Abstracts tagged "Osteoarthritis"

Abstract Number: 1921 • ACR Convergence 2022
Association Between Knee Osteoarthritis and Health-Related Quality of Life in Persons with Type 2 Diabetes
Lauren King¹, Esther Waugh¹, Ian Stanaitis², Alanna Weisman¹, Baiju Shah¹, Lorraine Lipscombe¹ and Gillian Hawker¹, ¹University of Toronto, Toronto, ON, Canada, ²Women's College Hospital, Toronto, ON, Canada
Background/Purpose: Knee osteoarthritis (OA) and type 2 diabetes commonly co-occur due to shared risk factors. Both knee OA and type 2 diabetes negatively impact health-related…
Abstract Number: 0017 • ACR Convergence 2022
Intra-articular Injection of Bacterial DNA Amplified from Human OA Patient Cartilage Worsens OA Outcomes in Mice
Leoni Schlupp¹, Emmaline Prinz¹, Vladislav Izda², Emily Nguyen¹, Christopher Dunn³ and Matlock Jeffries¹, ¹Oklahoma Medical Research Foundation, Oklahoma City, OK, ²Oklahoma Medical Research Foundation, New York, NY, ³University of Oklahoma Health Sciences Center, Edmond, OK
Background/Purpose: We have previous demonstrated a bacterial DNA signature within cartilage of humans and mice and shown shifts in this signature with OA development. However,…
Abstract Number: 0213 • ACR Convergence 2022
“The Best Part Is Feeling Like I Could Go out There and Maybe Really Help Somebody”: Training Peer Coaches to Deliver the Moving Well Total Knee Replacement Telephone-Based Coaching Program
Yuliana Domínguez Páez¹, Mackenzie Brown², Assem Jabri³, Megan Creasman⁴, Shanthini Kasturi⁵, Monika Safford³ and Iris Navarro-Millan³, ¹Weill Cornell Medicine, Bronx, NY, ²Weill Cornell Medicine, Brooklyn, NY, ³Weill Cornell Medicine, New York, NY, ⁴NYP-Weill Cornell, New York, NY, ⁵Tufts Medical Center, Boston, MA
Background/Purpose: Up to 30% of patients with advanced knee osteoarthritis (KOA) experience knee pain after recovering from Total Knee Replacement (TKR). Studies suggest that high…
Abstract Number: 0847 • ACR Convergence 2022
Association of Frontal Plane Trunk Motion During Gait with Abductor Strength, Fatigue, and Physical Activity in Women with Hip Osteoarthritis
Sanghamitra Nayak¹, Burcu Aydemir², Chun-Hao Huang³ and Kharma Foucher¹, ¹University of Illinois at Chicago, Chicago, IL, ²Northwestern University, Chicago, IL, ³Northeastern University, Boston, MA
Background/Purpose: We have previously reported that fatigue and hip abductor weakness are associated with reduced physical activity (PA) in women with hip osteoarthritis (OA). We…
Abstract Number: 1640 • ACR Convergence 2022
Tryptophan Metabolites Are Associated with Erosion and Symptoms in Hand Osteoarthritis: Results from the DIGICOD Cohort
Marie Binvignat¹, Patrick Emond², Brenda Miao³, Alice Courties⁴, Emmanuel Maheu⁵, Margreet Kloppenburg⁶, Pascal Richette⁷, Atul Butte³, Encarnita Mariotti-Ferrandiz¹, Francis Berenbaum⁸, Harry Sokol⁹ and Jérémie SELLAM¹⁰, ¹Sorbonne Universite, Paris, France, ²Tours University, Tours, France, ³UCSF, San Francisco, CA, ⁴Service de Rhumatologie, AP-HP Hopital Saint-Antoine, Sorbonne Universite, INSERM, Centre de Recherche Saint-Antoine, Paris, France, Paris, France, ⁵Hopital Paris Saint Antoine, Moirans, Auvergne-Rhone-Alpes, France, ⁶Leiden University Medical Center, Leiden, Netherlands, ⁷Department of Rheumatology, Hôpital Lariboisière, Assistance Publique-Hôpitaux de Paris, Paris, France, ⁸Sorbonne University - Saint-Antoine hospital, Paris, France, ⁹Sorbonne Universite Saint Antoine Hospital, Paris, France, ¹⁰Sorbonne Universite, AP-HP, Saint-Antoine hospital, Paris, France
Background/Purpose: Tryptophan (Trp) and its metabolites have been linked to inflammatory processes and associated with gut dysbiosis. However, their role in osteoarthritis (OA) is unknown.…
Abstract Number: 1890 • ACR Convergence 2022
The Efficacy of Intra-articular Triamcinolone Acetonide 10 mg vs. 40 mg in Patients with Knee Osteoarthritis: a Non-inferiority, Randomized, Controlled, Double-blind, Multicenter Study
Sumapa Chaiamnuay¹, Komchan Utamawatin², Ong-art Phruetthiphat² and Rit Apinyankul³, ¹Phramongkutklao hospital, Nonthaburi, Thailand, ²Phramongkutklao Hospital, Bangkok, Thailand, ³Konkaen University Hospital, Konkaen, Thailand
Background/Purpose: Intra-articular (IA) corticosteroid injection is recommended in refractory knee osteoarthritis patients. However, 40-mg of triamcinolone IA every 3 months for 2 years reduces cartilage…
Abstract Number: 1906 • ACR Convergence 2022
Bile Acid Profile Is Associated to Synovitis in Knee Osteoarthritis
Roxana Coras¹, Jessica Murillo Saich², Michal Hose Sanchez³, Anne Quan³, Emily Gentry¹, Pieter Dorrestein¹, Nancy Lane⁴ and Monica Guma⁵, ¹University of California San Diego, San Diego, CA, ²University of California San Diego, La Jolla, CA, ³VA San Diego Healthcare System, San Diego, CA, ⁴University of California Davis, Hillsborough, CA, ⁵Division of Rheumatology, Allergy, and Immunology, Department of Medicine, University of California San Diego, La Jolla, CA
Background/Purpose: Increasing evidence indicates that low grade systemic and local inflammation contributes to osteoarthritis (OA) progression. Bioactive lipid mediators are signaling molecules involved in inflammatory…
Abstract Number: 1922 • ACR Convergence 2022
Multi-Joint Osteoarthritis Phenotypes by Race/Ethnicity and Sex: Preliminary Descriptive Data from the Johnston County Health Study
Sherwin Novin¹, Carolina Alvarez², Todd Schwartz³, Yvonne Golightly⁴ and Amanda Nelson², ¹University of North Carolina, Chapel Hill, NC, ²University of North Carolina at Chapel Hill, Chapel Hill, NC, ³University of North Carolina-Chapel Hill, Chapel Hill, NC, ⁴University of Nebraska Medical Center, Omaha, NE
Background/Purpose: To describe phenotypes of multi-joint osteoarthritis (MJOA) definitions by race/ethnicity and sex in a community-based cohort.Methods: The Johnston County Health Study (JoCoHS) is an…
Abstract Number: 0018 • ACR Convergence 2022
Longitudinal Development of Cartilage Microbial DNA Profiles Following Oral Microbiome Inoculation
Emmaline Prinz¹, Leoni Schlupp¹, Vladislav Izda², Emily Nguyen¹, Christopher Dunn³, Cassandra Sturdy¹ and Matlock Jeffries¹, ¹Oklahoma Medical Research Foundation, Oklahoma City, OK, ²Oklahoma Medical Research Foundation, New York, NY, ³University of Oklahoma Health Sciences Center, Edmond, OK
Background/Purpose: Previous studies have associated microbiome changes with human OA and post-traumatic OA mouse models. Our group has previously published a description of cartilage microbial…
Abstract Number: 0398 • ACR Convergence 2022
Comparison of Spondyloarthritis, Rheumatoid Arthritis and Knee Osteoarthritis Occurring in the Setting of HIV Infection
Benjamin Naovarat¹, John Reveille¹, Mark Hwang², Francis Williams³ and Gloria Salazar⁴, ¹University of Texas McGovern Medical School, Houston, TX, ²McGovern Medical School at the University of Texas Health Science Center at Houston, Houston, TX, ³Specialists for Health/Wellmed, Shavano Park, TX, ⁴University of Texas Medical School at Houston/McGovern Medical School, Houston, TX
Background/Purpose: Early in the HIV epidemic, autoimmune diseases such as lupus and rheumatoid arthritis (RA) were uncommonly encountered. With the advent of combined antiretroviral therapy…
Abstract Number: 0849 • ACR Convergence 2022
The Impact of Diabetes Status on Pain and Disability Following Total Joint Arthroplasty for Hip and Knee Osteoarthritis: Variation by Sex and Body Mass Index
J Denise Power¹, Anthony Perruccio², J Roderick Davey², Rajiv Gandhi², Nizar Mahomed², Khalid Syed², Christian Veillette² and Y Raja Rampersaud², ¹Schroeder Arthritis Institute, University Health Network, Toronto, ON, Canada, ²Schroeder Arthritis Institute, University Health Network; University of Toronto, Toronto, ON, Canada
Background/Purpose: Hip and knee total joint arthroplasties (TJA) for osteoarthritis (OA) are frequently performed surgical procedures, representing the majority of direct expenditures for OA. TJA…
Abstract Number: 1641 • ACR Convergence 2022
Determination and Characterization of Patient Subgroups with Different Pain Progression in Hand Osteoarthritis
Coen van der Meulen¹, Lotte van de Stadt¹, Frits Rosendaal¹, Jos Runhaar² and Margreet Kloppenburg¹, ¹Leiden university medical center, Leiden, Netherlands, ²Erasmus Medical Center, Rotterdam, Netherlands
Background/Purpose: Pain is central to hand osteoarthritis (OA). Previous studies reported stable mean pain levels on the short to midterm. Subgroups with different pain trajectories…
Abstract Number: 1891 • ACR Convergence 2022
Osteoarthritis of the Knee, Inflammation, and the Effect of Adalimumab: A Randomized Placebo-Controlled Trial
Walter P Maksymowych¹, Louis Bessette², Robert G Lambert³, Amanda Carapellucci⁴ and Tom Appleton⁵, ¹Department of Medicine, University of Alberta, Edmonton, AB, Canada, ²Centre de l'Ostoporose et de Rhumatologie de Québec, Québec, QC, Canada, ³University of Alberta, Edmonton, AB, Canada, ⁴CARE Arthritis LTD, Edmonton, AB, Canada, ⁵The University of Western Ontario, London, ON, Canada
Background/Purpose: Recent RCTs demonstrated that TNFα inhibition has no effect on pain and MRI-detected synovitis or bone marrow lesions in patients with erosive hand OA.…
Abstract Number: 1907 • ACR Convergence 2022
Strength Training Associates with Less Knee Osteoarthritis: Data from the Osteoarthritis Initiative
Grace Lo¹, Michael Richard², Timothy McAlindon³, Andrea Kriska⁴, Bonny Rockette-Wagner⁴, Charles Eaton⁵, Marc Hochberg⁶, Rebecca Jackson⁷, Kent Kwoh⁸, Michael Nevitt⁹ and Jeffrey Driban¹⁰, ¹Baylor College of Medicine, Houston, TX, ²Tufts Medical Center, Boston, MA, ³Tufts Medical Center, Arlington, MA, ⁴University of Pittsburgh, Pittsburgh, PA, ⁵Brown University, Pawtucket, RI, ⁶University of Maryland School of Medicine, Baltimore, MD, ⁷The Ohio State University, Columbus, OH, ⁸University of Arizona, Tucson, AZ, ⁹University of California San Francisco, Orinda, CA, ¹⁰Tufts Medical Center, Westborough, MA
Background/Purpose: Engagement in strength training has become increasingly popular and is an activity that can involve weight-bearing, heavy lifting, and frequent knee bending; and thus…
Abstract Number: 1923 • ACR Convergence 2022
Co-fluctuations of Knee Pain Between Knees in the Same Person: Data from the Osteoarthritis Initiative (OAI)
Martin Englund¹, Tuhina Neogi² and Aleksandra Turkiewicz¹, ¹Lund University, Lund, Sweden, ²Boston University School of Medicine, Boston, MA
Background/Purpose: Pain in knee osteoarthritis (OA) is often known to fluctuate. However, there is limed knowledge of the pain fluctuations in between knees within the…

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