Abstracts tagged "obesity"

Abstract Number: 36 • 2017 Pediatric Rheumatology Symposium
The Association of Obesity with Pediatric Psoriatic Arthritis
Cynthia Manos¹, Rui Xiao², Timothy G. Brandon¹, Alexis Ogdie-Beatty³ and Pamela Weiss⁴, ¹Rheumatology, Children's Hospital of Philadelphia, Philadelphia, PA, ²Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, PA, ³Rheumatology, Hospital of the University of Pennsylvania, Philadelphia, PA, ⁴Division of Rheumatology, Center for Pediatric Clincial Effectiveness, Children's Hospital of Philadelphia, Philadelphia, PA
Background/Purpose: Obesity is associated with a significantly increased risk of inflammatory arthritis in adult patients with psoriasis. Obese adults with psoriatic arthritis (PsA) also…
Abstract Number: 2352 • 2016 ACR/ARHP Annual Meeting
Obesity-Related Systemic Inflammation and Knee Synovitis
Devyani Misra¹, Tuhina Neogi², Michael C. Nevitt³, James Torner⁴, Cora E. Lewis⁵ and David T. Felson⁶, ¹Medicine, Section of, BUSM, Boston, MA, ²Clinical Epidemiology, BUSM, Boston, MA, ³Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, ⁴University of Iowa, UIowa, Iowa City, IA, ⁵University of Alabama Birmingham, Birmingham, AL, ⁶Clinical Epidemiology Unit, Boston University School of Medicine, Boston, MA
Background/Purpose: Obesity, a major risk factor for knee osteoarthritis (OA), is a state of systemic inflammation through elaboration of adipokines (pro and anti-inflammatory cytokines) from…
Abstract Number: 2369 • 2016 ACR/ARHP Annual Meeting
Obesity and Severity of Joint Space Narrowing Are Associated with Viscosupplementation Failure in Patients with Knee Osteoarthritis. Post-Hoc Analysis of a Double-Blind, Controlled, Multicentre, Randomized Trial
Florent Eymard¹, Xavier Chevalier² and Thierry Conrozier³, ¹Department of Rheumatology, APHP Henri Mondor Hospital, Paris, France, ²Rheumatology, Hopital Henri Mondor, Créteil, France, ³Department of Rheumatology,, Nord Franche-Comté Hospital, Belfort, France
Background/Purpose: Viscosupplementation (VS) is still controversial. One of the key points is the lack of well-identified factors of response. We aimed to identify clinical…
Abstract Number: 2996 • 2016 ACR/ARHP Annual Meeting
High Fat Diet-Induced Osteoarthritis Progression Is Dependent on Toll-like Receptor 4
Mary Beth Humphrey¹, Evangelia Kalaitzoglou², Camille Herron², Yanqing HU², Yao Fu³, Erika Barboza Prado Lopes³, Elise Donovan³, Joanna Hudson³ and Timothy Griffin³, ¹Medicine/Rheumatology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, ²Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK, ³Aging and Metabolism, Oklahoma Medical Research Foundation, Oklahoma City, OK
Background/Purpose: Obesity is considered the primary preventable risk factor for OA, increasing the risk of developing OA in weight-bearing joints, especially the knee, as…
Abstract Number: 3069 • 2016 ACR/ARHP Annual Meeting
Weight Loss in the Early Rheumatoid Arthritis Period Is Associated with Subsequent Increased Mortality in RA Patients and Matched Comparators: Evidence Against an RA-Specific Obesity Paradox
Jeffrey A. Sparks¹, Shun-Chiao Chang², Uyen Sa D.T. Nguyen^3,4, Medha Barbhaiya², Sara K. Tedeschi², Bing Lu², Karen H. Costenbader², Yuqing Zhang⁵, Hyon K. Choi⁶ and Elizabeth W. Karlson², ¹Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, ²Rheumatology, Immunology and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, ³Orthopedics and Physical Rehabilitation, University of Massachusetts Medical School, Worcester, MA, ⁴Boston University School of Medicine, Boston, MA, ⁵Clinical Epidemiology and Training Unit, Boston University School of Medicine, Boston, MA, ⁶Rheumatology, Allergy and Immunology, Massachusetts General Hospital and Harvard Medical School, Boston, MA
Background/Purpose : Weight loss may explain the obesity paradox for mortality, since those who unintentionally lose weight to reach normal BMI may have higher mortality…
Abstract Number: 3087 • 2016 ACR/ARHP Annual Meeting
Association of Weight Loss with Improved Disease Activity in Patients with Rheumatoid Arthritis
David J. Kreps^1,2, Florencia Halperin³, Sonali P. Desai³, Zhi Zhang³, Elena Losina³, Elizabeth W. Karlson¹, Bonnie L. Bermas¹ and Jeffrey A. Sparks⁴, ¹Rheumatology, Immunology and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, ²Boston University, Boston, MA, ³Division of Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, ⁴Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA
Background/Purpose : Obesity has been associated with worsened RA outcomes and increased disease activity. However, few longitudinal studies have investigated whether weight loss might improve…
Abstract Number: 3193 • 2016 ACR/ARHP Annual Meeting
Is an Intensive Diet and Exercise Regimen Cost-Effective for Obese and Overweight Patients with Symptomatic Knee OA?
Elena Losina¹, Karen C. Smith², A. David Paltiel³, Lisa Gale Suter⁴, Jeffrey N. Katz⁵ and Stephen P. Messier⁶, ¹Orthopedics, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, ²Orthopaedics, Brigham and Women's Hospital, Boston, MA, ³Yale University, New Haven, CT, ⁴Medicine, Rheumatology, Yale University, New Haven, CT, ⁵Orthopaedics, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, ⁶Department of Health and Exerc, Wake Forest University, Winston-Salem, NC
Background/Purpose: About 50% of persons with knee OA are obese. Quality-adjusted life-year losses due to knee OA and obesity exceed 3.5 per person. The results…
Abstract Number: 397 • 2016 ACR/ARHP Annual Meeting
Comorbidities Associated with Pediatric Psoriatic Arthritis
Cynthia Manos¹, Rui Xiao², Alexis Ogdie³, Timothy Brandon⁴ and Pamela F. Weiss^5,6, ¹Rheumatology, Children's Hospital of Philadelphia, Philadelphia, PA, ²Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, PA, ³University of Pennsylvania, Philadelphia, PA, ⁴Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA, ⁵Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, ⁶Division of Rheumatology, Center for Pediatric Clincial Effectiveness, Children's Hospital of Philadelphia, Philadelphia, PA
Background/Purpose: In adults, psoriatic arthritis (PsA) is associated with an increased prevalence of obesity, hypertension, and diabetes. It is not yet known if pediatric patients…
Abstract Number: 1194 • 2016 ACR/ARHP Annual Meeting
Low Body Mass Index and Smoking Are Associated with a Lower Risk of Sarcoidosis: A Population-Based Nested Case-Control Study
Patompong Ungprasert¹, Cynthia S. Crowson² and Eric L. Matteson¹, ¹Rheumatology, Mayo Clinic, Rochester, MN, ²Health Sciences Research, Mayo Clinic, Rochester, MN
Low Body Mass Index and Smoking Are Associated With a Lower Risk of Sarcoidosis: A Population-Based Nested Case-Control Study Background/Purpose: Sarcoidosis is a systemic disorder…
Abstract Number: 1543 • 2016 ACR/ARHP Annual Meeting
Obese Patients with RA Have a More Seropositive and a More Active Disease with Less Deformities
Adeeba Al-Herz¹, Adel Al-Awadhi², Khulood Saleh³, Waleed Al-Kandari³, Eman Hasan⁴, Aqeel Ghanem⁵, Fatemah Abutiban⁶, Ahmad Alenizi⁶, Mohammad Hussain⁴, Yaser Ali⁵, Ibrahim Nahar⁵, Ali Aldei¹, Hebah Alhajeri⁵, Sawsan Hayat⁵, Ahmad Khadrawy³, Ammad Fazal³, Khaled Mokaddem¹, Ajaz Zaman⁵, Ghada Mazloum⁵, Youssef Bartella¹, Sally Hamed¹ and Ahmed Al-Saber⁷, ¹Rheumatology, Al-Amiri Hospital, Kuwait city, Kuwait, ²Faculty of Medicine, Kuwait, Kuwait, ³Rheumatology, Farwania Hospital, Farwania, Kuwait, ⁴Al-Amiri Hospital, Kuwait city, Kuwait, ⁵Rheumatology, Mubarak Al-Kabeer Hospital, Hawally, Kuwait, ⁶Rheumatology, Jahra Hospital, Jahra, Kuwait, ⁷Department of Mathematics, Kuwait Technical College, Kuwait city, Kuwait
Background/Purpose: An association between obesity and RA activity has been proposed in the literature. Kuwait has the highest obesity rate in The Middle East and…
Abstract Number: 2139 • 2016 ACR/ARHP Annual Meeting
High Fat Diet Induced Longitudinal Metabolic Changes Contribute to Acceleration of Osteoarthritis in Mice
Poulami Datta¹, Yue Zhang^2,3, Alexa Parousis¹, Anirudh Sharma¹, Evgeny Rossomacha¹, Rajiv Gandhi¹, Jason Rockel¹ and Mohit Kapoor¹, ¹Toronto Western Research Institute, University Health Network, Toronto, ON, Canada, ²Toronto Western Hospital, Arthritis Program, University Health Network, Toronto, ON, Canada, ³The first clinical college, Harbin Medical University, Harbin, China
Background/Purpose: The contribution of metabolic changes induced by high fat diet (HFD) to OA is poorly understood. We sought to determine if diet regulates…
Abstract Number: 2289 • 2016 ACR/ARHP Annual Meeting
Obesity and Echocardiographic Changes in the Different Stages of Gout
Rada Gancheva¹, Atanas Kundurdjiev², Mariana Ivanova¹, Todor Kundurzhiev³ and Zlatimir Kolarov¹, ¹Medical Faculty, Medical University, University Hospital "St. Iv. Rilski", Clinic of Rheumatology, Sofia, Bulgaria, ²Medical Faculty, Medical University, University Hospital "St. Iv. Rilski", Clinic of Nephrology, Sofia, Bulgaria, ³Medical University, Faculty of Public Health, Sofia, Bulgaria
Background/Purpose: Studies on gout and its stages as a cardiovascular (CV) risk factor are few and with contradictory results. We compared echocardiographic parameters, known as…
Abstract Number: 39 • 2015 ACR/ARHP Annual Meeting
Baseline Obesity and Subsequent Weight Loss Are Independently Associated with Cardiovascular Mortality in Established Rheumatoid Arthritis
Bryant R. England¹, Joshua F. Baker², Harlan Sayles³, Kaleb Michaud^4,5, Liron Caplan⁶, Lisa A. Davis⁶, Grant W. Cannon⁷, Brian Sauer⁸, E. Blair Solow⁹, Andreas Reimold¹⁰, Gail S. Kerr¹¹, Pascale Schwab¹² and Ted R. Mikuls¹³, ¹Division of Rheumatology, Department of Internal Medicine, University of Nebraska Medical Center, Omaha, NE, ²Rheumatology, University of Pennsylvania, Philadelphia, PA, ³University of Nebraska Medical Center, Omaha, NE, ⁴Internal Medicine, Division of Rheumatology, University of Nebraska Medical Center, Omaha, NE, ⁵National Data Bank for Rheumatic Diseases, Wichita, KS, ⁶Div of Rheumatology, Univ of CO Denver School of Med, Aurora, CO, ⁷Division of Rheumatology, Salt Lake City VA Medical Center and University of Utah, Salt Lake City, UT, ⁸Salt Lake City VA Medical Center and University of Utah, Salt Lake City, UT, ⁹Rheumatology, UT Southwestern Medical Center, Dallas, TX, ¹⁰Rheumatology, VAMC, University of Texas Southwestern Medical Center, Dallas, TX, ¹¹VAMC, Georgetown University, Washington, DC, ¹²Div Arth & Rheum Dis, Oregon Health & Sci Univ OP09, Portland, OR, ¹³Medicine, University of Nebraska Medical Center, Omaha, NE
Background/Purpose: In the general population, higher body mass index (BMI) is associated with cardiovascular (CV) disease. However, an obesity paradox has been observed in rheumatoid…
Abstract Number: 234 • 2015 ACR/ARHP Annual Meeting
Weight Variables and Their Association with Serum Urate Concentrations and Hyperuricemia in Young Adults
Angelo L. Gaffo^1,2, David R. Jacobs Jr.³, Huifen Wang⁴ and Kenneth G. Saag⁵, ¹Rheumatology, Birmingham VA Medical Center, Birmingham, AL, ²Medicine, University of Alabama at Birmingham, Birmingham, AL, ³Epidemiology, University of Minnesota, Minneapolis, MN, ⁴Nutritional Epidemiology Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA, ⁵University of Alabama at Birmingham, Birmingham, AL
Background/Purpose: How body weight, anthropometric parameters, and their changes are associated with serum urate concentrations and hyperuricemia remains unclear. The CARDIA study has been following…
Abstract Number: 321 • 2015 ACR/ARHP Annual Meeting
Effects of Bariatric Surgery on Long-Term Quality of Life Outcomes for Obese Patients with Osteoarthritis
Ankita Satpute¹, Deepak L. Bhatt², Sangeeta Kashyap³, Philip Schauer⁴, Colin O'Rourke⁵, James Bena⁵ and M. Elaine Husni⁶, ¹Case Western Reserve University School of Medicine, Cleveland, OH, ²Brigham and Women’s Hospital Heart & Vascular Center, Boston, MA, ³Endocrinology, Diabetes and Metabolism, Cleveland Clinic Foundation, Cleveland, OH, ⁴General Surgery, Cleveland Clinic Foundation, Cleveland, OH, ⁵Department of Quantitative Health Sciences, Cleveland Clinic Foundation, Cleveland, OH, ⁶Rheumatology Dept A50, Cleveland Clinic Foundation, Cleveland, OH
Background/Purpose: Osteoarthritis (OA) remains a debilitating burden for patients and a challenge to their physicians, as there is no known cure. Obesity has been linked…

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