Abstracts tagged "osteoporosis"

Abstract Number: 2532 • ACR Convergence 2023
Prevalence and Disease-Specific Factors Associated with Osteoporosis in Systemic Sclerosis: A Cross-Sectional Analysis of Two Large European Cohorts
Charles MIDOL¹, Edgar Wiebe², Elise Siegert³, Dörte Huscher⁴, Helene Behal⁵, David Launay⁶, Eric Hachulla⁷, Eric Matteson⁸, Vincent Sobanski⁹ and Frank Buttgereit², ¹Lille University Hospital, Besançon, France, ²Charité Universitätsmedizin, Dept. Rheumatology, Berlin, Germany, ³Department of Rheumatology, Charité University Hospital, Charité Platz 1, D-10117, Berlin, Germany, ⁴Institute of Biometry and Clinical Epidemiology and Berlin Institute of Health, Charité Universitätsmedizin Berlin, Berlin, Germany, ⁵Univ. Lille, CHU Lille, Biostatistics Department, Lille, France, ⁶Univ. Lille, Inserm, CHU Lille, Service de Médecine Interne, Lille, France, ⁷CHU Lille, Département de Médecine Interne et Immunologie Clinique, Centre de Référence des Maladies Auto-immunes Systémiques Rares du Nord et Nord-Ouest de France (CeRAINO), Lille, France, ⁸Mayo Clinic College of Medicine and Science, Rochester, MN, USA, Rochester, MN, ⁹Univ. Lille, Inserm, CHU Lille, U1286 - INFINITE - Institute for Translational Research in Inflammation, Lille, France
Background/Purpose: Patients with systemic sclerosis (SSc) are at increased risk for osteoporosis (OP) and associated fragility fractures. However, the risks factors and mechanisms driving bone…
Abstract Number: 1867 • ACR Convergence 2023
Peripheral Volumetric Bone Mineral Density and Erosive Disease in Patients with Established Rheumatoid Arthritis: A Cross-Sectional Study Using High-Resolution Peripheral Quantitative Computed Tomography
Mathias Hänel¹, Rasmus Klose-Jensen², Josephine Therkildsen³, Anne-Birgitte Garm Blavnsfeldt³, Bente Langdahl³, Stinus Gadegaard Hansen⁴, Kresten Keller⁵ and Ellen Margrethe Hauge³, ¹Rheumatollogy, Aarhus University Hospital, Aarhus, Denmark, ²Rheumatology, Aarhus University Hospital, Aarhus, Denmark, ³Aarhus University Hospital, Aarhus, Denmark, ⁴Odense University Hospital, Svendborg Sygehus, Svendborg, Denmark, ⁵Department of Rheumatology, Aarhus University Hospital; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark
Background/Purpose: High resolution peripheral quantitative computed tomography (HR-pQCT) is a promising imaging modality for assessing volumetric bone mineral density (BMD) in rheumatoid arthritis (RA), and…
Abstract Number: 2012 • ACR Convergence 2023
Incidence of Hyperparathyroidism in Patients with Osteoporosis Treated with Zoledronic Acid or Denosumab
Carmen Riesco Barcena¹, Jose Ivorra Cortes², Elena Grau Garcia², Samuel Leal Rodriguez², Luis Gonzalez Puig², Anderson Victor Huaylla Quispe², Pablo Francisco Muñoz Martínez³, Alba Maria Torrat Noves², Daniel Ramos Castro², Laura Mas Sanchez⁴, Ines Canovas Olmos², Hikmat Charia², Isabel Martinez Cordellat², Carmen Najera Herranz², Rosa Negueroles Albuixech², Jose Eloy Oller Rodriguez², Marta De la Rubia Navarro⁴, Ernesto Tovar Sugrañes², Elvira Vicens Bernabeu², Iago Alcantara Alvarez², Belen Villanueva Mañez² and Jose Andres Roman Ivorra⁵, ¹Hospital Universitario y Politécnico La Fe, Valencia, Spain, ²Rheumatology Department. HUP La Fe, Valencia, Spain, ³Rheumatology Department. HUP La Fe, Sagunto, Spain, ⁴Rheumatology Department. HUP La Fe, Valéncia, Spain, ⁵Hospital Universitari i Politècnic la Fe, Valencia, Spain
Background/Purpose: Denosumab and Zoledronic acid are antiresorptive drugs commonly used in the treatment of osteoporosis (OP). Zoledronic acid is a third-generation bisphosphonate that inhibits osteoclastic…
Abstract Number: 1996 • ACR Convergence 2023
Variation in Dual-energy X-ray Absorptiometry Reporting: A National Survey of Veterans Health Administration Clinics
Karla Miller¹, Melissa Steffen², Kimberly McCoy², Michelle Mengeling², Heather Davila², Shylo Wardyn² and Samantha Solimeo², ¹University of Utah School of Medicine, Salt Lake City, UT, ²Department of Veterans Affairs, Iowa City VA HCS, Iowa City, IA
Background/Purpose: Dual-energy x-ray absorptiometry (DXA) is an important tool to identify Veterans with osteoporosis, assess fracture risk, and monitor treatment response. Variability in DXA acquisition,…
Abstract Number: 2013 • ACR Convergence 2023
Clinical Characteristics and Risk Factors Associated with Fragility Fractures in Patients with Primary and Idiopathic Mast Cell Activation Syndromes
Ana Isabel Ramos Lisbona¹, Karen Carpio Astudillo¹, Filip Skrabski¹, Alicia Prieto García¹, Isabel Castrejon¹, Javier Rivera², José María Álvaro-Gracia¹ and Teresa González¹, ¹Hospital General Universitario Gregorio Marañón, Madrid, Spain, ²Hospital General Universitario Gregorio Marañon, Madrid, Spain
Background/Purpose: Mast Cell Activation Syndromes (MCAS) are a group of disorders presenting with episodic multisystem symptoms, predominantly anaphylaxis, as the result of mast cell mediator…
Abstract Number: 1998 • ACR Convergence 2023
How to Tailor Osteoporosis Therapies in Patients with Advanced Liver Disease? Variations of Renal Function by Creatinine and Cystatin C
Cristina Rodríguez-Alvear¹, Mª Carmen López-González², Elisabet Perea-Martínez³, Antonio Avilés-Hernández³, Eduardo Garín Cascales³, Nuria Buendía Sánchez³, Irene Calabuig-Sais¹, Pilar Bernabeu-Gonzálvez³, Agustín Martínez-Sanchís¹, Joaquim Esteve-Vives³, PALOMA VELA⁴, Cayetano Miralles Maciá³, Vega Jovani⁵ and Mariano Andrés¹, ¹Dr Balmis Alicante General University Hospital-ISABIAL, Alicante, Spain, ²General University Hospital Dr. Balmis, Alacante, Spain, ³General University Hospital Dr. Balmis, Alicante, Spain, ⁴Rheumatology, Hospital General Universitario Alicante, Alicante, Spain, ⁵Department of Rheumatology, Hospital General Universitario Dr. Balmis, Alicante, Spain
Background/Purpose: Rapid bone loss and increased fractures have been described after liver transplantation. Bisphosphonates are restricted in patients with significant kidney disease, as the drugs…
Abstract Number: 2014 • ACR Convergence 2023
The Role of Orosomucoid 2 in the Regulation of Bone Remodeling by Inhibiting Osteoclastogenesis and Promoting Osteogenesis
CHONG HYUK CHUNG¹, Myeung-Su Lee¹ and Chang-hoon Lee², ¹Wonkwang University Hospital, Iksan, South Korea, ²Wonkwang University Hospital, Iksan Jeonbuk, South Korea
Background/Purpose: Orosomucoid (ORM) is one of the acute phase reactant protein family and is expressed in hepatocytes and secreted into plasma under stress conditions such…
Abstract Number: 1999 • ACR Convergence 2023
One-year Incidence of Clinical Fragility Fractures After Implementing an Osteoporosis Care Protocol in Patients Eligible for Liver Transplantation
Cristina Rodríguez-Alvear¹, Mª Carmen López-González², Elisabet Perea-Martínez³, Antonio Avilés-Hernández³, Irene Calabuig-Sais¹, Maria-Luisa Peral-Garrido⁴, Pilar Bernabeu-Gonzálvez³, Agustín Martínez-Sanchís¹, Joaquim Esteve-Vives³, PALOMA VELA⁵, Cayetano Miralles Maciá³, Vega Jovani⁶ and Mariano Andrés¹, ¹Dr Balmis Alicante General University Hospital-ISABIAL, Alicante, Spain, ²General University Hospital Dr. Balmis, Alacante, Spain, ³General University Hospital Dr. Balmis, Alicante, Spain, ⁴Vinalopó University Hospital, Novelda, Spain, ⁵Rheumatology, Hospital General Universitario Alicante, Alicante, Spain, ⁶Department of Rheumatology, Hospital General Universitario Dr. Balmis, Alicante, Spain
Background/Purpose: In solid organ transplantation, liver transplants are among those most frequently associated with the development of low bone mass, which occurs in up to…
Abstract Number: 2016 • ACR Convergence 2023
Generation of a Human 3D in Vitro Bone Model That Mimics Glucocorticoid-induced Osteoporosis
Moritz Pfeiffenberger¹, Johannes Plank¹, Alexandra Damerau¹, Timo Gaber¹ and Frank Buttgereit², ¹Charité Universitatsmedizine - Berlin, Berlin, Germany, ²Charité Universitätsmedizin, Dept. Rheumatology, Berlin, Germany
Background/Purpose: Osteoporosis is a bone disease characterized by low bone mass and changes in bone architecture, leading to pain and reduced mobility in patients. Glucocorticoid-induced…
Abstract Number: 2000 • ACR Convergence 2023
Efficacy of Romosozumab for Glucocorticoid-induced Osteoporosis in Patients with Rheumatic Diseases; A Prospective Study
Mai Kawazoe¹, Kaichi Kaneko², Shotaro Masuoka³, Soichi yamada³, Zento Yamada³, Sei Muraoka³, Karin Furukawa¹, Hiroshi Sato³, Eri Watanabe³, Keiko Koshiba³, Izumi Irita³, Miwa Kanaji³ and Toshihiro Nanki¹, ¹Division of Rheumatology, Department of Internal Medicine, Toho University School of Medicine, Ota-ku, Japan, ²Division of Rheumatology, Department of Internal Medicine, Toho University Sakura Medical Center, Sakura, Japan, ³Division of Rheumatology, Department of Internal Medicine, Toho University School of Medicine, Tokyo, Japan
Background/Purpose: Glucocorticoids are widely used to treat a variety of diseases, including rheumatic diseases. Although glucocorticoids improve the outcome for these diseases, various side effects…
Abstract Number: 2017 • ACR Convergence 2023
Lupus Nephritis Is Strongly Associated with Low Bone Mineral Density and Osteoporosis in Patients with Systemic Lupus Erythematosus
Edgar Wiebe¹, Elisa Schilling², Dörte Huscher³, Andriko Palmowski⁴, Zhivana Boyadzhieva⁵, Sandra Hermann¹, Burkhard Muche¹, Tobias Alexander⁶, Falk Hiepe⁵ and Frank Buttgereit¹, ¹Charité Universitätsmedizin, Dept. Rheumatology, Berlin, Germany, ²Charité Universitätsmedizin Berlin, Dept. Rheumatology, Berlin, Germany, ³Institute of Biometry and Clinical Epidemiology and Berlin Institute of Health, Charité Universitätsmedizin Berlin, Berlin, Germany, ⁴Charité - Universitätsmedizin Berlin, Berlin, Germany, ⁵Charité Universitatsmedizine - Berlin, Berlin, Germany, ⁶Charité Universiätsmedizin Berlin, Dept. Rheumatology, Berlin, Germany
Background/Purpose: Patients with systemic lupus erythematosus (SLE) are at increased risk for osteoporosis and fragility fractures. This risk is mediated by a variety of factors…
Abstract Number: 2001 • ACR Convergence 2023
Burden of Metabolic Bone Disease in Patients with IgG4-Related Disease with and Without Autoimmune Pancreatitis
Guy Katz¹, Aubree McMahon¹, Grace McMahon¹, Isha Jha¹, Marcy Bolster², Ana Fernandes¹, Zachary Wallace³, Cory Perugino¹, John Stone⁴ and Yasmin Hernandez-Barco¹, ¹Massachusetts General Hospital, Boston, MA, ²Massachusetts General Hospital, Concord, MA, ³Massachusetts General Hospital, Newton, MA, ⁴Massachusetts General Hospital Rheumatology Unit, Harvard Medical School, Concord, MA
Background/Purpose: Metabolic bone disease (MBD), including osteopenia and osteoporosis, is common in patients with inflammatory disorders, due to disease factors and glucocorticoid (GC) use, and…
Abstract Number: 2018 • ACR Convergence 2023
Development of an Osteoporosis Treatment Gap Dashboard
Rulan Lyu¹, Patrick O'Brien¹, Tracey Wilkie¹, Yun Chang¹ and Jonathan Cheah², ¹UMass Memorial Health, Worcester, MA, ²UMass Chan Medical School, Shrewsbury, MA
Background/Purpose: Osteoporosis and the clinical event of fragility fracture is an ever-increasing public health burden. A significant osteoporosis treatment gap remains, whereby individuals with a…
Abstract Number: 2002 • ACR Convergence 2023
Cost-Effectiveness Analysis of Sequential Treatment with Abaloparatide Followed by Alendronate in US Women and Men with Multiple Previous Fractures
Mickael Hiligsmann¹, Stuart Silverman², Andrea J Singer³, Yamei Wang⁴, Leny Pearman⁴, John Caminis⁴ and Jean-Yves Reginster⁵, ¹Maastricht University, Maastricht, Netherlands, ²Cedars-Sinai Medical Center and UCLA School of Medicine, Los Angeles, CA, ³MedStar Georgetown University Hospital, Washington, DC, ⁴Radius Health, Inc., Boston, MA, ⁵University of Liège, Liège, Belgium
Background/Purpose: Patients with multiple previous fractures are at very high risk of subsequent fractures. Common treatment strategies for these patients include generic alendronate (ALN) monotherapy…
Abstract Number: 2025 • ACR Convergence 2023
Osteoporosis Treatment Attributes and Levels for an Online Decision-Making Tool for Patients: Findings from Adaptive Choice-Based Conjoint Analysis
Jeffrey Curtis¹, Kelly Gavigan², W. Benjamin Nowell³, David Curtis⁴, Danielle Ali⁵, Xiaoyu Liu⁶, Katherine Makaroff⁶, Christopher Almario⁶, Carine Khalil⁶, So Yung Choi⁷ and Brennan Spiegel⁶, ¹University of Alabama at Birmingham, Birmingham, AL, ²Global Healthy Living Foundation, Upper Nyack, NY, ³Global Healthy Living Foundation, Nyack, NY, ⁴Global Healthy Living Foundation, San Francisco, CA, ⁵Global Healthy Living Foundation, Upper Nayack, NY, ⁶Cedars-Sinai Center for Outcomes Research and Education (CS-CORE), Los Angeles, CA, ⁷Biostatistics and Bioinformatics Research Center, Cedars-Sinai Cancer, Los Angeles, CA
Background/Purpose: Osteoporosis (OP) treatment options have different attributes based on mode of administration, frequency of administration, risks of minor and serious side effects, and effectiveness,…

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