Abstracts tagged "obesity"

Abstract Number: 105 • 2020 Pediatric Rheumatology Symposium
Discovering the Implications of Adiposity in Juvenile Dermatomyositis
Vy Do¹, Chanhee Jo ², Jaclyn Albin ¹, Tracey Wright ¹, Julie Fuller ³ and Una Makris ¹, ¹UT Southwestern Medical Center, Dallas, ²Texas Scottish Rite Hospital, Dallas, ³UT Southwestern Medical Center, Frisco
Background/Purpose: Obesity and pro-inflammatory cytokines produced by adipocytes have been linked to many outcomes including disease severity, treatment response, and disease progression in several autoimmune…
Abstract Number: 2077 • 2019 ACR/ARP Annual Meeting
Population Impact Attributable to Modifiable Risk Factors for Hyperuricemia and the Fallacy of the Variance Explained
Natalie McCormick ¹, Na Lu ², Sharan Rai ³, Chio Yokose ⁴, Yuqing Zhang ⁴ and Hyon K. Choi⁴, ¹Massachusetts General Hospital and Harvard Medical School, Boston, MA, ²Massachusetts General Hosptial, Boston, MA, ³Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA, ⁴Massachusetts General Hospital, Boston, MA
Background/Purpose: In a seminal BMJ paper (Prior 1986), the Tokelau Island migrant study for gout and hyperuricemia concluded preventive strategies to modify body mass, diet…
Abstract Number: 2194 • 2019 ACR/ARP Annual Meeting
Surgical and Medical Weight Loss Threshold Dictates Decreases in Knee Osteoarthritis Pain but Not Reductions in Inflammatory Biomarkers
Fernando Bomfim¹, Shannon Chen ¹, Stephen Zak ², Taylor Jazrawi ¹, Madeline Kundler ², Vivienne Qie ², Laura Peralta ², Jose Aleman ², Christine Ren-Fielding ², Holly Lofton ², Jyoti Patel ², Mukundan Attur ³, Steven B. Abramson ³ and Jonathan Samuels ¹, ¹NYU Langone Health, New York, ²NYU Langone Health, New York, NY, ³NYU School of Medicine and NYU Langone Orthopedic Hospital, New York City, NY
Background/Purpose: Weight loss in obese patients can reduce knee osteoarthritis (OA) pain, even when physical therapy and intra-articular injections have failed. The impacts of either…
Abstract Number: 2376 • 2019 ACR/ARP Annual Meeting
Modifiable Factors Associated with Response to Treatment in Early Rheumatoid Arthritis
Zoe Brown ¹, Robert Metcalf ², Jana Bednarz ³, Christiana Stavrou ⁴, Llewellyn Spargo ², Michael James ² and Susanna Proudman⁵, ¹The University of Melbourne, Melbourne, Victoria, Australia, ²Rheumatology Unit, The Royal Adelaide Hospital, Adelaide, South Australia, Australia, ³Adelaide Health Technology Assessment, The University of Adelaide, Adelaide, South Australia, Australia, ⁴University College London Hospital, London, United Kingdom, ⁵University of Adelaide, Adelaide, Australia
Background/Purpose: Among the potentially modifiable prognostic factors in RA, there is evidence for associations with smoking history, BMI and dietary fish oil supplementation. An integrated…
Abstract Number: 2459 • 2019 ACR/ARP Annual Meeting
Effect of Obesity and Surgical Weight Loss on Joint Surgery Hospitalizations in Psoriatic Arthritis: Data from National Inpatient Sample
Rashmi Dhital¹, Dilli Ram Poudel ², Anthony Donato ³, Olubunmi Oladunjoye ⁴ and Paras Karmacharya ⁵, ¹Reading Hospital ,PA, Shillington, PA, ²University of Pennsylvania, Philadelphia, ³Reading Hospital, PA, Reading, ⁴Reading Hospital, PA, West Reading, PA, ⁵Reading Hospital, Mayo Clinic, Rochester
Background/Purpose: Obesity is associated with higher disease activity and poor treatment response in patients with psoriatic arthritis (PsA). However, there is limited data as to…
Abstract Number: 199 • 2019 ACR/ARP Annual Meeting
Obesity and Incident Opioid Use in Rheumatoid Arthritis
Joshua Baker¹, Sofia Pedro ² and Kaleb Michaud ³, ¹University of Pennsylvania, Philadelphia, PA, ²Forward, The National Databank for Rheumatic Diseases, Wichita, KS, ³University of Nebraska Medical Center, Omaha, NE
Background/Purpose: Prevalent chronic use of opioids approximately 17% among patients with rheumatoid arthritis (RA) and has increased over the last decade.(1) Obesity may be a…
Abstract Number: 284 • 2019 ACR/ARP Annual Meeting
Impact of Body Mass Index on the Agreement Between Ultrasound- and Clinical Assessments of Disease Activity in Rheumatoid Arthritis : Multicenter and Cross-sectional Study
Gaël Mouterde¹, Federico Manna ², Benoît Le Goff ³, Jean-David Albert ⁴, Sandrine Jousse-Joulin ⁵, Frédérique Gandjbakhch ⁶, Damien Loeuille ⁷, Philippe Gaudin ⁸, Muriel Piperno ⁹, Frédéric Banal ¹⁰, Bénédicte Jamard ¹¹, Carine Salliot ¹², Nicolas Molinari ², Bernard Combe ¹³, Maria-Antonietta D'Agostino ¹⁴ and Cédric Lukas ¹⁵, ¹CHU Montpellier and Univ Montpellier, Montpellier, France, ²Clinical Research and Epidemiology Unit, University Hospital, Montpellier, France, ³Rheumatology Department, CHU de Nantes and INSERM UMR 1238, Faculty of Biology of Nantes, Nantes, France, ⁴Rheumatology department, Rennes University Hospital and Institut NUMECAN, INSERM U 1241, Rennes, Bretagne, France, ⁵Rheumatology Department, Cavale Blanche Hospital and Brest Occidentale University, Brest, France, ⁶Rheumatology department, Pitié Salpêtrière hospital, APHP and Sorbonne University, Paris, France, ⁷Rheumatology, Nancy University Hospital and and UMR 7365 CNRS-UL IMoPA, Université de Lorraine, VANDOEUVRE, France, ⁸Rheumatology Department, CHU Grenoble Alpes Hôpital Sud and GREPI - Université Grenoble Alpes, EA7408, Grenoble - Echirolles, France, ⁹Rheumatology Department, Hospices Civils de Lyon, centre hospitalier Lyon Sud, Pierre Bénite, France, ¹⁰Service rhumatologie, hôpital d'instruction des armées Bégin, Saint Mandé, France, ¹¹Department of Rheumatology, Purpan Teaching Hospital, Toulouse, France, ¹²Rheumatology Unit, centre hospitalier regional d'Orleans, Orléans, France, ¹³CHU Montpellier, Montpellier University, Montpellier, France, ¹⁴UMR1173, INSERM/Versailles-Saint Quentin University, France Ambroise Paré Hospital (AP-HP) Department of Rheumatology, Boulogne Billancourt, France, ¹⁵Rheumatology department, CHU Montpellier, Univ Montpellier, Montpellier, France
Background/Purpose: Clinical evaluation of synovitis in rheumatoid arthritis (RA) is difficult in obese (O) and overweight patients, due to the fat pad located around the…
Abstract Number: 56 • 2018 ACR/ARHP Annual Meeting
Comparison of Metabolic Changes in Osteoarthritis and Rheumatoid Arthritis Mouse Models
Marie-Lisa Hülser¹, Hani Manfred Sauermilch¹, Carina Schreiyäck¹, Yubin Luo², Aline Bozec², Georg Schett³, Ulf Müller-Ladner⁴ and Elena Neumann¹, ¹Dept. of Rheumatology and Clinical Immunology, Campus Kerckhoff, Justus-Liebig-University Gießen, Germany, Bad Nauheim, Germany, ²University of Erlangen-Nürnberg, Department Clinic of Medicine 3 - Immunology and Rheumatology, Erlangen, Germany, Erlangen, Germany, ³Friedrich-Alexander-Universität Erlangen, Nürnberg und Universitätsklinikum Erlangen, Erlangen, Germany, ⁴Dept. of Rheumatology and Clinical Immunology, Campus Kerckhoff, Justus-Liebig-University Giessen, Germany, Bad Nauheim, Germany
Background/Purpose: Adipocytokines are bioactive factors produced mainly by adipose tissue. They not only regulate energy homeostasis, but also influence immune responses. Osteoarthritis (OA) is one…
Abstract Number: 434 • 2018 ACR/ARHP Annual Meeting
Trends in Procedure Type, Patient Characteristics, and Outcomes Among Persons with Knee Osteoarthritis Undergoing Bariatric Surgery, 2005-2014
Yusi Gong¹, Faith Selzer², Bhushan Deshpande^1,3 and Elena Losina^1,4,5, ¹Orthopaedic and Arthritis Center for Outcomes Research, Department of Orthopedic Surgery, Brigham & Women's Hospital, Boston, MA, ²Orthopedic Surgery, Orthopedic and Arthritis Center for Outcomes Research, Brigham and Women's Hospital, Boston, MA, ³Harvard Medical School, Boston, MA, ⁴Orthopaedic Surgery, Harvard Medical School, Boston, MA, ⁵BU School of Public Health, Boston, MA
Background/Purpose: Bariatric surgery, the most effective treatment for losing weight and maintaining weight loss among morbidly obese persons, has been evolving as a treatment for…
Abstract Number: 1514 • 2018 ACR/ARHP Annual Meeting
Impact of Comorbidity Burden and Obesity on the Effectiveness of Tocilizumab in Patients with Rheumatoid Arthritis
Dimitrios A. Pappas¹, Carol J. Etzel², Margaux Crabtree³, Jennie H. Best⁴, Steve Zlotnick⁴ and Joel Kremer⁵, ¹Columbia University, New York, NY, ²Corrona LLC, Waltham, MA, ³Corrona, LLC, Waltham, MA, ⁴Genentech, Inc., South San Francisco, CA, ⁵Albany Medical College and The Center for Rheumatology, Albany, NY
Background/Purpose: Few real-world studies have evaluated the impact of comorbidity burden or obesity on the effectiveness of tocilizumab (TCZ) for the improvement of rheumatoid arthritis…
Abstract Number: 1518 • 2018 ACR/ARHP Annual Meeting
Baricitinib and Tofacitinib in Real Life – Does Obesity Impact Response to Janus Kinase Inhibitor Therapy in Rheumatoid Arthritis?
Yvette Meißner¹, Lisa Baganz¹, Matthias Schneider², Ilka Schwarze³, Martin Feuchtenberger⁴, Angela Zink⁵ and Anja Strangfeld⁶, ¹Programme Area Epidemiology, German Rheumatism Research Center, Berlin, Germany, ²Policlinic for Rheumatology & Hiller Research Centre for Rheumatology, Department of Rheumatology & Hiller Research Unit, Medical Faculty, University Hospital, Heinrich-Heine-University Duesseldorf, Duesseldorf, Germany, ³Praxis internistische Rheumatologie, Leipzig, Germany, ⁴Rheumatologie/Klinische Immunologie, Kreiskliniken Altötting-Burghausen, Burghausen, Germany, ⁵Epidemiology Unit / Rheumatology and Clinical Immunology, German Rheumatism Research Centre (DRFZ) / Charité University Hospital, Berlin, Germany, ⁶Epidemiology, German Rheumatism Research Center, Berlin, Germany
Background/Purpose: The influence of obesity on treatment response of tumor necrosis factor inhibitors in patients with rheumatoid arthritis (RA) is described in literature, but data…
Abstract Number: 1547 • 2018 ACR/ARHP Annual Meeting
Impact of Obesity on Drug Survival of Tofacitinib in Patients with Rheumatoid Arthritis: Analysis from the Turkbio Registry
Hakan Babaoglu¹, Berna Goker¹, Nevsun İnanç², Merih Birlik³, Suleyman Serdar Koca⁴, Ayse Cefle⁵, Ediz Dalkiliç⁶, Abdurrahman Tufan¹, Sema Yilmaz⁷, Soner Senel⁸, Servet Akar⁹, Nurullah Akkoc¹⁰, Fatos Onen³ and Ummugulsum Gazel¹¹, ¹Internal Medicine-Rheumatology, Gazi University Faculty of Medicine, Ankara, Turkey, ²Rheumatology, Marmara University faculty of Medicine, İstanbul, Turkey, ³Rheumatology, Dokuz Eylul University Faculty of Medicine, İzmir, Turkey, ⁴Rheumatology, Firat University Faculty of Medicine, Elazığ, Turkey, ⁵Rheumatology, Kocaeli University, Faculty of Medicine, Kocaeli, Turkey, ⁶Department of Internal Medicine, Division of Rheumatology, Uludağ University Faculty of Medicine, Bursa, Turkey, ⁷Department of Rheumatology, Selcuk University School of Medicine, Konya, Turkey, ⁸Rheumatology, Kayseri Erciyes University, Faculty of Medicine, Kayseri, Turkey, ⁹Department of Internal Medicine, Division of Rheumatology,, Izmir Katip Çelebi University Faculty of Medicine, Izmir, Turkey, ¹⁰Rheumatology, İzmir, Turkey, İzmir, Turkey, ¹¹Rheumatology, Marmara University faculty of Medicine, Istanbul, Turkey
Background/Purpose: Several previous reports suggest that obesity impairs the effectiveness and drug survival of anti-TNF-α agents in rheumatoid arthritis (RA). The aim of the study…
Abstract Number: 1908 • 2018 ACR/ARHP Annual Meeting
Bariatric Surgery Does Not Affect the Incidence of Rheumatoid Arthritis in Obese Subjects
Yuan Zhang¹, Cristina Maglio², Anna Rudin³ and Lena Carlsson⁴, ¹Dep. of Rheumatology and Inflammation Research, The Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden, ²Dep. of Rheumatology and Inflammation Research and Wallenberg Centre for Molecular and Translational Medicine, The Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden, ³Dept of Rheumatology and Inflammation Research, The Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden, ⁴Department of Molecular and Clinical Medicine, The Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden
Background/Purpose: Obesity is among the risk factors for rheumatoid arthritis (RA). Bariatric surgery is an effective treatment to achieve weight loss and to prevent obesity-related…
Abstract Number: 2331 • 2018 ACR/ARHP Annual Meeting
Obesity Might Positively Affect TNF Mediated Bone Metabolism in RA Patients
Mie Jin Lim¹, Won Park², Seong Ryul Kwon³, Kyong-Hee Jung⁴ and Seung Yun Lee³, ¹Division of Rheumatology, Departments of Internal Medicine, Inha University Hospital, Incheon, Korea, Republic of (South), ²Medicine/Rheumatology, Inha University Hospital, Incheon, Korea, Republic of (South), ³Division of Rheumatology, Department of Internal Medicine, Inha University Hospital, Incheon, Korea, Republic of (South), ⁴Rheumatology, Inha University Hospital, Incheon, Korea, Republic of (South)
Background/Purpose: In this study, we tried to find out the effect of obesity on bone metabolism after one year of anti-TNF agent use. Methods: Thirty-two…
Abstract Number: 2984 • 2018 ACR/ARHP Annual Meeting
Lifestyle and MTX Use Are the Strongest Predictors of Not Achieving Remission in the First Year of Rheumatoid Arthritis: Results from the Canadian Early Arthritis Cohort (CATCH)
Susan J. Bartlett^1,2, Orit Schieir³, Marie-France Valois⁴, Carol Hitchon⁵, Louis Bessette⁶, Gilles Boire⁷, Carter Thorne⁸, Janet E. Pope⁹, Vivian P. Bykerk¹⁰, Edward C. Keystone¹¹, Diane Tin¹² and Glen Hazlewood¹³, ¹Department of Medicine, Division of ClinEpi, Rheumatology, Respirology, McGill University, Montreal, QC, Canada, ²Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, ³McGill University, Montreal, ON, Canada, ⁴McGill University, Montreal, QC, Canada, ⁵University of Manitoba, Winnipeg, MB, Canada, ⁶Division of Rheumatology, Department of Medicine, CHU de Québec-Université Laval, Québec, QC, Canada, ⁷Rheumatology Division, Centre intégré universitaire de santé et de services sociaux de l'Estrie - Centre Hospitalier Universitaire de Sherbrooke and Universite de Sherbrooke, Sherbrooke, QC, Canada, ⁸University of Toronto, Newmarket, ON, Canada, ⁹Department of Medicine, University of Western Ontario, London, ON, Canada, ¹⁰Hospital for Special Surgery, New York, NY, ¹¹Mount Sinai Hospital, Toronto, ON, Canada, ¹²The Arthritis Program, Southlake Regional Health Centre, Newmarket, ON, Canada, ¹³Departments of Medicine and Community Health Sciences, University of Calgary, Calgary, AB, Canada
Background/Purpose: Implementation of RA guidelines have improved remission outcomes in RA; nevertheless 45% of early RA participants do not achieve remission in the first year.…

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