Abstracts tagged "MRI"

Abstract Number: 1776 • 2016 ACR/ARHP Annual Meeting
Analysis of Progressive Brain and Corpus Callosum Atrophy and Association with Th1 and Th2 Cytokines in Systemic Lupus Erythematosus
Mariana Postal¹, Aline Tamires Lapa¹, Karina O. Peliçari¹, Nailu A. Sinicato², Fernando A. Peres¹, Wesley Geraldo Ferreira³, Lilian TL Costallat³, Fernando Cendes³ and Simone Appenzeller⁴, ¹Medicine, State University of Campinas, Campinas, Brazil, ²Pediatrics, State University of Campinas, Campinas, Brazil, ³State University of Campinas, Campinas, Brazil, ⁴Division of Rheumatology, Faculty of Medical Science, State University of Campinas, São Paulo, Brazil
Background/Purpose: The pathophysiology of brain damage SLE is complex. The aim of this study was to determine brain atrophy progression and the association with Th1…
Abstract Number: 936 • 2016 ACR/ARHP Annual Meeting
Reliability and Responsiveness of an Omeract Tenosynovitis Magnetic Resonance Imaging Scoring System for the Rheumatoid Arthritis Wrist and Hand
Daniel Glinatsi¹, Paul Bird², Frédérique Gandjbakhch^3,4, Espen A. Haavardsholm⁵, Philip G. Conaghan⁶ and Mikkel Østergaard⁷, ¹Center for Rheumatology and Spine Diseases, Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen, Denmark, Glostrup, Denmark, ²Medicine, University of New South Wales, Sydney, NSW, Australia, ³Service de Rhumatologie, GH Pitié-Salpétrière, MD, Paris, France, ⁴Department of Rheumatology, APHP, Pitié Salpétrière Hospital, Universite Paris 6, Paris, France, ⁵Dept. of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, ⁶Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, ⁷Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Denmark, Copenhagen, Denmark
Background/Purpose: Tenosynovitis in the hand occurs frequently and early in rheumatoid arthritis (RA) and sensitive outcome measures are important to assess and monitor the inflammatory…
Abstract Number: 1788 • 2016 ACR/ARHP Annual Meeting
Alterations in Sense of Smell and Limbic Structures in Patients with Systemic Lupus Erythematosus during 3-Years Follow-up
Fernando A. Peres¹, Karina de Oliveira Peliçari¹, Mariana Postal¹, Nailu A. Sinicato², Leticia Rittner³, Lilian Tereza Costallat⁴ and Simone Appenzeller⁵, ¹Medicine, State University of Campinas, Campinas, Brazil, ²Pediatrics, State University of Campinas, Campinas, Brazil, ³UNICAMP, Sao Paulo, Brazil, ⁴RUA EZEQUIEL MAGALHAES,26, Unicamp, Campinas, Brazil, ⁵Pediatric Rheumatology Unit, State University of Campinas, Campinas, Brazil
Background/Purpose: Many neurologic and neurodegenerative abnormalities are first demonstrable in the olfactory system with loss of smell up to 10 years before the onset of…
Abstract Number: 50 • 2016 ACR/ARHP Annual Meeting
Tai Chi Significantly Modulates Resting State Functional Connectivity of the Cognitive Control Network in Fibromyalgia
Jian Kong¹, Kristen Jorgenson², zengjian wang², Emily Wolcott³, William F. Harvey⁴ and Chenchen Wang⁴, ¹Massachusetts General Hospital, Boston, MA, ²MGH, Boston, MA, ³Tufts Medical Center, Boston, MA, ⁴Rheumatology, Tufts Medical Center, Boston, MA
Background/Purpose: Fibromyalgia (FM) is a common and complex musculoskeletal pain syndrome with unsatisfactory treatment options. Studies suggest that Tai Chi mind-body exercise may be…
Abstract Number: 945 • 2016 ACR/ARHP Annual Meeting
When and Where Musculoskeletal Ultrasound Might Replace Magnetic Resonance in the Assessment of Patients with Juvenile Idiopathic Arthritis?
Stefano Lanni¹, Francesca Magnaguagno², Erica Ricci³, Angela Pistorio⁴, Cecilia Bava¹, Alberto Martini⁵ and Clara Malattia⁶, ¹Pediatria 2 Reumatologia, Istituto Giannina Gaslini, Genoa, Italy, ²UO Radiologia, Istituto Giannina Gaslini, Genoa, Italy, ³Istituto G. Gaslini, Pediatria 2 -Reumatologia, genova, Italy, ⁴Pediatria II, Reumatologia, PRINTO, Istituto Giannina Gaslini, Genoa, Italy, ⁵PRINTO-IRCCS, Genova, Italy, ⁶Pediatria2 Reumatologia, Istituto Giannina Gaslini, Genoa, Italy
Background/Purpose: Magnetic resonance imaging (MRI) is the most attractive imaging modality for the investigation of patients with juvenile arthritis (JIA). Musculoskeletal ultrasound (MSUS) has intuitive…
Abstract Number: 1870 • 2016 ACR/ARHP Annual Meeting
First Pilot Study of an Implantable Loop Recorder (ILR) in Systemic Sclerosis Detects Significant Cardiac Arrhythmias with CMR Abnormalities
Lesley-Anne Bissell¹, Bianca Dumitru¹, Giuseppina Abignano¹, Bara Erhayiem², Graham Fent², Peter Swoboda², Adam McDiarmid², John Greenwood², Francesco Del Galdo¹, Jacqueline Andrews¹, Sven Plein², Lee Graham² and Maya Buch¹, ¹Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds and NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom, ²Multidisciplinary Cardiovascular Research Centre & The Division of Cardiovascular and Diabetes Research, LIGHT, University of Leeds, Leeds, United Kingdom
Background/Purpose: SSc-cardiomyopathy associated conduction abnormalities carry a poor prognosis, but their pathogenesis is unclear. Early detection to prevent complications is essential. ILRs are well-established in…
Abstract Number: 151 • 2016 ACR/ARHP Annual Meeting
Distinct Phenotypes in Palindromic Rheumatism: Ultrasound and MRI during Palindromic Flares
Kulveer Mankia¹, Maria Antonietta D'Agostino¹, Laura Horton¹, Jackie L. Nam², Jane E. Freeston³, Andrew J. Grainger⁴ and Paul Emery⁵, ¹Rheumatology, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK, Leeds, United Kingdom, ²Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, ³NIHR Leeds Musculoskeletal Biomedical Research Unit, University of Leeds, Leeds, United Kingdom, ⁴U Leeds, Leeds, United Kingdom, ⁵NIHR-Leeds Musculoskeletal Biomedical Research Unit, Leeds, United Kingdom
Background/Purpose: Palindromic rheumatism (PR) is defined as a recurrent, self-abortive arthritis and/or para-arthritis, which progresses to RA in up to 50% patients (pts), particularly…
Abstract Number: 1017 • 2016 ACR/ARHP Annual Meeting
Statistical Simulation Using Data from the Foundation for the National Institute of Health/Osteoarthritis Initiative Biomarkers Consortium to Evaluate the Clinical Utility of Prognostic Knee Osteoarthritis Biomarkers in Designing a Knee Osteoarthritis Clinical Trial
Sheng Feng¹, Zheng (Roger) Liu², Feng Hong¹, Jeroen Medema¹, Rajesh Kamath¹ and Marc C. Levesque¹, ¹AbbVie Bioresearch Center, Worcester, MA, ²AbbVie Inc, AbbVie Bioresearch Center, Worcester, MA
Background/Purpose: Development of disease-modifying osteoarthritis drugs (DMOADs) for knee osteoarthritis (OA) has been challenging, partially owing to lack of prognostic biomarkers. Our objective was to…
Abstract Number: 2308 • 2016 ACR/ARHP Annual Meeting
Thigh Muscle MRI Reveals Extensive Muscle Edema and Early Fatty Replacement in Patients with Immune-Mediated Necrotizing Myopathy
Iago Pinal-Fernandez¹, Maria Casal-Dominguez², John A. Carrino³, Arash Lahoutiharahdashti², Pari Basharat⁴, Jemima Albayda², Julie J. Paik², Shivani Ahlawat⁵, Sonye K. Danoff⁶, Thomas E. Lloyd⁷, Andrew Mammen⁸ and Lisa Christopher-Stine⁶, ¹Muscle Diseases Unit, National Institute of Arthritis and Musculoskeletal and Skin Diseases. National Institutes of Health, Bethesda, MD, ²Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, ³Department of Radiology, Johns Hopkins University School of Medicine, Baltimore, MD, ⁴Rheumatology, University of Western Ontario, London, ON, Canada, ⁵Radiology, Johns Hopkins University School of Medicine, Baltimore, MD, ⁶Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, ⁷Neurology, Johns Hopkins, Baltimore, MD, ⁸National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD
Background/Purpose: The aim of this study was to define the pattern of muscle involvement in patients with immune-mediated necrotizing myopathy (IMNM). Methods: All Johns Hopkins…
Abstract Number: 169 • 2016 ACR/ARHP Annual Meeting
Ultrasound and Magnetic Resonance Imaging Fusion of Images and B-Flow Evaluation of Tenosynovitis – a Pilot Study on New Imaging Techniques in Rheumatoid Arthritis Patients
Mads Ammitzbøll-Danielsen^1,2, Daniel Glinatsi^2,3, Søren Torp-Pedersen⁴, Esperanza Naredo⁵, Mikkel Ostergaard² and Lene Terslev⁶, ¹Center for Rheumatology and Spine Diseases, Rigshospitalet - Glostrup, Copenhagen Center for Arthritis Research (COPECARE), Copenhagen, Denmark, ²Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark, ³Center for Rheumatology and Spine Diseases, Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen, Denmark, Glostrup, Denmark, ⁴Department of Diagnostics, Rigshospitalet, Glostrup, Copenhagen, Denmark, ⁵Rheumatology, Hospital General Universitario Gregorio Marañón and Universidad Complutense, Madrid, Spain, ⁶Center for Rheumatology and Spine Diseases, Rigshospitalet, Glostrup, Copenhagen Center for Arthritis Research (COPECARE), Copenhagen, Denmark
Background/Purpose: Image fusion is an advanced imaging technology, which enables fusion of ultrasound (US) and magnetic resonance imaging (MRI). This fusion gives for each…
Abstract Number: 1021 • 2016 ACR/ARHP Annual Meeting
Maintaining Sufficient Serum Vitamin D Levels over 2 Years Is Associated with Reduced Knee Structural and Symptomatic Changes in Patients with Knee Osteoarthritis
Shuang Zheng¹, Xingzhong Jin¹, Flavia M Cicuttini², Xia Wang¹, Zhaohua Zhu¹, Anita E Wluka³, Weiyu Han¹, Tania Winzenberg¹, Leigh Blizzard¹, Graeme Jones⁴ and Changhai Ding⁴, ¹Menzies Institute for Medical Research, University of Tasmania, Hobart, Australia, ²Monash University, Department of Epidemiology and Preventive Medicine, Melbourne, Australia, ³Australia, Armadale, Australia, ⁴Musculoskeletal Unit, Menzies Institute for Medical Research, University of Tasmania, Hobart, Australia
Background/Purpose: To examine whether those maintaining sufficient serum vitamin D levels have reduced knee structural changes and symptomatic improvement compared with those not maintaining sufficient…
Abstract Number: 2347 • 2016 ACR/ARHP Annual Meeting
Serum Levels of Resistin Are Associated with Synovial Inflammation and Knee Structural Changes in Patients with Symptomatic Knee Osteoarthritis
WEIYU HAN¹, Flavia M Cicuttini², Graeme Jones³ and Changhai Ding³, ¹Menzies Institute for Medical Research, University of Tasmania, Hobart, Australia, ²Monash University, Department of Epidemiology and Preventive Medicine, Melbourne, Australia, ³Musculoskeletal Unit, Menzies Institute for Medical Research, University of Tasmania, Hobart, Australia
Background/Purpose: Due to these sparse and inconsistent clinical data, our current study aims to describe the associations between serum levels of resistin, knee synovial inflammation…
Abstract Number: 302 • 2016 ACR/ARHP Annual Meeting
Long-Lasting Local Knee Structural Pathology Is Associated with Persistent Multi-Site Pain
Feng Pan¹, Jing Tian², Dawn Aitken³, Flavia M Cicuttini⁴, Changhai Ding³ and Graeme Jones³, ¹Musculoskeletal Unit, Menzies Institute for Medical Research, University of Tasmania, Hobart,7000, Australia, ²Public health unit, Menzies Institute for Medical Research, University of Tasmania, Hobart, Australia, ³Musculoskeletal Unit, Menzies Institute for Medical Research, University of Tasmania, Hobart, Australia, ⁴Monash University, Department of Epidemiology and Preventive Medicine, Melbourne, Australia
Background/Purpose: Knee pain is the most common manifestation of knee osteoarthritis (OA) and typically accompanied by pain at other sites. Knee structural pathology in MRI,…
Abstract Number: 1044 • 2016 ACR/ARHP Annual Meeting
Treatment with Tofacitinib Is Associated with Clinically Meaningful Reductions in Axial MRI Inflammation in Patients with Ankylosing Spondylitis
Walter Maksymowych¹, Désirée van der Heijde², Xenofon Baraliakos³, Atul A. Deodhar⁴, Matt Brown⁵, Sarah Sherlock⁶, David Li⁷, Dona Fleishaker⁸ and Thijs Hendrikx⁷, ¹Department of Medicine, University of Alberta, Edmonton, AB, Canada, ²Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ³Rheumazentrum Ruhrgebiet, Herne, Germany, ⁴Division of Arthritis and Rheumatic Diseases, Oregon Health and Science University, Portland, OR, ⁵Institute for Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Australia, ⁶Pfizer Inc, Cambridge, MA, ⁷Pfizer Inc, Collegeville, PA, ⁸Pfizer Inc, Groton, CT
Background/Purpose: Tofacitinib is an oral Janus kinase inhibitor. Minimum clinically important differences (MCID) for SPondyloArthritis Research Consortium of Canada (SPARCC) MRI SI joint and spine…
Abstract Number: 2484 • 2016 ACR/ARHP Annual Meeting
Real World Treat to Target Strategy in Rheumatoid Arthritis: Radiograph and MRI Outcomes in Three Cohorts with 18 Month Follow up
Paul Bird¹, Maureen Rischmueller², Marie Feletar³, Gail Grant⁴, Margaret P. Staples⁵ and Stephen Hall⁶, ¹Medicine, University of New South Wales, Sydney, NSW, Australia, ²Rheumatology, The Queen Elizabeth Hospital, Adelaide, Australia, ³Department of Epidemiology and Preventive Medicine, Monash University, Dandenong, Australia, ⁴Emeritus Research, Malvern East, Australia, ⁵Monash Department of Clinical Epidemiology, Cabrini Institute and Monash University, Malvern, Australia, ⁶Cabrini Health and Monash University, Melbourne, VIC, Australia
Background/Purpose: The Treat to Target (TTT) model is well established in the treatment of rheumatic disease. Achieving DAS remission is one of the primary goals…

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