ACR Meeting Abstracts

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Abstracts tagged "MRI"

  • Abstract Number: 302 • 2016 ACR/ARHP Annual Meeting

    Long-Lasting Local Knee Structural Pathology Is Associated with Persistent Multi-Site Pain

    Feng Pan1, Jing Tian2, Dawn Aitken3, Flavia M Cicuttini4, Changhai Ding3 and Graeme Jones3, 1Musculoskeletal Unit, Menzies Institute for Medical Research, University of Tasmania, Hobart,7000, Australia, 2Public health unit, Menzies Institute for Medical Research, University of Tasmania, Hobart, Australia, 3Musculoskeletal Unit, Menzies Institute for Medical Research, University of Tasmania, Hobart, Australia, 4Monash University, Department of Epidemiology and Preventive Medicine, Melbourne, Australia

    Background/Purpose:  Knee pain is the most common manifestation of knee osteoarthritis (OA) and typically accompanied by pain at other sites. Knee structural pathology in MRI,…
  • Abstract Number: 1044 • 2016 ACR/ARHP Annual Meeting

    Treatment with Tofacitinib Is Associated with Clinically Meaningful Reductions in Axial MRI Inflammation in Patients with Ankylosing Spondylitis

    Walter Maksymowych1, Désirée van der Heijde2, Xenofon Baraliakos3, Atul A. Deodhar4, Matt Brown5, Sarah Sherlock6, David Li7, Dona Fleishaker8 and Thijs Hendrikx7, 1Department of Medicine, University of Alberta, Edmonton, AB, Canada, 2Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 3Rheumazentrum Ruhrgebiet, Herne, Germany, 4Division of Arthritis and Rheumatic Diseases, Oregon Health and Science University, Portland, OR, 5Institute for Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Australia, 6Pfizer Inc, Cambridge, MA, 7Pfizer Inc, Collegeville, PA, 8Pfizer Inc, Groton, CT

    Background/Purpose: Tofacitinib is an oral Janus kinase inhibitor. Minimum clinically important differences (MCID) for SPondyloArthritis Research Consortium of Canada (SPARCC) MRI SI joint and spine…
  • Abstract Number: 2484 • 2016 ACR/ARHP Annual Meeting

    Real World Treat to Target Strategy in Rheumatoid Arthritis: Radiograph and MRI Outcomes in Three Cohorts with 18 Month Follow up

    Paul Bird1, Maureen Rischmueller2, Marie Feletar3, Gail Grant4, Margaret P. Staples5 and Stephen Hall6, 1Medicine, University of New South Wales, Sydney, NSW, Australia, 2Rheumatology, The Queen Elizabeth Hospital, Adelaide, Australia, 3Department of Epidemiology and Preventive Medicine, Monash University, Dandenong, Australia, 4Emeritus Research, Malvern East, Australia, 5Monash Department of Clinical Epidemiology, Cabrini Institute and Monash University, Malvern, Australia, 6Cabrini Health and Monash University, Melbourne, VIC, Australia

    Background/Purpose: The Treat to Target (TTT) model is well established in the treatment of rheumatic disease. Achieving DAS remission is one of the primary goals…
  • Abstract Number: 306 • 2016 ACR/ARHP Annual Meeting

    MRI-Detected Cartilage Damage, Meniscal Damage, and Meniscal Extrusion Prior to Incident Radiographic Osteoarthritis and the Subsequent Trajectory of Joint Space Loss

    C. Kent Kwoh1, Frank Roemer2,3, Erin L. Ashbeck4, Charles Ratzlaff4, Jeffrey Duryea5 and Ali Guermazi6, 11501 N. Campbell Avenue, Room 8303, The University of Arizona Arthritis Center, Tucson, AZ, 2Department of Radiology, Boston University School of Medicine, Boston, MA, 3Radiology, University of Erlangen, Erlangen, Germany, 4The University of Arizona Arthritis Center, Tucson, AZ, 5Radiology, Brigham & Women's Hospital/ Harvard Medical School, Boston, MA, 6Boston University School of Medicine, Boston, MA

    Background/Purpose: Loss of joint space width (JSW) on x-ray is the recommended standard to define osteoarthritis progression. However, both cartilage and meniscal damage contribute to…
  • Abstract Number: 1293 • 2016 ACR/ARHP Annual Meeting

    Utility of Extremity Magnetic Resonance Imaging (eMRI) without Contrast Enhancement in Detecting Preclinical Psoriatic Arthritis

    Ashish J Mathew1, Jyoti Panwar2, Paul Bird3, Renu George4 and Debashish Danda1, 1Clinical Immunology & Rheumatology, Christian Medical College, Vellore, India, Vellore, India, 2Christian Medical College, Vellore, India, Vellore, India, 3University of New South Wales, Sydney, Australia, Sydney, NSW, Australia, 4Dermatology, Christian Medical College, Vellore, India, Vellore, India

    Background/Purpose: Between 8-39% of patients with cutaneous psoriasis may develop psoriatic arthritis (PsA). Subclinical inflammatory joint disease in patients with psoriasis is common. i,ii This study…
  • Abstract Number: 2690 • 2016 ACR/ARHP Annual Meeting

    Detection of Dorsal Root Ganglionitis with Magnetic Resonance Neurography in Sensory Ataxic Neuropathy Associated with SjöGren’s Syndrome

    Takeshi Yoshida1, Takeshi Sueyoshi2, Shugo Suwazono3 and Mitsuyo Kinjo4,5, 1Internal Medicine, Okinawa Chubu Hospital, Uruma, Japan, 2Radiology, Minei Daiichi Hospital, Urasoe, Japan, 3Brain-Nerve-Muscle Research Center, National Hospital Organization Okinawa Hospital, Uruma, Japan, 4Rheumatology, Okinawa Chubu Hospital, Uruma, Japan, 5Internal Medicine, Okinawa Chubu Hospital, Uruma City Okinawa, Japan

    Background/Purpose: Sensory ataxic neuropathy (SAN) is one of the neurologic complications in Sjögrenfs syndrome (SS). The underlying pathology was lymphocytic infiltration to the dorsal root…
  • Abstract Number: 315 • 2016 ACR/ARHP Annual Meeting

    Hip Inflammation MRI Scoring System (HIMRISS) to Predict Response to Hyaluronic Acid (HAnox-M-XL) Injection in Hip Osteoarthritis

    Nicolas Deseyne1, Damien Loeuille2, Thierry Conrozier3, Ulrich Weber4, Jacob Jaremko5, Henri Lellouche6, Bernard Maillet7, Joel Paschke8, Jonathan Epstein9 and Walter P. Maksymowych10, 1Department of Rheumatology, CHRU Vandoeuvre les Nancy,, Vandoeuvre, France, 2Rheumatology, CHRU Nancy, Vandoeuvre les Nancy, France, 3Department of Rheumatology, North Hospital Franche-Comté, Belfort, France, 4Department of Research, King Christian 10th Hospital for Rheumatic Diseases, Graasten, Denmark, 5Radiology, Radiology, University of Alberta, Edmonton, AB, Canada, 6Department of Rheumatology, Lariboisière Hospital, Paris, France, Paris, France, 7Department of Rheumatology, Clinique Saint Odilon, Moulins, France, Moulins, France, 8CaRE Arthritis, Edmonton, AB, Canada, 9CEC-Inserm CIE6, Epidemiology and Clinical Evaluations Department, CHRU Vandoeuvre les Nancy, France, Vandoeuvre Les Nancy, France, 10Medicine, University of Alberta, Edmonton, AB, Canada

    Background/Purpose:  To assess predictors of response, according to hip MRI inflammatory scoring system (HIMRISS), in a sample of patients with hip osteoarthritis (OA) treated by…
  • Abstract Number: 1294 • 2016 ACR/ARHP Annual Meeting

    Oblique Views Radiographs Have Advantages over Antero-Posterior View Radiographs in Assessing Sacroiliitis in Patients with Early Axial Spondyloarthritis

    Zaiying Hu1, Shanglin Zhu2, Zetao Liao3, Baiyu Zhang2 and Jieruo Gu4, 1Department of Rheumatology, Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China, 2Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, China, 3Rheumatology, 3rd Affiliated Hoapital of Sun Yat-Sen Uni, Guangzhou, China, 4Rheumatology, third affiliated hospital of Sun Yat-sen Universtiy, Guangzhou, China

    Background/Purpose:  All patients fulfilled the 2009 ASAS classification criteria for axial SpA. Three readers blinded (two radiologists and one rheumatologist) investigated the A-P view and…
  • Abstract Number: 3004 • 2016 ACR/ARHP Annual Meeting

    The Choosing Wisely Initiative: Is It Complete?

    Navya Kuchipudi and Cathie-Ann Mancuso, Internal Medicine, Saint Peters University Hospital, New Brunswick, NJ

    Background/Purpose: Low back pain is a highly prevalent problem affecting approximately 70-85% of Americans in their lifetime (1). American College of Physicians (ACP) has recommended…
  • Abstract Number: 538 • 2016 ACR/ARHP Annual Meeting

    What Is the Relationship Between Early Metacarpophalangeal Erosions on MRI and Joint Pain in Rheumatoid Arthritis?

    Matthew A. Jessome1, Karen A. Beattie2, William G. Bensen2, Raja S. Bobba2, Alfred Cividino2, Patrick D. Emond2, Chris Gordon2, Lawrence Hart2, George Ioannidis2, Maggie Larche2, Arthur Lau3, Ruben Tavares2, Stephen Tytus2 and Jonathan D. Adachi2, 1Faculty of Health Sciences, McMaster University, Hamilton, ON, Canada, 2St Joseph's Healthcare Hamilton, Hamilton, ON, Canada, 350 Charlton Avenue East, St Joseph's Healthcare Hamilton, Hamilton, ON, Canada

    Background/Purpose: Erosive damage to small joints is a hallmark feature of rheumatoid arthritis (RA). The degree to which early erosive damage contributes to joint pain…
  • Abstract Number: 1298 • 2016 ACR/ARHP Annual Meeting

    Development and Validation of Berlin and Sparcc MRI Sacroiliac Joint Scoring Methods for the Semi-Axial Scan Plan

    Pernille Hededal1, Mikkel Østergaard2, Inge Juul Sorensen3, Anne Gitte Loft4, Jens Hindrup3, Gorm Thamborg3, Karsten Asmussen3, Oliver Hendricks5, Jesper Nørregaard3, Jakob M. Møller6, Anne Grethe Jurik7, Lone Morsel-Carlsen1, Lone Balding8 and Susanne Juhl Pedersen3, 1Department of Radiology, Rigshospitalet, Copenhagen, Denmark, 2Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Denmark, Copenhagen, Denmark, 3Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen, Denmark, 4Departments of Rheumatology at Vejle and Aarhus Hospitals, Vejle and Aarhus, Denmark, 5Dep. of Rheumatology, King Christians Hospital for Rheumatic Diseases, Copenhagen, Denmark, 6Department of Radiology, Copenhagen University Hospital Herlev and Gentofte, Herlev, Denmark, 7Dept. of Radiology, Aarhus University Hospital, Aarhus, Denmark, 8Department of Radiology, Copenhagen University Hospital Herlev and Gentofte, Copenhagen, Denmark

    Background/Purpose: In clinical trials encompassing axial spondyloarthritis (axSpA) patients, bone marrow edema (BME) in the sacroiliac joints (SIJs) is assessed with standardized and validated semi-quantitative…
  • Abstract Number: 3183 • 2016 ACR/ARHP Annual Meeting

    Tocilizumab for the Treatment of Giant Cell Arteritis – MR-Angiography Results from the First Randomized Placebo-Controlled Trial 

    Stephan Reichenbach1,2, Sabine Adler3, Jennifer Cullmann4, Harald Bonel4, Stefan Kuchen5, Felix Wermelinger1, Diana Dan1, Michael Seitz1 and Peter M. Villiger1, 1Department of Rheumatology, Immunology and Allergology, University Hospital Bern, Bern, Switzerland, 2Institute of Social and Preventive Medicine, University of Bern, Bern, Switzerland, 3Rheumatology, Immunology, Allergology, University Hospital Bern, Bern, Switzerland, 4Department of Diagnostic, Interventional and Pediatric Radiology, University Hospital Bern, Bern, Switzerland, 5Rheumatology, Immunology, and Allergology, University of Bern, Bern, MD, Switzerland

    Background/Purpose:  As published in The Lancet online, March 4, 2016, the first randomized, placebo-controlled trial (RCT) of tocilizumab (TCZ) in giant cell arteritis (GCA) showed…
  • Abstract Number: 579 • 2016 ACR/ARHP Annual Meeting

    MRI-Detected Osteitis Is Not Associated with the Presence or Level of ACPA Alone, but with the Combined Presence of ACPA and RF

    Debbie M. Boeters1, Wouter P. Nieuwenhuis1, Marije K. Verheul1, Elize C. Newsum1, Monique Reijnierse2, René E.M. Toes1, Leendert A. Trouw1 and Annette H.M. van der Helm-van Mil1, 1Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 2Department of Radiology, Leiden University Medical Center, Leiden, Netherlands

    Background/Purpose: Within rheumatoid arthritis (RA) bone marrow edema (BME, osteitis) and anti-citrullinated protein antibodies (ACPAs) are associated with radiographic progression. ACPA has been associated with…
  • Abstract Number: 1300 • 2016 ACR/ARHP Annual Meeting

    MRI-Detected Inflammation Is Associated with Functional Disability in Early Arthritis – Results of a Cross-Sectional Study

    Leonie E Burgers1, Wouter P Nieuwenhuis1, Hanna W van Steenbergen1, Elize C Newsum1, Tom WJ Huizinga1, Monique Reijnierse2, Saskia le Cessie3 and Annette HM van der Helm-van Mil1, 1Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 2Department of Radiology, Leiden University Medical Center, Leiden, Netherlands, 3Medical statistics and Epidemiology, Department of Medical Statistics and Epidemiology, Leiden University Medical Center, Leiden, Netherlands

    Background/Purpose:  Magnetic resonance imaging (MRI) sensitively detects inflammation, but the clinical relevance of MRI-detected inflammation is undetermined in early arthritis. Therefore, this cross-sectional study investigated…
  • Abstract Number: 3210 • 2016 ACR/ARHP Annual Meeting

    10+ Years’ Follow-up of a Danish 2-Year Treat-to-Target RCT in Patients with Early Rheumatoid Arthritis: Baseline Predictors of Functional and Radiographic Outcomes

    Merete Lund Hetland1, Kristian Stengaard-Pedersen2, Peter Junker1, Hanne Lindegaard1, Torkell Ellingsen1, Jan Pødenphant2, Henrik Skjødt1, Aage Vestergaard2, Bo Jannik Ejbjerg1, Søren Jacobsen1, Niels Steen Krogh1, Mikkel Ostergaard1 and Kim Hørslev-Petersen2, 1Rigshospitalet (Glostrup and Blegdamsvej), Århus University Hospital, Odense University Hospital, Herlev/Gentofte Hospital, Slagelse Sygehus, Chr X hospital (University of South Denmark) and Zitelab Aps, DANBIO Registry and Departments of Rheumatology, Glostrup, Denmark, 2Rigshospitalet (Glostrup and Blegdamsvej), Århus University Hospital, Odense University Hospital, Herlev/Gentofte Hospital, Slagelse Sygehus, Chr X hospital (University of South Denmark) and Zitelab Aps, DANBIO Registry and Departments of Rheumatology, Copenhagen, Denmark

    Background/Purpose:  Few RCTs have investigated long-term (10+ years) outcomes of goal-directed synovitis suppression in early rheumatoid arthritis (RA). The CIMESTRA trial was a 2-year double-blinded…
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