Abstracts tagged "Osteoarthritis"

Abstract Number: 1057 • ACR Convergence 2021
Impact of Osteoarthritis in Younger Adults
Elizabeth Badley¹, Jessica Wilfong² and Anthony Perruccio¹, ¹Schroeder Arthritis Institute, University Health Network, Toronto, ON, Canada, ²Shcroeder Arthritis Institute, University Health Network, Toronto, ON, Canada
Background/Purpose: OA is a disease frequently perceived as a disease of the elderly and an inevitable result of aging. Consequently, epidemiological and clinical studies of…
Abstract Number: 1130 • ACR Convergence 2021
Osteoarthritis Patients Feel Their Tissue Remodeling
Anne-Christine Bay-Jensen¹, Yi He², Christian Thudium¹ and Morten Karsdal³, ¹Nordic Bioscience, Herlev, Denmark, ²Nordic Bioscience A/S, Herlev, Denmark, ³Nordic Bioscience, Herlev
Background/Purpose: Osteoarthritis (OA) is a chronic disease characterized by pain and disability. Central to the revised FDA guidelines for the approval of a disease modifying…
Abstract Number: 1478 • ACR Convergence 2021
An Orphan Receptor and Osteoarthritis: Mouse Gpr34 Expression in Dorsal Root Ganglia After Partial Meniscectomy
David Thomas¹, Terese Geraghty², Alia Obeidat², Jun Li², Rachel Miller² and Anne-Marie Malfait³, ¹University of Minnesota Internal Medicine Residency, St. Paul, MN, ²Rush University Medical Center, Chicago, IL, ³Rush University, Chicago, IL
Background/Purpose: Osteoarthritis (OA) is one of the leading causes of musculoskeletal pain and disability. Worldwide, an estimated 303 million patients have clinically diagnosed OA, with…
Abstract Number: 0214 • ACR Convergence 2021
Baseline Cam or Pincer Morphology Is Associated with Loss of Quantitative Joint Space Width at the Hip: The Johnston County Osteoarthritis Project
Amanda Nelson¹, Carolina Alvarez¹, Yvonne Golightly¹, Jamie Stiller², Jordan Renner¹, Nigel Arden³, Charles Ratzlaff⁴ and Jeffrey Duryea⁵, ¹University of North Carolina at Chapel Hill, Chapel Hill, NC, ²Alamance Regional Medical Center, Durham, NC, ³University of Oxford, Oxford, United Kingdom, ⁴University of British Columbia, Vancouver, BC, Canada, ⁵Brigham and Women's Hospital, Boston, MA
Background/Purpose: To determine the association between radiographic cam and pincer morphology and loss of hip quantitative joint space width (qJSW) in a community-based cohort.Methods: Data…
Abstract Number: 0483 • ACR Convergence 2021
Frequent Use of Prescription Oral NSAIDs Among People with Knee or Hip Osteoarthritis Despite Contraindications to or Precautions with NSAIDs
Tuhina Neogi¹, Andrea Dell'isola², Martin Englund² and Aleksandra Turkiewicz², ¹Boston University School of Medicine, Boston, MA, ²Lund University, Lund, Sweden
Background/Purpose: Oral NSAIDs are recommended for OA management. However, many patients with OA have contraindications to NSAIDs or have comorbidities that warrant precaution. Because few…
Abstract Number: 0736 • ACR Convergence 2021
Decrease in Prevalence of Self-Reported Anxiety or Depression in Persons with Osteoarthritis After Total Knee Arthroplasty: The BEST KNEE Cohort Study
Owen Krystia, Lauren King, Esther Waugh and Gillian Hawker, University of Toronto, Toronto, ON, Canada
Background/Purpose: While anxiety and depression are highly prevalent in persons with symptomatic knee osteoarthritis (OA), few studies have assessed the effect of treatment of knee…
Abstract Number: 1058 • ACR Convergence 2021
Sex-Specific Associations Between Knee Synovial Fluid Biomarkers and Knee Osteoarthritis Pain
Anthony Perruccio, Elizabeth Badley, J Denise Power, Mayilee Canizares, Nizar Mahomed, Kahlid Syed, Rajiv Gandhi, J. Roderick Davey, Mohit Kapoor, Christian Veillette and Y Raja Rampersaud, Schroeder Arthritis Institute, University Health Network, Toronto, ON, Canada
Background/Purpose: Sex has received limited attention in osteoarthritis (OA) clinical studies assessing relationships between biomarkers and pain. In prior work we reported sex-specific associations between…
Abstract Number: 1131 • ACR Convergence 2021
Interleukin 6 Concentration in Synovial Fluid and Its Clinical Significance
Ivars Veckalns and Anna Mihailova, Riga Stradins University, Riga, Latvia
Background/Purpose: Inflammatory arthritis (IA) treated with disease modifying antirheumatic drugs lead to secondary osteoarthritis (OA) due to inflammation, aging, and other factors. Inflammatory arthritis can…
Abstract Number: 1479 • ACR Convergence 2021
CD14, a Toll-like Receptor Co-Factor, Influences Osteoclast Differentiation and Activity, but Does Not Alter Osteoblastic Potential of Bone-Marrow Precursors in Mice
Jerahme Martinez, Vu Nguyen, Cheng Zhou, George Dodge and Carla Scanzello, University of Pennsylvania, philadelphia, PA
Background/Purpose: Changes in subchondral bone structure (SCB) occur in osteoarthritis (OA), and are visible by imaging as subchondral sclerosis on radiographs, and bone marrow lesions…
Abstract Number: 0215 • ACR Convergence 2021
Ultrasonographic Assessment of Knee Osteoarthritis and Its Agreement with Radiography
Khoa Nguyen¹ and Duc Tran², ¹Deparment of Rheumatology, Cho Ray Hospital, Ho Chi Minh City, Vietnam, ²Department of Rheumatology, Cho Ray Hospital, Ho Chi Minh, Vietnam
Background/Purpose: Ultrasonography (US) has been increasingly utilized for the assessment of various musculoskeletal conditions. However, the value of this tool in diagnosis of osteoarthritis (OA)…
Abstract Number: 0510 • ACR Convergence 2021
Fibrinogen Modified with Malondialdehyde-Acetaldehyde Adduct (MAA) And/or Citrulline (CIT) Induces Unique Cellular Responses in Human RA Synoviocytes
Brittany Wordekemper, Nozima Aripova, Michael Duryee, Eric Daubach, Bryant England, James O'Dell, Ted Mikuls and Geoffrey Thiele, University of Nebraska Medical Center, Omaha, NE
Background/Purpose: Malondialdehyde (MDA) is produced in response to oxidative stress and is associated with inflammation and disease pathogenesis. MDA can break down and form acetaldehyde…
Abstract Number: 0737 • ACR Convergence 2021
Enhanced Arthrocentesis of the Flexed Knee with Pneumatic Compression
Sumir Brahmbhatt¹, Ahsan Iqbal¹, Fatemeh Farshami², Maheswari Muruganandam³, Jaren Trost⁴, David Cisneros⁵, Adnan Kiani³, N. Suzanne Emil³, Sharon Nunez¹, William Hayward⁶, Philip Band⁷ and Wilmer Sibbitt³, ¹UNM, Albuquerque, NM, ²University of New Mexico, Albuquerque, MD, ³University of New Mexico, Albuquerque, NM, ⁴Optum, Albuquerque, NM, ⁵University of New Mexico School of Medicine, Albuquerque, NM, ⁶New Mexico Highlands University, Las Vegas, NM, ⁷NYU SOM, New York, NY
Background/Purpose: To explore an alternative to standard extended knee arthrocentesis using pneumatic compression of the flexed knee.Methods: Using a paired sample design, 41 consecutive effusive…
Abstract Number: 1059 • ACR Convergence 2021
The Association of Pain and Sleep in Relation to Depressive Symptoms Among Older Adults with Arthritis
Uyen-Sa Nguyen¹, Cameron Zielke² and Noah Peeri³, ¹University of North Texas Health Science Center, School of Public Health, Arlington, TX, ²University of Illinois-Chicago, Fort Worth, TX, ³University of North Texas Health Science Center, Fort Worth
Background/Purpose: The primary symptom of arthritis is chronic pain which has widespread consequences on an individual’s sleep and mental health. Research suggests that sleep and…
Abstract Number: 1132 • ACR Convergence 2021
Association Between Serum Selenium Level and the Prevalence of Osteoarthritis: Data from the Xiangya Osteoarthritis Study
Ning Wang¹, Mingsheng Xie¹, Chao Zeng², Tubao Yang¹, Zidan Yang¹, Yilun Wang¹, Jiatian Li¹, Jian Tian¹, Tuo Yang¹ and Guanghua Lei¹, ¹Central South University, Changsha, China (People's Republic), ²Central South University, Chang Sha, China (People's Republic)
Background/Purpose: Selenium plays an indispensable role in the process of antioxidant and antiinflammation. Oxidative stress and inflammation have been hypothesized to be involved in the…
Abstract Number: 1518 • ACR Convergence 2021
Elucidating Activated Osteoarthritis as an Emerging Immune Checkpoint Inhibitor Toxicity: A Descriptive Observational Study
Pankti Reid¹, David Liew², Rajshi Akruwala³, Anne Bass⁴ and Karmela Kim Chan⁵, ¹University of Chicago Medical Center, Chicago, IL, ²Austin Health, Heidelberg, Australia, ³SUNY Downstate Health Sciences University College of Medicine, Brooklyn, NY, ⁴Hospital for Special Surgery, Weill Cornell Medicine, New York, NY, ⁵Hospital for Special Surgery, New York, NY
Background/Purpose: Immune checkpoint inhibitors (ICIs) are a type of immunotherapy used for cancer management. ICI toxicities can challenge the ability to safely continue ICI therapy…

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