Abstracts tagged "MRI"

Abstract Number: 537 • 2015 ACR/ARHP Annual Meeting
The Course of Bone Marrow Edema in Early Undifferentiated and Rheumatoid Arthritis; A Longitudinal MRI Study on Bone Level
W.P. Nieuwenhuis¹, H.W. van Steenbergen², W. Stomp³, T. Stijnen⁴, T. W. J. Huizinga¹, J.L Bloem³, D. van der Heijde¹, M. Reijnierse³ and A.H.M. van der Helm- van Mil², ¹Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ²Leiden University Medical Center, Leiden, Netherlands, ³Radiology, Leiden University Medical Center, Leiden, Netherlands, ⁴Medical Statistics, Leiden University Medical Center, Leiden, Netherlands
Background/Purpose: In rheumatoid arthritis (RA) patients, bone marrow edema (BME)-scores are associated with development of erosions. However, little is known on the course and outcome…
Abstract Number: 1445 • 2015 ACR/ARHP Annual Meeting
Physicians’ Perspectives on the Diagnosis and Treatment of Chronic Nonbacterial Osteomyelitis
Yongdong Zhao¹, Fatma Dedeoglu², Polly J. Ferguson³, Sivia Lapidus⁴, Ronald Laxer⁵, Suzanne C. Li⁶ and for the CARRA SVRD subcommittee, ¹Pediatric Rheumatology, Seattle Children's Hospital, Seattle, WA, ²Rheumatology, Boston Children's Hospital, Boston, MA, ³Dept of Pediatrics--Rheum, University of Iowa, Iowa City, IA, ⁴Pediatric Rheumatology, Goryeb Children's Hospital, Morristown, NJ, ⁵Division of Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada, ⁶Pediatrics, Joseph M Sanzari Children’s Hospital, Hackensack University Medical Center, Hackensack, NJ
Background/Purpose: Chronic nonbacterial osteomyelitis (CNO), also known as chronic recurrent multifocal osteomyelitis (CRMO), is an autoinflammatory bone disease of unknown cause that can result in…
Abstract Number: 2403 • 2015 ACR/ARHP Annual Meeting
Quadriceps Muscle Weakness and the Risk of Knee Cartilage Loss on MRI in a Population-Based Cohort with Knee Pain
Carson Chin¹, Eric C. Sayre², Ali Guermazi³, Savvas Nicolaou⁴, JM Esdaile⁵, Jacek A. Kopec⁶, Anona Thorne⁷, Joel Singer⁷, Hubert Wong⁷ and Jolanda Cibere⁸, ¹Department of Rheumatology, University of British Columbia, Vancouver, BC, Canada, ²Arthritis Research Canada, Richmond, BC, Canada, ³Boston University School of Medicine, Boston, MA, ⁴Radiology, University of British Columbia, Vancouver, BC, Canada, ⁵Rheumatology, Arthritis Research Canada, Richmond, BC, Canada, ⁶School of Population and Public Health, University of British Columbia and ARC, Vancouver, BC, Canada, ⁷Health Care and Epidemiology, University of British Columbia, Vancouver, BC, Canada, ⁸Rheumatology, University of British Columbia and ARC, Vancouver, BC, Canada
Background/Purpose: The objective of the study was to determine whether clinically assessed baseline quadriceps weakness predicts cartilage loss on MRI after 3 years. Methods: Subjects…
Abstract Number: 685 • 2015 ACR/ARHP Annual Meeting
Sacroiliitis Misdiagnosed As Spondyloarthritis: Clinical Analysis of 581 Cases
Feng Huang, Yanyan Wang, Zheng Zhao and Jianglin Zhang, Rheumatology, Chinese PLA General Hospital, Beijing, China
Background/Purpose: To study other disease conditions which can present with bone marrow edema of the sacroiliac joints mimicking spondyloarthritis(SpA). Methods: In a retrospective study of…
Abstract Number: 1713 • 2015 ACR/ARHP Annual Meeting
Fat Metaplasia on Sacroiliac Joint Magnetic Resonance Imaging at Baseline Is Associated with Spinal Radiographic Progression in Patients with Axial Spondyloarthritis
Kwi Young Kang¹, In Je Kim², Yeon Sik Hong³, Sung-Hwan Park⁴ and Ji Hyeon Ju⁵, ¹#505, Banpo-dong, Seocho-gu, Division of Rheumatology, Department of Internal Medicine, Catholic University of Korea, Seoul, South Korea, ²Division of Rheumatology, Department of Internal Medicine, Ewha Womans University School of Medicine, Seoul, South Korea, ³catholic University of Korea, Incheon, South Korea, ⁴Kangnam St Mary's Hospital, Seoul, South Korea, ⁵Division of Rheumatology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, South Korea
Background/Purpose: To study the relationship between inflammatory and structural lesions in the sacroiliac joints (SIJs) on MRI and spinal progression observed on conventional radiographs in…
Abstract Number: 2708 • 2015 ACR/ARHP Annual Meeting
Correlation of Peripheral Blood Th-17 and Th-1 with Synovitis and Osteitis By MRI in Recent Onset Rheumatoid Arthritis
Sukesh Edavalath¹, Ankita Singh¹, Namita Mohindra², Sunil Kumar² and Ramnath Misra¹, ¹Clinical Immunology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India, ²Radiodiagnosis, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
Background/Purpose: An increased expansion of Th17 cells in the synovial membrane have shown to play a key role in causing persistent synovitis leading to cartilage…
Abstract Number: 713 • 2015 ACR/ARHP Annual Meeting
Clinical and Imaging Efficacy of Etanercept in Early Non-Radiographic Axial Spondyloarthritis: 104-Week Treatment Results
Maxime Dougados¹, Désirée van der Heijde², Joachim Sieper³, Juergen Braun⁴, Gustavo Citera⁵, Filip van Den Bosch^6,7, Ronald Pedersen⁸, Randi Bonin⁹, Heather Jones¹⁰, Lisa Marshall¹⁰, Sameer Kotak¹¹, Isabelle Logeart¹², Bonnie Vlahos¹³, Jack F Bukowski⁹ and Walter Maksymowych¹⁴, ¹Rheumatology Department, Hôpital Cochin, Paris, France, ²Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ³Medical Department I, Rheumatology, Charité Universitätesmedizin Berlin, Berlin, Germany, ⁴Rheumazentrum Ruhrgebiet, Herne, Germany, ⁵Rheumatology, Consultorios Reumatológicos Pampa, Buenos Aires, Argentina, ⁶Department of Rheumatology, Ghent University Hospital, Ghent, Belgium, ⁷Rheumatology, Ghent University Hospital, Ghent, Belgium, ⁸Department of Biostatistics, Pfizer, Collegeville, PA, ⁹Clinical Affairs, Pfizer, Collegeville, PA, ¹⁰Inflammation Global Medical Affairs, Pfizer, Collegeville, PA, ¹¹Global Health and Value, Pfizer, New York, NY, ¹²Medical Affairs, Pfizer, France, Paris, France, ¹³GIPB - Clinical Sciences, Pfizer, Collegeville, PA, ¹⁴Department of Medicine, University of Alberta, Edmonton, AB, Canada
Background/Purpose: In the multiphase, randomized, placebo (PBO)-controlled EMBARK study (ClinicalTrials.gov identifier: NCT01258738), clinical signs/symptoms and MRI-measured inflammation were evaluated in patients with early, active non-radiographic…
Abstract Number: 1717 • 2015 ACR/ARHP Annual Meeting
Factors Associated with the Decision of the Rheumatologist to Order Sacro-Iliac Joints Magnetic Resonance Imaging (SI-MRI) or Order HLA-B27 Testing in Patients with Spondyloarthritis in Clinical Practice
Wilson Bautista-Molano^1,2, Robert Landewé³, Cesar Serna⁴, Rafael R. Valle⁵ and Désirée van der Heijde⁶, ¹Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands, Leiden, Netherlands, ²Department of Rheumatology, Faculty of Medicine HMC/UMNG, Bogota, Colombia, Bogotá, Colombia, ³Department of Rheumatology, Amsterdam Rheumatology Center, Amsterdam, The Netherlands, Amsterdam, Netherlands, ⁴Statistics and Mathematics Department, Universidad Central, Bogotá, Colombia, Bogotá, Colombia, ⁵Rheumatology/Immunology, Department of Rheumatology, Faculty of Medicine HMC/UMNG, Bogota, Colombia, Bogota, Colombia, ⁶Dept. of Rheumatology, Leiden University Medical Center, Leiden, Netherlands
Background/Purpose: Magnetic resonance imaging of sacroiliac joints (MRI-SI) and HLA-B27 testing are important tools in the diagnosis of spondyloarthritis (SpA). The aim of the study…
Abstract Number: 3177 • 2015 ACR/ARHP Annual Meeting
Whole-Body MRI: A Valuable Diagnostic Tool for the Assessment of Disease Damage in Juvenile Dermatomyositis
Clara Malattia¹, Agnese Beltramo¹, Isabella Buffoni¹, Annalisa Madeo¹, Francesca Magnaguagno², Stefania Viola¹ and Alberto Martini^1,3, ¹Istituto G Gaslini, Pediatria II, Reumatologia, Genova, Italy, ²Istituto G Gaslini, UO Radiologia Pediatrica, Genoa, Italy, ³Pediatria, Istituto G Gaslini, Pediatria II, Reumatologia, Genova, Italy
Background/Purpose: Although the prognosis of JDM has significantly improved during the past decade, some patients still experience persistent active disease, which potentially leads to irreversible…
Abstract Number: 714 • 2015 ACR/ARHP Annual Meeting
Baseline MRI and CRP As Predictors of Response to Etanercept in the Management of Patients with Non-Radiographic Axial Spondyloarthritis (nr-axSpA)
Matthew A. Brown¹, Paul A. Bird², Philip C. Robinson³, Philip J. Mease⁴, Filip van Den Bosch⁵, Christine Surian⁶, Zirke Wiid⁶, Heather Jones⁷, Annette Szumski⁸ and Lisa Marshall⁷, ¹Translational Research Institute, University of Queensland Diamantina Institute, Brisbane, Australia, ²University of New South Wales, Sydney, Australia, ³University of Queensland & Royal Brisbane and Women's Hospital, Brisbane, Australia, ⁴Rheumatology Research, Swedish Medical Center, Seattle, WA, ⁵Department of Rheumatology, Ghent University Hospital, Ghent, Belgium, ⁶Pfizer Australia, Sydney, Australia, ⁷Inflammation Global Medical Affairs, Pfizer, Collegeville, PA, ⁸Department of Biostatistics, Pfizer, Collegeville, PA
Background/Purpose: Treatment with tumor necrosis factor α (TNFα) inhibitors has been shown to be effective in improving disease activity and functional capacity in patients with…
Abstract Number: 1727 • 2015 ACR/ARHP Annual Meeting
MRI Vertebral Corner Inflammation Followed By Fat Deposition Is the Strongest Contributor to the Development of New Bone at the Same Vertebral Corner: A Multi-Level Longitudinal Analysis in Patients with Ankylosing Spondylitis
Pedro Machado¹, Xenofon Baraliakos², Désirée van der Heijde³, Juergen Braun² and Robert Landewé⁴, ¹Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ²Rheumazentrum Ruhrgebiet, Herne, Germany, ³Dept. of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ⁴Division of Clinical Immunology and Rheumatology, Academic Medical Center / University of Amsterdam, Amsterdam, Netherlands
Background/Purpose: Syndesmophyte formation in ankylosing spondylitis (AS) is still insufficiently understood. Previous studies have suggested an association between MRI vertebral corner inflammation (VCI) and vertebral…
Abstract Number: 3255 • 2015 ACR/ARHP Annual Meeting
Brain White Matter Integrity: A Future Biomarker for Rheumatoid Arthritis Related Fatigue?
Neil Basu¹, Marayam Alsyedalhashem², Mariella D'Allesandro³, Alison D. Murray², Daniel J. Clauw⁴ and Gordon D. Waiter², ¹Musculoskeletal Research Collaboration (Epidemiology Group), University of Aberdeen, Aberdeen, United Kingdom, ²Aberdeen Biomedical Imaging Centre, University of Aberdeen, Aberdeen, United Kingdom, ³Muscloskeletal Collaboration (Epidemiology Group), University of Aberdeen, Aberdeen, United Kingdom, ⁴Anesthesiology, University of Michigan, Ann Arbor, MI
Background/Purpose: Fatigue is a major burden among patients with rheumatoid arthritis (RA). The identification of reliable biomarkers would greatly enhance research in this challenging field. …
Abstract Number: 950 • 2015 ACR/ARHP Annual Meeting
In a Two-Year Double-Blind Randomized Controlled Multicenter Study, Chondroitin Sulfate Was Significantly Superior to Celecoxib at Reducing Cartilage Loss with Similar Efficacy at Reducing Disease Symptoms in Knee Osteoarthritis Patients
Jean-Pierre Pelletier¹, Jean Pierre Raynauld², André Beaulieu³, Louis Bessette⁴, Frédéric Morin⁵, Artur J Fernandes⁶, François Abram⁷, Marc Dorais⁸ and Johanne Martel-Pelletier⁹, ¹Rheumatology, Institut de recherche en rhumatologie de Montréal (IRRM), Montréal, QC, Canada, ²Osteoarthritis Research Unit, CRCHUM, Montreal, Montreal, QC, Canada, ³Centre de rhumatologie St-Louis, St. Louis, QC, Canada, ⁴Groupe de Recherche en Rhumatologie et Maladies Osseuses, Quebec, Quebec, QC, Canada, ⁵Centre de Recherche Musculo-squelettique, Trois-Rivières, Trois-Rivières, QC, Canada, ⁶Centre de Recherche Musculo-squelettique, Trois-Rivières, 6Rheumatology Division, Sherbrooke, Sherbrooke, QC, Canada, ⁷Medical Imaging Research & Development, ArthroLab Inc, Montreal, QC, Canada, ⁸StatSciences Inc., Montreal, Canada, Montreal, QC, Canada, ⁹Osteoarthritis Research Unit, University of Montreal Hospital Research Centre (CRCHUM),, Montreal, QC, Canada
Background/Purpose: In osteoarthritis (OA) treatment, although chondroitin sulfate (CS) was found in a number of studies using radiography to have a structure modifying effect, to…
Abstract Number: 1728 • 2015 ACR/ARHP Annual Meeting
Diffusion Weighted Imaging Is a Sensitive and Specific MRI Protocol for the Diagnosis and Assessment of Disease Severity in Ankylosing Spondylitis
Linda A. Bradbury¹, Kelly A. Hollis², Benoit Gautier², Sateesh Shankaranarayana³, Philip Robinson⁴, Nivene Saad³, Kim-Anh Lê Cao² and Matthew A. Brown¹, ¹The University of Queensland Diamantina Institute, Brisbane, Australia, ²University of Queensland Diamantina Institute, Brisbane, Australia, ³Princess Alexandra Hospital, Brisbane, Australia, ⁴Human Genetics Group, University of Queensland Diamantina Insititute, Brisbane, Australia
Background/Purpose: Diffusion weighted imaging (DWI) is an MRI protocol which assesses the random Brownian motion of water molecules in the tissue imaged; this motion is…
Abstract Number: 1006 • 2015 ACR/ARHP Annual Meeting
Incident Frequent Knee Pain Is Associated with Changes in Semi-Quantitative Imaging Biomarkers of Inflammation
C.Kent Kwoh¹, Michael J. Hannon², Tomoko Fujii³, Frank W Roemer⁴, Ali Guermazi⁵, David Hunter⁶, Felix Eckstein⁷ and Robert M. Boudreau⁸, ¹Department of Medicine, The University of Arizona Arthritis Center and Division of Rheumatology, Tucson, AZ, ²Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, ³University of Pittsburgh, Pittsburgh, PA, ⁴Department of Radiology, Boston University School of Medicine, Boston, MA, ⁵Boston University School of Medicine, Boston, MA, ⁶Rheumatology, Institute of Bone and Joint Research, Kolling Institute, University of Sydney, Sydney, Australia, ⁷Paracelsus Med Univ, Chondrometrics GmbH, Salzburg, Austria, ⁸Epidemiology, University of Pittsburgh, Pittsburgh, PA
Background/Purpose: The cause of knee pain in osteoarthritis (OA) is multi-factorial, and there is increasing evidence of the role of inflammation in OA. The goal…

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