ACR Meeting Abstracts

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Abstracts tagged "Orthopedics"

  • Abstract Number: 0466 • ACR Convergence 2024

    Inpatient Outcomes of Rheumatoid Arthritis in Hospitalized Patients Using Cannabis: Data from the National Inpatient Sample

    Karun Shrestha1, Prakriti Subedi2, Manoj Ghimire3, Sajana Poudel4, Keerthi Parvathaneni5, Mahmoud Hashim6, Kalpana Ghimire5, Oshna Pandey5, Mohammed Hasan7, Clement Tagoe8 and Liliya Gandrabur9, 1St. Barnabas Hospital Internal Medicine Residency, Bronx, NY, 2St. Barnabas Hospital, Bronx, NY, 3St Barnabas Hospital, BRONX, NY, 4Cook County Health, CHICAGO, NY, 5Department of Internal Medicine, St. Barnabas Hospital, SBH Health System, Bronx, NY 10457, USA, Bronx, NY, 6SBH Health System, New Rochelle, NY, 7Parkview Medical Center, Pueblo, CO, 8Albert Einstein College of Medicine, FRESH MEADOWS, NY, 9SBH Health System, Forest Hills, NY

    Background/Purpose: Despite advancements in rheumatoid arthritis (RA) treatment, effective pain management remains challenging, with many patients also experiencing insomnia, anxiety, and depression. As cannabis legalization…
  • Abstract Number: 1209 • ACR Convergence 2024

    Time to Knee Replacement by Kellgren-Lawrence Grade and Presence of Frequent Knee Pain in Two Large and Diverse Longitudinal Cohorts: Data from MOST and OAI

    Kent Kwoh1, Rongrong Tang2, Edward Bedrick3, Jeffery Duryea4, Zong-Ming Li2, Jean Liew5, Xiaoxiao Sun6 and Tuhina Neogi5, 1University of Arizona, Tucson, AZ, 2University of Arizona Arthritis Center, University of Arizona College of Medicine - Tucson, Tucson, AZ, 3Department of Epidemiology andBiostatistics, Mel and Enid Zuckerman College of Public Health, University of Arizona, Tucson, 4Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, 5Boston University Chobanian & Avedisian School of Medicine, Boston, MA, 6Department of Biostatistics, Mel and Enid Zuckerman College of Public Health, University of Arizona, Tucson, AZ

    Background/Purpose:  Receipt of knee replacement has been proposed by the FDA as a structural and symptom outcome for clinical trials of Disease Modifying Osteoarthritis Drugs…
  • Abstract Number: 1665 • ACR Convergence 2024

    Multicenter Randomized Controlled Trial of Physical Therapy (PT) or Sham PT in Persons with Knee Pain, Meniscal Tear, and Osteoarthritic Imaging Changes

    Jeffrey Katz1, Jamie Collins2, Leslie Bisson3, Faith Selzer4, Morgan Jones2, Heidi Yang2, James Irrgang5, Clare Safran-Norton2, Kurt Spindler6 and Elena Losina2, 1Brigham and Women's Hospital, Brookline, MA, 2Brigham and Women's Hospital, Boston, MA, 3University at Buffalo, Buffalo, NY, 4Brigham and Women's Hospital, Amesbury, MA, 5University of Pittsburgh, Pittsburgh, PA, 6Cleveland Clinic, Clev, OH

    Background/Purpose: The syndrome of knee pain and meniscal tear (MT) is prevalent and disabling. The TeMPO trial (Treatment of Meniscal Problems in Osteoarthritis (OA)) compares…
  • Abstract Number: 1669 • ACR Convergence 2024

    Will Investigators Enroll? A Vignette Study to Gauge Investigator Equipoise in a Trial of Surgery vs. Nonoperative Therapy in Subjects with Meniscal Tear and Persistent Pain Following Physical Therapy

    Jeffrey Katz1, Faith Selzer2, Katharine Fox3, Jon Dhani3, Kyna Long3, Andrea Carland4, Tiffany Thavison4, Leslie Bisson4, Morgan Jones3, Katherine Krupa3 and Nomi Weiss-laxer5, 1Brigham and Women's Hospital, Brookline, MA, 2Brigham and Women's Hospital, Amesbury, MA, 3Brigham and Women's Hospital, Boston, MA, 4University at Buffalo, Buffalo, NY, 5U, Buffalo, NY

    Background/Purpose: Clinician investigators may be unwilling to enroll all eligible subjects into randomized controlled trials (RCTs) because they feel certain subjects would benefit more from…
  • Abstract Number: 1964 • ACR Convergence 2024

    Comparison of Knee Minimum Joint Space Width Measurements Using Deep Learning in Patients with Rheumatoid Arthritis and Osteoarthritis Undergoing Total Knee Arthroplasty

    Kellen Mulford1, Elizabeth Kaji1, Austin Grove1, Ronnie Sebro2, Cody Wyles1, John Davis1 and Cynthia Crowson1, 1Mayo Clinic, Rochester, MN, 2Mayo Clinic, Jacksonville, FL

    Background/Purpose: While large joint damage is a hallmark of both Osteoarthritis (OA) and Rheumatoid Arthritis (RA), the mechanisms of degradation are substantially different. Minimum joint…
  • Abstract Number: 2158 • ACR Convergence 2024

    An MVPA Is MVPA Is MVPA, or Is It? Impact of the Definition of Moderate to Vigorous Physical Activity (MVPA) on Its Amount in Persons with Advanced Knee Osteoarthritis

    Samantha Chin1, Jamie Collins1, Jeffrey Katz2, Dorothy Dunlop3, Lauren Mitchell1, Rowland Chang4, Khara James1, Christine Pellegrini5, Jason Kim6, Katharine Fox1, Anne Holleman1 and Elena Losina1, 1Brigham and Women's Hospital, Boston, MA, 2Brigham and Women's Hospital, Brookline, MA, 3Northwestern University, New Haven, CT, 4Northwestern University Division of Rheumatology, Chicago, IL, 5University of South Carolina, Columbia, SC, 6Arthritis Foundation, Atlanta, GA

    Background/Purpose: ActiGraph is a gold standard for MVPA assessment with several counts per minute (CPM) validated thresholds proposed to measure MVPA. Historically, these thresholds have…
  • Abstract Number: 0167 • ACR Convergence 2023

    Healthcare Resource Utilization Associated with Tumor-Induced Osteomalacia: Review of Patient Histories Prior to Entry in Clinical Trial UX023T-CL201

    Suzanne Jan de Beur1, Thomas Carpenter2, Kathryn Dahir3, Erik Imel4, María Belén Zanchetta5, Angela Williams6, Zhiyi Li7, Matthew Sharp6 and Ben Johnson6, 1Johns Hopkins University School of Medicine, Baltimore, MD, 2Yale School of Medicine, New Haven, CT, 3Vanderbilt University Medical Center, Nashville, TN, 4Indiana University School of Medicine, Indianapolis, IN, 5Universidad del Salvador, Buenos Aires, Argentina, 6Kyowa Kirin International, Marlow, United Kingdom, 7Kyowa Kirin North America, Bedminster, NJ

    Background/Purpose: Tumor-induced osteomalacia (TIO) is an ultra-rare paraneoplastic disorder, characterized by renal phosphate wasting due to increased production of fibroblast growth factor 23 (FGF23). Chronic…
  • Abstract Number: 0859 • ACR Convergence 2023

    Single Injection AAV2-hFGF18 Demonstrates Superior Safety and Efficacy over Repeat rhFGF18 Protein Injections in a Model of Induced Osteoarthritis

    Alex Goraltchouk1, Judith Hollander2, Francesco Luppino3, Li Zeng2 and Alexey Seregin3, 1Remedium Bio, Inc, Needham, MA, 2Tufts University, Boston, MA, 3Remedium Bio, Inc., Needham, MA

    Background/Purpose: Osteoarthritis (OA) is the largest unmet need in rheumatology, affecting 1 in 7 adults, with no approved disease modifying treatments. A recent placebo-controlled clinical…
  • Abstract Number: 0883 • ACR Convergence 2023

    The Role of Plasmin and Fibrinolysis Pathways in Osteoarthritis

    Qian Wang, heidi Wong, Audrey Bai, Zelda Love, Constance Chu and William Robinson, Stanford School of Medicine, Stanford, CA

    Background/Purpose: Osteoarthritis (OA) is the major cause of joint failure. Increasing evidence suggests that activation of fibrinolysis is involved in the pathogenesis of OA. Here…
  • Abstract Number: 1974 • ACR Convergence 2023

    Comparison of Gait Spatiotemporal Measures Between Patients with Insertional Achilles Tendinopathy or Midportion Achilles Tendinopathy

    Hayley Smitheman1, Kayla Seymore1, Andy Smith1, Morgan Potter1, Nabeel Alghamdi1 and Karin Silbernagel2, 1University of Delaware, Newark, DE, 2University of Delaware, Avondale, PA

    Background/Purpose: Insertional and midportion Achilles tendinopathy (AT) are painful injuries affecting both active and sedentary populations. Patients with AT present with pain with loading, often…
  • Abstract Number: 2521 • ACR Convergence 2023

    Understanding Age as a Risk Factor for Complications After Total Knee Arthroplasty: What Can We Learn from Machine Learning?

    Bella Mehta1, Yi Yiyuan2, Chloe Heiting3, Kaylee Ho2, Susan Goodman3, Peter Sculco3, Fei Wang2, Rich Caruana4, Peter cram5 and Said Ibrahim6, 1Hospital for Special Surgery, Weill Cornell Medicine, New York, NY, 2Weill Cornell Medicine, New York, NY, 3Hospital for Special Surgery, New York, NY, 4Microsoft, Redmond, WA, 5The University of Texas Medical Branch, Galveston, TX, 6Northwell Health, New Hyde Park, NY

    Background/Purpose: Rates of total knee arthroplasty (TKA) in the United Stateshave risen, coupled with increasing demand for TKAs in younger patients.1Althoughrates of postoperative complications in…
  • Abstract Number: 2525 • ACR Convergence 2023

    Comparing Patellar Tendon Characteristics Between Adults with and Without Knee Pain

    Samantha Price1, Karin Silbernagel2, David Felson3, Joshua Stefanik4 and Patrick Corrigan1, 1Saint Louis University, St. Louis, MO, 2University of Delaware, Avondale, PA, 3Boston University, Boston, MA, 4Northeastern University, Boston, MA

    Background/Purpose: Knee pain is one of the most common types of joint pain leading to disability, limited physical activity, and reduced quality of life. While…
  • Abstract Number: 2526 • ACR Convergence 2023

    Single-cell RNA Sequencing Reveals the CRTAC1+ Population Actively Contributes to the Pathogenesis of Spinal Ligament Degeneration by Inducing Macrophage Activation

    Yulong Tang1, Dachun Zhuo1, Li Jin1, Qi Zhu2, Yuanyuan Chen3, Jiucun Wang4 and Jing Liu4, 1Fudan University, Shanghai, China, 2Guanghua Integrative Medicine Hospital, Shanghai, China, 3Shanghai Sixth People's Hospital, Shanghai, China, 4Shanghai, Shanghai, China

    Background/Purpose: Spinal ligament degeneration is a chronic disease that affects the spine, ligaments, and associated bones, resulting in back pain and functional limitations in the…
  • Abstract Number: 0502 • ACR Convergence 2022

    The Effect of Osteoporosis on Developing Vertebral Compression Fracture After Single-level Posterior Lumbar Fusion Surgery: A Large Healthcare Claims Database Study

    Vartika Kesarwani1, Sean Esmende2, Regina Kostyun2, Matthew Solomito2, Heeren Makanji2, John Magaldi2 and Mandeep Kumar2, 1University of Connecticut, Farmington, CT, 2Bone and Joint Institute, Hartford Hospital, Hartford, CT

    Background/Purpose: Vertebral compression fracture (VCF) is a significant osteoporosis-related complication (ORC) associated with instrumented spinal fusion. Various studies have assessed the development of VCF in…
  • Abstract Number: 0835 • ACR Convergence 2022

    Temporal Trends in Prosthetic Joint Infection

    Anne Bass1, Yi Zhang,2, Peter Sculco2, huong do2, Kayla Glaser2, alberto Carli2, Mark Figgie2 and Susan Goodman2, 1Hospital for Special Surgery/Weill Cornell Medicine, New York, NY, 2Hospital for Special Surgery, New York, NY

    Background/Purpose: Prosthetic joint infection (PJI) is a dreaded complication of total knee replacement (TKR) that usually requires removal of the prosthesis, treatment with antibiotics and…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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