Abstracts tagged "Outcome measures"

Abstract Number: 0313 • ACR Convergence 2020
Swollen Joints but Not Tender Joints Are Associated with Ultrasound Power Doppler Synovitis in Very Early DMARD Naive Psoriatic Arthritis
Sayam Dubash¹, Oras Alabas¹, Xabier Michelena¹, Leticia Garcia-Montoya¹, Gabriele De Marco², Mira Merashli³, Richard Wakefield¹, Philip Helliwell⁴, Ai Lyn Tan¹, Dennis McGonagle¹, Paul Emery⁵ and Helena Marzo-Ortega¹, ¹The University of Leeds, Leeds Institute for Rheumatic and Musculoskeletal Medicine, NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals Trust, Leeds, UK, Leeds, United Kingdom, ²The University of Leeds, Leeds Institute for Rheumatic and Musculoskeletal Medicine, NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals Trust, Leeds, UK, Treviglio, Italy, ³The University of Leeds, Leeds Institute for Rheumatic and Musculoskeletal Medicine, NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals Trust, Leeds, UK, Beirut, Lebanon, ⁴Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, ⁵Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds and NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals NHS Trust, Leeds, UK, Leeds, United Kingdom
Background/Purpose: Clinical tender and swollen joint counts are used for biologic drug eligibility and clinical trial inclusion criteria. Ultrasonography (US) adds to clinical examination as…
Abstract Number: 0631 • ACR Convergence 2020
Clinical Manifestations and Outcomes in DMARD-Naïve Patients with Chronic Chikungunya Arthritis
Nicolle Medina-Cintrón¹, Idali Martínez¹, Naydi Pérez-Ríos², Yaritza Berríos-López² and Luis Vilá³, ¹University of Puerto Rico Medical Science Campus, San Juan, Puerto Rico, ²University of Puerto Rico Medical Sciences Campus, San Juan, Puerto Rico, ³University of Puerto Rico Medical Sciences Campus, San Juan
Background/Purpose: Chikungunya virus (CHIKV) is characterized by fever, maculopapular rash, and severe polyarthralgia and polyarthritis. Up to 80% of affected individuals may develop chronic CHIKV…
Abstract Number: 1119 • ACR Convergence 2020
Association of Primary Insurance Status on Bilateral Knee Arthroplasty Utilization and Complications: A United States Nationwide Analysis
Bella Mehta¹, Kaylee Ho², Jennifer Bido³, Stavros Memtsoudis³, Michael Parks⁴, Linda Russell⁵, Susan Goodman¹ and Said Ibrahim⁶, ¹Hospital for Special Surgery, Weill Cornell Medicine, New York, NY, ²Weill Cornell Medicine, New York, ³Hospital for Special Surgery, New York, ⁴Hospital for Special Surgery, Weill Cornell Medicine, New York, ⁵Hospital for Special Surgery/Weill Cornell Medicine, New York, NY, ⁶Weill Cornell Medicine, Cleveland, OH
Background/Purpose: In patients with end-stage bilateral knee osteoarthritis, treatment options include either a staged total knee arthroplasty (TKA) procedure, often with a few months in…
Abstract Number: 1645 • ACR Convergence 2020
Placebo Group Responses in Clinical Trials of Patients with Osteoarthritis: Data from the Tanezumab Development Program
Luana Colloca¹, Robert Dworkin², John Farrar³, Leslie Tive⁴, Ed Whalen⁵, Jerry Yang⁴, Lars Viktrup⁶, Mark Brown⁷, Christine West⁷ and Kenneth Verburg⁸, ¹University of Maryland, Baltimore, ²University of Rochester School of Medicine and Dentistry, Rochester, NY, ³University of Pennsylvania, Philadelphia, PA, ⁴Pfizer Inc, New York, NY, ⁵Pfizer Inc, New York, ⁶Eli Lilly and Company, Indianapolis, IN, ⁷Pfizer Inc, Groton, CT, ⁸Pfizer Inc, Groton
Background/Purpose: The level of placebo group response in clinical trials for chronic pain conditions is a concern for the development of novel analgesics1. Here, we…
Abstract Number: 1887 • ACR Convergence 2020
Spinal Mobility and Function: How Closely Do They Associate in Axial Spondyloarthropathy?
Sinead Maguire¹, Phil Gallagher² and Finbar O'Shea¹, ¹St James' Hospital, Dublin, Ireland, ²St Vincents University Hospital, UCD, Dublin, Ireland
Background/Purpose: Axial spondyloarthropathy (axSpA) is a form of inflammatory arthritis affecting the axial skeleton. Persistent disease activity can result in restricted spinal mobility over time,…
Abstract Number: 0119 • ACR Convergence 2020
Fracture Liaison Service at an Academic Center with an Open Health System: 30-month Outcomes
Donna Jose¹, Micah Yu², Karina Torralba³, Christina Downey⁴, Justin Dunn⁵ and Vinicius Cabido⁵, ¹Loma Linda University Medical Center, Ontario, CA, ²Loma Linda University Medical Center, Loma Linda, CA, ³Loma Linda University School of Medicine, Redlands, CA, ⁴Loma Linda University Medical Center, Redlands, CA, ⁵Loma Linda University Medical Center, Loma Linda
Background/Purpose: Osteoporosis causes significant morbidity, mortality and healthcare burden. There continues to be a care gap in osteoporosis recognition, treatment and prevention. Several healthcare systems…
Abstract Number: 0321 • ACR Convergence 2020
Outcome Measures in Psoriatic Arthritis Registries Are Very Heterogeneous: A Systematic Literature Review of 27 Registries, or 16183 Patients
Krystel Aouad¹, Georgia Moysidou¹, Antsa Rakotozafiarison¹, Bruno Fautrel² and Laure Gossec¹, ¹Sorbonne University, INSERM; Pitié-Salpêtrière Hospital, Paris, Ile-de-France, France, ²Sorbonne University, INSERM, IPLES; Pitié-Salpêtrière Hospital, Paris, Ile-de-France, France
Background/Purpose: Psoriatic arthritis (PsA) is a multidimensional inflammatory disease for which multiple outcome measures can be used, to assess disease activity e.g. through composite scores,…
Abstract Number: 0633 • ACR Convergence 2020
Vitamin D Serum Status in a Cohort of COVID-19 Patients
Alberto Sulli¹, Emanuele Gotelli¹, Sabrina Paolino¹, Andrea Casabella¹, Carmen Pizzorni¹, Elisa Alessandri¹, Vanessa Smith² and Maurizio Cutolo¹, ¹Research Laboratory and Academic Division of Clinical Rheumatology, Department of Internal Medicine, University of Genova, IRCCS San Martino Polyclinic, Genoa, Italy, ²Department of Rheumatology, Ghent University Hospital, Department of Internal Medicine, VIB Inflammation Research Centre Ghent University, Ghent, Belgium
Background/Purpose: Vitamin D serum levels have been inversely associated with risk of pulmonary infections and autoimmune inflammatory disease activity and severity [1,2]. A possible role…
Abstract Number: 1129 • ACR Convergence 2020
Discordance in Patient and Physician Assessment of Disease Activity in Relapsing Polychondritis
Emily Rose¹, Marcela Ferrada¹, Kaitlin Quinn², Wendy Goodspeed¹, Laurent Arnaud³ and Peter C. Grayson⁴, ¹Systemic Autoimmunity Branch, Vasculitis Translational Research Program, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, ²Systemic Autoimmunity Branch, National Institutes of Health, NIAMS, Washington, DC, ³Department of rheumatology, University Hospitals of Strasbourg and French National Reference Center for Rare Auto-immune diseases, Strasbourg, Alsace, France, ⁴Systemic Autoimmunity Branch, National Institutes of Health, NIAMS, Bethesda, MD
Background/Purpose: Relapsing polychondritis (RP) is a rare chronic disabling inflammatory condition primarily affecting cartilage tissue. Self-reported patient outcome measures, which have not been evaluated in…
Abstract Number: 1653 • ACR Convergence 2020
Bilateral vs Unilateral Total Knee Arthroplasty: Racial Variation in Utilization and In-Hospital Major Complication Rates
Bella Mehta¹, Kaylee Ho², Jennifer Bido³, Stavros Memtsoudis³, Michael Parks⁴, Susan Goodman¹, Linda Russell⁵ and Said Ibrahim⁶, ¹Hospital for Special Surgery, Weill Cornell Medicine, New York, NY, ²Weill Cornell Medicine, New York, ³Hospital for Special Surgery, New York, ⁴Hospital for Special Surgery, Weill Cornell Medicine, New York, ⁵Hospital for Special Surgery/Weill Cornell Medicine, New York, NY, ⁶Weill Cornell Medicine, Cleveland, OH
Background/Purpose: Compared to White Patients, African Americans (AAs) are reported to have lower utilization and higher complication rates outcomes in Unilateral Total knee arthroplasty (UTKA).…
Abstract Number: 1889 • ACR Convergence 2020
Reliability and Validity of the PROMIS-29 Health Profile in Ankylosing Spondylitis Patients
Yvette Farran¹, Alexis Ogdie², John Reveille³ and Mark Hwang⁴, ¹McGovern Medical School at the University of Texas Health Sciences Center, Houston, TX, ²University of Pennsylvania, Philadelphia, PA, ³Department of Internal Medicine, University of Texas, Houston, TX, ⁴McGovern Medical School at the University of Texas Health Science Center at Houston, Houston, TX
Background/Purpose: The Patient Reported Outcomes Measurement Information System 29-Item Profile Measure (PROMIS-29) is a generic measure of health-related quality of life (HRQOL) that has seven…
Abstract Number: 0140 • ACR Convergence 2020
Meaningful Within-Patient Change in WOMAC Domains in Patients with Moderate-To- Severe Osteoarthritis
Philip G Conaghan¹, Robert Dworkin², Thomas Schnitzer³, Francis Berenbaum⁴, Andrew Bushmakin⁵, Joseph Cappelleri⁵, Lars Viktrup⁶ and Lucy Abraham⁷, ¹Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and National Institute for Health Research Leeds Biomedical Research Centre, Leeds, United Kingdom, ²University of Rochester School of Medicine and Dentistry, Rochester, NY, ³Northwestern University Feinberg School of Medicine, Chicago, IL, ⁴Sorbonne Universite�, Paris, France, ⁵Pfizer Inc, Groton, CT, ⁶Eli Lilly and Company, Indianapolis, IN, ⁷Pfizer Inc, Tadworth, United Kingdom
Background/Purpose: The Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) is a disease-specific measure of osteoarthritis (OA) symptoms (pain and stiffness) and functional impairment regularly…
Abstract Number: 0322 • ACR Convergence 2020
Development and Preliminary Validation of Smartphone Sensor-based Measurement Tools for Psoriatic Arthritis
Dan Webster¹, Rebecca Haberman², Lourdes Perez-Chada³, Stockard Simon⁴, Woody MacDuffie⁴, Michael DePhillips⁵, Soumya Reddy⁶, Alexis Ogdie⁷, Lara Mangravite⁴, Joseph Merola⁸ and Jose Scher², ¹Sage Bionetworks, Seattle, WA, ²NYU School of Medicine, New York City, ³Brigham and Women's Hospital, Harvard Medical School, Boston, MA, ⁴Sage Bionetworks, Seattle, ⁵SDP Digital, Seattle, ⁶NYU School of Medicine, New York, NY, ⁷University of Pennsylvania, Philadelphia, PA, ⁸Brigham and Women's Hospital, Harvard Medical School, Newton, MA
Background/Purpose: The COVID-19 pandemic has increasingly driven clinical care into remote settings, where patients with immune-mediated and inflammatory diseases struggle to convey symptom severity to…
Abstract Number: 0673 • ACR Convergence 2020
Gout Is an Independent Risk Factor for Undergoing an Amputation Procedure
Brian LaMoreaux¹, Megan Francis-Sedlak¹, Scott Neville² and Robert Holt¹, ¹Horizon Therapeutics plc, Lake Forest, IL, ²Foot and Ankle Center, Mooresville, IN
Background/Purpose: Gout can cause uric acid deposition in joints, soft tissues, and organs (1) and is associated with heart disease, kidney disease, hypertension, hyperlipidemia, diabetes,…
Abstract Number: 1138 • ACR Convergence 2020
Estimation of Clinically Important Differences in Patient-Reported Outcomes Measurement Information System (PROMIS) Measures in Juvenile Myositis
Madison Wolfe¹, Amanda Robinson², Jin-Shei Lai³, Theresa Coles⁴, Elizabeth Gray³, Rowland Chang³, David Cella³ and Kaveh Ardalan⁵, ¹Creighton University School of Medicine, Omaha, NE, ²Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, ³Northwestern University Feinberg School of Medicine, Chicago, IL, ⁴Duke University, Durham, ⁵Duke University Medical Center, Durham, NC
Background/Purpose: Juvenile myositis (JM) causes weakness, rashes, pain, and fatigue, thereby impacting health-related quality of life (HRQoL). Patient-Reported Outcomes Measurement Information System (PROMIS®) measures have…

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