Abstracts tagged "Osteoarthritis"

Abstract Number: 1800 • 2014 ACR/ARHP Annual Meeting
Objectively Measured Sedentary Behavior Is a Distinct Risk Factor from Low Moderate-to-Vigorous Activity in Predicting Subsequent Frailty: Evidence from Osteoarthritis Initiative
Jing Song¹, Lee A. Lindquist¹, Rowland W. Chang¹, Pamela A. Semanik², Linda S. Ehrlich-Jones³, Jungwha Lee⁴, Min-Woong Sohn¹ and Dorothy D. Dunlop¹, ¹Northwestern University Feinberg School of Medicine, Chicago, IL, ²Rush University Medical Center, Chicago, IL, ³Rehabilitation Institute of Chicago, Chicago, IL, ⁴Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL
Background/Purpose: Physical frailty represents a state of high vulnerability for adverse health outcomes including disability and mortality. Physical activity interventions to improve health have largely…
Abstract Number: 197 • 2014 ACR/ARHP Annual Meeting
Differences in Total Hip Replacement Outcomes Based on Age
Leslie Harrold¹, David Ayers², Wenjun Li², Courtland Lewis³, Philip Noble⁴, Regis O'Keefe⁵, Jeroan Allison⁶ and Patricia D. Franklin², ¹Department of Orthopedics and Medicine, University of Massachusetts Medical School, Worcester, MA, ²Orthopedics and Physical Rehabilitation, University of Massachusetts Medical School, Worcester, MA, ³Hartford Hospital, Hartford, CT, ⁴Baylor College of Medicine, Houston, TX, ⁵University of Rochester Medical Center, Rochester, NY, ⁶Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, MA
Background/Purpose: The fastest growing segment of patients who undergo total hip replacement (THR) are younger than 130 surgeons across 22 states in the US. The…
Abstract Number: 1420 • 2014 ACR/ARHP Annual Meeting
Non-Use of Glucocorticoid and Osteoarthritis Absence As Predictors of Clinical Remission in AR
Salvador Loredo-Alanís¹, David Vega-Morales², Mario Garza-Elizondo¹, Mario Garcia-Pompermayer³, Roberto Negrete-López¹, Daniel Treviño-Montes¹ and Diana Flores-Alvarado², ¹Departamento de Medicina Interna del Hospital Universitario “Dr. José Eleuterio González”, Universidad Autónoma de Nuevo León, Servicio de Reumatología, Departamento de Medicina Interna del Hospital Universitario “Dr. José Eleuterio González”, Universidad Autónoma de Nuevo León, Monterrey, Mexico, ²Rheumatology, Hospital Universitario UANL, Monterrey, Mexico, ³Departamento de Medicina Interna del Hospital Universitario “Dr. José Eleuterio González”, Universidad Autónoma de Nuevo León, Servicio de Reumatología, Departamento de Medicina Interna del Hospital Universitario “Dr. José Eleuterio González”, Universidad Autónoma de Nuevo León, Monterey, Mexico
Background/Purpose The clinical evaluation of Rheumatoid arthritis (RA) is accomplished with compound indexes allowing better clinical decision. Clinical remission nowadays is an attainable target in…
Abstract Number: 187 • 2014 ACR/ARHP Annual Meeting
Revision Arthroplasty in Rheumatoid and Osteoarthritis: Does Methotrexate Decrease Radiographic Lucency in RA Patients?
Mike Wei¹, Douglas N. Mintz², Lisa A. Mandl³, Arielle Fein⁴, Jayme C. Burket⁵, Yuo-Yu Lee⁴, Wei-Ti Huang⁶, Vivian P. Bykerk⁴, Mark P. Figgie⁷, Edward F. DiCarlo⁸, Bruce N. Cronstein⁹ and Susan M. Goodman³, ¹Weill Cornell Medical College, New York, NY, ²Radiology, Hospital for Special Surgery, New York, NY, ³Rheumatology, Hospital for Special Surgery, New York, NY, ⁴Hospital for Special Surgery, New York, NY, ⁵Healthcare Research Institute, Hospital for Special Surgery, New York, NY, ⁶Biostatistics, Hospital for Special Surgery, New York, NY, ⁷Orthopedics, Hospital for Special Surgery, New York, NY, ⁸Pathology, Hospital for Special Surgery, New York, NY, ⁹NYU School of Medicine, Division of Rheumatology, New York, NY
Background/Purpose Rheumatoid arthritis (RA) patients have excellent total hip arthroplasty (THA) survival, and methotrexate (MTX), an anti-inflammatory disease modifying drug which may affect bone reabsorption,…
Abstract Number: 1291 • 2014 ACR/ARHP Annual Meeting
Relationships Between Inflammation, Disease Severity and Synovial Fluid Calcium Crystals Detected By Scanning Electronic Microscopy in Early Osteoarthritis
Paola Frallonardo¹, Francesca Oliviero¹, Luca Peruzzo², Leonardo Tauro³, Anna Scanu¹, Mariagrazia Lorenzin¹, Augusta Ortolan¹, Leonardo Punzi⁴ and Roberta Ramonda¹, ¹Rheumatology Unit, Department of Medicine, University of Padova, Padova, Italy, ²Institute for Geosciences and Earth Resources IGG-CNR, Padova, Italy, ³Department of Geosciences, University of Padova, Padova, Italy, ⁴Department of Medicine - DIMED, University of Padova, Padova, Italy
Background/Purpose The presence of calcium crystals (CC) in synovial fluid (SF) of osteoarthritis (OA) is a well known and frequent feature (1). However, their role…
Abstract Number: 108 • 2014 ACR/ARHP Annual Meeting
Patient Reported Outcomes Following Total Knee Arthroplasty in Rheumatoid Arthritis and Osteoarthritis
Anand Dusad¹, Sofia Pedro², Kevin Garvin³, Curtis Hartman⁴, James O'Dell⁵, Ted R. Mikuls⁵ and Kaleb Michaud⁶, ¹Rheumatology, University of Nebraska Medical Center, Omaha, NE, ²National Data Bank for Rheumatic Diseases, Wichita, KS, ³Orthopaedic Surgery, University of Nebraska Medical Center, Omaha, NE, ⁴Orthopaedic Surgery and Rehabilitation, University of Nebraska Medical Center, Omaha, NE, ⁵University of Nebraska Medical Center, Omaha, NE, ⁶University of Nebraska Medical Center and National Data Bank, Omaha, NE
Background/Purpose: Due to the progressive and debilitating nature of knee arthritis, total knee arthroplasty (TKA) is the ultimate outcome. TKA is an effective surgical intervention…
Abstract Number: 1284 • 2014 ACR/ARHP Annual Meeting
Sensitivity to Change of Patient Preference Outcome Measures for Pain in Trials of Patients with Knee Osteoarthritis
Matthew J. Parkes¹, Michael J. Callaghan¹, Terence W. O'Neill¹ and David T. Felson^1,2, ¹Arthritis Research UK Centre for Epidemiology, Institute of Inflammation and Repair, University of Manchester, Manchester, United Kingdom, ²Clinical Epidemiology Unit, Boston University School of Medicine, Boston, MA
Background/Purpose A variety of pain and function instruments are often measured in osteoarthritis (OA) clinical trials. Instruments with maximal sensitivity to change are preferred as the…
Abstract Number: 76 • 2014 ACR/ARHP Annual Meeting
Identification of Synovial Genes and Pathways Associated with Disease Progression in a Cohort of Early Symptomatic Osteoarthritis Patients Using a Transcriptomic Approach
Arjen B. Blom¹, Peter L. van Lent¹, Martijn H. van den Bosch², Hans Cats³, Frank H.J. van den Hoogen⁴, Floris P.J.G. Lafeber⁵, Wim B. van den Berg¹ and Peter M. van der Kraan¹, ¹Experimental Rheumatology, Radboud university medical center, Nijmegen, Netherlands, ²Experimental Rheumatology (272), Radboud university medical center, Nijmegen, Netherlands, ³Hengstdal 3, Sint Maartenskliniek, Ubbergen, Netherlands, ⁴Rheumatology, Rheumatology Centre Sint Maartenskliniek and Radboud university medical center, Ubbergen (Nijmegen), Netherlands, ⁵Rheumatology & Clinical Immunology, University Medical Center Utrecht, Utrecht, Netherlands
Background/Purpose: If and how the synovial activation that is observed in over 50% of osteoarthritis (OA) patients contributes to irreversible joint pathology, is not known.…
Abstract Number: 1285 • 2014 ACR/ARHP Annual Meeting
Prevalence of Risk Factors for Gastrointestinal Side Effects of Drugs for the Treatment of Pain in Rheumatic Diseases and the Provision of Gastroprotective Treatment – Results of a Large Non-Intervention Study
Gustavo Citera¹, Edgardo Smecuol², Alberto Millán³, Manuel Robles⁴ and Ruben Mantilla⁵, ¹Universidad de Buenos Aires, Buenos Aires, Argentina, ²Hospital Municipal de Gastroenterología, Buenos Aires, Argentina, ³Hospital Universitario de Caracas, Caracas, Venezuela, ⁴Centro Médico Toluca, Toluca, Mexico, ⁵Clínica de Artritis y Rehabilitación (CAYRE), Bogota, Colombia
Background/Purpose: Non-steroidal anti-inflammatory drugs (NSAIDs) are the long established first-line treatment for the management of pain associated with rheumatic diseases but carry a risk of…
Abstract Number: 68 • 2014 ACR/ARHP Annual Meeting
Physical Inactivity to Activity Associated with Less Decline in Physical Function
Abigail Gilbert¹, Jing Song², Pamela A. Semanik³, Rowland W. Chang⁴ and Dorothy D. Dunlop², ¹Rheumatology, Northwestern University, Chicago, IL, ²Northwestern University Feinberg School of Medicine, Chicago, IL, ³Northwestern University, Chicago, IL, ⁴Institute for Public Health and Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL
Background/Purpose: Regular physical activity has been demonstrated to improve quality of life for adults with chronic disease including osteoarthritis. Despite these benefits, half of adults…
Abstract Number: 2969 • 2014 ACR/ARHP Annual Meeting
Mortality after Knee Replacement Surgery for Osteoarthritis in a Population-Based Propensity-Score Matched Cohort
Devyani Misra¹, Tuhina Neogi², Na Lu³, David T. Felson³, Thomas Einhorn⁴, Hyon K. Choi⁵, Jessica Maxwell⁶ and Yuqing Zhang³, ¹Rheumatology, Boston University School of Medicine, Boston, MA, ²Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MA, ³Boston University School of Medicine, Boston, MA, ⁴Orthopedics, Boston University School of Medicine, Boston, MA, ⁵Division of Rheumatology, Allergy, and Immunology Massachusetts General Hospital, Harvard Medical School, Boston, MA, ⁶Physical Therapy & Athletic Training, Boston University, Boston, MA
Background/Purpose : Knee replacement (KR) surgery for osteoarthritis (OA) provides improvement in symptoms and function. Whether these improvements translate into survival benefit has been unclear,…
Abstract Number: 1088 • 2014 ACR/ARHP Annual Meeting
Socioeconomic Disparities in Health Outcomes Among Individuals with, or at Risk for, Osteoarthritis from the United States: Data from the Osteoarthritis Initiative
Antoine A. Baldassari¹, Todd Schwartz¹, Rebecca J. Cleveland¹, Joanne M. Jordan² and Leigh F. Callahan³, ¹Thurston Arthritis Research Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, ²University of North Carolina Dept of Epidemiology, Chapel Hill, NC, ³Thurston Arthritis Res Ctr, University of North Carolina, Chapel Hill, NC
Background/Purpose Socioeconomic disparities in health outcomes among people with osteoarthritis are well documented, with some key limitations: existing studies limit their analyses to few outcome…
Abstract Number: 32 • 2014 ACR/ARHP Annual Meeting
Regulation of Senescence and Inflammatory Mediators By N- and C-Terminal Parathyroid Hormone-Related Protein in Osteoarthritic Human Osteoblasts
Maria Isabel Guillén¹, Julia Platas¹, Sergio Portal-Nuñez², Pedro Esbrit³ and M.J. Alcaraz⁴, ¹Pharmacology, University of Valencia, Burjasot, Valencia, Spain, ²Metabolismo mineral y óseo, Fundación Jimenez Diaz, Madrid, Spain, ³Fundación Jimenez Diaz, Madrid, Spain, ⁴University of Valencia, Burjasot, Valencia, Spain
Background/Purpose In osteoarthritis (OA), there is an abnormal remodeling process in subchondral bone associated with an altered osteoblast metabolism. Inflammatory mediators participate in bone remodeling…
Abstract Number: 2132 • 2013 ACR/ARHP Annual Meeting
Short-Run Transitions In Pain States: Reflections Of Multiple Outcome Clinical Measures of Inadequate Pain Relief among Patients With Knee Osteoarthiritis
Stephanie Taylor¹, Christopher Black², Paul M. Peloso³, Philip G. Conaghan⁴, Leah Stokes², Mart A.F.J. van de Laar⁵, François Rannou⁶, Nigel K. Arden⁷ and Panagiotis Mavros², ¹Global Health Outcomes, Merck & Co., Inc., Whitehouse Station, NJ, ²Global Health Outcomes, Merck, Whitehouse Station, NJ, ³Clinical Research, Merck Sharp & Dohme Corp., Rahway, NJ, ⁴Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, ⁵Rheumatology, University of Twente & Medisch Spectrum Twente, Enschede, Netherlands, ⁶Physical Medicine and Rehabilitation Service, Paris-Descartes University, Cochin Hospital, Paris, France, ⁷NDORMS; MRC Lifecourse Epidemiology Unit, Oxford NIHR Musculoskeletal Biomedical Research Unit, University of Oxford, Oxford, United Kingdom
Background/Purpose: Despite the importance of pain management in osteoarthritis (OA), there has been limited evidence confirming the adequacy of measuring pain relief in clinical practice setting. The objective of…
Abstract Number: 982 • 2013 ACR/ARHP Annual Meeting
Preferred Strategies For Delivering Treatment Information To People With Rheumatoid Arthritis, Osteoarthritis and Osteoporosis
Maria A. Lopez-Olivo¹, Robert Volk², Maria Jibaja-Weiss³ and Maria E. Suarez-Almazor⁴, ¹General Internal Medicine, University of Texas. M.D Anderson Cancer Center, Houston, TX, ²General Internal Medicine, The University of Texas, MD Anderson Cancer Center, Houston, TX, ³Office of Outreach and Health Disparities, Baylor College of Medicine, Houston, TX, ⁴The Department of General Internal Medicine, The University of Texas, MD Anderson Cancer Center, Houston, TX
Background/Purpose: To explore the perceptions of people with rheumatoid arthritis (RA), osteoarthritis (OA), and osteoporosis (OP) regarding their preferred delivery methods for obtaining treatment information…

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