Abstracts tagged "obesity and rheumatoid arthritis (RA)"

Abstract Number: 1907 • 2018 ACR/ARHP Annual Meeting
High Serum Adiponectin Associates with the Incidence of Rheumatoid Arthritis in Obese Subjects
Cristina Maglio¹, Yuan Zhang², Christian Herder³, Anna Rudin⁴ and Lena Carlsson⁵, ¹Dep. of Rheumatology and Inflammation Research and Wallenberg Centre for Molecular and Translational Medicine, The Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden, ²Dep. of Rheumatology and Inflammation Research, The Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden, ³German Diabetes Center, Düsseldorf, Germany, ⁴Dept of Rheumatology and Inflammation Research, The Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden, ⁵Department of Molecular and Clinical Medicine, The Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden
Background/Purpose: Adiponectin, a cytokine mainly produced by the adipose tissue, plays an important role in several metabolic and inflammatory processes. In obese subjects, serum adiponectin…
Abstract Number: 503 • 2018 ACR/ARHP Annual Meeting
Waist Circumference Based Abdominal Obesity Versus Body Mass Index in Rheumatoid Arthritis: Influence on the Risk of Diabetes and Cardiovascular Disease
Gulsen Ozen¹, Sofia Pedro² and Kaleb Michaud^1,2, ¹Rheumatology, University of Nebraska Medical Center, Omaha, NE, ²FORWARD, The National Databank for Rheumatic Diseases, Wichita, KS
Background/Purpose: Adipose tissue deposited around the mesentery is highly associated with insulin resistance and cardiovascular disease (CVD). Compared to BMI, waist circumference (WC) has been…
Abstract Number: 1460 • 2018 ACR/ARHP Annual Meeting
Plasma Mir-146a-5p Associates with Beneficial Body Composition and Plasma Metabolic Profiles in Rheumatoid Arthritis
Brian J. Andonian¹, Ching-Heng Chou², Virginia B. Kraus², William E. Kraus³ and Kim M. Huffman⁴, ¹Department of Medicine, Division of Rheumatology and Immunology, Duke University, Durham, NC, ²Duke Molecular Physiology Institute, Duke University, Durham, NC, ³Medicine, Duke University, Durham, NC, ⁴School of Medicine, Division of Rheumatology, Immunology and Molecular Physiology and Durham VA Medical Center, Duke University, Durham, NC
Background/Purpose: In rheumatoid arthritis (RA), sarcopenic obesity is associated with significant cardiometabolic disease and mortality. Biomarkers of disease activity in RA and obesity are complicated…
Abstract Number: 1487 • 2018 ACR/ARHP Annual Meeting
Correlation between Cytokine Levels and Power-Doppler Ultrasound Activity Is BMI Dependent, and Different in ACPA Positive and ACPA Negative RA with Wrist Arthritis
Ottar Gadeholt¹, Erin Arnold², Corinne Gorman³, Tobias Mueller⁴ and William Arnold², ¹Rheumatology/Immunology, Medical Clinic II, University Clinic Wuerzburg, Wuerzburg, Germany, ²Orthopedics and Rheumatology of the North Shore, Skokie, IL, ³Orthopaedics & Rheumatology of the North Shore, Skokie, IL, ⁴Department of Bioinformatics, University of Wuerzburg, Wuerzburg, Germany
Background/Purpose: Multiple cytokines are assumed to be involved in RA pathogenesis. It has been hypothesized that ACPA-negative RA with wrist affection constitutes a separate entity.…
Abstract Number: 1508 • 2018 ACR/ARHP Annual Meeting
Relationship between BMI and Lower Limb Dysfunction in Japanese Female Patients with Rheumatoid Arthritis (the data from NinJa registry)
Toshihiro Matsui¹, Atsushi Hashimoto¹, Kimio Masuda² and Shigeto Tohma³, ¹Rheumatology, National Hospital Organization Sagamihara Hospital, Sagamihara, Japan, ²Department of Rehabilitation Medicine, National Hospital Organization Sagamihara Hospital, Sagamihara, Japan, ³National Hospital Organization Tokyo Hospital, Sagamihara, Japan
Background/Purpose: To clarify the relationship between Body Mass Index (BMI) and lower limb dysfunction in patients with rheumatoid arthritis (RA). Methods: The data of 8,332…
Abstract Number: 1906 • 2018 ACR/ARHP Annual Meeting
Abdominal Obesity and Risk of Developing Rheumatoid Arthritis in Women
Bing Lu¹, Jeffrey A. Sparks², Sara K. Tedeschi³, Susan Malspeis⁴, Karen Costenbader² and Elizabeth Karlson⁵, ¹Brigham & Women's Hospital and Harvard Medical School, Boston, MA, ²Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA, ³Division of Rheumatology, Immunology and Allergy, Brigham & Women's Hospital, Harvard Medical School, Boston, MA, ⁴Rheumatology, Immunology and Allergy, Brigham & Women's Hospital and Harvard Medical School, Boston, MA, ⁵Brigham and Women's Hospital and Harvard Medical School, Boston, MA
Background/Purpose: Being overweight or obese increases the risk of rheumatoid arthritis (RA) among women, particularly among those diagnosed with RA at earlier ages. Abdominal obesity…
Abstract Number: 392 • 2017 ACR/ARHP Annual Meeting
Effects of Synthetic Dmards on the Insulin Resistance and Obesity Associated with Rheumatoid Arthritis: An Obese Mouse Model of Arthritis
Nuria Barbarroja¹, Ivan Arias de la Rosa², Miriam Ruiz-Ponce¹, Sergio Rodriguez-Cuenca³, Maria Carmen Abalos-Aguilera², Yolanda Jiménez-Gómez¹, Patricia Ruiz-Limon², Carlos Perez-Sanchez¹, Eduardo Collantes-Estévez¹, Antonio Vidal-Puig³, Alejandro Escudero-Contreras² and Chary Lopez-Pedrera¹, ¹Rheumatology service, IMIBIC/Reina Sofia Hospital/University of Cordoba, Cordoba, Spain, ²Rheumatology Service, IMIBIC/Reina Sofia Hospital/University of Cordoba, Cordoba, Spain, ³Metabolic Research Laboratories, Wellcome Trust-MRC Institute of Metabolic Science, Addenbroke’s Hospital, University of Cambridge, Cambridge, United Kingdom
Background/Purpose: Numerous studies have demonstrated the closely association between rheumatoid arthritis (RA) and metabolic complications such as obesity and insulin resistance (IR). Thus, there is…
Abstract Number: 2376 • 2017 ACR/ARHP Annual Meeting
Weight Histories Expose the Systematic Underestimation of the Risks of Obesity on Mortality in Rheumatoid Arthritis
Joshua Baker¹, Bryant R. England², Ted R. Mikuls³ and Kaleb Michaud⁴, ¹Medicine/Rheumatology, University of Pennsylvania, Philadelphia, PA, ²Division of Rheumatology & Immunology, Department of Internal Medicine, Nebraska-Western IA VA Health Care System & University of Nebraska Medical Center, Omaha, NE, ³Internal Medicine, Division of Rheumatology, University of Nebraska Medical Center, Omaha, NE, ⁴University of Nebraska Medical Center, Omaha, NE
Background/Purpose: Emerging evidence suggests that long-term weight loss is an important confounder that results in an underestimation of the risks of obesity in chronic illness.…
Abstract Number: 2377 • 2017 ACR/ARHP Annual Meeting
Impact of Body Mass Index and Weight Loss on Incident Disability in Patients with Rheumatoid Arthritis
Joshua Baker¹, Ted R. Mikuls², Bryant R. England³, Michael D. George⁴, Grant Cannon⁵, Harlan Sayles⁶, Brian Sauer⁵, Liron Caplan⁷ and Kaleb Michaud⁶, ¹Medicine/Rheumatology, University of Pennsylvania, Philadelphia, PA, ²Internal Medicine, Division of Rheumatology, University of Nebraska Medical Center, Omaha, NE, ³Division of Rheumatology & Immunology, Department of Internal Medicine, Nebraska-Western IA VA Health Care System & University of Nebraska Medical Center, Omaha, NE, ⁴Division of Rheumatology, University of Pennsylvania, Philadelphia, PA, ⁵Salt Lake City VA Medical Center and University of Utah, Salt Lake City, UT, ⁶University of Nebraska Medical Center, Omaha, NE, ⁷Division of Rheumatology, University of Colorado School of Medicine, Aurora, CO
Background/Purpose: Obese patients with rheumatoid arthritis (RA) have greater disability in cross-sectional studies. There are no long-term studies that assess trajectories of disability among individuals…
Abstract Number: 23 • 2016 ACR/ARHP Annual Meeting
Incidence of Non Alcoholic Fatty Liver Disease By Key Risk Factors Among Patients with Rheumatoid Arthritis
Ani John¹, Angela Witt Prehn², Hebatullah Tawfik², George W. Reed³ and Joel Kremer⁴, ¹School of Health Sciences, Walden University, Minneapolis, CA, ²School of Health Sciences, Walden University, Minneapolis, MN, ³Corrona, LLC, Southborough, MA, ⁴The Center for Rheumatology, Albany Medical College, Albany, NY
Background/Purpose: The prevalence and characteristics of patients with nonalcoholic fatty liver disease (NAFLD) have not been well characterized in the RA population. The purpose of…
Abstract Number: 507 • 2016 ACR/ARHP Annual Meeting
Comparison of Body Mass Index, Anti-Citrullinated Peptides Antibodies Status and Periodontal Condition in First Degree Relatives Individuals to Rheumatoid Arthritis
Sonia Unriza-Puin¹, Wilson Bautista-Molano^2,3, Gloria Lafaurie⁴, Rafael R. Valle-Oñate⁵, Phillipe Chalem⁶, Lorena Chila³, Juan Manuel Bello⁷ and Consuelo Romero Sanchez^3,8, ¹Unit of Oral Basic Investigation, School of Dentistry, Universidad El Bosque, Bogota, Colombia, ²Rheumatology Department School of Medicine HMC / UMNG, Bogotá, Colombia, ³Unit of Oral Basic Investigation, School of Dentistry, Universidad El Bosque, Bogotá, Colombia, ⁴Unit of Oral Basic Investigation-UIBO, School of Dentistry, Universidad El Bosque, Bogotá, Colombia, ⁵Rheumatology, Rheumatology Department School of Medicine HMC / UMNG, Bogota, Colombia, ⁶Fundación Instituto de Reumatología Fernando Chalem, Bogotá, Colombia, ⁷Rheumatology Department School of Medicine HMC / UMNG, Bogota, Colombia, ⁸Rheumatology, School of Medicine HMC / UMNG, Bogota, Colombia
Background/Purpose: Association studies in rheumatoid arthritis (RA) have been focused in the pre-clinical phases of the disease in asymptomatic individuals with higher risk to develop…
Abstract Number: 510 • 2016 ACR/ARHP Annual Meeting
C-Reactive Protein and Disease Activity in Rheumatoid Arthritis: Impact of Obesity and Adiposity
Michael D. George¹, Jon T. Giles², Patricia P. Katz³, Said Ibrahim⁴, Grant W. Cannon⁵, Bryant R. England⁶, Liron Caplan⁷, Brian Sauer⁸, Kaleb Michaud⁹, Ted R Mikuls¹⁰ and Joshua F. Baker¹, ¹Rheumatology, University of Pennsylvania, Philadelphia, PA, ²Rheumatology, Columbia University Medical Center, NY, NY, ³Medicine/Rheumatology, University of California, San Francisco, San Francisco, CA, ⁴Medicine, University of Pennsylvania, Philadelphia, PA, ⁵Salt Lake City VA Medical Center and University of Utah Division of Rheumatology, Salt Lake City, UT, ⁶Internal Medicine, University of Nebraska Medical Center, Omaha, NE, ⁷Denver Veterans Affairs Medical Center and UC Denver SOM, Denver, CO, ⁸IDEAS Center and Division of Epidemiology, HSR&D SLC VA Medical Center and University of Utah, Salt Lake City, UT, ⁹University of Nebraska Medical Center, Omaha, NE, ¹⁰Internal Medicine, Division of Rheumatology, University of Nebraska Medical Center, Omaha, NE
Background/Purpose: C-reactive protein (CRP) is used to assess disease activity in rheumatoid arthritis (RA), and previous work suggests that adiposity also impacts CRP levels. This…
Abstract Number: 1446 • 2016 ACR/ARHP Annual Meeting
High Fat Diet Alleviates Antigen-Induced Arthritis Severity in Male Mice By Enhancing Both Treg and B10 Cells
Yubin Luo¹, Cecilia Engdahl², Yi Zaho³, Yi Liu⁴, Georg Schett⁵ and Aline Bozec⁶, ¹Department of Rheumatology & Immunology,, West China Hosptial, Sichuan University, Chengdu, China, ²Department of Internal Medicine 3 and Institute for Clinical Immunology, Friedrich-Alexander-University Erlangen-Nuremberg (FAU), Erlangen, Germany, ³Department of Rheumatology & Immunology, West China Hosptial, Sichuan University, Chengdu, China, ⁴Department of Rheumatology and Immunology, West China Hospital of Sichuan University, Chengdu, China, ⁵Department of Internal Medicine III, Institute for Clinical Immunology,, Friedrich-Alexander-University Erlangen-Nuremberg (FAU), Erlangen, Germany, ⁶Department Clinic of Medicine 3 - Immunology und Rheumatology, University of Erlangen-Nuremberg, Department Clinic of Medicine 3 - Immunology und Rheumatology, Erlangen, Germany, Erlangen, Germany
Background/Purpose: Obesity is associated with many chronic diseases. However, evidence regarding obesity’s impact on rheumatoid arthritis (RA) initiation and development remains controversial. Recent studies indicate…
Abstract Number: 2490 • 2016 ACR/ARHP Annual Meeting
Impact of Obesity Activity Indices and Therapeutic Dosage in Patients with Rheumatoid Arthritis in Dominican Republic
E Rodríguez-Bautista¹, V Rosario¹, R Peña-Blanco², R Munoz-Louis¹, Y Cruz-Rojas¹, I Paulino-Izquierdo¹, J Paula-Mateo¹, T Valdez-Lorie² and R Alba-Fériz¹, ¹Rheumatology, Hospital Docente Padre Billini (HDPB), Santo Domingo, Dominican Republic, ²Rheumatology, Hospital Docente Universitario Dr. Francisco E. Moscoso Puello (HFMP), Santo Domingo, Dominican Republic
Background/Purpose: Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic arthritis that mainly affects small and medium joints. It is the most common form…
Abstract Number: 38 • 2015 ACR/ARHP Annual Meeting
Impact of Obesity on the Disease Course of Rheumatoid Arthritis
Yang (Linda) Liu¹, Gilaad Kaplan², Bertus Eksteen³ and Cheryl Barnabe¹, ¹Cumming School of Medicine, University of Calgary, Calgary, AB, Canada, ²Division of Gastroenterology, University of Calgary, Calgary, AB, Canada, ³Division of Hepatology, University of Calgary, Calgary, AB, Canada
Background/Purpose: Obesity results in a higher risk for the development of rheumatoid arthritis (RA) but is associated with less radiographic damage. The evidence for the…

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