Abstracts tagged "Musculoskeletal"

Abstract Number: 1820 • ACR Convergence 2021
Efficacy of Deucravacitinib, an Oral, Selective Tyrosine Kinase 2 Inhibitor, in Musculoskeletal Manifestations of Active PsA in a Phase 2, Randomized, Double-Blind, Placebo-Controlled Trial
Philip Mease¹, Atul Deodhar², Désirée van der Heijde³, Frank Behrens⁴, Alan Kivitz⁵, Tom Lehman⁶, Lan Wei⁶, Marleen Nys⁷, Subhashis Banerjee⁶ and Miroslawa Nowak⁶, ¹Swedish Medical Center/Providence St. Joseph Health and University of Washington, Seattle, WA, ²Oregon Health & Science University, Portland, OR, ³Department of Rheumatology, Leiden University Medical Center, Meerssen, Netherlands, ⁴CIRI/Rheumatology and Fraunhofer Institute, Translational Medicine and Pharmacology ITMP, Goethe University, Frankfurt, Germany, ⁵Altoona Center for Clinical Research, Duncansville, PA, ⁶Bristol Myers Squibb, Princeton, NJ, ⁷Bristol Myers Squibb, Braine-l'Alleud, Belgium
Background/Purpose: Tyrosine kinase 2 (TYK2) is an intracellular kinase that mediates IL-23, IL-12, and IFNα/β signaling. Deucravacitinib is a novel, oral selective inhibitor of TYK2…
Abstract Number: 1053 • ACR Convergence 2021
Temporal Trends and Geographic Variations of Premature Mortality Related to Musculoskeletal(MSK) and Connective Tissue Disorders in the United States: A 20-Year Analysis from WONDER Database
Ikwinder Kaur¹, Mohsin Mughal², Hasan Mirza³, Harjot Jagdey⁴, Pankaj Bansal⁵, Eugenio Capitle⁶ and Fawad Aslam⁷, ¹Monmouth Medical Center, an affiliate of Rutgers health system, Long Branch, NJ, ²Monmouth Medical Center, Long Branch, NJ, ³Berkshire Medical Center, Pittsfield, MA, ⁴BronxCare Hospital, Bronx, NY, ⁵Mayo Clinic Health System, Eau Claire, WI, ⁶Rutgers New Jersey Medical School, New Brunswick, NJ, ⁷Mayo Clinic College of Medicine, Scottsdale, AZ
Background/Purpose: Musculoskeletal system and connective tissue disorders (arthropathies, systemic connective tissue disorders, soft tissue disorders) may contribute to premature mortality likely due to associated comorbidities…
Abstract Number: 2212 • 2019 ACR/ARP Annual Meeting
Patients with Axial Spondyloarthritis Have Abnormal Microarchitecture Despite Normal Areal Bone Mineral Density and Trabecular Bone Score by DXA
Dalit Ashany¹, Susan Goodman ², Haley Tornberg ¹, Donald McMahon ³, Douglas Mintz ⁴, Linda Russell ⁵ and Emily Stein ¹, ¹Hospital for Special Surgery, New York, NY, ²Hospital For Special Surgery/Weill Cornell Medicine, New York, NY, ³Donald J.McMahon Statistical Consulting, South Nyack, NY, ⁴Hospital for Special Surgery, Division of Radiology and Imaging, New York, ⁵Hospital for Special Surgery, New York
Background/Purpose: Axial Spondyloarthritis (axSpA) is characterized by abnormal bone formation that produces syndesmophytes, while paradoxically, inflammation causes increased bone resorption and skeletal fragility. Detection of…
Abstract Number: 185 • 2018 ACR/ARHP Annual Meeting
Evaluating Medical Student Confidence and Performance of the Pediatric Musculoskeletal Exam
Kimberly Hays¹, Natasha M. Ruth¹, Donna Kern², Paul J. Nietert³, Lutfiyya Muhammad³, Michele Knoll Friesinger⁴ and Patricia McBurney⁵, ¹Pediatric Rheumatology, Medical University of South Carolina, Charleston, SC, ²Family Medicine, Senior Associate Dean for Education, Medical University of South Carolina, Charleston, SC, ³Public Health Sciences, Medical University of South Carolina, Charleston, SC, ⁴Psychiatry and Behavioral Sciences, Assistant Dean for Assessment, Evaluation and Quality Improvement, Medical University of South Carolina, Charleston, SC, ⁵Pediatrics, Medical University of South Carolina, Charleston, SC
Background/Purpose: Children commonly present with musculoskeletal complaints to primary care providers who work in a busy practice with diverse populations. Musculoskeletal complaints may result from…
Abstract Number: 188 • 2018 ACR/ARHP Annual Meeting
Pediatric Trainee Confidence and Exposure to Rheumatology
Jessica Rutsky¹, Ann Salvator², Laura Ballenger³, Steven Cuff⁴ and Kyla Driest⁵, ¹Pediatrics, Nationwide Children's Hospital, Columbus, OH, ²Statistics, Nationwide Children's Hospital, Columbus, OH, ³Department of Rheumatology, Nationwide Children's Hospital, Columbus, OH, ⁴Sports Medicine, Nationwide Children's Hospital, Columbus, OH, ⁵Rheumatology, Nationwide Children's Hospital, Columbus, OH
Background/Purpose: A small number of previous studies show residents have low levels of confidence in rheumatologic and musculoskeletal (MSK) skills. The objective of this study…
Abstract Number: 399 • 2018 ACR/ARHP Annual Meeting
Musculoskeletal Comorbidities after Total Knee Replacement for Osteoarthritis
MaryAnn Zhang¹, Faith Selzer², Elena Losina¹, Jamie E. Collins³ and Jeffrey N. Katz¹, ¹Orthopaedic and Arthritis Center for Outcomes Research, Department of Orthopedic Surgery, Brigham & Women's Hospital, Boston, MA, ²Orthopedic Surgery, Orthopedic and Arthritis Center for Outcomes Research, Brigham and Women's Hospital, Boston, MA, ³Department of Orthopedic Surgery, Orthopedic and Arthritis Center for Outcomes Research, Brigham and Women's Hospital, Boston, MA
Background/Purpose: For patients undergoing total knee replacement (TKR) for osteoarthritis (OA), preoperative musculoskeletal (MSK) complaints in areas beyond the index knee are common; however, the…
Abstract Number: 69 • 2017 ACR/ARHP Annual Meeting
The Effect of Myostatin Inhibition on Bone Loss in Murine Osteoporosis Models
Tomoyuki Mukai¹, Takafumi Mito¹, Shunichi Fujita¹, Shoko Kodama¹, Akiko Nagasu¹, Teruki Sone², Shinichiro Nishimatsu³, Yutaka Ohsawa⁴, Yoshihide Sunada⁴ and Yoshitaka Morita¹, ¹Department of Rheumatology, Kawasaki Medical School, Kurashiki, Okayama, Japan, ²Department of Nuclear Medicine, Kawasaki Medical School, Kurashiki, Okayama, Japan, ³Department of Natural Sciences, Kawasaki Medical School, Kurashiki, Okayama, Japan, ⁴Department of Neurology, Kawasaki Medical School, Kurashiki, Okayama, Japan
Background/Purpose: Myostatin, also called as growth differentiation factor-8 (GDF-8), is a secreted member of TGF-β superfamily. Myostatin is a negative regulator of skeletal muscle mass…
Abstract Number: 157 • 2017 ACR/ARHP Annual Meeting
A Systematic Review of the Upper Limb Soft Tissue Comorbidities in Patients with Type 2 Diabetes Mellitus
Michelle C Papandony¹, Anita E Wluka², Ar Kar Aung³, Yuanyuan Wang¹, Sultana Monira Hussain⁴ and Flavia M Cicuttini¹, ¹Monash University, Department of Epidemiology and Preventive Medicine, Melbourne, Australia, ²Australia, Armadale, Australia, ³Department of General Medicine, Alfred Health, Melbourne, Australia, ⁴Monash University, Department of Epidemiology and Preventative Medicine, Melbourne, Australia
Background/Purpose: Soft tissue disorders affecting the upper limb are not commonly thought of as “classic” complications of type 2 diabetes mellitus. However, the majority of…
Abstract Number: 345 • 2017 ACR/ARHP Annual Meeting
The Patient Experience of Musculoskeletal Imaging Tests for Investigation of Inflammatory Arthritis: A Mixed Methods Study
Sandra Bourke^1,2, Nicola Dalbeth¹, William J. Taylor³, Anthony Doyle¹ and Merryn Gott¹, ¹University of Auckland, Auckland, New Zealand, ²Auckland district health board, Auckland, New Zealand, ³University of Otago, Wellington, New Zealand
Background/Purpose: Musculoskeletal (MSK) imaging is widely used in rheumatology for diagnosis and management of arthritis. Although the technical and performance properties of MSK imaging tests…
Abstract Number: 2050 • 2017 ACR/ARHP Annual Meeting
Analysis of Data Collected from Right and Left Limbs: Accounting for Dependence and Improving Statistical Efficiency in Musculoskeletal Research
Sarah Stewart¹, Janet Pearson², Keith Rome³, Nicola Dalbeth⁴ and Alain Vandal⁵, ¹School of Podiatry, Auckland University of Technology, Auckland, New Zealand, ²Auckland University of Technology, Auckland, Niger, ³School of Clinical Sceince, Health & Rehabilitation Research Institute, AUT University, Auckland, New Zealand, ⁴University of Auckland, Auckland, New Zealand, ⁵Counties Manukau District Health Board, Auckland, New Zealand
Background/Purpose: Statistical techniques used in musculoskeletal research often inefficiently account for paired-limb measurements or the relationship between measurements taken from multiple sites within limbs. This…
Abstract Number: 2418 • 2017 ACR/ARHP Annual Meeting
Tissue-Engineered Human Skeletal Muscle Model of Rheumatoid Arthritis
Catherine E. Oliver¹, Brittany N. Davis¹, James Hong¹, Kim M. Huffman² and George A. Truskey³, ¹Duke University, Durham, NC, ²School of Medicine, Division of Rheumatology, Immunology and Molecular Physiology and Durham VA Medical Center, Duke University, Durham, NC, ³BME, Duke University, Durham, NC
Background/Purpose: In rheumatoid arthritis (RA) reduced muscle function clearly contributes to disability. Due to a lack of accurate in vitro RA models, the underlying mechanisms…
Abstract Number: 105 • 2016 ACR/ARHP Annual Meeting
Regional Primary Care Rheumatology Networks for Patients with Rheumatic and Musculoskeletal Diseases: Need for a National Approach
Wilfred Peter¹, Florus van der Giesen², Cornelia H.M. van den Ende³, Joost Dekker⁴ and Thea P. M. Vliet Vlieland⁵, ¹Orthopeadics, Rehabilitation and Physical Therapy, Leids University Medical Center, Leiden, Netherlands, ²Orthopaedics, Rehabilitations and Physical Therapy, Leiden University Medical Centre, Leiden, Netherlands, ³Department of Rheumatology, Sint Maartenskliniek, Nijmegen, Netherlands, ⁴Rehabilitation Medicine, VU University Medical Center, Amsterdam, Netherlands, ⁵Orthopaedics, Rehabilitation and Physical Therapy, Leiden University Medical Center, Leiden, Netherlands
Background/Purpose: Regional primary care rheumatology networks of health professionals (HPs) are instituted to improve the quality of care for patients with rheumatic and musculoskeletal diseases…
Abstract Number: 1341 • 2016 ACR/ARHP Annual Meeting
Rheumatic and Musculoskeletal Immune-Related Adverse Events Due to Immune Checkpoint Inhibitors: A Systematic Literature Review
Laura Cappelli¹, Anna Kristina Gutierrez², Ami A. Shah³ and Clifton Bingham III⁴, ¹Medicine/Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, ²Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, ³Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, ⁴Johns Hopkins University, Baltimore, MD
Rheumatic and Musculoskeletal Immune-Related Adverse Events due to Immune Checkpoint Inhibitors: A Systematic Literature Review Background/Purpose: Immune checkpoint inhibitors (ICI) are effective treatments for advanced…
Abstract Number: 1187 • 2015 ACR/ARHP Annual Meeting
Comprehensive Musculoskeletal Exam Curriculum for Rheumatology Fellows
Sonali Narain, Shanthini Kasturi and VP Bykerk, Rheumatology, Hospital for Special Surgery, New York, NY
Background/Purpose: The musculoskeletal exam (MSKE) is an integral part of rheumatology training, both as a diagnostic aid, and as a predictor of disease activity. Formal…
Abstract Number: 2261 • 2015 ACR/ARHP Annual Meeting
Association Between Musculoskeletal Pain, Fat Mass and Fat Free Mass: Results from a Population-Based Study
Tiffany K. Gill¹, Tom P. Walsh^2,3, E. Michael Shanahan⁴ and Catherine Hill^5,6, ¹Medicine, The University of Adelaide, Adelaide, Australia, ²Medicine, Flinders University, Adelaide, Australia, ³Podiatry, Repatriation General Hospital, Adelaide, Australia, ⁴Flinders University, Adelaide, Australia, ⁵The Health Observatory, The University of Adelaide, Adelaide, Australia, ⁶Rheumatology Unit, The Queen Elizabeth Hospital, Woodville, Australia
Background/Purpose: Musculoskeletal pain has been shown to commonly occur at multiple sites. This is likely to have a greater impact on abilities to undertake activities…

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