Abstracts tagged "obesity"

Abstract Number: 2352 • 2016 ACR/ARHP Annual Meeting
Obesity-Related Systemic Inflammation and Knee Synovitis
Devyani Misra¹, Tuhina Neogi², Michael C. Nevitt³, James Torner⁴, Cora E. Lewis⁵ and David T. Felson⁶, ¹Medicine, Section of, BUSM, Boston, MA, ²Clinical Epidemiology, BUSM, Boston, MA, ³Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, ⁴University of Iowa, UIowa, Iowa City, IA, ⁵University of Alabama Birmingham, Birmingham, AL, ⁶Clinical Epidemiology Unit, Boston University School of Medicine, Boston, MA
Background/Purpose: Obesity, a major risk factor for knee osteoarthritis (OA), is a state of systemic inflammation through elaboration of adipokines (pro and anti-inflammatory cytokines) from…
Abstract Number: 2369 • 2016 ACR/ARHP Annual Meeting
Obesity and Severity of Joint Space Narrowing Are Associated with Viscosupplementation Failure in Patients with Knee Osteoarthritis. Post-Hoc Analysis of a Double-Blind, Controlled, Multicentre, Randomized Trial
Florent Eymard¹, Xavier Chevalier² and Thierry Conrozier³, ¹Department of Rheumatology, APHP Henri Mondor Hospital, Paris, France, ²Rheumatology, Hopital Henri Mondor, Créteil, France, ³Department of Rheumatology,, Nord Franche-Comté Hospital, Belfort, France
Background/Purpose: Viscosupplementation (VS) is still controversial. One of the key points is the lack of well-identified factors of response. We aimed to identify clinical…
Abstract Number: 2996 • 2016 ACR/ARHP Annual Meeting
High Fat Diet-Induced Osteoarthritis Progression Is Dependent on Toll-like Receptor 4
Mary Beth Humphrey¹, Evangelia Kalaitzoglou², Camille Herron², Yanqing HU², Yao Fu³, Erika Barboza Prado Lopes³, Elise Donovan³, Joanna Hudson³ and Timothy Griffin³, ¹Medicine/Rheumatology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, ²Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK, ³Aging and Metabolism, Oklahoma Medical Research Foundation, Oklahoma City, OK
Background/Purpose: Obesity is considered the primary preventable risk factor for OA, increasing the risk of developing OA in weight-bearing joints, especially the knee, as…
Abstract Number: 3069 • 2016 ACR/ARHP Annual Meeting
Weight Loss in the Early Rheumatoid Arthritis Period Is Associated with Subsequent Increased Mortality in RA Patients and Matched Comparators: Evidence Against an RA-Specific Obesity Paradox
Jeffrey A. Sparks¹, Shun-Chiao Chang², Uyen Sa D.T. Nguyen^3,4, Medha Barbhaiya², Sara K. Tedeschi², Bing Lu², Karen H. Costenbader², Yuqing Zhang⁵, Hyon K. Choi⁶ and Elizabeth W. Karlson², ¹Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, ²Rheumatology, Immunology and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, ³Orthopedics and Physical Rehabilitation, University of Massachusetts Medical School, Worcester, MA, ⁴Boston University School of Medicine, Boston, MA, ⁵Clinical Epidemiology and Training Unit, Boston University School of Medicine, Boston, MA, ⁶Rheumatology, Allergy and Immunology, Massachusetts General Hospital and Harvard Medical School, Boston, MA
Background/Purpose : Weight loss may explain the obesity paradox for mortality, since those who unintentionally lose weight to reach normal BMI may have higher mortality…
Abstract Number: 3087 • 2016 ACR/ARHP Annual Meeting
Association of Weight Loss with Improved Disease Activity in Patients with Rheumatoid Arthritis
David J. Kreps^1,2, Florencia Halperin³, Sonali P. Desai³, Zhi Zhang³, Elena Losina³, Elizabeth W. Karlson¹, Bonnie L. Bermas¹ and Jeffrey A. Sparks⁴, ¹Rheumatology, Immunology and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, ²Boston University, Boston, MA, ³Division of Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, ⁴Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA
Background/Purpose : Obesity has been associated with worsened RA outcomes and increased disease activity. However, few longitudinal studies have investigated whether weight loss might improve…
Abstract Number: 3193 • 2016 ACR/ARHP Annual Meeting
Is an Intensive Diet and Exercise Regimen Cost-Effective for Obese and Overweight Patients with Symptomatic Knee OA?
Elena Losina¹, Karen C. Smith², A. David Paltiel³, Lisa Gale Suter⁴, Jeffrey N. Katz⁵ and Stephen P. Messier⁶, ¹Orthopedics, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, ²Orthopaedics, Brigham and Women's Hospital, Boston, MA, ³Yale University, New Haven, CT, ⁴Medicine, Rheumatology, Yale University, New Haven, CT, ⁵Orthopaedics, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, ⁶Department of Health and Exerc, Wake Forest University, Winston-Salem, NC
Background/Purpose: About 50% of persons with knee OA are obese. Quality-adjusted life-year losses due to knee OA and obesity exceed 3.5 per person. The results…
Abstract Number: 397 • 2016 ACR/ARHP Annual Meeting
Comorbidities Associated with Pediatric Psoriatic Arthritis
Cynthia Manos¹, Rui Xiao², Alexis Ogdie³, Timothy Brandon⁴ and Pamela F. Weiss^5,6, ¹Rheumatology, Children's Hospital of Philadelphia, Philadelphia, PA, ²Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, PA, ³University of Pennsylvania, Philadelphia, PA, ⁴Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA, ⁵Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, ⁶Division of Rheumatology, Center for Pediatric Clincial Effectiveness, Children's Hospital of Philadelphia, Philadelphia, PA
Background/Purpose: In adults, psoriatic arthritis (PsA) is associated with an increased prevalence of obesity, hypertension, and diabetes. It is not yet known if pediatric patients…
Abstract Number: 39 • 2015 ACR/ARHP Annual Meeting
Baseline Obesity and Subsequent Weight Loss Are Independently Associated with Cardiovascular Mortality in Established Rheumatoid Arthritis
Bryant R. England¹, Joshua F. Baker², Harlan Sayles³, Kaleb Michaud^4,5, Liron Caplan⁶, Lisa A. Davis⁶, Grant W. Cannon⁷, Brian Sauer⁸, E. Blair Solow⁹, Andreas Reimold¹⁰, Gail S. Kerr¹¹, Pascale Schwab¹² and Ted R. Mikuls¹³, ¹Division of Rheumatology, Department of Internal Medicine, University of Nebraska Medical Center, Omaha, NE, ²Rheumatology, University of Pennsylvania, Philadelphia, PA, ³University of Nebraska Medical Center, Omaha, NE, ⁴Internal Medicine, Division of Rheumatology, University of Nebraska Medical Center, Omaha, NE, ⁵National Data Bank for Rheumatic Diseases, Wichita, KS, ⁶Div of Rheumatology, Univ of CO Denver School of Med, Aurora, CO, ⁷Division of Rheumatology, Salt Lake City VA Medical Center and University of Utah, Salt Lake City, UT, ⁸Salt Lake City VA Medical Center and University of Utah, Salt Lake City, UT, ⁹Rheumatology, UT Southwestern Medical Center, Dallas, TX, ¹⁰Rheumatology, VAMC, University of Texas Southwestern Medical Center, Dallas, TX, ¹¹VAMC, Georgetown University, Washington, DC, ¹²Div Arth & Rheum Dis, Oregon Health & Sci Univ OP09, Portland, OR, ¹³Medicine, University of Nebraska Medical Center, Omaha, NE
Background/Purpose: In the general population, higher body mass index (BMI) is associated with cardiovascular (CV) disease. However, an obesity paradox has been observed in rheumatoid…
Abstract Number: 234 • 2015 ACR/ARHP Annual Meeting
Weight Variables and Their Association with Serum Urate Concentrations and Hyperuricemia in Young Adults
Angelo L. Gaffo^1,2, David R. Jacobs Jr.³, Huifen Wang⁴ and Kenneth G. Saag⁵, ¹Rheumatology, Birmingham VA Medical Center, Birmingham, AL, ²Medicine, University of Alabama at Birmingham, Birmingham, AL, ³Epidemiology, University of Minnesota, Minneapolis, MN, ⁴Nutritional Epidemiology Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA, ⁵University of Alabama at Birmingham, Birmingham, AL
Background/Purpose: How body weight, anthropometric parameters, and their changes are associated with serum urate concentrations and hyperuricemia remains unclear. The CARDIA study has been following…
Abstract Number: 321 • 2015 ACR/ARHP Annual Meeting
Effects of Bariatric Surgery on Long-Term Quality of Life Outcomes for Obese Patients with Osteoarthritis
Ankita Satpute¹, Deepak L. Bhatt², Sangeeta Kashyap³, Philip Schauer⁴, Colin O'Rourke⁵, James Bena⁵ and M. Elaine Husni⁶, ¹Case Western Reserve University School of Medicine, Cleveland, OH, ²Brigham and Women’s Hospital Heart & Vascular Center, Boston, MA, ³Endocrinology, Diabetes and Metabolism, Cleveland Clinic Foundation, Cleveland, OH, ⁴General Surgery, Cleveland Clinic Foundation, Cleveland, OH, ⁵Department of Quantitative Health Sciences, Cleveland Clinic Foundation, Cleveland, OH, ⁶Rheumatology Dept A50, Cleveland Clinic Foundation, Cleveland, OH
Background/Purpose: Osteoarthritis (OA) remains a debilitating burden for patients and a challenge to their physicians, as there is no known cure. Obesity has been linked…
Abstract Number: 331 • 2015 ACR/ARHP Annual Meeting
Are Metabolic Factors Associated with Shoulder Osteoarthritis? a Multicentric Study.
Pierre-Antoine Juge¹, Laure Bérard², Salma Kotti³, Tabassome Simon⁴, Francis Berenbaum⁵, Geoffroy Nourissat⁶ and Jérémie Sellam⁷, ¹Rheumatology Department, Saint-Antoine Hospital, Paris, France, ²Rheumatology Department, Le Havre Hospital, Le Havre, France, ³Unité de Recherche Clinique de l’Est Parisien, Saint-Antoine Hospital, Paris, France, ⁴Unité de Recherche Clinique de l'Est Parisien URCEST, Saint-Antoine Hospital, AP-HP, Univ Paris 06, Paris, France, ⁵Rheumatology, Inserm UMRS_938, AP-HP, St Antoine Hospital, Univ Paris 06, DHU i2B, Paris, France, ⁶Orthopedic surgery, Clinique des Maussins & St-Antoine Hospital AP-HP, Paris, France, ⁷Rheumatology and Inserm UMRS_938, AP-HP, St Antoine Hospital, Univ Paris 06, DHU i2B, Paris, France
Background/Purpose: Aging, trauma and obesity are the 3 main risk factors for knee, hip and hand osteoarthritis (OA). It is noteworthy that risk factors for…
Abstract Number: 688 • 2015 ACR/ARHP Annual Meeting
Clinical Improvements in Psoriasis and Psoriatic Arthritis with Surgical Weight Loss
Monica Sethi¹, Christine Ren-Fielding², Ana Clara Caminer^3,4, Jose U. Scher⁵ and Soumya M. Reddy⁶, ¹Department of Surgery, Division of Bariatric Surgery, New York University School of Medicine, New York, NY, ²Department of Surgery, New York University School of Medicine, New York, NY, ³Rheumatology, Facultad de Ciencias Médicas, Universidad Nacional de Rosario, Rosario, Argentina, ⁴Rheumatology, Sanatorio Parque, Rosario, Argentina, ⁵Department of Medicine, Division of Rheumatology, New York University School of Medicine, New York, NY, ⁶Division of Rheumatology, New York University School of Medicine, New York, NY
Background/Purpose: Obesity is more prevalent among patients with psoriasis and psoriatic arthritis (PsA). This correlation appears to be related to fat tissue-driven systemic inflammation. Although…
Abstract Number: 1586 • 2015 ACR/ARHP Annual Meeting
Weight Loss in Obese Rheumatoid Arthritis (RA) Patients Improves Disease Activity without Modifying RA Treatment
Elisa Gremese¹, Maria Rita Gigante¹, Barbara Tolusso¹, Anna Laura Fedele¹, Silvia Canestri¹, Barbara Aquilanti², Clara Di Mario¹, Luca Petricca¹, Stefano Alivernini¹ and Gianfranco Ferraccioli¹, ¹Division of Rheumatology, Institute of Rheumatology, Catholic University of the Sacred Heart, Rome, Italy, ²Dietology Service, Association Columbus, Catholic University of the Sacred Heart, Rome, Italy
Background/Purpose: Obesity is recognized as a systemic, low-grade inflammatory state and the adipose tissue as an endocrine organ releasing pro-inflammatory cytokines. On the other hand,…
Abstract Number: 1699 • 2015 ACR/ARHP Annual Meeting
Obesity and Pediatric Psoriatic Arthritis
Cynthia Manos¹, Timothy Brandon², Rui Xiao³, Jon M. Burnham⁴ and Pamela F. Weiss¹, ¹Rheumatology, Children's Hospital of Philadelphia, Philadelphia, PA, ²Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA, ³Department of Pediatrics, Division of Biostatistics, Children's Hospital of Philadelphia, Philadelphia, PA, ⁴Pediatric Rheumatology, Children's Hospital of Philadelphia, Philadelphia, PA
Background/Purpose: Studies in adults have shown a significant association between obesity and psoriatic arthritis. The association of obesity with pediatric psoriatic arthritis is unknown.…
Abstract Number: 2274 • 2015 ACR/ARHP Annual Meeting
Increasing Moderate-to-Vigorous Activity and Decreasing Sedentary Time Are Associated with 2-Year Weight Loss in Obese Persons with or at Risk for Knee Osteoarthritis
Christine Pellegrini¹, Jing Song², Rowland W. Chang³, Pamela Semanik⁴, Julia (Jungwha) Lee⁵, Linda S. Ehrlich-Jones⁶, Daniel Pinto⁷ and Dorothy D. Dunlop⁸, ¹Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, ²Institute for Healthcare Studies, Northwestern University, Chicago, IL, ³Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, ⁴College of Nursing, Rush University, Chicago, IL, ⁵Department of Preventive Medicine, Biostatistics Collaboration Center, Northwestern University Feinberg School of Medicine, Chicago, IL, ⁶Research CROR, Rehabilitation Institute Chicago, Chicago, IL, ⁷Department of Physical Therapy & Human Movement Sciences, Northwestern University, Chicago, IL, ⁸Institute for Healthcare Studies, Northwestern University Feinberg School of Medicine, Chicago, IL
Background/Purpose: Moderate-to-vigorous physical activity (MVPA) is recommended for weight loss; however it is unclear how activity or sedentary changes influence long-term weight loss in obese…

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Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. Academic institutions, private organizations and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part a scientific presentation or presentation of additional new information that will be available at the time of the meeting) is under embargo until Saturday, November 11, 2023.

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