Abstracts tagged "MRI"

Abstract Number: 1304 • 2015 ACR/ARHP Annual Meeting
Studying MR-Detected Inflammation in Symptom-Free Persons from the General Population to Generate Ramris-Based Reference Values
L. Mangnus¹, H.W. van Steenbergen², M. Reijnierse³ and A.H.M. van der Helm- van Mil¹, ¹Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ²Leiden University Medical Center, Leiden, Netherlands, ³Radiology, Leiden University Medical Center, Leiden, Netherlands
Background/Purpose: It is recommended by an EULAR imaging taskforce that MR-detected inflammation is useful in the diagnostic process of Rheumatoid Arthritis. This recommendation is based…
Abstract Number: 1817 • 2015 ACR/ARHP Annual Meeting
Myocardial Tissue Characterization with Native Myocardial T1 Mapping in SLE Patients with Chest Pain
Jaime Shaw¹, Mariko L. Ishimori², Vaneet K. Sandhu², Behzad Sharif³, Louise Thomson⁴, Debiao Li¹, Jay Schapira⁴, Daniel Wallace³, Noel Bairey Merz⁴, Michael Weisman³ and Daniel Berman⁴, ¹Biomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, ²Rheumatology, Cedars-Sinai Medical Center, Los Angeles, CA, ³Cedars-Sinai Medical Center, Los Angeles, CA, ⁴Cardiology, Cedars-Sinai Medical Center, Los Angeles, CA
Background/Purpose: SLE patients often exhibit signs and symptoms of cardiac ischemia with an overall increased prevalence of coronary artery disease (CAD), microvascular dysfunction and myocarditis…
Abstract Number: 1305 • 2015 ACR/ARHP Annual Meeting
Prevalence of MR-Detected Ramris-Defined Erosions in the General Population
L. Mangnus¹, H.W. van Steenbergen², M. Reijnierse³ and A.H.M. van der Helm- van Mil¹, ¹Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ²Leiden University Medical Center, Leiden, Netherlands, ³Radiology, Leiden University Medical Center, Leiden, Netherlands
Background/Purpose: The diagnostic value of Magnetic Resonance (MR) imaging for Rheumatoid Arthritis (RA) is undetermined. The main value of MR is its sensitive depiction of…
Abstract Number: 2024 • 2015 ACR/ARHP Annual Meeting
Replacing Radiographic Sacroiliitis By Structural Lesions on MRI of the Sacroiliac Joints in Two Early Axial Spa Cohorts: What Is the Impact on the Classification of Patients According to the ASAS Axial Spa Criteria?
Pauline Bakker¹, Rosaline van den Berg², Manouk de Hooge³, Zineb Ez-Zaitouni⁴, Miranda van Lunteren⁴, Karen M. Fagerli⁵, Roberta Ramonda⁶, Robert B. M. Landewé⁷, Maikel van Oosterhout⁸, Monique Reijnierse⁹, Floris van Gaalen¹, Pascal Claudepierre¹⁰, Daniel Wendling¹¹, Maxime Dougados¹² and Désirée van der Heijde¹³, ¹Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ²Leiden University Medical Center, Leiden, Netherlands, ³Department of Rheumatology, Leiden University Medical Centre, Leiden, Netherlands, ⁴Leiden University Medical Centre, Leiden, Netherlands, ⁵Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, ⁶Cattedra, Voc Rheumatology, University of Padua, Padova, Italy, ⁷Rheumatology, University Hospital Maastricht, Maastricht, Netherlands, ⁸Rheumatology, GHZ Hospital, Gouda, Netherlands, ⁹Radiology, Leiden University Medical Center, Leiden, Netherlands, ¹⁰Hôpital Henri Mondor, Créteil, France, ¹¹Université de Franche-Comté, Besançon, France, ¹²Paris-Descartes University, Paris, France, ¹³Department of Rheumatology, Leiden University Medical Center, Leiden, the Netherlands, Leiden, Netherlands
Background/Purpose: Conventional radiography of the sacroiliac joints (X-SI) is the most commonly used imaging technique to detect structural lesions in axial SpondyloArthritis (axSpA). However, a…
Abstract Number: 1306 • 2015 ACR/ARHP Annual Meeting
MRI Erosions in Undifferentiated Arthritis. Different Associations with the Collagen IIA N-Terminal Propeptide (PIIANP) and Galectin-3 in Pre-RA and Other Arthritides
Saida Farah Issa¹, Anne Duer², Mikkel Østergaard³, Hanne Lindegaard¹, Kim Hørslev-Petersen⁴, Merete Lund Hetland⁵, Jakob M. Møller⁶, Anne Friesgaard Christensen⁷ and Peter Junker¹, ¹Department of Rheumatology, Odense University Hospital, Odense, Denmark, ²Department of Rheumatology, Copenhagen University Hospital at Hvidovre, Hvidovre, Denmark, ³Center for Rheumatology and Spine Diseases, Glostrup Hospital, Copenhagen Center for Arthritis Research (COPECARE), Center for Rheumatology and Spine Diseases, Rigshospitalet - Glostrup, University of Copenhagen, Denmark, Glostrup, Denmark, ⁴Rheumatology, Research Unit at King Christian X Hospital for Rheumatic Diseases, Graasten, Denmark, ⁵DANBIO, Center for Rheumatology and Spine Diseases, Glostrup Univ Hospital, Glostrup, Denmark, ⁶Department of Radiology, Copenhagen University Hospital Herlev, Herlev, Denmark, ⁷Department of Rheumatology, Vejle Hospital, Vejle, Denmark
Background/Purpose: Galectin-3 has been implicated as a mediator of inflammation and erosive progression in animal arthritis and rheumatoid arthritis(RA). The type IIA procollagen peptide(PIIANP) is…
Abstract Number: 2025 • 2015 ACR/ARHP Annual Meeting
Modification of Structural Lesions on Magnetic Resonance Imaging By Etanercept: A 12-Week Randomized Placebo-Controlled Trial
Walter Maksymowych¹, Stephanie Wichuk², Maxime Dougados³, Heather Jones⁴, Annette Szumski⁵, Lisa Marshall⁴, Jack F Bukowski⁶ and Robert G Lambert⁷, ¹Department of Medicine, University of Alberta, Edmonton, AB, Canada, ²Rheumatology Research Lab, University of Alberta, Edmonton, AB, Canada, ³Rheumatology Department, Hôpital Cochin, Paris, France, ⁴Inflammation Global Medical Affairs, Pfizer, Collegeville, PA, ⁵Department of Biostatistics, Pfizer, Collegeville, PA, ⁶Clinical Affairs, Pfizer, Collegeville, PA, ⁷Department of Radiology & Diagnostic Imaging, University of Alberta, Edmonton, AB, Canada
Background/Purpose: Modification of structural lesions by anti-TNF therapy has not been demonstrated in a randomized placebo (PBO)-controlled trial. The Spondyloarthritis Research Consortium of Canada (SPARCC)…
Abstract Number: 315 • 2015 ACR/ARHP Annual Meeting
Structural Effects of Sprifermin in Knee Osteoarthritis: A Post-Hoc Analysis on Cartilage and Non-Cartilaginous Tissue Alterations
Frank Roemer¹, Aida Aydemir², Stefan Lohmander³, Michel Crema⁴, Monica D. Marra⁵, Norma Muurahainen², Felix Eckstein⁶ and Ali Guermazi⁷, ¹Radiology, Boston University School of Medicine, Boston, MA, ²EMD Serono, Billerica, MA, ³Lund University, Lund, Sweden, ⁴Department of Radiology, Boston University School of Medicine, Boston, MA, ⁵Department of Radiology, BUSM, Boston, MA, ⁶Paracelsus Med Univ, Chondrometrics GmbH, Salzburg, Austria, ⁷Boston University School of Medicine, Boston, MA
Background/Purpose: A randomized, double-blind, placebo-controlled phase 1b clinical trial of sprifermin (rhFGF18) in knee OA assessed central medial tibio-femoral compartment cartilage thickness on quantitative MRI…
Abstract Number: 1310 • 2015 ACR/ARHP Annual Meeting
Efficacy of Abatacept in Patients with Rheumatoid Arthritis Assessed By MRI Scans of Bilateral Hands
Yuji Kukida¹, Akiko Kasahara¹, Takahiro Seno^1,2, Yu Isoda¹, Tomoya Sagawa¹, Takuya Inoue¹, Naoka Kamio¹, Risa Sagawa¹, Takashi Kida¹, Amane Nakabayashi¹, Hidetake Nagahara³, Ken Murakami¹, Aihiro Yamamoto¹, Satoshi Morita⁴, Hirotoshi Ito⁵, Masataka Kohno¹ and Yutaka Kawahito¹, ¹Inflammation and Immunology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan, ²Department of Rheumatic Diseases and Joint Function, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan, ³Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan, ⁴Department of Biomedical Statistics and Bioinformatics, Kyoto University Graduate School of Medicine, Kyoto, Japan, ⁵Department of Radiology, Kajiicho Medical Imaging Center, Kyoto, Japan
Background/Purpose: Previous radiographic and MRI studies have demonstrated that abatacept (ABT) can inhibit the progression of bone and joint destruction in patients with rheumatoid arthritis…
Abstract Number: 2030 • 2015 ACR/ARHP Annual Meeting
MRI Changes Associated with Neurological Compromise in Acute Pyogenic Vertebral Osteomyelitis: A Retrospective Study of 121 Patients
Géraldine Bart¹, Herve Redon², David Boutoille³, Olivier Hamel⁴, Yves Maugars¹ and Benoit Le Goff¹, ¹Rheumatology, Nantes University Hospital, Nantes, France, ²Nouvelles cliniques nantaises, Nantes, France, ³Infectious diseases, Nantes University Hospital, Nantes, France, ⁴Neurosurgery, Nantes University Hospital, Nantes, France
Background/Purpose: Vertebral osteomyelitis is a rare but potentially severe disease: previous works have estimated that neurological complications occurred in up to 59% cases. However, these works…
Abstract Number: 424 • 2015 ACR/ARHP Annual Meeting
Magnetic Resonance and Echocardiographic Strain Rate Imaging for the Early Detection of Cardiac Involvement in Juvenile Systemic Sclerosis
Francesco Zulian¹, Marta Balzarin¹ and Elena Reffo, Biagio Castaldi, Giorgia Martini, Alessandra Meneghel, Ornella Milanesi, ¹Department of Pediatrics, University of Padua, Padua, Italy
Background/Purpose: Cardiac involvement is one of the worst prognostic factors in JSSc. The diagnosis is usually based on clinical symptoms, EKG and conventional echocardiography, but…
Abstract Number: 1312 • 2015 ACR/ARHP Annual Meeting
Radiocarpal Cartilage Matrix Changes 3-Months after Anti-TNF Treatment for Rheumatoid Arthritis – Feasibility Study Using MR T1ρ� Imaging
Eric Ku¹, Valentina Pedoia², Matthew Tanaka³, Ursula Heilmeier¹, John Imboden⁴, Jonathan D. Graf⁵, Thomas M. Link⁶ and Xiaojuan Li⁷, ¹Department of Radiology & Biomedical Imaging, Musculoskeletal Quantitative Imaging Research, UCSF, San Francisco, CA, ²Department of Radiology & Biomedical Imaging, Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA, ³University of California Berkeley, Berkeley, CA, ⁴Rheumatology, Rheumatology, University of California San Francisco, San Francisco, CA, ⁵Rosalind Russell / Ephraim P. Engleman Rheumatology Research Center, University of California, San Francisco, San Francisco, CA, ⁶Department of Radiology and Biomedical Imaging, Musculoskeletal Quantitative Imaging Research, UCSF, San Francisco, CA, ⁷Radiology & Biomedical Imaging, Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA
Background/Purpose: Standard assessment of Rheumatoid Arthritis (RA) on MRI relies on semi-quantitative joint space narrowing scores that are not sensitive to cartilage focal lesions or…
Abstract Number: 2093 • 2015 ACR/ARHP Annual Meeting
Are General and Central Adiposity Associated with MRI-Assessed Structural Changes in the Knees of Older Adults?
Tomoko Fujii¹, Iva Miljkovic¹, Robert M. Boudreau², Ali Guermazi³, Sara R. Piva⁴, Elsa S. Strotmeyer², Laura Carbone⁵, Tamara B. Harris⁶, Elisa A. Marques⁶, M Kyla Shea⁷, Michael C. Nevitt⁸, Anne B. Newman² and C Kent Kwoh⁹, ¹University of Pittsburgh, Pittsburgh, PA, ²Epidemiology, University of Pittsburgh, Pittsburgh, PA, ³Department of Radiology, Boston University School of Medicine, Boston, MA, ⁴Physical Therapy, University of Pittsburgh, Pittsburgh, PA, ⁵Rheumatology, Georgia Regents University, Augusta, GA, ⁶National Institute on Aging, Bethesda, MD, ⁷Tuffs University, Boston, MA, ⁸Epidemiology and Biostatistics, UCSF, San Francisco, CA, ⁹University of Arizona, Tucson, AZ
Background/Purpose: Obesity is one of the few modifiable risk factors of knee osteoarthritis (OA). However, it is not established whether a mechanical or metabolic mechanism…
Abstract Number: 465 • 2015 ACR/ARHP Annual Meeting
MRI Bone Erosion at Baseline Predicts the Subsequent Radiographic Progression in Early-Stage RA Patients Who Achieved in Sustained Clinical Good Response: Sub-Analysis from Nagasaki University Early Arthritis Cohort
Mami Tamai¹, Yoshikazu Nakashima¹, Kazuhiko Arima², Junko Kita¹, Masataka Umeda¹, Shoichi Fukui¹, Ayako Nishino¹, Takahisa Suzuki¹, Yoshiro Horai¹, Akitomo Okada³, Tomohiro Koga¹, Shin-ya Kawashiri^1,2, Naoki Iwamoto¹, Kunihiro Ichinose¹, Satoshi Yamasaki⁴, Hideki Nakamura¹, Tomoki Origuchi⁵, Kiyoshi Aoyagi², Masataka Uetani⁶, Katsumi Eguchi⁷ and Atsushi Kawakami¹, ¹Department of Immunology and Rheumatology, Nagasaki University, Nagasaki, Japan, ²Department of Public Health, Nagasaki University, Nagasaki, Japan, ³Japanese Red Cross Nagasaki Genbaku Hospital, Nagasaki, Japan, ⁴Hiroshima University, Hiroshima, Japan, ⁵Department of Rehabilitation Sciences, Nagasaki University, Nagasaki, Japan, ⁶Department of Radiology and Radiation Research, Nagasaki University, Nagasaki, Japan, ⁷Department of Rheumatology, Sasebo Chuo Hospital, Sasebo, Japan
Background/Purpose: Given the improved detection of joint injury by MRI than by clinical examination, EULAR recommendations for the use of imaging of the joints in…
Abstract Number: 1314 • 2015 ACR/ARHP Annual Meeting
Quantitative MRI Measurement of Tenosynovitis Demonstrates Differing Responses of Synovitis and Tenosynovitis after RA Treatment
Michael A. Bowes¹, Gwenael Guillard¹, Graham R. Vincent², Jane E. Freeston³, Edward M. Vital⁴, Paul Emery⁵ and Philip G. Conaghan⁶, ¹Imorphics, Manchester, United Kingdom, ²Imorphics Ltd, Manchester, United Kingdom, ³LIMM Section of Musculoskeletal Disease, University of Leeds, Leeds, United Kingdom, ⁴Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, ⁵Leeds Institute of Rheumatic and Musculoskeletal Medicine, Leeds Gen Infirmary, Leeds, United Kingdom, ⁶University of Leeds & NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds, United Kingdom
Background/Purpose: Inflammation of the tendon sheaths (tenosynovitis) is a recognised component of rheumatoid arthritis (RA). A comprehensive assessment of inflammation will require the inclusion of…
Abstract Number: 2119 • 2015 ACR/ARHP Annual Meeting
Findings and Therapeutic Impact of Magnetic Resonance Imaging (MRI) Studies for Patients with Lower Back Pain with Neurologic Symptoms. Are We Choosing Wisely?
Patrick Nguyen¹, Nathalie Carrier² and Ariel Masetto³, ¹Internal Medicine, Université de Sherbrooke, Sherbrooke, QC, Canada, ²Division of Rheumatology, Université de Sherbrooke, Sherbrooke, QC, Canada, ³Rheumatology, Université de Sherbrooke, Sherbrooke, QC, Canada
Background/Purpose: According to different guidelines, the presence of neurological symptoms in patients with lower back pain (LBP) is a validated indication for more complex imaging…

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