Abstracts tagged "obesity"

Abstract Number: 2352 • 2016 ACR/ARHP Annual Meeting
Obesity-Related Systemic Inflammation and Knee Synovitis
Devyani Misra¹, Tuhina Neogi², Michael C. Nevitt³, James Torner⁴, Cora E. Lewis⁵ and David T. Felson⁶, ¹Medicine, Section of, BUSM, Boston, MA, ²Clinical Epidemiology, BUSM, Boston, MA, ³Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, ⁴University of Iowa, UIowa, Iowa City, IA, ⁵University of Alabama Birmingham, Birmingham, AL, ⁶Clinical Epidemiology Unit, Boston University School of Medicine, Boston, MA
Background/Purpose: Obesity, a major risk factor for knee osteoarthritis (OA), is a state of systemic inflammation through elaboration of adipokines (pro and anti-inflammatory cytokines) from…
Abstract Number: 2369 • 2016 ACR/ARHP Annual Meeting
Obesity and Severity of Joint Space Narrowing Are Associated with Viscosupplementation Failure in Patients with Knee Osteoarthritis. Post-Hoc Analysis of a Double-Blind, Controlled, Multicentre, Randomized Trial
Florent Eymard¹, Xavier Chevalier² and Thierry Conrozier³, ¹Department of Rheumatology, APHP Henri Mondor Hospital, Paris, France, ²Rheumatology, Hopital Henri Mondor, Créteil, France, ³Department of Rheumatology,, Nord Franche-Comté Hospital, Belfort, France
Background/Purpose: Viscosupplementation (VS) is still controversial. One of the key points is the lack of well-identified factors of response. We aimed to identify clinical…
Abstract Number: 2996 • 2016 ACR/ARHP Annual Meeting
High Fat Diet-Induced Osteoarthritis Progression Is Dependent on Toll-like Receptor 4
Mary Beth Humphrey¹, Evangelia Kalaitzoglou², Camille Herron², Yanqing HU², Yao Fu³, Erika Barboza Prado Lopes³, Elise Donovan³, Joanna Hudson³ and Timothy Griffin³, ¹Medicine/Rheumatology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, ²Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK, ³Aging and Metabolism, Oklahoma Medical Research Foundation, Oklahoma City, OK
Background/Purpose: Obesity is considered the primary preventable risk factor for OA, increasing the risk of developing OA in weight-bearing joints, especially the knee, as…
Abstract Number: 3069 • 2016 ACR/ARHP Annual Meeting
Weight Loss in the Early Rheumatoid Arthritis Period Is Associated with Subsequent Increased Mortality in RA Patients and Matched Comparators: Evidence Against an RA-Specific Obesity Paradox
Jeffrey A. Sparks¹, Shun-Chiao Chang², Uyen Sa D.T. Nguyen^3,4, Medha Barbhaiya², Sara K. Tedeschi², Bing Lu², Karen H. Costenbader², Yuqing Zhang⁵, Hyon K. Choi⁶ and Elizabeth W. Karlson², ¹Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, ²Rheumatology, Immunology and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, ³Orthopedics and Physical Rehabilitation, University of Massachusetts Medical School, Worcester, MA, ⁴Boston University School of Medicine, Boston, MA, ⁵Clinical Epidemiology and Training Unit, Boston University School of Medicine, Boston, MA, ⁶Rheumatology, Allergy and Immunology, Massachusetts General Hospital and Harvard Medical School, Boston, MA
Background/Purpose : Weight loss may explain the obesity paradox for mortality, since those who unintentionally lose weight to reach normal BMI may have higher mortality…
Abstract Number: 3087 • 2016 ACR/ARHP Annual Meeting
Association of Weight Loss with Improved Disease Activity in Patients with Rheumatoid Arthritis
David J. Kreps^1,2, Florencia Halperin³, Sonali P. Desai³, Zhi Zhang³, Elena Losina³, Elizabeth W. Karlson¹, Bonnie L. Bermas¹ and Jeffrey A. Sparks⁴, ¹Rheumatology, Immunology and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, ²Boston University, Boston, MA, ³Division of Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, ⁴Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA
Background/Purpose : Obesity has been associated with worsened RA outcomes and increased disease activity. However, few longitudinal studies have investigated whether weight loss might improve…
Abstract Number: 3193 • 2016 ACR/ARHP Annual Meeting
Is an Intensive Diet and Exercise Regimen Cost-Effective for Obese and Overweight Patients with Symptomatic Knee OA?
Elena Losina¹, Karen C. Smith², A. David Paltiel³, Lisa Gale Suter⁴, Jeffrey N. Katz⁵ and Stephen P. Messier⁶, ¹Orthopedics, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, ²Orthopaedics, Brigham and Women's Hospital, Boston, MA, ³Yale University, New Haven, CT, ⁴Medicine, Rheumatology, Yale University, New Haven, CT, ⁵Orthopaedics, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, ⁶Department of Health and Exerc, Wake Forest University, Winston-Salem, NC
Background/Purpose: About 50% of persons with knee OA are obese. Quality-adjusted life-year losses due to knee OA and obesity exceed 3.5 per person. The results…
Abstract Number: 397 • 2016 ACR/ARHP Annual Meeting
Comorbidities Associated with Pediatric Psoriatic Arthritis
Cynthia Manos¹, Rui Xiao², Alexis Ogdie³, Timothy Brandon⁴ and Pamela F. Weiss^5,6, ¹Rheumatology, Children's Hospital of Philadelphia, Philadelphia, PA, ²Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, PA, ³University of Pennsylvania, Philadelphia, PA, ⁴Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA, ⁵Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, ⁶Division of Rheumatology, Center for Pediatric Clincial Effectiveness, Children's Hospital of Philadelphia, Philadelphia, PA
Background/Purpose: In adults, psoriatic arthritis (PsA) is associated with an increased prevalence of obesity, hypertension, and diabetes. It is not yet known if pediatric patients…
Abstract Number: 39 • 2015 ACR/ARHP Annual Meeting
Baseline Obesity and Subsequent Weight Loss Are Independently Associated with Cardiovascular Mortality in Established Rheumatoid Arthritis
Bryant R. England¹, Joshua F. Baker², Harlan Sayles³, Kaleb Michaud^4,5, Liron Caplan⁶, Lisa A. Davis⁶, Grant W. Cannon⁷, Brian Sauer⁸, E. Blair Solow⁹, Andreas Reimold¹⁰, Gail S. Kerr¹¹, Pascale Schwab¹² and Ted R. Mikuls¹³, ¹Division of Rheumatology, Department of Internal Medicine, University of Nebraska Medical Center, Omaha, NE, ²Rheumatology, University of Pennsylvania, Philadelphia, PA, ³University of Nebraska Medical Center, Omaha, NE, ⁴Internal Medicine, Division of Rheumatology, University of Nebraska Medical Center, Omaha, NE, ⁵National Data Bank for Rheumatic Diseases, Wichita, KS, ⁶Div of Rheumatology, Univ of CO Denver School of Med, Aurora, CO, ⁷Division of Rheumatology, Salt Lake City VA Medical Center and University of Utah, Salt Lake City, UT, ⁸Salt Lake City VA Medical Center and University of Utah, Salt Lake City, UT, ⁹Rheumatology, UT Southwestern Medical Center, Dallas, TX, ¹⁰Rheumatology, VAMC, University of Texas Southwestern Medical Center, Dallas, TX, ¹¹VAMC, Georgetown University, Washington, DC, ¹²Div Arth & Rheum Dis, Oregon Health & Sci Univ OP09, Portland, OR, ¹³Medicine, University of Nebraska Medical Center, Omaha, NE
Background/Purpose: In the general population, higher body mass index (BMI) is associated with cardiovascular (CV) disease. However, an obesity paradox has been observed in rheumatoid…
Abstract Number: 234 • 2015 ACR/ARHP Annual Meeting
Weight Variables and Their Association with Serum Urate Concentrations and Hyperuricemia in Young Adults
Angelo L. Gaffo^1,2, David R. Jacobs Jr.³, Huifen Wang⁴ and Kenneth G. Saag⁵, ¹Rheumatology, Birmingham VA Medical Center, Birmingham, AL, ²Medicine, University of Alabama at Birmingham, Birmingham, AL, ³Epidemiology, University of Minnesota, Minneapolis, MN, ⁴Nutritional Epidemiology Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA, ⁵University of Alabama at Birmingham, Birmingham, AL
Background/Purpose: How body weight, anthropometric parameters, and their changes are associated with serum urate concentrations and hyperuricemia remains unclear. The CARDIA study has been following…
Abstract Number: 321 • 2015 ACR/ARHP Annual Meeting
Effects of Bariatric Surgery on Long-Term Quality of Life Outcomes for Obese Patients with Osteoarthritis
Ankita Satpute¹, Deepak L. Bhatt², Sangeeta Kashyap³, Philip Schauer⁴, Colin O'Rourke⁵, James Bena⁵ and M. Elaine Husni⁶, ¹Case Western Reserve University School of Medicine, Cleveland, OH, ²Brigham and Women’s Hospital Heart & Vascular Center, Boston, MA, ³Endocrinology, Diabetes and Metabolism, Cleveland Clinic Foundation, Cleveland, OH, ⁴General Surgery, Cleveland Clinic Foundation, Cleveland, OH, ⁵Department of Quantitative Health Sciences, Cleveland Clinic Foundation, Cleveland, OH, ⁶Rheumatology Dept A50, Cleveland Clinic Foundation, Cleveland, OH
Background/Purpose: Osteoarthritis (OA) remains a debilitating burden for patients and a challenge to their physicians, as there is no known cure. Obesity has been linked…
Abstract Number: 331 • 2015 ACR/ARHP Annual Meeting
Are Metabolic Factors Associated with Shoulder Osteoarthritis? a Multicentric Study.
Pierre-Antoine Juge¹, Laure Bérard², Salma Kotti³, Tabassome Simon⁴, Francis Berenbaum⁵, Geoffroy Nourissat⁶ and Jérémie Sellam⁷, ¹Rheumatology Department, Saint-Antoine Hospital, Paris, France, ²Rheumatology Department, Le Havre Hospital, Le Havre, France, ³Unité de Recherche Clinique de l’Est Parisien, Saint-Antoine Hospital, Paris, France, ⁴Unité de Recherche Clinique de l'Est Parisien URCEST, Saint-Antoine Hospital, AP-HP, Univ Paris 06, Paris, France, ⁵Rheumatology, Inserm UMRS_938, AP-HP, St Antoine Hospital, Univ Paris 06, DHU i2B, Paris, France, ⁶Orthopedic surgery, Clinique des Maussins & St-Antoine Hospital AP-HP, Paris, France, ⁷Rheumatology and Inserm UMRS_938, AP-HP, St Antoine Hospital, Univ Paris 06, DHU i2B, Paris, France
Background/Purpose: Aging, trauma and obesity are the 3 main risk factors for knee, hip and hand osteoarthritis (OA). It is noteworthy that risk factors for…
Abstract Number: 688 • 2015 ACR/ARHP Annual Meeting
Clinical Improvements in Psoriasis and Psoriatic Arthritis with Surgical Weight Loss
Monica Sethi¹, Christine Ren-Fielding², Ana Clara Caminer^3,4, Jose U. Scher⁵ and Soumya M. Reddy⁶, ¹Department of Surgery, Division of Bariatric Surgery, New York University School of Medicine, New York, NY, ²Department of Surgery, New York University School of Medicine, New York, NY, ³Rheumatology, Facultad de Ciencias Médicas, Universidad Nacional de Rosario, Rosario, Argentina, ⁴Rheumatology, Sanatorio Parque, Rosario, Argentina, ⁵Department of Medicine, Division of Rheumatology, New York University School of Medicine, New York, NY, ⁶Division of Rheumatology, New York University School of Medicine, New York, NY
Background/Purpose: Obesity is more prevalent among patients with psoriasis and psoriatic arthritis (PsA). This correlation appears to be related to fat tissue-driven systemic inflammation. Although…
Abstract Number: 1586 • 2015 ACR/ARHP Annual Meeting
Weight Loss in Obese Rheumatoid Arthritis (RA) Patients Improves Disease Activity without Modifying RA Treatment
Elisa Gremese¹, Maria Rita Gigante¹, Barbara Tolusso¹, Anna Laura Fedele¹, Silvia Canestri¹, Barbara Aquilanti², Clara Di Mario¹, Luca Petricca¹, Stefano Alivernini¹ and Gianfranco Ferraccioli¹, ¹Division of Rheumatology, Institute of Rheumatology, Catholic University of the Sacred Heart, Rome, Italy, ²Dietology Service, Association Columbus, Catholic University of the Sacred Heart, Rome, Italy
Background/Purpose: Obesity is recognized as a systemic, low-grade inflammatory state and the adipose tissue as an endocrine organ releasing pro-inflammatory cytokines. On the other hand,…
Abstract Number: 1699 • 2015 ACR/ARHP Annual Meeting
Obesity and Pediatric Psoriatic Arthritis
Cynthia Manos¹, Timothy Brandon², Rui Xiao³, Jon M. Burnham⁴ and Pamela F. Weiss¹, ¹Rheumatology, Children's Hospital of Philadelphia, Philadelphia, PA, ²Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA, ³Department of Pediatrics, Division of Biostatistics, Children's Hospital of Philadelphia, Philadelphia, PA, ⁴Pediatric Rheumatology, Children's Hospital of Philadelphia, Philadelphia, PA
Background/Purpose: Studies in adults have shown a significant association between obesity and psoriatic arthritis. The association of obesity with pediatric psoriatic arthritis is unknown.…
Abstract Number: 2274 • 2015 ACR/ARHP Annual Meeting
Increasing Moderate-to-Vigorous Activity and Decreasing Sedentary Time Are Associated with 2-Year Weight Loss in Obese Persons with or at Risk for Knee Osteoarthritis
Christine Pellegrini¹, Jing Song², Rowland W. Chang³, Pamela Semanik⁴, Julia (Jungwha) Lee⁵, Linda S. Ehrlich-Jones⁶, Daniel Pinto⁷ and Dorothy D. Dunlop⁸, ¹Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, ²Institute for Healthcare Studies, Northwestern University, Chicago, IL, ³Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, ⁴College of Nursing, Rush University, Chicago, IL, ⁵Department of Preventive Medicine, Biostatistics Collaboration Center, Northwestern University Feinberg School of Medicine, Chicago, IL, ⁶Research CROR, Rehabilitation Institute Chicago, Chicago, IL, ⁷Department of Physical Therapy & Human Movement Sciences, Northwestern University, Chicago, IL, ⁸Institute for Healthcare Studies, Northwestern University Feinberg School of Medicine, Chicago, IL
Background/Purpose: Moderate-to-vigorous physical activity (MVPA) is recommended for weight loss; however it is unclear how activity or sedentary changes influence long-term weight loss in obese…

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