ACR Meeting Abstracts

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Abstracts tagged "Myopathies"

  • Abstract Number: 1140 • ACR Convergence 2024

    Pulmonary Hypertension in Hospitalized Patients with Dermatomyositis & Polymyositis: A Nationwide Cohort Analysis

    Saman Tanveer1, Daksh Ahluwalia1, Fatima Tanveer2, Abdullah Saeed3, Almurtada Razok4 and Faria Sami5, 1John H. Stroger Jr. Hospital of Cook County, Chicago, IL, 2CMH Lahore Medical and Dental College, Lahore, Pakistan, 3CMH Lahore Medical and Dental College, Lahore, Punjab, Pakistan, 4John H Stroger Jr Hospital of Cook County, Chicago, IL, 5University of Alabama, Chicago, IL

    Background/Purpose: Dermatomyositis (DM) and polymyositis (PM) are idiopathic inflammatory myopathies characterized by muscles inflammation, proximal muscle weakness and extramuscular manifestations. A particularly challenging extramuscular manifestation…
  • Abstract Number: 2052 • ACR Convergence 2024

    Role of Scleroderma/myositis-related Autoantibodies Detected by Immunoblot to the Diagnosis of Systemic Autoimmune Rheumatic Diseases in 410 Patients from a Single Referral Center

    Carmen Secada Gómez1, Diana Prieto-Peña2, Mónica Renuncio-García3, Juan Irure-Ventura4, Marcos Lopez-Hoyos5 and Ricardo Blanco-Alonso6, 1Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Spain, 2Division of Rheumatology, Hospital Universitario Marqués de Valdecilla. IDIVAL, Immunopathology group, Santander, Cantabria, Spain, 3Division of Immunology, Hospital Universitario Marqués de Valdecilla, Immunopathology Group, IDIVAL, Santander, Spain, 4Division of Immunology, Hospital Universitario Marqués de Valdecilla. Immunopathology group, IDIVAL, Santander, Cantabria, Spain, 5Division of Immunology, Hospital Universitario Marqués de Valdecilla. Immunopathology group, IDIVAL, Santander, Spain, 6Division of Rheumatology, Hospital Universitario Marqués de Valdecilla. IDIVAL, Immunopathology group, Santander, Spain

    Background/Purpose: In clinical practice, immunoblot assays are being used more frequently as a diagnostic tool for systemic autoimmune rheumatic diseases (SARDs).Our aim was to evaluate the…
  • Abstract Number: 1141 • ACR Convergence 2024

    Defining a Novel Type of Myositis: Immune Mediated Megaconial Myopathy (IMMM)

    Teerin Liewluck1, Ashley Santilli2, Oliver Ni3, Margherita Milone2, Duygu Selcen2, Anahit Mehrabyan4, Arjun Seth5, Christine Hsieh5, Wasim Raslan6, Moayd Alkhalifah6, Raed Alenezi6, Stefan Nicolau7 and Pannathat Soontrapa8, 1Mayo Clinic, Rochester, MN, 2Mayo Clinic-Rochester, Rochester, MN, 3Hennepin Healthcare, Minneapolis, MN, 4University of North Carolina, Chapel Hill, NC, 5Northwestern University, Chicago, IL, 6Johns Hopkins Aramco Healthcare, Dhahran, Saudi Arabia, 7Nationwide Children’s Hospital, Columbus, OH, 8Siriraj Hospital, Mahidol University, Bangkok, Thailand

    Background/Purpose: To describe a novel type of myositis, immune mediated megaconial myopathy (IMMM),  pathologically characterized by giant mitochondria (megaconia).Methods: We reviewed the Mayo Clinic Muscle…
  • Abstract Number: 2058 • ACR Convergence 2024

    Association of Anti-Synthetase Antibody Subtypes with Radiographic Progression of Interstitial Lung Disease in Anti-Synthetase Syndrome: An Analysis of the CLASS Project Database

    Daphne Rivero Gallegos1, Francisca Bozan2, Sangmee Bae3, Giovanni Zanframundo4, Sara Faghihi-Kashani5, Iazsmin Bauer Ventura6, Eduardo Dourado7, Gianluca sambataro8, Akira Yoshida9, Tamera J Corte10, Francesco Bonella11, Tracy J Doyle12, david fiorentino13, Miguel Angel Gonzalez-Gay14, marie Hudson15, Masataka Kuwana16, Antonella Notarnicola17, Andrew Mammen18, Neil McHugh19, Frederick Miller20, Carlomaurizio Montecucco21, Chester Oddis22, Jorge Rojas-Serrano23, Jens Schmidt24, Carlo A. Scire25, Albert Selva-O’Callaghan26, Victoria Werth27, Rohit Aggarwal28 and Lorenzo Cavagna29, and CLASS project participating investigators, 1INER, Ciudad de México, Mexico State, Mexico, 2Hospital Clinico Universidad de Chile, Santiago, Chile, 3UCLA, Los Angeles, CA, 4Università di Pavia, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy, Milano, Italy, 5Division of Immunology and Rheumatology, Stanford University School of Medicine, Stanford, CA, San Francisco, CA, 6University of Chicago, Chicago, IL, 7Unidade Local de Saúde da Região de Aveiro, Aveiro, Portugal, 8University of Catania, Catania, Italy, 9Nippon Medical School Graduate School of Medicine, Bunkyo-ku, Tokyo, Japan, 10Royal Prince Alfred Hospital, University of Sydney, Sydney, Australia, 11Center for interstitial and rare lung diseases, Ruhrlandklinik, University of Duisburg-Essen, Essen, Germany, 12Brigham and Women's Hospital, West Roxbury, MA, 13Department of Dermatology, Stanford University School of Medicine, Stanford, CA, Palo Alto, CA, 14University of Cantabria, Fundación Jimenez Díaz, Madrid, Madrid, Spain, 15McGill University, Montreal, QC, Canada, 16Department of Allergy and Rheumatology, Nippon Medical School, Tokyo, Japan, Tokyo, Japan, 17Karolinska University Hospital and Karolinska Institutet, Stockholm, Stockholms Lan, Sweden, 18NIH, Bethesda, MD, 19University of Bath, Bath, United Kingdom, 20NIH, NIEHS, Chapel Hill, NC, 21IRCCS policlinico S. Matteo foundation, University of Pavia, Pavia, Italy, 22Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, 23National Institute of Respiratory Diseases, Ismael Cosío Villegas, Mexico City, Mexico, 24University Medical Center Goettingen, Göttingen, Germany, 25University of Milano Bicocca, Milan, Italy, 26Systemic Autoimmune Disease Unit, Vall d’Hebron Institute of Research, Barcelona, Spain, 27University of Pennsylvania, Wynnewood, PA, 28Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, USA, Pittsburgh, PA, 29University of Pavia and Fondazione IRCCS Policlinico San Matteo Hospital of Pavia, Pavia, Pavia, Italy

    Background/Purpose: In anti-synthetase syndrome (ASSD), clinical presentations vary from isolated interstitial lung disease (ILD) to systemic multi-organ manifestations. Several studies emphasize the crucial role of…
  • Abstract Number: 1144 • ACR Convergence 2024

    Autoantibody and Radiological Profiles as Prognostic Indicators in Idiopathic Inflammatory Myopathies: Insights into Mortality and Interstitial Lung Disease Development

    cristiana sieiro santos1, Miriam Retuerto2, Laura Sierra2, Jose Ordas Martínez3, Paula Pérez García2, Pedro Baenas2, Clara Moriano Morales2 and Elvira Díez Álvarez4, 1Rheumatology Department, Complejo Asistencial Universitario de León, León, Spain, Leon, Spain, 2Complejo Asistencial Universitario de León, León, Spain, 3Complejo Asistencial Universitario de Leon, Leon, 4Complejo Asistencial Universitario de León, Leon, Spain

    Background/Purpose: The idiopathic inflammatory myopathies (IIMs) constitute a diverse group of acquired muscle disorders, often involving multiple organs such as the skin, heart, and lungs.…
  • Abstract Number: 2059 • ACR Convergence 2024

    The Rs35705950 Promoter Variant of Muc5b Is Associated with Usual Interstitial Pneumonia in Antisynthetase Syndrome

    Daphne Rivero Gallegos1, Mayra Mejía2, Karol J. Nava-Quiroz2, Heidegger N. Mateos-Toledo3, Héctor I. Rocha-González4, Juan C. Huerta-Cruz3, Espiridion Ramos-Martínez5, Gloria Pérez-Rubio3, Ingrid Fricke-Galindo3, Jorge Rojas-Serrano6 and Ramcés Falfán-Valencia3, 1INER, Ciudad de México, Mexico State, Mexico, 2INER, Mexico, Distrito Federal, Mexico, 3INER, Mexico City, Distrito Federal, Mexico, 4Instituto Politècnico Nacional, Mexico City, Distrito Federal, Mexico, 5UNAM, Ciudad de Mexico, Distrito Federal, Mexico, 6National Institute of Respiratory Diseases, Ismael Cosío Villegas, Mexico City, Mexico

    Background/Purpose: Rs35705950 variant in the MUC5B gene promoter is a critical genetic risk factor in idiopathic pulmonary fibrosis (IPF). It has been associated with usual…
  • Abstract Number: 1146 • ACR Convergence 2024

    Impact of COVID-19 on Myositis Testing Trends

    Angel Kevin Garza-Elizondo1, Rosa Icela Arvizu-Rivera2, Pablo Gamez-Siller3, Daniela Alejandra Salcedo-Soto4, Jesus Cardenas-de la Garza5, Gisela Garcia-Arellano6, Miguel Angel Villarreal-Alarcon2 and Dionicio Galarza-Delgado7, 1Division of Rheumatology, University Hospital "Dr. Jose Eleuterio Gonzalez", Universidad Autonoma de Nuevo Leon, San Nicolás de los Garza, Mexico, 2Division of Rheumatology, University Hospital "Dr. Jose Eleuterio Gonzalez", Universidad Autonoma de Nuevo Leon, Monterrey, Mexico, 3Facultad de Medicina UANL, Monterrey, Nuevo León, Mexico, 4Hospital Universitario Dr Jose Eleuterio Gonzalez, Monterrey, Mexico, 5Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, Mexico, 6Hospital Universitario \"Dr. José Eleuterio González\", Monterrey, Nuevo León, Mexico, 7UANL Hospital Universitario, Monterrey, Nuevo León, Mexico

    Background/Purpose: Idiopathic inflammatory myopathies (IIM), also known as myositis, are a group of heterogeneous autoimmune disorders that lead to muscle injury. Autoantibodies help make the…
  • Abstract Number: 2066 • ACR Convergence 2024

    Comparative Diagnostic Efficacy of Quantitative Measurement of Echo Intensity and Texture versus Qualitative Analysis of Ultrasound Images in Myositis

    Takeshi Yoshida1, Hiroki Yamazaki2, Naoko Takamatsu2, Yoshinori Taniguchi3, Taiki Nozaki4, masataka inoue5, Yoshitaka Kumon6, yuki matsumoto2, Yuki Kanazawa2, Masafumi Harada2, Ichizo Nishino7, Jemima Albayda8 and Yuishin Izumi2, 1Chikamori Hospital, Kochi, Kochi, Japan, 2Tokushima University School of Medicine, Tokushima, Japan, 3Kochi University School of Medicine, kochi, Japan, 4keio University School of Medicine, Tokyo, Japan, 5Hyogo Medical University, Nishinomiya, Japan, 6Chikamori Hospital, Kochi, Japan, 7National Center of Neurology and Psychiatry, Tokyo, Japan, 8Johns Hopkins School of Medicine, Baltimore, MD

    Background/Purpose: Recently, the role of imaging tests such as magnetic resonance imaging and ultrasound (US) in the diagnosis and classification of myositis has become increasingly…
  • Abstract Number: 1149 • ACR Convergence 2024

    Cause-Specific Proportionate Mortality Trends in Idiopathic Inflammatory Myopathies

    Ansaam Daoud1, Muhammad Shamim2, Loai Dweik3 and Haseeb Chaudhary4, 1Case Western Reserve University/University Hospitals, Akron, OH, 2University Hospitals/ Case Western Reserve University, Cuyahoga Falls, OH, 3Cleveland Clinic Akron General Internal Medicine, Akron, OH, 4Case Western Reserve University, Westlake, OH

    Background/Purpose: Idiopathic inflammatory myopathies (IIM) are associated with increased morbidity, mortality, and economic health burden compared to the general population despite advancements in overall disease management.…
  • Abstract Number: 2067 • ACR Convergence 2024

    Clinical and Laboratory Characterization of Overlap Connective Tissue Disease in Patients with Idiopathic Inflammatory Myopathies: Results from the MYOTReCSZ Cohort

    karina santana1, Jiram Torres Ruiz2, Diana Gómez-Martin3, María José Ostos-prado4, Yatzil Reyna-Juárez4, Beatriz Alcalá-Carmona4, Mariana Arroyo5 and Nancy R Mejía-Domínguez4, 1INCMNSZ, Ciudad de México, Distrito Federal, Mexico, 2INCMNSZ, Mexico, Federal District, Mexico, 3INCMNSZ, Mexico, Distrito Federal, Mexico, 4Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City, Distrito Federal, Mexico, 5Angeles Interlomas, Mexico, Distrito Federal, Mexico

    Background/Purpose: Idiopathic Inflammatory Myopathies (IIM) comprise systemic autoimmune dosorders which may occur in patients with other conective tissue diseases (CTD). The coexistence of IIM with…
  • Abstract Number: 1152 • ACR Convergence 2024

    Nailfold Videocapillaroscopy Abnormalities in Different Autoimmune Inflammatory Myopathy Subsets

    Thaisa Cotton1, Valérie Leclair2, Claudie Berger3, Yves Troyanov4, marie Hudson2 and Geneviève Gyger2, and Canadian Inflammatory Myopathy Study (CIMS), 1Université de Montréal, Montreal, QC, Canada, 2McGill University, Montreal, QC, Canada, 3Research Institute of the McGill University Health Centre, Montreal, QC, Canada, 4Centre hospitalier de l'Université de Montréal, Montreal, QC, Canada

    Background/Purpose: Nailfold videocapillaroscopy (NVC) alterations have mostly been described in autoimmune inflammatory myopathies (AIM) classified using Bohan and Peter criteria. The aim of this study…
  • Abstract Number: 2071 • ACR Convergence 2024

    Self-Efficacy Contributes to Better Health Outcomes in Patients of Idiopathic Inflammatory Myopathies: Insights from the COVAD 3 Dataset

    praggya yaadav1, Maria Rosa Pellico2, Anne-Marie Russell3, Aviya Lanis4, Elena Nikiphorou5, Ioannis Parodis6, Sreoshy Saha7, Manali Sarkar8, Jasmine Parihar9, Laura Andreoli10, Vikas Agarwal11 and Latika Gupta12, and COVAD Steering Committee, COVAD Study Group, 1Maharashtra Institute of Medical Sciences and Research, Latur, Aurangabad, India, 2University of Milan, Milan, Italy, 3Birmingham Regional Interstitial Lung Disease Service, University Hospitals Birmingham NHS Trust and Faculty of Life Sciences, University of Exeter, Exeter, UK, Birmingham, United Kingdom, 4Seattle Children's Hospital, Seattle, WA, 5King's College London, London, United Kingdom, 6Karolinska Institutet, Karolinska University Hospital; Örebro University, Solna, Sweden, 7Mymensingh Medical College, Mymensingh, Bangladesh, 8MGM Medical College, Navi Mumbai, Maharashtra, India, 9All India Institute of Medical Science, New Delhi, Delhi, India, 10University of Brescia, Brescia, Italy, 11Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India, 12Royal Wolverhampton NHS Trust, Wolverhampton, United Kingdom

    Background/Purpose: Self-efficacy is crucial for chronic disease management. Given the increasing prevalence of chronic diseases, encouraging patients to actively manage their disease may be an…
  • Abstract Number: 1155 • ACR Convergence 2024

    Stratification of Cancer Risk in Idiopathic Inflammatory Myopathies. Application of the IMACS Guidelines to Enhance Screening

    Miriam Retuerto Guerrero1, Clara Moriano2, cristiana sieiro santos3 and elvira Diez álvarez4, 1Complejo Asistencial Universitario de León, Leon, Spain, 2Hospital León, LEON, Spain, 3Rheumatology Department, Complejo Asistencial Universitario de León, León, Spain, Leon, Spain, 4Complejo Asistencial Universitario de Leon, Leon

    Background/Purpose: Idiopathic inflammatory myopathies (IIM) carry an elevated risk of cancer incidence. Recently published International Guidelines for IIM-associated cancer screening from the Myositis Assessment and…
  • Abstract Number: 2073 • ACR Convergence 2024

    Ultrasound Findings of Activity in Patients with Inflammatory Myopathies and Clinical and Laboratory Comparison

    Carina Soto-Fajardo1, Alejandra Espinosa-Orantes2, Alejandra Enríquez-Luna3, Fabian Carranza Enriquez4, Tabata Cano-Gamez3, Ana Mora-Rosas5, Rosa Elena Cervantes-Ramirez5, Karen Contreras-Castillo5, Jiram Torres Ruiz6, Diana Gómez-Martin7 and Carlos Pineda8, 1Instituto Nacional de Rehabilitacion "Luis Guillermo Ibarra Ibarra", Mexico City, Mexico, 2Instituto Nacional de Rehabilitación "Luis Guillermo Ibarra Ibarra", Ciudad de México, Mexico, 3Instituto Nacional de Rehabilitacion, Mexico, Distrito Federal, Mexico, 4Instituto Nacional de Rehabilitación \"Luis Guillermo Ibarra Ibarra\", Ciudad de México, Mexico, 5Instituto Nacional de Rehabilitación "Luis Guillermo Ibarra Ibarra", Mexico, Distrito Federal, Mexico, 6INCMNSZ, Mexico, Federal District, Mexico, 7INCMNSZ, Mexico, Distrito Federal, Mexico, 8Instituto Nacional de Rehabilitacion, Mexico City, Distrito Federal, Mexico

    Background/Purpose: Muscle ultrasound (MUS) is a non-invasive tool that may explore the extent of muscle abnormalities and contribute to early diagnosis and follow-up of patients…
  • Abstract Number: 1159 • ACR Convergence 2024

    Anti-synthetase Syndrome (ASSD) Related Interstitial Lung Disease (ILD) in Comparison to Non-ASSD Related ILDs: Analysis from the “Classification Criteria for Anti-synthetase Syndrome (CLASS)” Project Database

    Sangmee Bae1, Francisca Bozan2, Daphne Rivero Gallegos3, Giovanni Zanframundo4, Sara Faghihi-Kashani5, iazsmin Ventura6, Eduardo Dourado7, Aravinthan Loganathan8, Gianluca sambataro9, Akira Yoshida10, Francesco Bonella11, Tamera J Corte12, Tracy J Doyle13, david fiorentino14, Miguel Angel Gonzalez-Gay15, marie Hudson16, Masataka Kuwana17, Antonella Notarnicola18, Andrew Mammen19, Neil McHugh20, Frederick Miller21, Carlomaurizio Montecucco22, Chester Oddis23, Jorge Rojas-Serrano24, Jens Schmidt25, Carlo Scire26, Albert Selva-O’Callaghan27, Victoria Werth28, Lorenzo Cavagna29 and Rohit Aggarwal30, 1UCLA, Los Angeles, CA, 2Hospital Clinico Universidad de Chile, Santiago, Chile, 3INER, Ciudad de México, Mexico State, Mexico, 4Università di Pavia, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy, Milano, Italy, 5Division of Immunology and Rheumatology, Stanford University School of Medicine, Stanford, CA, San Francisco, CA, 6Section of Rheumatology, University of Chicago, Chicago, IL, 7Unidade Local de Saúde da Região de Aveiro, Aveiro, Portugal, 8RUH, Middle Park, Queensland, Australia, 9University of Catania, Catania, Italy, 10Nippon Medical School Graduate School of Medicine, Bunkyo-ku, Tokyo, Japan, 11Center for interstitial and rare lung diseases, Ruhrlandklinik, University of Duisburg-Essen, Essen, Germany, 12Royal Prince Alfred Hospital, University of Sydney, Sydney, Australia, 13Brigham and Women's Hospital, West Roxbury, MA, 14Department of Dermatology, Stanford University School of Medicine, Stanford, CA, Palo Alto, CA, 15University of Cantabria, Fundación Jimenez Díaz, Madrid, Madrid, Spain, 16McGill University, Montreal, QC, Canada, 17Department of Allergy and Rheumatology, Nippon Medical School, Tokyo, Japan, Tokyo, Japan, 18Karolinska University Hospital and Karolinska Institutet, Stockholm, Stockholms Lan, Sweden, 19NIH, Bethesda, MD, 20University of Bath, Bath, United Kingdom, 21NIH, NIEHS, Chapel Hill, NC, 22IRCCS policlinico S. Matteo foundation, University of Pavia, Pavia, Italy, 23Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, 24National Institute of Respiratory Diseases, Ismael Cosío Villegas, Mexico City, Mexico, 25University Medical Center Goettingen, Göttingen, Germany, 26University of Milano Bicocca, Milan, Italy, 27Internal Medicine Department, Universitat Autònoma de Barcelona, Barcelona, Spain, 28University of Pennsylvania, Wynnewood, PA, 29University of Pavia, Pavia, Italy, 30Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, USA, Pittsburgh, PA

    Background/Purpose: Anti-synthetase syndrome (ASSD) is a subset of idiopathic inflammatory myopathy characterized by autoantibodies directed against aminoacyl tRNA synthetases. Interstitial lung disease (ILD) can be…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

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