Abstract Number: L04 • ACR Convergence 2024
Performance of an Artificial Intelligence Model Compared to Multiple Human Experts in Scoring Synovitis Severity and Osteophyte Severity on Joint Ultrasound Images
Background/Purpose: To evaluate the agreement of an artificial intelligence (AI) model designed to assess greyscale and Doppler synovitis severity and osteophyte severity in hand joints…Abstract Number: L08 • ACR Convergence 2024
A Phase 2b, Randomized, Double-blind, Placebo-controlled, Dose-ranging and Parallel-group Study to Evaluate the Safety and Efficacy of XG005 in Subjects with Painful Osteoarthritis of the Knee
Background/Purpose: Osteoarthritis (OA) affects 595 million people globally; cases are projected to increase 49-95% for various joints by 2050 as populations age (GBD 2023). OA…Abstract Number: L15 • ACR Convergence 2024
LEVI-04, a Novel neurotrophin-3 Inhibitor, Substantially Improves Pain and Function Without Deleterious Effects on Joint Structure in People with Knee Osteoarthritis: A Randomized Controlled Phase II Trial
Background/Purpose: There is an urgent need for new therapies to treat OA. Excess neurotrophins (NT) are implicated in OA and other painful conditions. Previous OA…Abstract Number: 0028 • ACR Convergence 2024
Human Meniscus Histopathological and Transcriptomic Changes at Early and Advanced Stages of Knee Osteoarthritis
Background/Purpose: The knee menisci are essential elements in joint biomechanics and meniscus damage is a driver of cartilage destruction and knee osteoarthritis. Meniscus damage and…Abstract Number: 0852 • ACR Convergence 2024
3-dimensional Shape Changes of the Knee over 4 Years Are Linear and Progressive but Much More Rapid in Osteoarthritic Joints: Data from the Osteoarthritis Initiative
Background/Purpose: The specific bony changes of osteophyte growth and “bone attrition” (broadening and flattening of the femoral condyles) associated with OA have been recognized in…Abstract Number: 1180 • ACR Convergence 2024
Relationship Between Changes in Physical Activity and Early Onset Knee Osteoarthritis in Individuals After ACL Reconstruction
Background/Purpose: Low physical activity levels are associated with osteoarthritis (OA) development and progression in individuals at risk for OA development. Including both structural and symptomatic…Abstract Number: 1198 • ACR Convergence 2024
Impact of Metabolic Syndrome on Knee Osteoarthritis Severity and Progression: A PROCOAC Cohort Study
Background/Purpose: The contribution of metabolic factors to the development of osteoarthritis (OA) has not been fully elucidated. The aim of this study is to analyze…Abstract Number: 1292 • ACR Convergence 2024
Primary Care Provider Educational Tool to Improve Osteoarthritis Management in the Primary Care Setting
Background/Purpose: Osteoarthritis is the most common form of arthritis and its prevalence is increasing. As a non-inflammatory type of arthritis, it can be managed in…Abstract Number: 1906 • ACR Convergence 2024
Bayesian Algorithm to Identify Osteoarthritis in Administrative Health Data Without Requiring Chart Review
Background/Purpose: Osteoarthritis (OA) is the most prevalent arthritis and a significant contributor to Years Lived with Disability. Administrative health data are widely used to study…Abstract Number: 2094 • ACR Convergence 2024
Cross-sectional Associations of Radiographic Multiple Joint Osteoarthritis and Pain with Demographic and Clinical Characteristics: Design of a Multi-modal Study in Human and Pet Dogs
Background/Purpose: Multiple joint osteoarthritis (MJOA) is a progressive, highly prevalent disease affecting millions of Americans and as well as pet dogs. This preliminary analysis sought…Abstract Number: 2110 • ACR Convergence 2024
Association Between Symptomatic Knee Osteoarthritis and Blood Glucose Control in Persons with Type 2 Diabetes
Background/Purpose: There is a high prevalence of knee osteoarthritis (OA) in people with type 2 diabetes (T2D), and knee OA increases risk for diabetes complications…Abstract Number: 0029 • ACR Convergence 2024
Effect of Metformin on the Incidence of Total Knee Replacement: A Systematic Review and Meta-Analysis
Background/Purpose: Osteoarthritis (OA) is among the most common debilitating conditions, causing disability and pain in older adults. For end-stage OA, total knee replacement (TKR) is…Abstract Number: 0861 • ACR Convergence 2024
Stem Cell Function and Capsule Tissue Composition Are Associated with Symptoms, Joint Range of Motion and Radiographic Severity in People with Knee Osteoarthritis
Background/Purpose: Osteoarthritis is a common and debilitating condition without cure. Increased OA severity is associated with lost range of motion (ROM) in the affected joint.…Abstract Number: 1183 • ACR Convergence 2024
The Effectiveness of Orthosis for the Management of Hand Osteoarthritis-a Systemic Review and Meta-analysis
Background/Purpose: Hand osteoarthritis (OA) affects 11-33% of men and women in their 50s and 60s, significantly affecting the quality of life of those afflicted.Orthoses are…Abstract Number: 1199 • ACR Convergence 2024
Diclofenac Sodium 1% Gel Improves Physical Function in the Performance of Important Activities of Daily Living in Patients with Hand or Knee Osteoarthritis
Background/Purpose: Osteoarthritis (OA) is the most common form of arthritis, with hand and knee being among the most afflicted joints. Symptoms of OA include joint…
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