Abstract Number: 0466 • ACR Convergence 2024
Inpatient Outcomes of Rheumatoid Arthritis in Hospitalized Patients Using Cannabis: Data from the National Inpatient Sample
Background/Purpose: Despite advancements in rheumatoid arthritis (RA) treatment, effective pain management remains challenging, with many patients also experiencing insomnia, anxiety, and depression. As cannabis legalization…Abstract Number: 1209 • ACR Convergence 2024
Time to Knee Replacement by Kellgren-Lawrence Grade and Presence of Frequent Knee Pain in Two Large and Diverse Longitudinal Cohorts: Data from MOST and OAI
Background/Purpose: Receipt of knee replacement has been proposed by the FDA as a structural and symptom outcome for clinical trials of Disease Modifying Osteoarthritis Drugs…Abstract Number: 1665 • ACR Convergence 2024
Multicenter Randomized Controlled Trial of Physical Therapy (PT) or Sham PT in Persons with Knee Pain, Meniscal Tear, and Osteoarthritic Imaging Changes
Background/Purpose: The syndrome of knee pain and meniscal tear (MT) is prevalent and disabling. The TeMPO trial (Treatment of Meniscal Problems in Osteoarthritis (OA)) compares…Abstract Number: 1669 • ACR Convergence 2024
Will Investigators Enroll? A Vignette Study to Gauge Investigator Equipoise in a Trial of Surgery vs. Nonoperative Therapy in Subjects with Meniscal Tear and Persistent Pain Following Physical Therapy
Background/Purpose: Clinician investigators may be unwilling to enroll all eligible subjects into randomized controlled trials (RCTs) because they feel certain subjects would benefit more from…Abstract Number: 1964 • ACR Convergence 2024
Comparison of Knee Minimum Joint Space Width Measurements Using Deep Learning in Patients with Rheumatoid Arthritis and Osteoarthritis Undergoing Total Knee Arthroplasty
Background/Purpose: While large joint damage is a hallmark of both Osteoarthritis (OA) and Rheumatoid Arthritis (RA), the mechanisms of degradation are substantially different. Minimum joint…Abstract Number: 2158 • ACR Convergence 2024
An MVPA Is MVPA Is MVPA, or Is It? Impact of the Definition of Moderate to Vigorous Physical Activity (MVPA) on Its Amount in Persons with Advanced Knee Osteoarthritis
Background/Purpose: ActiGraph is a gold standard for MVPA assessment with several counts per minute (CPM) validated thresholds proposed to measure MVPA. Historically, these thresholds have…Abstract Number: 1974 • ACR Convergence 2023
Comparison of Gait Spatiotemporal Measures Between Patients with Insertional Achilles Tendinopathy or Midportion Achilles Tendinopathy
Background/Purpose: Insertional and midportion Achilles tendinopathy (AT) are painful injuries affecting both active and sedentary populations. Patients with AT present with pain with loading, often…Abstract Number: 2521 • ACR Convergence 2023
Understanding Age as a Risk Factor for Complications After Total Knee Arthroplasty: What Can We Learn from Machine Learning?
Background/Purpose: Rates of total knee arthroplasty (TKA) in the United Stateshave risen, coupled with increasing demand for TKAs in younger patients.1Althoughrates of postoperative complications in…Abstract Number: 2525 • ACR Convergence 2023
Comparing Patellar Tendon Characteristics Between Adults with and Without Knee Pain
Background/Purpose: Knee pain is one of the most common types of joint pain leading to disability, limited physical activity, and reduced quality of life. While…Abstract Number: 2526 • ACR Convergence 2023
Single-cell RNA Sequencing Reveals the CRTAC1+ Population Actively Contributes to the Pathogenesis of Spinal Ligament Degeneration by Inducing Macrophage Activation
Background/Purpose: Spinal ligament degeneration is a chronic disease that affects the spine, ligaments, and associated bones, resulting in back pain and functional limitations in the…Abstract Number: 0167 • ACR Convergence 2023
Healthcare Resource Utilization Associated with Tumor-Induced Osteomalacia: Review of Patient Histories Prior to Entry in Clinical Trial UX023T-CL201
Background/Purpose: Tumor-induced osteomalacia (TIO) is an ultra-rare paraneoplastic disorder, characterized by renal phosphate wasting due to increased production of fibroblast growth factor 23 (FGF23). Chronic…Abstract Number: 0859 • ACR Convergence 2023
Single Injection AAV2-hFGF18 Demonstrates Superior Safety and Efficacy over Repeat rhFGF18 Protein Injections in a Model of Induced Osteoarthritis
Background/Purpose: Osteoarthritis (OA) is the largest unmet need in rheumatology, affecting 1 in 7 adults, with no approved disease modifying treatments. A recent placebo-controlled clinical…Abstract Number: 0883 • ACR Convergence 2023
The Role of Plasmin and Fibrinolysis Pathways in Osteoarthritis
Background/Purpose: Osteoarthritis (OA) is the major cause of joint failure. Increasing evidence suggests that activation of fibrinolysis is involved in the pathogenesis of OA. Here…Abstract Number: 0502 • ACR Convergence 2022
The Effect of Osteoporosis on Developing Vertebral Compression Fracture After Single-level Posterior Lumbar Fusion Surgery: A Large Healthcare Claims Database Study
Background/Purpose: Vertebral compression fracture (VCF) is a significant osteoporosis-related complication (ORC) associated with instrumented spinal fusion. Various studies have assessed the development of VCF in…Abstract Number: 0835 • ACR Convergence 2022
Temporal Trends in Prosthetic Joint Infection
Background/Purpose: Prosthetic joint infection (PJI) is a dreaded complication of total knee replacement (TKR) that usually requires removal of the prosthesis, treatment with antibiotics and…