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Abstracts tagged "obesity"

  • Abstract Number: 1289 • ACR Convergence 2022

    Evaluating Peri–operative Preferences of Bariatric Surgeons in the Management of Immunosuppressive Therapy During Bariatric Surgery

    Suguni Aushadhi Loku Galappaththy1 and Nicole Fearing2, 1University of Missouri Kansas City, Kansas City, MO, 2HCA Menorah Medical Center, Overland Park, KS

    Background/Purpose: As the number of bariatric procedures increases, surgeons will encounter more patients on long-term immunosuppressive medications that may increase post-operative complications. Currently, there are…
  • Abstract Number: 1328 • ACR Convergence 2022

    CT Evaluation of Bone Fragility 2 Years After Bariatric Surgery in Patients with Obesity: An Observational Study

    Marine FAUNY1, Marion Halin2, Edem Allado2, Didier Quilliot2, Laurent Brunaud2, Eliane Albuisson2, Isabelle Chary-Valckenaere2 and Damien Loeuille2, 1Nancy University Hospital, Toul, France, 2Nancy University Hospital, Vandoeuvre, France

    Background/Purpose: The objectives were to evaluate bone fragility on computed tomography (CT) in patients with obesity before and 2 years after bariatric surgery and to…
  • Abstract Number: 1329 • ACR Convergence 2022

    Prevalence of Bone Fragility on DXA and CT in Patients with Obesity

    Marion Halin1, Edem Allado1, Didier Quilliot1, Eliane Albuisson1, Isabelle Chary-Valckenaere1, Damien Loeuille1, Laurent Brunaud1 and Marine FAUNY2, 1Nancy University Hospital, Vandoeuvre, France, 2Nancy University Hospital, Toul, France

    Background/Purpose: Primary objective was to evaluate bone fragility prevalence on dual X-ray absorptiometry (DXA) and on computed tomography (CT), in patients with severe obesity. Secondary…
  • Abstract Number: 1510 • ACR Convergence 2022

    Modifying Lifestyle Factors May Offer the Potential to Enhance the Outcome of Tumour Necrosis Factor Inhibitors in Axial Spondyloarthritis – Data from 14 European Countries

    Gareth Jones1, Ovidiu Rotariu1, Brigitte Michelsen2, Bente Glintborg3, Bjorn Gudbjornsson4, Arni Geirsson5, Heikki Relas6, Pia Isomäki7, Jakub Závada8, Karel Pavelka9, Ziga Rotar10, Matija Tomsic10, Michael Nissen11, Adrian Ciurea12, Catalin Codreanu13, Johan Karlsson Wallman14, Eirik Kristianslund15, Simon Rasmussen16, Lykke Ørnbjerg17, Maria José Santos18, Mikkel Østergaard19, Merete L Hetland20 and Gary Macfarlane1, 1University of Aberdeen, Aberdeen, Scotland, United Kingdom, 2Center for treatment of Rheumatic and Musculoskeletal Diseases (REMEDY), Diakonhjemmet Hospital, Oslo, Norway, Kristiansand, Norway, 3Rigshospitalet, Glostrup, Virum, Denmark, 4Centre for Rheumatology Research, University Hospital, Reykjavik, Iceland, 5Department of Rheumatology, Landspitali University Hospital, Reykjavik, Iceland, 6Rheumatology, Inflammation Center, Helsinki University Hospital and University of Helsinki, Helsinki, Finland, 7Centre for Rheumatology, Tampere University Hospital, Tampere, Finland, 8Institute of Rheumatology, Prague, Czech Republic, 9Institute of Rheumatology, Department of Rheumatology, 1st Faculty of Medicine, Charles University, Prague, Czech Republic, Praha, Czech Republic, 10University Medical Centre Ljubljana, Ljubljana, Slovenia, 11Hopitaux Universitaires de Genève, Geneva, Switzerland, 12University Hospital Zurich, Zürich, Switzerland, 13Center for Rheumatic Diseases, Bucharest, Romania, 14Lund University and Skane University Hospital, Hjarup, Sweden, 15Diakonhjemmet Hospital, Division of Rheumatology and Research, Oslo, Norway, 16Copenhagen Center for Arthritis Research (COPECARE), Center for Rheumatology and Spine Diseases, Centre for Head and Orthopaedics, Rigshospitalet, Glostrup, Denmark, 17Copenhagen Center for Arthritis Research, Glostrup, Denmark, 18Hospital Garcia de Orta, Almada, Charneca da Caparica, Portugal, 19Rigshospitalet, University of Copenhagen, Glostrup, Denmark, 20Rigshospitalet, Glostrup, Denmark

    Background/Purpose: In axial spondyloarthritis (axSpA) much attention has been focused on pharmacological management, including tumour necrosis factor inhibitors (TNFi), as a means to reducing inflammation,…
  • Abstract Number: 1633 • ACR Convergence 2022

    Genetic Risk, Adherence to a Healthy Lifestyle, and Incident Gout in US Women and Men

    Kehuan Lin1, Natalie McCormick1, Leo Lu2, amit johi3, Chio Yokose4 and Hyon Choi5, 1Massachusetts General Hospital, Boston, MA, 2Arthritis Research Canada, Vancouver, BC, Canada, 3Regeneron, Boston, MA, 4Massachusetts General Hospital, Waltham, MA, 5MASSACHUSETTS GENERAL HOSPITAL, Lexington, MA

    Background/Purpose: Lifestyle and genetic factors have been independently related to incident gout risk. However, it remains unknown whether the genetic risk of gout is affected…
  • Abstract Number: 0153 • ACR Convergence 2022

    Obesity Is Associated with Higher Odds of Malignancy Development Among Dermatomyositis Patients

    Astia Allenzara1, Nakisa Sadeghi1, Carolina Alvarez2, Steve Maczuga3, Matthew Helm3, Amanda Nelson2 and Galen Foulke1, 1University of North Carolina, Chapel Hill, NC, 2University of North Carolina at Chapel Hill, Chapel Hill, NC, 3Penn State Hershey Medical Center, Hershey, PA

    Background/Purpose: Dermatomyositis (DM) is an idiopathic inflammatory myopathy with an increased risk of mortality and morbidity from cancer. Across the general population, excess body weight…
  • Abstract Number: 2234 • ACR Convergence 2022

    Obesity, Adipokines, and Chronic and Persistent Pain in Rheumatoid Arthritis

    Joshua Baker1, Kristin Wipfler2, Marianna Olave3, Sofia Pedro4, Patricia Katz5 and Kaleb Michaud6, 1University of Pennsylvania, Philadelphia, PA, 2FORWARD, The National Databank for Rheumatic Diseases, Omaha, NE, 3Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA, 4Forward, The National Databank for Rheumatic Diseases, Wichita, KS, 5UCSF, San Rafael, CA, 6University of Nebraska Medical Center, Omaha, NE

    Background/Purpose: Obesity has been linked to chronic pain and pain sensitization in the general population and among patients with rheumatoid arthritis (RA). The mechanism by…
  • Abstract Number: 0291 • ACR Convergence 2022

    Tofacitinib Leads to Significant Weight Gain – A Real Life Experience of 429 Patients

    Naga Prabu1, velammal petchaippan2, Gayathri anand3, Aswathi kumar1 and Saranya Ramachandiran3, 1SAKTHI RHEUMATOLOGY CENTRE PVT LTD, Coimbatore, India, 2PSG INSTTUTE OF MEDICAL SCIENCES AND RESEARCH, Coimbatore, India, 3sakthi rheumatology centre pvt l;td, Coimbatore, India

    Background/Purpose: Tofacitinib(Tofa) an oral Janus kinase inhibitor(JAK) has shown good promise in the management of rheumatoid arthritis and psoriatic arthritis. While being increasingly used in…
  • Abstract Number: 0405 • ACR Convergence 2022

    Efficacy and Safety of Tofacitinib in Patients with Ankylosing Spondylitis by Baseline BMI: A Post Hoc Analysis of Phase 2 and Phase 3 Trials

    Hillary Norton1, Paula Sliwinska-Stanczyk2, Tomas Hala3, Bassel Elzorkany4, Lori Stockert5, Harry Shi5, Cunshan Wang6, Jerome Paulissen7 and Christopher Ritchlin8, 1Sante Fe Rheumatology, Santa Fe, NM, 2Reumatika Centrum Reumatologii, Warsaw, Poland, 3Center for Clinical and Basic Research, Pardubice, Czech Republic, 4Department of Rheumatology, Cairo University, Cairo, Egypt, 5Pfizer, Inc, Collegeville, PA, 6Pfizer Inc, Groton, CT, 7Pfizer Inc, New York, NY, 8Allergy, Immunology and Rheumatology Division, University of Rochester Medical School, Canandaigua, NY

    Background/Purpose: Higher BMI is associated with reduced response to TNF inhibitors (TNFi) in patients (pts) with AS.1 Tofacitinib is an oral Janus kinase inhibitor for…
  • Abstract Number: 0680 • ACR Convergence 2022

    Association of Environmental Risk Factors with Antiphospholipid Antibodies and Thrombosis in 1199 International Patients Referred for Suspected Antiphospholipid Syndrome

    Medha Barbhaiya1, Deanna Jannat-Khah, DrPH, MSPH1, Jonah Levine1, Karen Costenbader2 and Doruk Erkan1, 1Hospital for Special Surgery, New York, NY, 2Brigham and Women's Hospital, Boston, MA

    Background/Purpose: Whether environmental risk factors induce antiphospholipid antibody (aPL) positivity and increase the risk of arterial thrombosis (AT) and venous thromboembolism (VTE) in aPL-positive patients…
  • Abstract Number: 0706 • ACR Convergence 2022

    Association Between Metabolic Syndrome and Knee Pain over 10-13 Years in Middle-Aged Adults

    Ambrish Singh, Brooklyn Fraser, Alison Venn, Leigh Blizzard, Changhai Ding and Benny Samuel Antony, Menzies Institute for Medical Research, University of Tasmania, Hobart, Australia

    Background/Purpose: Metabolic syndrome (MetS) is characterised by the clustering of central obesity with metabolic abnormalities. MetS has been suggested as having a role in osteoarthritis…
  • Abstract Number: 0741 • ACR Convergence 2022

    Prescribing Patterns of SGLT2 Inhibitors for Patients with Autoimmune Rheumatic Disease

    Emily G Oakes1, Jack Ellrodt1, May Choi2, Hongshu Guan1 and Karen Costenbader1, 1Brigham and Women's Hospital, Boston, MA, 2Brigham and Women's Hospital | University of Calgary, Calgary, AB, Canada

    Background/Purpose: Sodium-glucose co-transporter 2 inhibitors (SGLT2i, dapagliflozin, canagliflozin, and empagliflozin) are a class of oral hypoglycemic medication for management of Type II diabetes mellitus (T2D),…
  • Abstract Number: 0821 • ACR Convergence 2022

    Imiquimod Exaggerates Obesity-associated Adipose Tissue Inflammation in Murine Psoriasis Model

    Hee Joo Kim1, Dong Il Jeong2 and YunJae Jung3, 1Department of Dermatology, Gachon Gil Medical Center, Gachon University College of Medicine, Incheon, Republic of Korea, 2Department of Dermatology, Gachon University Gil Medical Center, Incheon, Republic of Korea, 3Department of Microbiology, Gachon University College of Medicine, Incheon, Republic of Korea

    Background/Purpose: Recently, obesity has been known to be associated with psoriasis: obesity has negative effects on the prevalence, severity, and treatment response of psoriasis. High…
  • Abstract Number: 0844 • ACR Convergence 2022

    Differences in Skin Advanced Glycation End-Products Levels Between Subgroups of Achilles Tendinopathy

    Hayley Powell Smitheman, Shawn L. Hanlon and Karin Grävare Silbernagel, University of Delaware, Newark, DE

    Background/Purpose: Achilles tendinopathy is a painful debilitating injury that negatively affects physical activity, quality of life, and overall health. While exercise is considered the gold…
  • Abstract Number: 0889 • ACR Convergence 2022

    Serum Adipokines Predict Incident Osteoporotic Fracture in Patients with Rheumatoid Arthritis

    Joshua Baker1, Katherine Wysham2, Bryant England3, Punyasha Roul4, Aleksander Lenert5, Grant Cannon6, Brian Sauer7, Geoffrey Thiele3 and Ted Mikuls8, 1University of Pennsylvania, Philadelphia, PA, 2VA Puget Sound/University of Washington, Seattle, WA, 3University of Nebraska Medical Center, Omaha, NE, 4UNMC, Omaha, NE, 5University of Iowa, Iowa City, IA, 6Retired, Salt Lake City, UT, 7Salt Lake City VA/University of Utah, Salt Lake City, UT, 8Division of Rheumatology, University of Nebraska Medical Center, Omaha, NE

    Background/Purpose: Adipokines are fat and muscle-secreted protein hormones that regulate metabolism. Adiponectin has been associated with fracture in the general population while the role of…
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