Abstracts tagged "Osteoarthritis"

Abstract Number: 534 • 2015 ACR/ARHP Annual Meeting
Antibodies to Malondialdehyde-Acetaldehyde Adducts Are Highly Expressed in Rheumatoid Arthritis Synovial Fluid
Rafid Rahman¹, Geoffrey M. Thiele², Andy Hollins³, Michael J. Duryee¹, Daniel Anderson³, Bartlett Hamilton⁴, Kaleb Michaud⁵, Lynell W. Klassen⁶ and Ted R. Mikuls³, ¹Internal Medicine Division of Rheumatology, University of Nebraska Medical Center, Omaha, NE, ²Omaha VA Medical Center and University of Nebraska Medical Center, Omaha, NE, ³University of Nebraska Medical Center, Omaha, NE, ⁴University of Nebraska Medical Center and Omaha VA Medical Center, Omaha, NE, ⁵Rheumatology & Immunology, University of Nebraska Medical Center and National Data Base for Rheumatic Diseases, Omaha, NE, ⁶Dept of Internal Medicine, Omaha VA Medical Center and University of Nebraska Medical Center, Omaha, NE
Background/Purpose: Malondialdehyde-acetaldehyde (MAA) adducts are expressed in synovial tissues in rheumatoid arthritis (RA). Post-translational MAA modifications are pro-inflammatory, promoting robust anti-MAA antibody responses that…
Abstract Number: 2407 • 2015 ACR/ARHP Annual Meeting
Comparison of Knee Osteoarthritis Treatment in the Non-Obese Versus Obese Populations Across Different Medical Specialties
Kelly Forrester¹, Farah Taufiq¹ and Jonathan Samuels^2,3, ¹NYU Langone Medical Center, New York, NY, ²Rheumatology, NYU - Hospital for Joint Diseases, New York, NY, ³Rheumatology, NYU Langone Medical Center, New York, NY
Background/Purpose: Knee osteoarthritis (KOA) in the obese population is underdiagnosed and routinely undertreated, as providers often attribute pain to excess weight without considering articular…
Abstract Number: 897 • 2015 ACR/ARHP Annual Meeting
Intra-Articular Corticosteroids Are Safe and Have No Major Effect on Structural Progression of Synovitic Knee OA: A 2-Year Randomized Controlled Trial of 3-Monthly Triamcinolone Hexacetonide
Jeffrey Driban¹, Michael P. Lavalley², Lori Lyn Price³, William F. Harvey⁴ and Timothy E. McAlindon⁴, ¹Tufts Medical Center, Boston, MA, ²Biostatistics, Boston University, Boston, MA, ³Clinical Care Research, Tufts Medical Center, Boston, MA, ⁴Rheumatology, Tufts Medical Center, Boston, MA
Background/Purpose: Synovitis is common in knees with OA, and is associated with structural progression. Intra-articular corticosteroids are widely used and could reduce knee OA cartilage…
Abstract Number: 2409 • 2015 ACR/ARHP Annual Meeting
Factors Associated with Physical Therapy Use in Osteoarthritis of the Knee: Results from a Population-Based Study
Sicong Huang¹, Eric C. Sayre² and Jolanda Cibere^1,2, ¹Department of Medicine, University of British Columbia, Vancouver, BC, Canada, ²Arthritis Research Canada, Richmond, BC, Canada
Background/Purpose: Osteoarthritis (OA) is the most common form of arthritis. Physical therapy (PT) has previously been demonstrated to benefit patients with osteoarthritis, especially with early…
Abstract Number: 928 • 2015 ACR/ARHP Annual Meeting
The Value of Early Ultrasound-Detected Osteophytes in Hand Osteoarthritis: Predicting the Future
Alexander Mathiessen¹, Barbara Slatkowsky-Christensen², Tore K. Kvien³, Ida K. Haugen⁴ and Hilde Berner Hammer², ¹Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, ²Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, ³Dept. of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, ⁴P.O. Box 23, Diakonhjemmet Hospital, Vinderen, Norway
Background/Purpose: Ultrasound is more sensitive than conventional radiographs in detecting small osteophytes in hand osteoarthritis (OA). Osteophytes can be seen prior to joint space narrowing…
Abstract Number: 2411 • 2015 ACR/ARHP Annual Meeting
Patient Preference for Using Technology to Track and Self-Manage Osteoarthritis
Laura Khurana, Ellen Durand, Sarah Gary, Tony Otero, Chris Hall and Susan Dallabrida, ERT, Boston, MA
Background/Purpose: Active and consistent self-management is essential for patients suffering from chronic diseases to improve their health. Electronic clinical (eClinical) technology may improve how patients…
Abstract Number: 951 • 2015 ACR/ARHP Annual Meeting
Comparative Effectiveness of Tai Chi Versus Physical Therapy in Treating Knee Osteoarthritis: A Randomized, Single-Blind Trial
Chenchen Wang^1,2, Christopher Schmid³, Maura D. Iversen⁴, William F. Harvey², Roger A. Fielding⁵, Jeffrey B. Driban², Lori Lyn Price⁶, John B. Wong^7,8, Kieran Reid⁵, Ramel Rones⁹ and Timothy E. McAlindon², ¹Rheumatology, Tufts Medical Center, Bosotn, MA, ²Rheumatology, Tufts Medical Center, Boston, MA, ³Brown University School of Public Health, Providence, RI, ⁴Northeastern University,, Boston, MA, ⁵Nutrition, Exercise Physiology and Sarcopenia Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA, ⁶Clinical Care Research, Tufts Medical Center, Boston, MA, ⁷Tufts Medical Center, Boston, MA, ⁸Clinical Decision Making, Tufts Medical Center, Boston, MA, ⁹Center for Mind–Body Therapies, Boston, MA
Background/Purpose: Knee osteoarthritis (OA) causes long-term pain and no effective treatments currently exist. Previous trials demonstrated that Tai Chi can improve both physical and mental…
Abstract Number: 2412 • 2015 ACR/ARHP Annual Meeting
Assessment and Comparison of Responsiveness of Four Patient Reported Outcome Measures to Assess Physical Function in Patients with Knee Osteoarthritis: WOMAC-PF Subscale Responds Best
Elien A.M. Mahler¹, Nienke Cuperus², Johannes W J Bijlsma³, Thea Vliet Vlieland⁴, Frank H.J. van den Hoogen⁵, Alfons den Broeder⁵ and Cornelia H.M. van den Ende¹, ¹Department of Rheumatology, Sint Maartenskliniek, Nijmegen, Netherlands, ²Rheumatology Department, Sint Maartenskliniek, Nijmegen, Netherlands, ³Rheumatology and Clinical Immunology, ARC Amsterdam; UMC Utrecht, Utrecht, Netherlands, ⁴Rheumatology, Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ⁵Rheumatology, Sint Maartenskliniek, Nijmegen, Netherlands
Background/Purpose: Although physical function is one of the core outcome domains in knee osteoarthritis (OA), the ability of a measurement instrument to detect changes over…
Abstract Number: 953 • 2015 ACR/ARHP Annual Meeting
Effectiveness of a Progressive Resistence Strength Programme on Hand Osteoarthritis: A Randomized Crontrolled Trial
Michele V. Nery¹, Anamaria Martinez², Fabio Jennings³, Marcelo Souza² and Jamil Natour², ¹Rheumatology Division, Universidade Federal de Sao Paulo, Sao Paulo, Brazil, ²Rheumatology Division, Federal University of Sao Paulo, Sao Paulo, Brazil, ³Disciplina de reumatologia, Universidade Federal de São Paulo, Sao Paulo, Brazil
Background/Purpose: Hand osteoarthritis (OA) is highly prevalent, affecting 55-70% of the population over 55 years with an age-related progressive increase. The OA of interphalangeal (IF)…
Abstract Number: 2617 • 2015 ACR/ARHP Annual Meeting
Serum 14-3-3eta Protein Elevation in Osteoarthritis Suggests Misclassification or Concurrent Inflammatory Arthritis
Olga S. Zhukov¹, Jonnielyn G. Rivera¹, Rania W. Abolhosn¹, Robert J. Lagier², Charles M. Rowland³, Joanna M. Popov¹, Kaleb Michaud⁴ and Stanley J. Naides¹, ¹Immunology, Quest Diagnostics Nichols Institute, San Juan Capistrano, CA, ²Research Support, Alameda, Quest Diagnostics Alameda, Alameda, CA, ³Research Support, Quest Diagnostics Alameda, Alameda, CA, ⁴Rheumatology & Immunology, University of Nebraska Medical Center and National Data Bank, Omaha, NE
Background/Purpose: Tissue distribution of the chaperonin 14-3-3η (eta) is limited to synovial tissue and brain. Synovium releases proinflammatory 14-3-3η into synovial fluid and serum in…
Abstract Number: 1150 • 2015 ACR/ARHP Annual Meeting
Novel Chitosan Hydrogels for the Treatment of Osteoarthritis: Mechanical Support, Lubrication and Prevention of Cartilage Degradation in a Rabbit Model of Osteoarthritis
Yves Henrotin^1,2, Frédéric Oprenyeszk¹, Fanny Comblain³, Jean-Emile Dubuc⁴, Christelle Boileau⁵, Mickaël Chausson⁶, Renaud Lecler⁶, Guillem Rocasalbas⁶, Pierre Douette⁶ and Sandrine Gautier⁶, ¹Bone and Cartilage Research Unit, Arthropôle Liege, University of Liege, Liege, Belgium, ²Physical Therapy and Rehabilitation Department, Princess Paola Hospital, Marche-en-Famenne, Belgium, ³University of Liège, Bone and Cartilage Research Unit, Arthropôle Liege, University of Liege, Liege, Belgium, ⁴Clinical University Saint Luc, Orthopaedic Department, Clinical University Saint Luc, Brussels, Belgium, ⁵Artialis S.A.,11 Avenue de l’Hôpital, Tour Giga+3, Liege, Belgium, ⁶Synolyne Pharma, rue Haute Claire 4, Herstal, Belgium
Background/Purpose: Chitosan, a glucosamine polysaccharide, is a good candidate for viscosupplementation in OA joints. Herein, we report the physico-chemical properties and the effects of an…
Abstract Number: 3086 • 2015 ACR/ARHP Annual Meeting
The Same Multidimensional Patient Health Assessment Questionnaire Used to Assess RAPID3 in Rheumatoid Arthritis, Osteoarthritis and Other Rheumatic Diseases Can Provide Quantitative Clues to Recognize and Document Comorbid Fibromyalgia
Kathryn A. Gibson¹, Annie Huang² and Theodore Pincus², ¹Liverpool Hospital, Liverpool, Australia, ²Rheumatology, Rush University Medical Center, Chicago, IL
Background/Purpose: An MDHAQ/RAPID3 (Multidimensional Health Assessment Questionnaire/Routine Assessment of Patient Index Data) is a 2 sided, 1 page questionnaire which is completed by patients in…
Abstract Number: 126 • 2015 ACR/ARHP Annual Meeting
Patients with Osteoarthritis and Rheumatoid Arthritis Seen at 4 Different Routine Rheumatology Care Sites at This Time Have Similar and Patient and Physician Global Estimates of Severity, and Scores for Functional Disability, Pain, and RAPID3
Carlos El-Haddad¹, Isabel Castrejón², Kathryn A. Gibson³, Yusuf Yazici⁴, Martin Bergman⁵ and Theodore Pincus², ¹Rheumatology, Liverpool Hospital, NSW, Australia, ²Rheumatology, Rush University Medical Center, Chicago, IL, ³Liverpool Hospital, Liverpool, Australia, ⁴NYU Hospital for Joint Diseases, New York, NY, ⁵Division of Rheumatology, Taylor Hospital, Ridley Park, PA
Background/Purpose: RA generally is regarded by physicians and the public as a more severe problem than OA. However, OA has been ranked as the 11th…
Abstract Number: 1258 • 2015 ACR/ARHP Annual Meeting
Identification of a Spectrum of Therapeutic Targets of a New Treatment for Osteoarthritis Composed By Curcuminoids Extract, Hydrolyzed Collagen and Green Tea Extract
Fanny Comblain¹, Cécile Lambert¹, Isabelle Lesponne², Christelle Sanchez¹, Jean-Emile Dubuc³ and Yves Henrotin^4,5, ¹University of Liège, Bone and Cartilage Research Unit, Arthropôle Liege, University of Liege, Liege, Belgium, ²Royal Canin Research Center, Aimargues, France, ³Clinical University Saint Luc, Orthopaedic Department, Clinical University Saint Luc, Brussels, Belgium, ⁴Physical Therapy and Rehabilitation Department, Princess Paola Hospital, Marche-en-Famenne, Belgium, ⁵Bone and Cartilage Research Unit, Arthropôle Liege, University of Liege, Liege, Belgium
Background/Purpose: The goal of treatment in OA is to reduce pain and improve function. There is no cure for the disease, but some attempts to…
Abstract Number: 3250 • 2015 ACR/ARHP Annual Meeting
Systemic Inflammation and Pain Sensitization in Knee Osteoarthritis: The Multicenter Osteoarthritis Study
Tuhina Neogi¹, Laura Frey-Law², Devyani Misra¹, Michael C. Nevitt³, Lars Arendt-Nielsen⁴, Emily K. Quinn⁵ and Cora E. Lewis⁶, ¹Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MA, ²UIowa, Iowa City, IA, ³Epidemiology and Biostatistics, UCSF, San Francisco, CA, ⁴Aalborg University, Aalborg, Denmark, ⁵Data Coordinating Center, Boston University School of Public Health, Boston, MA, ⁶Preventive Medicine, University of Alabama at Birmingham, Birmingham, AL
Background/Purpose: Pain sensitization is associated with pain severity in knee osteoarthritis (OA), but its cause in humans is not well-understood. We recently demonstrated that local…

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