Abstracts tagged "osteoarthritis and pain"

Abstract Number: 335 • 2015 ACR/ARHP Annual Meeting
Prevalence of Hand Osteoarthritis and Factors Associated with Pain in Korean Farmers
Young Sun Suh¹, Yun-Hong Cheon¹, Hyun-Ok Kim¹, Ki-Soo Park², Hye Song Lim¹, Min-Gyu Jeon¹, Young-Sool Hah³ and Sang-Il Lee¹, ¹Division of Rheumatology, Department of Internal Medicine, Gyeongsang National University School of Medicine, Jinju, South Korea, ²Department of Preventive Medicine, Gyeongsang National University School of Medicine, Jinju, South Korea, ³Clinical Research Institute, Gyeongsang National University School of Medicine, Jinju, South Korea
Background/Purpose: Farming activity is burdened work with excessive use of hands. Thus, farmers are expected to have high prevalence of hand osteoarthritis (HOA). However, there…
Abstract Number: 1006 • 2015 ACR/ARHP Annual Meeting
Incident Frequent Knee Pain Is Associated with Changes in Semi-Quantitative Imaging Biomarkers of Inflammation
C.Kent Kwoh¹, Michael J. Hannon², Tomoko Fujii³, Frank W Roemer⁴, Ali Guermazi⁵, David Hunter⁶, Felix Eckstein⁷ and Robert M. Boudreau⁸, ¹Department of Medicine, The University of Arizona Arthritis Center and Division of Rheumatology, Tucson, AZ, ²Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, ³University of Pittsburgh, Pittsburgh, PA, ⁴Department of Radiology, Boston University School of Medicine, Boston, MA, ⁵Boston University School of Medicine, Boston, MA, ⁶Rheumatology, Institute of Bone and Joint Research, Kolling Institute, University of Sydney, Sydney, Australia, ⁷Paracelsus Med Univ, Chondrometrics GmbH, Salzburg, Austria, ⁸Epidemiology, University of Pittsburgh, Pittsburgh, PA
Background/Purpose: The cause of knee pain in osteoarthritis (OA) is multi-factorial, and there is increasing evidence of the role of inflammation in OA. The goal…
Abstract Number: 1018 • 2015 ACR/ARHP Annual Meeting
A 32-Mer Aggrecan Fragment Generated through Adamts-4/5 and MMP-Mediated Cleavage Can Directly Excite Nociceptive Neurons
Rachel E. Miller¹, Richard J. Miller², Abdelhak Belmadani³, Suzanne Golub⁴, Amanda J. Fosang⁴ and Anne-Marie Malfait⁵, ¹Biochemistry, Rush University Medical Center, Chicago, IL, ²Molecular Biochemistry and Pharmacology, Northwestern University, Chicago, IL, ³Northwestern University, Chicago, IL, ⁴University of Melbourne, Melbourne, Australia, ⁵Rush University Medeical Center, Chicago, IL
Background/Purpose: Cleavage of aggrecan in the interglobular domain (E373-374A) by ADAMTS-4/5 is an early event in osteoarthritis pathogenesis. Further cleavage by MMPs (N341-342F) releases a…
Abstract Number: 1301 • 2015 ACR/ARHP Annual Meeting
Pain Central Sensitization Assessed By Functional Magnetic Resonance Imaging in Patients with Knee Osteoarthritis
Jordi Monfort¹, Jesus Pujol², Marina Lopez³, Jone Llorente³, Gerard Martinez², Didac Macià², Francisco Montañés³, Miguel Angel Campillo³, Pedro Benito Ruiz⁴ and Joan Deus², ¹Rheumatology Department, Hospital del Mar, Barcelona, Spain, ²Magnetic Ressonance Imaging Unit, Barcelona, Spain, ³Rheumatology Department, Barcelona, Spain, ⁴Rheumatology Service, Hospital del Mar, Barcelona, Spain
Background/Purpose: An important aspect in chronic pain is central sensitization (CS) which involves increased responsiveness of the central neurons and it is clinically expressed like…
Abstract Number: 1431 • 2015 ACR/ARHP Annual Meeting
Age and Sex Impacts the Development of Hypersensitivity in the Murine Partial Medial Menisectomy Model of Osteoarthritis
Ada Delaney¹, Azar Barharpoor¹, Tianle Gao¹, Jie Su¹, NIlesh Agalave¹ and Camilla Svensson², ¹Dept. of Physiology & Pharmacology, Karolinska Institutet, Stockholm, Sweden, ²Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden
Background/Purpose: Osteoarthritis (OA) is the leading cause of chronic pain in European adults (37%; painineurope.com). Pain is the foremost symptom of OA, with both episodes…
Abstract Number: 2395 • 2015 ACR/ARHP Annual Meeting
Predictors of and Longitudinal Factors Associated with Change in Pain, Stiffness and Physical Function over 8 Years in a Midlife Cohort with a Low Prevalence of Knee Osteoarthritis
Hussain Ijaz Khan¹, Andrew McBride², Louisa Chou³, Dawn Aitken⁴, Leigh Blizzard⁵, Changhai Ding⁶, Jean-Pierre Pelletier⁷, Johanne Martel-Pelletier⁸, Flavia Cicuttini⁹ and Graeme Jones⁶, ¹Musculoskeletal Unit, Menzies Institute of Medical Research, Hobart, Australia, ²Musculoskeletal Unit, Menzies Institute of Medical Research, Hobart, 7000, Australia, ³Menzies Institute of Medical Research, University of Tasmania, Hobart, 7000, Australia, ⁴Muscyloskeletal Unit, Menzies Institute of Medical Research, Hobart, Australia, ⁵Biostatistics, Menzies Institute of Medical Research, Hobart, Australia, ⁶Musculoskeletal Unit, Menzies Institute for Medical Research, University of Tasmania, Hobart, Australia, ⁷Rheumatology, Institut de recherche en rhumatologie de Montréal (IRRM), Montréal, QC, Canada, ⁸Pharmacology, Osteoarthritis Research Unit, University of Montreal Hospital Research Centre (CRCHUM), Notre-Dame Hospital, Montreal, QC, Canada, ⁹Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Australia
Background/Purpose: Knee Osteoarthritis (OA) is the most common musculoskeletal condition affecting quality of life and was one of the leading causes of the years lived…
Abstract Number: 1281 • 2014 ACR/ARHP Annual Meeting
Knee Pain and a Prior Injury Are Associated with Increased Risk of a New Knee Injury: Data from the Osteoarthritis Initiative
Jeffrey B. Driban¹, Grace H. Lo², Lori Lyn Price³, Charles Eaton⁴, Bing Lu⁵ and Timothy E. McAlindon⁶, ¹Rheumatology, Tufts Medical Center, Boston, MA, ²VA HSR&D Center for Innovations in Quality, Effectiveness and Safety; Medical Care Line and Research Care Line; Department of Medicine, Michael E. DeBakey VA Medical Center, Baylor College of Medicine, Houston, TX, ³Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, MA, ⁴Center for Primary Care and Prevention, Memorial Hospital of Rhode Island, Providence, RI, ⁵Rheumatology, Brigham and Women's Hospital, Foxboro, MA, ⁶Division of Rheumatology, Tufts Medical Center, Boston, MA
Background/Purpose: A knee injury increases the risk for early-onset osteoarthritis (OA) and accelerated knee OA progression but little is known about risk factors for injuries…
Abstract Number: 1282 • 2014 ACR/ARHP Annual Meeting
Systemic Pain Modulation Is Related to Body Perception in People with Knee Osteoarthritis
Jennifer Stevens-Lapsley¹ and Andrew Kittelson², ¹Physical Therapy Program, UCD Physical Therapy Program, Aurora, CO, ²Rehabilitation Science PhD Program, University of Colorado Denver, Aurora, CO
Background/Purpose Cortically mediated changes in body perception have been linked to a variety of chronic pain conditions, including knee osteoarthritis (OA). However, associations between body…
Abstract Number: 1280 • 2014 ACR/ARHP Annual Meeting
Relationship of Buckling and Knee Injury to Pain Exacerbation in Knee Osteoarthritis: A Web-Based Case-Crossover Stud
Isabelle Zobel^1,2, Tahereh Erfani³, Kim Bennell⁴, Joanna Makovey³, Ben Metcalf⁴, Jian Sheng Chen⁵, Lyn March³, Yuqing Zhang⁶, Felix Eckstein⁷ and David J. Hunter³, ¹Institute of Anatomy, Paracelsus Medical University Salzburg, Salzburg, Austria, ²Institute of Bone and Joint Research, Kolling Institute, University of Sydney, St Leonards, Australia, ³Rheumatology, Institute of Bone and Joint Research, Kolling Institute, University of Sydney, Sydney, Australia, ⁴University of Melbourne, Melbourne, Australia, ⁵Rheumatology Royal North Shore Hospital, University of Sydney Institute of Bone and Joint Research, St Leonards, Australia, ⁶Boston University School of Medicine, Boston, MA, ⁷Anatomy & Musculoskeletal Research, Paracelsus Medical University, Salzburg, Austria
Background/Purpose Knee osteoarthritis (OA) pain is neither constant nor stable and exacerbations of pain are disabling. We examined whether knee injury and buckling (giving way)…
Abstract Number: 926 • 2014 ACR/ARHP Annual Meeting
Does a Family History of Total Knee Replacement for Knee Osteoarthritis Influence Knee Pain and Structural Progression? a Prospective Longitudinal Cohort Study
Feng Pan¹, Hussain Khan¹, Changhai Ding¹, Tania Winzenberg², Johanne Martel-Pelletier³, Jean-Pierre Pelletier³, Flavia Cicuttini⁴ and Graeme Jones¹, ¹Musculoskeletal Unit, Menzies Research Institute Tasmania, University of Tasmania, Hobart,7000, Australia, ²Menzies Research Institute Tasmania, University of Tasmania, Hobart,7000, Australia, ³Osteoarthritis Research Unit, University of Montreal Hospital Research Centre (CRCHUM), Notre-Dame Hospital, Montreal, QC, Canada, ⁴Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia
Background/Purpose: Genetic factors appear to play an important role in the pathogenesis of both knee pain and radiographic osteoarthritis (OA) based on cross-sectional studies but…
Abstract Number: 924 • 2014 ACR/ARHP Annual Meeting
Characteristics of Pain Flares in Knee Osteoarthritis
Susan L. Murphy¹, Angela K. Lyden², Arnold Gammaitoni³, David A. Williams⁴, Daniel J. Clauw⁵, J. Ryan Scott⁶ and Kristine Phillips⁷, ¹Physical Medicine & Rehabilitation, University of Michigan, Ann Arbor, MI, ²Department of Anesthesiology, University of Michigan, Ann Arbor, MI, ³Zogenix, Inc, San Diego, CA, ⁴Chronic Pain & Fatigue Rsch Ctr, Univ of MI Hlth System-Lobby M, Ann Arbor, MI, ⁵Anesthesiology/Internal Medicine (Rheum), University of Michigan, Ann Arbor, MI, ⁶Chronic Pain and Fatigue Research Center, University of Michigan, Ann Arbor, MI, ⁷Division of Rheumatology, University of Michigan, Ann Arbor, MI
Background/Purpose: For inclusion in osteoarthritis clinical trials, participants often need to have a pain ‘flare’, usually defined as a pain increase over a period of…
Abstract Number: 263 • 2014 ACR/ARHP Annual Meeting
Nutraceutical Products and Pain or Non-Pain Medications Use in Patients with Knee Osteoarthritis
Mei Chung¹, John B. Wong², Shaoyu Chang³ and Chenchen Wang⁴, ¹Department of Public Health and Community Medicine, Tufts University School of Medicine, Boston, MA, ²Medicine/Clinical Decision Making, Tufts Medical Center, Boston, MA, ³Tufts Medical Center, Boston, MA, ⁴Rheumatology, Tufts Medical Center, Boston, MA
Background/Purpose: Knee osteoarthritis (OA) causes substantial health burden and economic costs including medications and neutraceuticals for pain. The aim of this analysis was to describe…
Abstract Number: 220 • 2014 ACR/ARHP Annual Meeting
Lower Extremity Presarcopenia Is Associated with the Severity of Knee Pain
Yun-Hong Cheon¹, Wan-Hee Yoo², Young Sun Suh³, Hyun-Ok Kim³, Ki-Soo Park⁴, Sang-Il Lee³ and Hye-Ji Jeon⁴, ¹Rheumatology, Department of Internal Medicine, Chonbuk National University Medical School and Research Institute of Clinical Medicine, Jeonju, South Korea, ²Division of Rheumatology, Department of Internal Medicine, Chonbuk National University School of Medicine, Jeonju, South Korea, ³Division of Rheumatology, Department of Internal Medicine, Gyeongsang National University School of Medicine, Jinju, South Korea, ⁴Department of Preventive Medicine, Gyeongsang National University School of Medicine, Jinju, South Korea
Background/Purpose Presarcopenia, which is defined as skeletal muscle mass loss, and knee pain have been gained attention with ageing. Little is known about the association…
Abstract Number: 216 • 2014 ACR/ARHP Annual Meeting
Hip Adiposity, Not Local Knee Adiposity, Is Associated with Knee Pain Independent of Radiographic Osteoarthritis Severity
Grace H. Lo¹, Ajay Balasubramanyam², Jeffrey B. Driban³, Lori Lyn Price⁴, Charles B. Eaton⁵ and Timothy E. McAlindon⁶, ¹VA HSR&D Center for Innovations in Quality, Effectiveness and Safety; Medical Care Line and Research Care Line; Department of Medicine, Michael E. DeBakey VA Medical Center, Baylor College of Medicine, Houston, TX, ²Medicine, Baylor College of Medicine, Houston, TX, ³Tufts Medical Center, Boston, MA, ⁴Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, MA, ⁵Family Medicine, Memorial Hospital of Rhode Island, Pawtucket, RI, ⁶Division of Rheumatology, Tufts Medical Center, Boston, MA
Background/Purpose Elevated body mass index (BMI) is associated with pain in knee OA. However, it is unclear if adiposity closer in proximity to the knee…
Abstract Number: 2783 • 2014 ACR/ARHP Annual Meeting
Effect of Synovitis, Effusion and Bone Marrow Lesions on Development of Sensitization in Knee OA: The Multicenter Osteoarthritis Study
Tuhina Neogi¹, Michael C. Nevitt², Joachim Scholz³, Lars Arendt-Nielsen⁴, Clifford Woolf⁵, Laurence A. Bradley⁶, Emily K. Quinn⁷ and Laura Frey-Law⁸, ¹Boston University School of Medicine, Boston, MA, ²Epidemiology & Biostatistics, UCSF (University of California, San Francisco), San Francisco, CA, ³Columbia University, New York, NY, ⁴Department of Health Science and Technology, Faculty of Medicine, Aalborg University, Center for Sensory-Motor Interaction, Aalborg, Denmark, ⁵F.M. Kirby Neurobiology Center, Children's Hospital Boston, Boston, MA, ⁶Div of Rheumatology, Univ of Alabama-Birmingham, Birmingham, AL, ⁷Clinical Epidemiology Unit, Boston University, Boston, MA, ⁸University of Iowa, Iowa City, IA
Background/Purpose: Alterations in the peripheral and central nervous systems including sensitization are thought to play an important role in the pain experience in knee OA.…

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Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. Academic institutions, private organizations and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part a scientific presentation or presentation of additional new information that will be available at the time of the meeting) is under embargo until Saturday, November 11, 2023.

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