Abstracts tagged "Neurologic involvement"

Abstract Number: 1693 • 2019 ACR/ARP Annual Meeting
Biological Therapy in Neurobehçet: Multicenter Study of 31 Patients
Iñigo Gonzalez-Mazon¹, Lara Sanchez-Bilbao ², Jose Luis Martín-Varillas ², Belén Atienza-Mateo ², Vanesa Calvo Río ², Santos Castañeda ³, Esther Vicente-Rabaneda ⁴, Olga Maiz ⁵, ana blanco ⁵, Clara Moriano ⁶, Elvira Díez ⁶, JL Andreu ⁷, Concepción Delgado-Beltrán ⁸, Marta Loredo-Martinez ⁸, Javier Narváez ⁹, Angel Ramos-Calvo ¹⁰, Francisca Sivera ¹¹, E. Raya ¹², Norberto Ortego Centeno ¹², Jose luis callejas rubio ¹², Anahy Brandy-Garcia ¹³, Alejandro Olivé-Marqués ¹⁴, Sabela Fernández ¹⁵, Ricardo Gómez De La Torre ¹⁶, Iñaki Torre-Salaberri ¹⁷, Julio Sanchez ¹⁸, A. Urruticoechea-Arana ¹⁹, Eva salgado-Pérez ²⁰, Rafael Melero ²¹, Olga Martinez ²², Susana Romero-Yuste ²³, Miguel A Gonzalez-Gay ² and Ricardo Blanco ², ¹Rheumatology, Hospital Universitario Marques de Valdecilla, Santander, Cantabria, Spain, ²Rheumatology, Hospital Universitario Marques de Valdecilla, Santander, Spain, ³Rheumatology, Hospital Universitario La Princesa, Madrid, Madrid, Spain, ⁴Rheumatology Department, Hospital Universitario La Princesa, Madrid, Spain, ⁵Rheumatology, Hospital Universitario Donostia, san sebastian, Pais Vasco, Spain, ⁶Complejo Asistencial Universitario de León, León, Castilla y Leon, Spain, ⁷HU Puerta del Hierro, Madrid, ⁸H. Clinico Lozano Blesa Zaragoza, Zaragoza, Aragon, Spain, ⁹Rheumatology Department, Hospital Universitari de Bellvitge, Barcelona, Catalonia, Spain, ¹⁰Rheumatology, Complejo Hospitalario de Soria, soria, Castilla y Leon, Spain, ¹¹Hospital General Universitario de Elda, Elda, Spain, ¹²Hospital San Cecilio, Granada, Andalucia, Spain, ¹³Hospital Universitari Germans Trias i Pujol, Badalona, Spain, ¹⁴Hospital Universitari Germans Trias i Pujol, Badalona, Catalonia, Spain, ¹⁵Hospital Universitario San Agustín, Avilés, Asturias, Spain, ¹⁶Department of Internal Medicine, Hospital Universitario Central de Asturias, Oviedo, Spain, Oviedo, Spain, ¹⁷BASURTO UNIVERSITY HOSPITAL, Bilbao, Spain, ¹⁸H. 12 de Octubre, Madrid, Spain, ¹⁹HU Can Misses, Ibiza, Spain, ²⁰Complejo Hospitalario Universitario de Ourense, Ourense, Galicia, Spain, ²¹Complexo Hospitalario Universitario de Vigo, Vigo, Galicia, Spain, ²²Hospital Clínico Universitario de Salamanca, Salamanca, Spain, ²³Complejo Hospitalario Universitario Pontevedra, Pontevedra, Galicia, Spain
Background/Purpose: Behçet's disease (BD) is a variable vessel vasculitis and typically presents with mucocutaneous involvement. However, any organ can be affected, being the neurological affectation…
Abstract Number: 1736 • 2019 ACR/ARP Annual Meeting
Cognitive Impairment in Childhood-Onset Systemic Lupus Erythematosus: Early Detection with MRI Spectroscopy and Its Association with MOG Antibodies
Huseyin Kilic ¹, Sezgin Sahin ², Mekiya Filiz Toprak ³, Gokce Hale Atay ⁴, Kubra Yilmaz ¹, Amra Adrovic ⁵, Kenan Barut ⁶, Esin Ozturk Isik ⁴, Erdem Tuzun ⁷, Osman Kizilkilic ⁸, Sema Saltik ¹ and Ozgur Kasapcopur⁹, ¹Department of Pediatric Neurology, Cerrahpasa Medical School, Istanbul University-Cerrahpasa, Istanbul, Turkey, Istanbul, Turkey, ²Department of Pediatric Rheumatology, Cerrahpasa Medical School, Istanbul University-Cerrahpasa, Istanbul, Turkey, Istanbul, Istanbul, Turkey, ³Department of Pediatric Neurology, Bezmialem Vakif University, School of Medicine, Istanbul, Turkey, Istanbul, Turkey, ⁴Institute of Biomedical Engineering, Boğaziçi University, Istanbul, Turkey, Istanbul, Turkey, ⁵Department of Pediatric Rheumatology, Cerrahpasa Medical School, Istanbul University-Cerrahpasa, Istanbul, Turkey, Istanbul, Turkey, ⁶Department of Pediatric Rheumatology, Cerrahpasa Medical School, Istanbul University-Cerrahpasa, Istanbul, Turkey, İstanbul, Istanbul, Turkey, ⁷Department of Neuroscience, Aziz Sancar Institute of Experimental Medicine, Istanbul University, Istanbul, Turkey, Istanbul, Turkey, ⁸Department of Neuroradiology, Cerrahpasa Medical School, Istanbul University-Cerrahpasa, Istanbul, Turkey, Istanbul, Turkey, ⁹Department of Pediatric Rheumatology, Istanbul University-Cerrahpasa, Istanbul, Turkey, Istanbul, Turkey
Background/Purpose: Systemic lupus erythematosus (SLE) is a chronic inflammatory disease characterized by the presence of various autoantibodies. Unnoticed and progressive cognitive impairment may develop in…
Abstract Number: 1228 • 2018 ACR/ARHP Annual Meeting
Spine Immobilization and Neurological Complications in Vertebral Osteomyelitis: Results from a Multicenter Prospective Observational Study
Géraldine Bart¹, Guillaume Coiffier², Oriane Merot³, Emmanuel Hoppe⁴, Marion Couderc⁵, Denis Mulleman⁶, Gregoire Cormier⁷, Jean Marc Ziza⁸ and Benoit Le Goff¹, ¹Rheumatology, Nantes University Hospital, Nantes, France, ²Rheumatology, Rennes University Hospital, Rennes, France, ³rheumatology unit, Saint Nazaire Hospital, Saint Nazaire, France, ⁴Angers University Hospital, Angers, France, ⁵Rheumatology, CHU Gabriel Montpied, Clermont-Ferrand, France, ⁶Université François-Rabelais de Tours, CNRS 7292, Tours, France, ⁷Service de Rhumatologie, CHD de la Roche-Sur-Yon, La Roche-Sur-Yon, France, ⁸Medecine Interne-Rhumatologie, Groupe hospitalier Diaconesses-Croix-Saint-Simon, Paris, France
Background/Purpose: In a previous work, we showed that neurological complication can occur in up to 40% of patients with vertebral osteomyelitis (VO). Bed rest and…
Abstract Number: 2256 • 2018 ACR/ARHP Annual Meeting
Rheumatic Diseases Associated with Neuromyelitis Optica Spectrum Disorders (NMOSD): Prevalence, Clinical, Laboratory and Imaging Characteristics
Milena Rodriguez Alvarez¹, Su Zhaz Leon¹, Fernando Cuascut², Naureen Kabani³, Joshy Pathiparampil³, Kristaq Koci⁴, Manjeet Bhamra⁵, Latoya Freeman⁴, Alexandra Kreps⁶, Justin Levinson⁶, Sophia Francis⁶, Vinodkumar Velayndhan⁶, Steve Xie⁷, Abhimanyu Amarnani⁶, Helen Valsamis⁸, Yaacov Anziska⁶, Ellen M. Ginzler⁹ and Isabel M. McFarlane⁹, ¹Rheumatology, SUNY Downstate, Brooklyn, NY, ²Neurology, SUNY Downstate, Brooklyn, NY, ³Internal Medicine, SUNY Downstate Medical Center, Brooklyn, NY, ⁴Medicine, SUNY Downstate Medical Center, Brooklyn, NY, ⁵Medicine, SUNY Downstate, Brooklyn, NY, ⁶SUNY Downstate, Brooklyn, NY, ⁷NYC Health + Hospitals Kings County, Brooklyn, NY, ⁸Neurology, NYC Health + Hospitals Kings County, Brooklyn, NY, ⁹Rheumatology, SUNY Downstate Medical Center, Brooklyn, NY
Background/Purpose: NMOSD are autoimmune disorders characterized by optic neuritis (ON), longitudinal extensive transverse myelitis (LETM), and other clinical features. Aquaporin 4 antibodies (AQP4 Ab) have…
Abstract Number: 1270 • 2017 ACR/ARHP Annual Meeting
Comparison of Clinical and Serological Features of Juvenile and Adult-Onset Neuropsychiatric Lupus in Spanish Patients
Sandra Garrote-Corral¹, Alina Boteanu², Walter A. Sifuentes-Giraldo¹, Antía García-Fernández¹, María Luz Gámir-Gámir¹ and Antonio Zea Mendoza¹, ¹Rheumatology, Hospital Universitario Ramón y Cajal, Madrid, Spain, ²Rheumatology, Hospital Universitario Ramon y Cajal, Madrid, Spain
Background/Purpose: Neuropsychiatric (NP) manifestations are a main cause of morbidity and mortality in juvenile-onset systemic lupus erythematosus (jSLE). Some studies suggest that they are more…
Abstract Number: 1851 • 2017 ACR/ARHP Annual Meeting
Improving Walking Ability in Degenerative Lumbar Spinal Stenosis: A Randomized Trial Comparing 2 Self-Management Training Programs
Carlo Ammendolia¹, Pierre Côté², Danielle Southerst³, Michael Schneider⁴, Brian Budgell³, Claire Bombardier⁵, Gillian Hawker⁶ and Y. Raja Rampersaud⁷, ¹Surgery, University of Toronto, Toronto, ON, Canada, ²University of Ontario Institute of Technology, Toronto, ON, Canada, ³Canadian Memorial Chiropractic College, Toronto, ON, Canada, ⁴University of Pittsburgh, Pittsburgh, PA, ⁵Toronto General Hospital Research Institute, University Health Network, Toronto, ON, Canada, ⁶Professor, Full SGS Member Department of Medicine, University of Toronto Chief of Medicine, Women's College Hospital 76 Grenville Street 8th Floor East, Room 815, University of Toronto, Toronto, ON, Canada, ⁷University of Toronto, Toronto, ON, Canada
Background/Purpose: Degenerative lumbar spinal stenosis (DLSS) is a leading cause of pain, disability and loss of independence in older adults. It is caused by age…
Abstract Number: 944 • 2016 ACR/ARHP Annual Meeting
A New Syndrome in the Spectrum of Cryopyrin-Associated Periodic Syndromes (CAPS) Caused By the Novel R918Q NLRP3 Mutation
Gineth Pinto-Patarroyo¹, Daniel L. Kastner¹, Andrew Griffith², H. Jeffrey Kim², Camilo Toro³, Ariane Soldatos⁴, John Butman⁵, Bibi Bielekova⁴, JaeJin Chae⁶, Ivona Aksentijevich¹, Hal M. Hoffman⁷, Lori Broderick⁸, Tina Romeo⁹, Anne Jones¹, Jessica Ratay² and Susannah Wargo², ¹Inflammatory Disease Section, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, ²National Institute of Deafness and Other Communication Disorders, Bethesda, MD, ³NIH Undiagnosed Diseases Program, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, ⁴National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, ⁵Diagnostic radiology department, Warren Grant Magnuson Clinical Center, Bethesda, MD, ⁶Inflammatory disease section, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, ⁷Pediatric Allergy, Immunology and Rheumatology, University of California at San Diego/Rady Children Hospital, La Jolla, CA, ⁸Pediatric allergy, Immunology and Rheumatology, University of California at San Diego/Rady Children Hospital, La Jolla, CA, ⁹National Human Genome Research Institute, National Institutes of Health, Bethesda, MD
Background/Purpose: Mutations in NLRP3 cause 3 different dominantly inherited autoinflammatory syndromes: familial cold autoinflammatory syndrome (FCAS), Muckle-Wells syndrome (MWS), and neonatal-onset multisystem inflammatory disease (NOMID).…
Abstract Number: 1348 • 2016 ACR/ARHP Annual Meeting
Neuromyelitis Optica: Patient Characteristics and Treatment Patterns Among Rheumatologists Versus Non-Rheumatologists
Sabrina Gmuca¹, Rui Xiao², Amy T. Waldman³, Jeffrey S. Gerber⁴ and Pamela F. Weiss⁵, ¹Pediatric Rheumatology, The Children's Hospital of Philadelphia, Philadelphia, PA, ²Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, PA, ³Pediatric Neurology, The Children's Hospital of Philadelphia, Philadelphia, PA, ⁴The Children's Hospital of Philadelphia, Philadelphia, PA, ⁵Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA
Background/Purpose: Neuromyelitis optica (NMO) is an immune-mediated inflammatory disorder of the central nervous system that has been associated with systemic autoimmunity often cared for by…
Abstract Number: 1768 • 2016 ACR/ARHP Annual Meeting
Fatigue in SLE Is Associated with Neuropsychiatric Involvement, Pain, Impaired Sleep and a Reduced Quality of Life
Andreas Jönsen¹, Pia C Sundgren², Jessika Nystedt³, Petra Nilsson³, Åsa Lilja⁴ and Anders A. Bengtsson¹, ¹Lund University, Department of Clinical Sciences, Rheumatology, Lund, Sweden, ²Department of Diagnostic Radiology, Lund University, Lund, Sweden, ³Department of Clinical Sciences, Neurology, Lund University, Lund, Sweden, ⁴Center for Primary Health Care Research, Lund University, Malmö, Sweden
Background/Purpose: Fatigue is a major patient complaint in SLE, often severely impacting quality of life and activities including work. In this study, we analyze neuropsychiatric…
Abstract Number: 143 • 2015 ACR/ARHP Annual Meeting
Fiber Optic Intubation in Patients with Rheumatoid Arthritis Who Had a Surgical Procedure
Gurjot Basra¹, Marylou Cardenas-Turanzas², Tayab Andrabi³, Katy Elizabeth French³, Bobby Bellard³, William A Murphy Jr.⁴, Maria A. Lopez-Olivo⁵ and Maria E. Suarez-Almazor⁵, ¹Baylor College of Medicine, Houston, TX, ²Department of General Internal Medicine, The University of Texas, MD Anderson Cancer Center, Houston, TX, ³Anesthesiology, The University of Texas, MD Anderson Cancer Center, Houston, TX, ⁴Radiology, The University of Texas, MD Anderson Cancer Center, Houston, TX, ⁵General Internal Medicine, The University of Texas, MD Anderson Cancer Center, Houston, TX
Background/Purpose: Fiber optic intubation is the preferred method of airway management during anesthetic procedures for patients with RA. The purpose of our study was to…
Abstract Number: 2030 • 2015 ACR/ARHP Annual Meeting
MRI Changes Associated with Neurological Compromise in Acute Pyogenic Vertebral Osteomyelitis: A Retrospective Study of 121 Patients
Géraldine Bart¹, Herve Redon², David Boutoille³, Olivier Hamel⁴, Yves Maugars¹ and Benoit Le Goff¹, ¹Rheumatology, Nantes University Hospital, Nantes, France, ²Nouvelles cliniques nantaises, Nantes, France, ³Infectious diseases, Nantes University Hospital, Nantes, France, ⁴Neurosurgery, Nantes University Hospital, Nantes, France
Background/Purpose: Vertebral osteomyelitis is a rare but potentially severe disease: previous works have estimated that neurological complications occurred in up to 59% cases. However, these works…
Abstract Number: 2640 • 2013 ACR/ARHP Annual Meeting
VERY LONG-TERM Effects Of The “4 PLUS2 Infusion PROTOCOL” Of Rituximabalone In Patients With HCV-Associatedmixed Cryoglobulinemia With Diffusemembranoproliferative Glomerulonephritis,Severe Polyneuropathy and Necrotic Ulcersof Skin
Dario Roccatello¹, Savino Sciascia¹, Simone Baldovino² and Daniela Rossi¹, ¹Department of Rare, Immunologic, Hematologic and Immunohematologic Diseases, Centro di Immunopatologia e Documentazione su Malattie rare, Torino, Italy, ²Centro di Ricerche di Immunologia Clinica ed Immunopatologia e Documentazione su Malattie Rare (CMID), Università di Torino, Torino, Italy
Background/Purpose: Mixed cryoglobulinemia syndrome (MCs) is a systemic vasculitischaracterized by multiple organ involvement due to the vascular deposition ofIgMk/IgG cryoglobulins. B cells expansion usually triggered…
Abstract Number: 2632 • 2013 ACR/ARHP Annual Meeting
Long Term Outcome Of Neuro-Behçet’s Disease
Nicolas Noel¹, Remy Bernard², Bertrand Wechsler³, Matthieu Resche-Rigon², Du Boutin⁴, Jean-Charles Piette⁵, Aurélie Drier⁶, Didier Dormont⁶, Patrice Cacoub⁴ and David Saadoun⁷, ¹APHP, Hopital Bicêtre, Service de Médecine Interne et Immunologie Clinique, Le Kremlin Bicêtre, France, ²Biostatistics, Hopital Saint-Louis, Paris, France, ³Internal Medecine, Assistance Publique-Hôpitaux de Paris, Hopital Pitié-Salpétrière, Paris, France, ⁴Internal Medicine, Assistance Publique-Hôpitaux de Paris, Hopital Pitié-Salpétrière, Paris, France, ⁵Groupe Hospitalier Pitié Salpétrière, Service de Médecine Interne, DHU i2B, Paris, France, ⁶Neuroradiology, Assistance Publique-Hôpitaux de Paris, Hopital Pitié-Salpétrière, Paris, France, ⁷DHU 2iB Internal Medicine Referal Center for Autoimmune diseases Pitie Hospital, Paris, France
Background/Purpose: Neurological involvement occurs in 5.3 to up to 59% of patients with Behçet’s disease (BD). Although the clinical and imaging features of neuro-Behçet’s disease…
Abstract Number: 2036 • 2012 ACR/ARHP Annual Meeting
Children’s Hospital of Pittsburgh Pediatric Onset En Coup De Sabre and Parry-Romberg Syndrome Cohort
Kristin M. Brown¹, Darren Smith², Christina Kelsey³, Katherine Kurzinski⁴ and Kathryn S. Torok⁵, ¹Pediatric Rheumatology, University of Pittsburgh, Pittsburgh, PA, ²Plastic and Reconstructive Surgery, university of Pittsburgh Division of Plastic and Reconstructive Surgery, Children's Hospital of Pittsburgh, Pittsburgh, ³Pediatric Rheumatology, Univ of Pittsburgh Med Ctr, Pittsburgh, PA, ⁴Pediatric Rheumatology, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA, ⁵Pediatric Rheumatology, Scleroderma Center of Pittsburgh, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA
Background/Purpose: Localized scleroderma is an autoimmune disease characterized by disfiguring thickening and fibrosis of the skin and underlying soft tissues; the majority of cases have…
Abstract Number: 1436 • 2012 ACR/ARHP Annual Meeting
Application of European League Against Rheumatism Recommendations for the Management of Systemic Lupus Erythematosus Patients with Neuropsychiatric Involvement May Limit Unnecessary Diagnostic Testing and Curve Intensification of Immunosuppressive Therapy of Unclear Benefit
Cristina Pamfil¹, Antonios Fanouriakis², Argyro Repa³, Maria Melissourgaki², Prodromos Sidiropoulos³, Ileana Filipescu¹, Mirela Rinzis⁴, Simona Rednic⁴, George Bertsias³ and Dimitrios Boumpas⁵, ¹Rheumatology, University of Medicine and Pharmacy, Cluj-Napoca, Romania, ²Rheumatology, Clinical Immunology, and Allergy, University of Crete, Iraklion, Greece, ³Rheumatology, Clinical Immunology, and Allergy, University of Crete, Heraklion, Greece, ⁴Rheumatology, Emergency County Clinical Hospital Cluj Napoca, Cluj-Napoca, Romania, ⁵Panepistimio Kritis, Rethymnon, Greece
Background/Purpose: Systemic lupus erythematosus (SLE) patients may experience a wide variety of neurological and psychiatric manifestations (neuropsychiatric [NP] SLE [NPSLE]), which pose diagnostic and therapeutic…

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