Abstracts tagged "Osteoarthritis"

Abstract Number: 0217 • ACR Convergence 2021
The OMERACT Knee Inflammation MRI Scoring System: Validation of Quantitative Methodologies and Tri-compartmental Overlays by Comparison with the MRI Osteoarthritis Knee Score
Walter Maksymowych¹, Jacob Jaremko², Susanne Pedersen³, Iris Eshed⁴, Ulrich Weber⁵, Paul Bird⁶, Andrew McReynolds², Stephanie Wichuk², Joel Paschke⁷ and Robert Lambert², ¹Department of Medicine, University of Alberta, Alberta, Canada, Edmonton, AB, Canada, ²University of Alberta, Edmonton, AB, Canada, ³Rigshospitalet, Center for Arthritis Research, Glostrup, Denmark, ⁴Sheba Medical Center, Ramat Gan, Israel, ⁵Practice Buchsbaum Schaffhausen, Schaffhausen, Switzerland, ⁶University of New South Wales, Sydney, Australia, ⁷CARE Arthritis, Edmonton, AB, Canada
Background/Purpose: Bone marrow lesions (BML) and synovitis on MRI are independently associated with the severity and progression of osteoarthritis (OA) and randomized controlled trials have…
Abstract Number: 0583 • ACR Convergence 2021
Obesity and Lower Socioeconomic Position Are Independently Associated with Incident Osteoarthritis and Rheumatoid Arthritis: Results from the English Longitudinal Study of Ageing
Rozemarijn Witkam¹, James Gwinnutt¹, Jennifer Humphreys¹, Rachel Cooper², David Selby¹ and Suzanne Verstappen³, ¹University of Manchester, Manchester, United Kingdom, ²Manchester Metropolitan University, Manchester, United Kingdom, ³School of Social Sciences, The University of Manchester, Manchester, United Kingdom
Background/Purpose: Obesity is a known risk factor for OA and hypothesised as a risk factor for RA, although due to different underlying mechanisms. Lower socioeconomic…
Abstract Number: 0848 • ACR Convergence 2021
Automatic Hand Segmentation from Hand X-rays Using Minimized Training Samples and Machine Learning Models
Zilong Yang¹, Juan Shan², Carmine Guida², Jordan Blackadar¹, Tino Cheung¹, Jeffrey Driban³, Timothy McAlindon⁴ and Ming Zhang¹, ¹Wentworth Institute of Technology, Boston, MA, ²Pace University, New York, NY, ³Tufts Medical Center, Boston, MA, ⁴Tufts Medical Center, Arlington, MA
Background/Purpose: In many hand osteoarthritis (OA) studies (e.g., automatic Joint Space Width measuring), accurate hand segmentation is the first step towards making further analysis. However,…
Abstract Number: 1118 • ACR Convergence 2021
The Association of Hand OA with Paid an Unpaid Work Impairment and Related Costs: The Hand Osteoarthritis in Secondary Care Cohort
Sietse Terpstra¹, Lotte van de Stadt¹, Annelies Boonen², Frits Rosendaal¹ and Margreet Kloppenburg¹, ¹Leiden University Medical Center, Leiden, Netherlands, ²Department of Internal Medicine, Division of Rheumatology, Maastricht University Medical Centre+ (MUMC+), Maastricht, Limburg, Netherlands
Background/Purpose: Rheumatic musculoskeletal diseases (RMDs) can cause impairment at paid and unpaid work and contributes to societal burden and costs. However, data on this topic…
Abstract Number: 1134 • ACR Convergence 2021
Osteoarthritis Risk Is Increased in Patients with Atopic Disease
Matthew Baker¹, Khushboo Sheth², Rong Lu³, Di Lu³, Ericka von Kaeppler⁴, Archana Bhat⁴, David Felson⁵ and William Robinson⁴, ¹Stanford University, Menlo Park, CA, ²Stanford University/VA Palo Alto, Atherton, CA, ³Stanford University, Stanford, ⁴Stanford University, Palo Alto, CA, ⁵Boston University, Boston, MA
Background/Purpose: Osteoarthritis (OA) is a highly prevalent disease resulting in joint pain and impaired function. Allergic pathways, including mast cell activation, may play a key…
Abstract Number: 1588 • ACR Convergence 2021
Relation of Foot and Ankle Pain to Worsening Knee Pain: The MOST Study
Patrick Corrigan¹, David Felson², Tuhina Neogi³, Cara Lewis⁴, James Torner⁵, Michael Nevitt⁶, Cora Lewis⁷ and Joshua Stefanik¹, ¹Northeastern University, Boston, MA, ²Boston University, Boston, MA, ³Boston University School of Medicine, Boston, MA, ⁴Boston University, Brookline, MA, ⁵University of Iowa, Iowa City, IA, ⁶University of California San Francisco, Orinda, CA, ⁷University of Alabama Birmingham, Birmingham, AL
Background/Purpose: Foot and ankle pain may be a risk factor for worsening knee pain in those with or at risk for knee osteoarthritis (KOA). Foot…
Abstract Number: 0218 • ACR Convergence 2021
Synovitis Does Not Mediate the Relationship Between Body Mass Index and Progression of Radiographic Knee Osteoarthritis: Data from the Osteoarthritis Initiative
Marina Bañuls¹, Alecio Lombardi¹, Eric Chang¹, Aladdin H Shadyab¹, Nancy Lane² and Monica Guma³, ¹University of California San Diego, San Diego, CA, ²University of California Davis, Hillsborough, CA, ³University of California San Diego, La Jolla, CA
Background/Purpose: Synovial inflammation is associated with knee osteoarthritis (KOA) progression. Body mass index (BMI) has also been associated with KOA progression. Yet, it is unclear…
Abstract Number: 0593 • ACR Convergence 2021
Labour Force Participation Among Individuals with Osteoarthritis, Rheumatoid Arthritis/Other Arthritis Types, or with Joint Symptoms but Without a Diagnosis: An Age-Stratified Population-Based Study
Shatabdy Zahid, Elizabeth Badley and Anthony Perruccio, Schroeder Arthritis Institute, University Health Network, Toronto, ON, Canada
Background/Purpose: Having arthritis is known to affect labour force participation. Most research has focused on individuals with doctor-diagnosed rheumatoid arthritis (RA) and, to a lesser…
Abstract Number: 0850 • ACR Convergence 2021
Regression Methods for Modeling Western Ontario and McMaster Universities Arthritis Index (WOMAC) Pain Scores for Early Stage Knee Osteoarthritis
Benjamin Sweigart and Michael LaValley, Boston University School of Public Health, Boston, MA
Background/Purpose: The Western Ontario and McMaster Universities Arthritis Index (WOMAC) pain score [range 0-20] is a common outcome measure for clinical trials and observational studies…
Abstract Number: 1119 • ACR Convergence 2021
Systematic Review of Non-surgical Therapies for Hand Osteoarthritis
Haonan Mi, Christopher Oh and Tanveer Towheed, Queen's University, Kingston, ON, Canada
Background/Purpose: This systematic review evaluated all published randomized controlled trials (RCTs) assessing pharmacological and non-pharmacological therapies in patients with hand osteoarthritis (HOA).Methods: The following electronic…
Abstract Number: 1168 • ACR Convergence 2021
Barriers to Effectiveness of Non-surgical Treatments for Knee Osteoarthritis in a Diverse Racial/Ethnic Population: A Nominal Group Qualitative Study
Jasvinder Singh, University of Alabama at Birmingham, Birmingham, AL
Background/Purpose: Knee osteoarthritis (OA) has worse outcome in racial/ethnic minorities, who also have more severe pain, disability and worse outcomes. However, most qualitative studies include…
Abstract Number: 1671 • ACR Convergence 2021
COVID-19 in Patients with Rheumatoid Arthritis Compared to Patients with Osteoarthritis During the Pandemic in New York City
Jonah Levine¹, Vivian Bykerk², Lindsay Lally¹, Lisa Mandl¹ and Medha Barbhaiya¹, ¹Hospital for Special Surgery, New York, NY, ²Division of Rheumatology, Hospital for Special Surgery, New York City, NY
Background/Purpose: COVID-19 in patients with rheumatoid arthritis (RA) is poorly understood. A recent study of mostly men with RA demonstrated increased COVID-19 risk in RA…
Abstract Number: 0219 • ACR Convergence 2021
Intra-Articular Mineralization on Knee CT and Risk of Cartilage Loss: The Multicenter Osteoarthritis Study
Jean Liew¹, John Lynch², Ali Guermazi¹, Mohamed Jarraya³, David Felson¹, Na Wang¹, Cora Lewis⁴, James Torner⁵, Michael Nevitt⁶ and Tuhina Neogi⁷, ¹Boston University, Boston, MA, ²University of California San Francisco, San Francisco, CA, ³Massachusetts General Hospital, Boston, MA, ⁴University of Alabama Birmingham, Birmingham, AL, ⁵University of Iowa, Iowa City, IA, ⁶University of California San Francisco, Orinda, CA, ⁷Boston University School of Medicine, Boston, MA
Background/Purpose: Intra-articular (IA) mineralization due to crystal deposition may contribute to OA pathology through inflammation, release of pro-catabolic factors, or altered cartilage biomechanical properties. Prior…
Abstract Number: 0723 • ACR Convergence 2021
Size of Regression to the Mean in First-Line Interventions for Osteoarthritis: An Illusion of Effectiveness
Martin Englund and Aleksandra Turkiewicz, Lund University, Lund, Sweden
Background/Purpose: Persons who seek treatment for osteoarthritis (OA) are likely doing so when experiencing a flare-up in pain. Due to natural fluctuation of pain, this…
Abstract Number: 0851 • ACR Convergence 2021
Application of a Modified Recursive Feature Elimination Machine Learning Algorithm to Select Predictors of Mortality in Those with and Without Osteoarthritis
Siyeon Kim¹, Siqi Xiang¹, Liubov Arbeeva¹, Carolina Alvarez¹, Amanda Nelson¹, Yvonne Golightly¹, Leigh Callahan², Michael Kosorok¹ and Becki Cleveland³, ¹University of North Carolina at Chapel Hill, Chapel Hill, NC, ²University of North Carolina Thurston Arthritis Research Center, Chapel Hill, NC, ³Thurston Arthritis Research Center, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC
Background/Purpose: Radiographic osteoarthritis (rOA) and joint symptoms at the knee and hip are predictors of mortality. However, questions remain about the nature of the relationship…

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