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Abstracts tagged "Outcome measures"

  • Abstract Number: 2536 • 2013 ACR/ARHP Annual Meeting

    Lupus Impact Tracker Is Responsive To Changes In Physician Assessed Disease Status By Systemic Lupus Erythematosus Responder Index

    Hervé Devilliers1,2, Mark Kosinski3, Cindy Garris4 and Meenakshi Jolly5, 1Clinical investigation and clinical epidemiology center (INSERM CIE01), Dijon, France, 2Internal medicine and systemic disease unit, Dijon University Hospital, Dijon, France, 3QualityMetric Inc, Lincoln, RI, 4US Health Outcomes, GlaxoSmithKline R&D, Research Triangle Park, NC, 5Rheumatology, Rush University Medical Center, Chicago, IL

    Background/Purpose: Lupus Impact Tracker (LIT) is a 10-item patient reported outcome tool to measure the impact of Systemic Lupus Erythematosus (SLE) or its treatment on…
  • Abstract Number: 1351 • 2013 ACR/ARHP Annual Meeting

    A Comparison Of The Clinical Effectiveness Of Treatment Strategies For Active RA Patients : Using a Prospective Biologic Registry (BIOPSY) and an RA Specific Cohort (KORONA)

    Yoon-Kyoung Sung1,2, Soo-Kyung Cho1,2, Chan-Bum Choi3,4, Soyoung Won5, So-Young Bang6, Hoon-Suk Cha7, Jung-Yoon Choe8, Won Tae Chung9, Seung-Jae Hong10, Jae-Bum Jun4, Hyoun Ah Kim11, Jinseok Kim12, Seong-Kyu Kim8, Tae-Hwan Kim4, Hye-Soon Lee13, Jaejoon Lee7, Jisoo Lee14, Shin-Seok Lee15, Sung Won Lee16, Yeon-Ah Lee10, Seong-Su Nah17, Chang-Hee Suh18, Dae-Hyun Yoo4, Bo Young Yoon19 and Sang-Cheol Bae1,2, 1Department of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea, 2Department of Rheumatology, Clinical Research Center for Rheumatoid Arthritis (CRCRA), Seoul, South Korea, 3Department of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Clinical Research Center for Rheumatoid Arthritis (CRCRA), Seoul, South Korea, 4Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea, 5Clinical Research Center for Rheumatoid Arthritis (CRCRA), Seoul, South Korea, 6Hanyang University Guri Hospital, Guri, South Korea, 7Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea, 8Catholic University of Daegu School of Medicine, Daegu, South Korea, 9Division of Rheumatology, Department of Internal Medicine, Dong-A University Hospital, Busan, South Korea, 10Division of Rheumatology, Department of Internal Medicine, Kyung Hee University, Seoul, South Korea, 11Ajou University Hospital, Suwon, South Korea, 12Division of Rheumatology, Internal Medicine, Jeju National University Hospital, Jeju, Korea, South Korea, 13Department of Rheumatology, Hanyang University Guri Hospital, Guri, South Korea, 14Internal Medicine, Ewha Womans University Mokdong Hospital, Seoul, South Korea, 15Rheumatology, Chonnam National University Medical School and Hospital, Gwangju, South Korea, 16Rheumatology, Dong-A University Hospital, Busan, South Korea, 17Division of Rheumatology, Department of Internal Medicine, Soonchunhyang University Cheonan Hospital, Cheonan, South Korea, 18Department of Rheumatology, Ajou University Hospital, Suwon, South Korea, 19Inje University Ilsan Paik Hospital, Goyang, South Korea

    Background/Purpose: The results from RCTs may not be generalizable to clinical practice because of their inclusion and exclusion criteria. Instead, observational cohorts and registries might…
  • Abstract Number: 2292 • 2013 ACR/ARHP Annual Meeting

    Factors Affecting The Discrepancy Between Physician and Patient Global Assessment Of Disease Activity In Early and Established Rheumatoid Arthritis Patients- Results From The Ontario Best Practices Initiative

    Pooneh Akhavan1, Binu Jacob2, Edward C. Keystone3,4, Xiuying Li5, J. Carter Thorne6 and Claire Bombardier7, 1Medicine, Early Rheumatoid Arthritis Program, Mount Sinai Hospital and University of Toronto, Toronto, ON, Canada, 2University Health Network, Toronto General Research Institute, Toronto, ON, Canada, 3Rebecca MacDonald Centre for Arthritis and Autoimmune Disease, Mount Sinai Hospital, Toronto, ON, Canada, 4University of Toronto/Mount Sinai Hospital, Toronto, ON, Canada, 5Clinical Decision Making and Health Care, University Health Network, Toronto, ON, Canada, 6Southlake Regional Health Centre, Newmarket, ON, Canada, 7Rheumatology, University of Toronto, Toronto, ON, Canada

    Background/Purpose: Discrepancy between patient (PGA) and physician (MDGA) global assessments in Rheumatoid Arthritis (RA) can adversely affect therapeutic decisions. The pattern of PGA and MDGA,…
  • Abstract Number: 1264 • 2013 ACR/ARHP Annual Meeting

    Evaluation Of Quality Indicators and Disease Damage In Childhood-Onset Systemic Lupus Erythematosus Patients

    Julia G. Harris1,2, Kristyn I. Maletta3, Evelyn M. Kuhn3 and Judyann C. Olson1,2, 1Medical College of Wisconsin, Milwaukee, WI, 2Children's Hospital of Wisconsin, Milwaukee, WI, 3National Outcomes Center, Children's Hospital of Wisconsin, Milwaukee, WI

    Background/Purpose:   Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that can affect virtually every organ system and may lead to significant morbidities.  A…
  • Abstract Number: 2300 • 2013 ACR/ARHP Annual Meeting

    Rheumatologists Who Are Consistently Using An Objective Outcome Instrument Do Not “Treat To Target” In a Real World Setting

    Gary Craig1,2, Howard Kenney1,2, Keith Knapp2 and Sergio Schwartzman3, 1Arthritis Northwest PLLC., Spokane, WA, 2T3 JointMan LLC., Spokane, WA, 3Rheumatology, Hosp for Special Surgery, New York, NY

    Background/Purpose: The public database JointManTMwas launched January 2012 with a mission to provide a practical outcome tool to manage patients with RA in a clinical…
  • Abstract Number: 968 • 2013 ACR/ARHP Annual Meeting

    Success Of Educational Intervention In Improving The Management Of Rheumatoid Arthritis

    Nimish Mehta and Ronald Viggiani, Medscape, LLC, New York, NY

    Background/Purpose: In many patients with rheumatoid arthritis (RA), the disease is not adequately controlled and only a minority of patients attain the goal of consistent…
  • Abstract Number: 2238 • 2013 ACR/ARHP Annual Meeting

    Comparison Of The Long-Term Outcome For Rheumatoid Arthritis Patients With  persistent Moderate Disease Activity Or Disease Remission During The First Year After Diagnosis: Data From The Espoir Cohort

    Bernard Combe1, Isabelle Logeart2, M. Belkacemi3, S Dadoun4, Jean-Pierre Daurès5 and Maxime Dougados6, 1Rheumatology, Lapeyronie Hospital, Montpellier I university, Montpellier, France, 2Pfizer, Paris, France, 3CHRU Montpellier, Montpellier, France, 4Paris-Pitié Salpêtrière University Hospital, Paris, France, 5Service BESPIM, CHU, Nimes, France, 6Rheumatology B Department, Paris-Descartes University, Cochin Hospital, Paris, France

    Background/Purpose: The Treat to Target and EULAR recommendations highlighted the need for achieving and maintaining remission in patients with early RA. We investigated if early…
  • Abstract Number: 763 • 2013 ACR/ARHP Annual Meeting

    The Risk Of Myocardial Infarction In Systemic Sclerosis: A Population-Based Cohort Study

    Iman Hemmati1, Hyon K. Choi2,3, Kamran Shojania3,4, Eric C. Sayre3 and J. Antonio Avina-Zubieta3,5, 1Deparment of Medicine and Rheumatology, University of British Columbia, Vancouver, BC, Canada, 2Section of Rheumatology and the Clinical Epidemiology Unit, Boston University School of Medicine, Boston, MA, 3Arthritis Research Centre of Canada, Richmond, BC, Canada, 4Rheumatology, University of British Columbia, Vancouver, BC, Canada, 5Rheumatology, Arthritis Research Centre of Canada, Richmond, BC, Canada

    Background/Purpose: An increased risk of premature atherosclerosis has been well described in patients with rheumatoid arthritis and systemic lupus erythematosus. However, there is limited data…
  • Abstract Number: 2245 • 2013 ACR/ARHP Annual Meeting

    Predictive Validity Of Low Disease Activity Using Patient Reported Measures On Long-Term Outcomes In Early Rheumatoid Arthritis- Results From Study Of New Onset Rheumatoid Arthritis and Ontario Best Practices Initiative

    Pooneh Akhavan1, Binu Jacob2, Paul R. Fortin3, George A. Tomlinson4 and Claire Bombardier5,6, 1Medicine, Mount Sinai Hospital/University of Toronto, Toronto, ON, Canada, 2University Health Network, Toronto General Research Institute, Toronto, ON, Canada, 3University of Laval, Quebec, QC, Canada, 4Dept of Medicine/Rheumatology, Toronto General Hospital, Toronto, ON, Canada, 5Rheumatology, University of Toronto, Toronto, ON, Canada, 6Division of rheumatology and Department of Health Policy, Management, and Evaluation, University Health Network, Toronto, ON, Canada

    Background/Purpose: Patient reported outcome measures (PROM) are used in routine practice for assessment of disease activity. They have been shown to correlate well with other…
  • Abstract Number: 482 • 2013 ACR/ARHP Annual Meeting

    Methotrexate Use At Infliximab Initiation and Impact On Treatment Outcomes: An Analysis From A Canadian Registry

    Denis Choquette1, J. Carter Thorne2, John T. Kelsall3, Michel Zummer4, Michael Starr5, Maqbool K. Sheriff6, William G. Bensen7, Andrew Chow8, Philip Baer9, Emmanouil Rampakakis10, John S. Sampalis10, Francois Nantel11, Allen J. Lehman12, Susan M. Otawa12 and May Shawi13, 1Rheumatology, Institut de rhumatologie de Montréal (IRM), Montréal, QC, Canada, 2Southlake Regional Health Centre, Newmarket, ON, Canada, 3Mary Pack Arthritis Centre, Vancouver, Vancouver, BC, Canada, 4Rheumatology, Ch Maisonneuve-Rosemont, Montreal, QC, Canada, 5Montreal General Hospital, Montreal, QC, Canada, 6Nanaimo Regional General Hospital, Nanaimo, BC, Canada, 7Department of Medicine, Division of Rheumatology, Clinical Professor, McMaster University, Hamilton, ON, Canada, 8University of Toronto, McMaster University, Credit Valley Rheumatology, Mississauga, ON, Canada, 9Private Practice, Scarborough, ON, Canada, 10JSS Medical Research, Montreal, QC, Canada, 11Janssen Inc., Toronto, ON, Canada, 12Medical Affairs, Janssen Inc., Toronto, ON, Canada, 13Medical Affairs, Janssen Canada Inc, Toronto, ON, Canada

    Background/Purpose: Clinical trials of anti-TNF therapies have shown that concurrent methotrexate (MTX) therapy enhances the efficacy of infliximab (IFX)1. Data on the benefits of combination…
  • Abstract Number: 2247 • 2013 ACR/ARHP Annual Meeting

    Response To a Sleep Query On The Multi-Dimensional Health Assessment Questionnaire (MDHAQ) Is Related To Levels Of Disease Activity

    Martin J. Bergman1,2, Sapna Sangani3, Isabel Castrejón4 and Theodore Pincus4, 1Medicine, Drexel University College of Medicine, Philadelphia, PA, 2Taylor Hospital, Ridley Park, PA, 3Medicine, Mercy Catholic Medical Center, Lansdowne, PA, 4Rheumatology, Rush University Medical Center, Chicago, IL

    Background/Purpose:  Patients with rheumatoid arthritis (RA) often report fatigue, but a possible impact of disease on sleep and/or on disease activity are poorly characterized. We…
  • Abstract Number: 453 • 2013 ACR/ARHP Annual Meeting

    Impact Of Inadequate Adherence On Clinical Outcomes: Results From The Biologics In Rheumatoid Arthritis Genetics and Genomics Study Syndicate Cohort

    James Bluett1, Catharine Morgan1, Layla Thurston2, Darren Plant1, Ann W. Morgan3, Anthony G. Wilson4, John Isaacs5, Kimme L. Hyrich1, Lis Cordingley1 and Anne Barton1, 1Arthritis Research UK Epidemiology Unit, The University of Manchester, Manchester, United Kingdom, 2Manchester Medical School, The University of Manchester, Manchester, United Kingdom, 3NIHR-Leeds Musculoskeletal Biomedical Research Unit and Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, 4Department of Infection and Immunity, University of Sheffield, Sheffield, United Kingdom, 5National Institute for Health Research, Newcastle Biomedical Research Centre, Newcastle Hospitals Foundation Trust and Newcastle University, Newcastle Upon Tyne, United Kingdom

    Background/Purpose: Biologic therapy has revolutionised patient prognosis in rheumatoid arthritis (RA). In the UK, continuing biologic therapy requires a sustained response as determined by the…
  • Abstract Number: 2135 • 2013 ACR/ARHP Annual Meeting

    Musculoskeletal Pain Explains Differences In Function At Time Of Surgery In Black TKR and THR Patients

    Anthony Porter1, Wenjun Li2, Leslie R. Harrold1, Milagros Rosal3, Philip Noble4, David Ayers2, Patricia D. Franklin2 and Jeroan Allison5, 1University of Massachusetts Medical School, Worcester, MA, 2Orthopedics and Physical Rehabilitation, University of Massachusetts Medical School, Worcester, MA, 3Preventive and Behavioral Medicine, University of Massachusetts Medical School, Worcester, MA, 4Baylor College of Medicine, Houston, TX, 5Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, MA

    Background/Purpose: The existence of racial disparities in total knee (TKR) and total hip (THR) replacement outcomes is well established but not well understood.  The burden…
  • Abstract Number: 429 • 2013 ACR/ARHP Annual Meeting

    Sustained Clinical Efficacy After Multiple Courses of Rituximab in Rheumatoid Arthritis Patients With Inadequate Response to Tumour Necrosis Factor Inhibitors: 2-Year Data From the Repeat (Repeated Courses in Routine Clinical Practice) Study

    Catalin Codreanu1, Ioan Ancuta2 and Ruxandra Ionescu3, 1Rheumatology, “Dr. I. Stoia” Center for Rheumatic Diseases, Bucharest, Romania, 2“Dr. I. Cantacuzino” Hospital, Bucharest, Romania, 3Internal Medicine, Clinic Hospital Sf. Maria, Bucharest, Romania

    Background/Purpose: In the last decade, biologic therapy changed dramatically treatment options for rheumatoid arthritis (RA). However, a significant number of patients failed to maintain the…
  • Abstract Number: 2136 • 2013 ACR/ARHP Annual Meeting

    Does Functional Gain and Pain Relief After TKR and THR Differ By Patient Obese Status?

    Wenjun Li1, Leslie R. Harrold2, Jeroan Allison3, Courtland Lewis4, Thomas Bowen5, Patricia D. Franklin1 and David Ayers1, 1Orthopedics and Physical Rehabilitation, University of Massachusetts Medical School, Worcester, MA, 2University of Massachusetts Medical School, Worcester, MA, 3Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, MA, 4Hartford Hospital, Hartford, CT, 5Geisinger, Danville, PA

    Background/Purpose: Obesity is an important predictor of functional status and pain after total knee (TKR) and total hip (THR) replacement. However, variations in pre-post TKR…
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