patient’s Versus the rheumatologist’s Opinion
E. Gvozdenovic¹, R. Koevoets¹, R. Wolterbeek², Désirée van der Heijde³, T.W.J. Huizinga¹, C.F. Allaart¹ and Robert B. M. Landewé⁴, ¹Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ²Biostatistics, Leiden University Medical Center, Leiden, Netherlands, ³Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ⁴Academic Medical Center/University of Amsterdam & Atrium Medical Center, Amsterdam, Netherlands
Background/Purpose: Disagreement on disease activity between rheumatoid arthritis (RA) patients and rheumatologists may influence treatment decisions and compliance. The aim is to compare the physician's…
Abstract Number: 2037 • 2012 ACR/ARHP Annual Meeting
Poor Quality of Gout Care Is Strongly Associated with Higher Gout-Related Health Care Utilization
Jasvinder A. Singh¹ and Joshua Richman², ¹Department of Medicine, University of Alabama, Tuscaloosa, AL, ²Biostatistics, UAB School of Medicine, Birmingham, AL
Background/Purpose: Proponents of improving quality of gout care have suggested various gout quality indicators, but no study to date has shown the link between…
Abstract Number: 403 • 2012 ACR/ARHP Annual Meeting
The Impact of Reaching Low Disease Activity in the First Year On Future Disability and Damage in Patients with Early Rheumatoid Arthritis
Pooneh Akhavan¹, George A. Tomlinson², Paul R. Fortin³ and Claire Bombardier¹, ¹Rheumatology, University of Toronto, Toronto, ON, Canada, ²Dept of Medicine/Rheumatology, Toronto General Hospital, Toronto, ON, Canada, ³Medicine, Centre de Recherche du Chu de Québec et Université Laval, Quebec City, QC, Canada
Background/Purpose: Remission has been proposed as the goal of treatment in patients with early rheumatoid arthritis (RA) by current clinical practice guidelines. Remission is ideal…

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Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. Academic institutions, private organizations and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part a scientific presentation or presentation of additional new information that will be available at the time of the meeting) is under embargo until Saturday, November 11, 2023.

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