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Abstracts tagged "MRI"

  • Abstract Number: 1301 • 2016 ACR/ARHP Annual Meeting

    Analysis of Anatomical Sites Causing Dactylitis and Their Responsiveness to Change Under TNF-Therapy in Psoriatic Arthritis By High Resolution MRI

    Dr. Philipp Sewerin, PD Dr. Stefan Vordenbäumen, Dr. Ruben Sengewein, Prof. Dr. Matthias Schneider and Prof. Dr. Benedikt Ostendorf, Department of Rheumatology & Hiller Research Unit, Heinrich-Heine University, Düsseldorf, Germany

    Background/Purpose: Results:  The following sites were most commonly involved in dactylitis: collateral ligament enthesitis 11/12 (92%); extensor tendons enthesitis 5/12 (42%); flexor tenosynovitis 9/12 (75%),…
  • Abstract Number: 678 • 2016 ACR/ARHP Annual Meeting

    Additional Information from CT or MRI Imaging Can Increase Rheumatologists’ Consensus on Grading Sacroiliitis By Radiography: Results of the Trimage Project

    Nigil Haroon1, Xenofon Baraliakos2, Anne Grethe Jurik3, Gercek Can4, Ali Balcı5, Muhammet Cinar6, Ediz Dalkilic7, Salim Donmez8, Omer Nuri Pamuk9, Yavuz Pehlivan10, Salih Pay11, Handan Yarkan12, Gokce Kenar13 and Nurullah Akkoc13, 1Rheumatology, Toronto Western Hospital, University of Toronto, Spondylitis Clinic, Toronto, ON, Canada, 2Rheumazentrum Ruhrgebiet Herne, Ruhr-University Bochum, Herne, Germany, 3Department of Radiology, Aarhus University Hospital, Aarhus, Denmark, 4Department of Rheumatology, Dokuz Eylul University Faculty of Medicine, Izmir, Turkey, 5Radiology, Dokuz Eylul University, Izmir, Turkey, 6Division of Rheumatology, Gülhane Military Medical Academy, School of Medicine, Ankara, Turkey, 7Department of Rhematology, Uludag University Faculty of Medicine, Bursa, Turkey, 8Department of Rheumatology, Trakya University Faculty of Medicine, Edirne, Turkey, 9Rheumatology, Trakya University Faculty of Medicine, Edirne, Turkey, 10Rheumatology, Uludag University Medcal Faculty, Bursa, Turkey, 11Rheumatology, Yüksek Ihtisas University, Special Koru Hospital, Ankara, Turkey, 12Rheumatology, Dokuz Eylul University Faculty of Medicine, İzmir, Turkey, 13Rheumatology, Dokuz Eylul University Faculty of Medicine, Izmir, Turkey

    Background/Purpose:  The diagnosis of ankylosing spondylitis (AS) is anchored on definitive changes of sacroiliits by radiography. This is relevant not only to clinical diagnosis, but…
  • Abstract Number: 1302 • 2016 ACR/ARHP Annual Meeting

    Silent Progression in Patients with Rheumatoid Arthritis: Is DAS28 Remission an Insufficient Goal in RA? Results from the German Remission-PLUS Cohort

    Dr. Philipp Sewerin1, PD Dr. Stefan Vordenbäumen1, Annika Hoyer2, Ralph Brinks1, Dr. Christian Buchbender3, Dr. Christoph Schleich4, Sabine Kamp1, Prof. Dr. Gerald Antoch3, Prof. Dr. Matthias Schneider1 and Prof. Dr. Benedikt Ostendorf1, 1Department of Rheumatology & Hiller Research Unit, Heinrich-Heine University, Düsseldorf, Germany, 2Institute for Biometry and Epidemiology, German Diabetes Center, Duesseldorf, Germany, 3Diagnostic and Interventional Radiology, Heinrich-Heine-University, Düsseldorf, Germany, 4Dep. for diagnostic and interventional Radiology, Heinrich-Heine-University, Duesseldorf, Germany

    Background/Purpose: disease activity score in 28 joints; Methods: Data-sets of 80 RA patients from the REMISSION-plus study cohort who fulfilled the following criteria were retrospectively…
  • Abstract Number: 688 • 2016 ACR/ARHP Annual Meeting

    Spondyloarthritis Research Consortium of Canada (SPARCC) Baseline MRI SI Joint Score ≥2 Better Predicts Response to Golimumab Than Does Assessment of Spondyloarthritis International Society (ASAS) MRI Positivity in Nonradiographic Axial Spondyloarthritis

    Walter Maksymowych1, Anjela Tzontcheva2, George Philip2, Gina Bergman2, Susan Huyck2 and Sean P. Curtis2, 1Medicine, University of Alberta, Edmonton, AB, Canada, 2Merck & Co., Inc., Kenilworth, NJ

    Background/Purpose: Golimumab (GLM) was shown to be effective for nonradiographic axial spondyloarthritis (nr-axSpA) in a randomized, double-blind, placebo-controlled, phase 3 study (GO-AHEAD; NCT01453725).1 The SPondyloArthritis…
  • Abstract Number: 1303 • 2016 ACR/ARHP Annual Meeting

    Extended T2-Times in Cardiovascular Magnetic Resonance (CMR) in Patients with Systemic Lupus Erythematosus (SLE) and Persisted Dyspnoea: Is SLE-Associated Myocarditis an Underestimated Problem?

    Dr. Philipp Sewerin1, Vera Lachmann2, Mareike Gastl2, Patrick Behm3, PD Dr. Rebecca Fischer-Betz4, Prof. Dr. Benedikt Ostendorf1, Dr. Gamal Chehab5, Prof. Dr. Matthias Schneider1, Prof. Dr. Malte Kelm2 and Dr. Florian Bönner2, 1Department of Rheumatology & Hiller Research Unit, Heinrich-Heine University, Düsseldorf, Germany, 2Department of Internal Medicine, Division of Cardiology, Pulmology and Vascular Medicine and Molecular Cardiology, Heinrich-Heine University, Düsseldorf, Germany, 3Heinrich-Heine University, Düsseldorf, Germany, 4Department of Rheumatology & Hiller Research Unit, Heinrich-Heine-University, Duesseldorf, Germany, 5Department of Rheumatology & Hiller Research Unit, Heinrich-Heine University, 40225 Duesseldorf, Germany

    Background/Purpose: To investigate the value of cardiovascular magnetic resonance (CMR) and T2-mapping in patients with systemic lupus erythematosus (SLE) and persistent dyspnoea without sings for…
  • Abstract Number: 697 • 2016 ACR/ARHP Annual Meeting

    Does Axial Spondyloarthritis Phenotype Correlate with Imaging Morphotype?

    Xenofon Baraliakos1, Annette Szumski2, Heather Jones3 and Lianne S. Gensler4, 1Rheumazentrum, Ruhr University, Bochum, Germany, 2inVentiv Health, Princeton, NJ, 3Inflammation & Immunology, Pfizer, Collegeville, PA, 4Medicine/Rheumatology, University of California, San Francisco, San Francisco, CA

    Background/Purpose: Traditionally, radiographic imaging was used to describe morphological differences between various types of axial SpA (axSpA). MRI has advanced understanding of disease, enabled earlier…
  • Abstract Number: 1304 • 2016 ACR/ARHP Annual Meeting

    2D and 3D Measurements of Osteoarthritis Joint Space Width Have Good Agreement in Radiographically Normal Knees but Poor Agreement with Advancing Kellgren-Lawrence Grade: Data from the Osteoarthritis Initiative

    Aaron Ray1, Michael A Bowes2, Bright Dube1, Elizabeth M.A. Hensor1, Andrew J Barr1 and Philip G. Conaghan1, 1Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, 2Imorphics Ltd, Manchester, United Kingdom

    2D and 3D Measurements of Osteoarthritis Joint Space Width have Good Agreement in Radiographically Normal Knees but Poor Agreement with Advancing Kellgren-Lawrence Grade: Data from…
  • Abstract Number: 716 • 2016 ACR/ARHP Annual Meeting

    Radiographic Progression and Changes in Inflammation and Structural Damage on Serial MRI Examinations over 5 Years in Patients with Ankylosing Spondylitis Treated with TNF-Alpha Inhibitors

    Susanne Juhl Pedersen1, Ulrich Weber2, Roula Said Nahal3, Inge Juul Sorensen1, Anne Gitte Loft4, Niels Tvede1, Gina Kollerup1, Lars Juul1, Gorm Thamsborg1, Ole Rintek Madsen1, Jakob M. Møller5, Lone Balding6, Anne Grethe Jurik7 and Mikkel Østergaard8, 1Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen, Denmark, 2Department of Research, King Christian 10th Hospital for Rheumatic Diseases, Graasten, Denmark, 3Ambroise Paré Hospital, Boulogne-Billancourt, France, 4Departments of Rheumatology at Vejle and Aarhus Hospitals, Vejle and Aarhus, Denmark, 5Department of Radiology, Copenhagen University Hospital Herlev and Gentofte, Herlev, Denmark, 6Department of Radiology, Copenhagen University Hospital Herlev and Gentofte, Copenhagen, Denmark, 7Dept. of Radiology, Aarhus University Hospital, Aarhus, Denmark, 8Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Denmark, Copenhagen, Denmark

    Background/Purpose: Only few studies have investigated long-term radiographic progression in the spine of patients with ankylosing spondylitis (AS). Moreover, no studies have reported changes in…
  • Abstract Number: 1307 • 2016 ACR/ARHP Annual Meeting

    Anatomical Patterns Suggest the Involvement of Biomechanical Stress in the Pathogenesis of Erosions in Rheumatoid Arthritis

    Matthew A. Jessome1, Michael A. Tomizza1, Karen A. Beattie2, William G. Bensen2, Raja S. Bobba2, Alfred Cividino2, Patrick D. Emond2, Chris Gordon2, Lawrence Hart2, Maggie Larche2, Arthur Lau3, Ruben Tavares2, Stephen Tytus2 and Jonathan D. Adachi2, 1Faculty of Health Sciences, McMaster University, Hamilton, ON, Canada, 2St Joseph's Healthcare Hamilton, Hamilton, ON, Canada, 350 Charlton Avenue East, St Joseph's Healthcare Hamilton, Hamilton, ON, Canada

    Background/Purpose: There is limited data outlining the anatomic characteristics of bone erosions of the small joints in rheumatoid arthritis (RA). In particular, there is minimal…
  • Abstract Number: 893 • 2016 ACR/ARHP Annual Meeting

    Preliminary Results of a Multi Modal Imaging Study Suggests a Better Accuracy for the Diagnosis of Giant Cell Arteritis

    Augustin Lecler1, Samuel Bidot2, Frederique Charbonneau1, Sabine Derrien2, Herve Picard3 and Gaelle Clavel4, 1Department of Radiology, Fondation Ophtalmologique A. de Rothschild, Paris, France, 2Department of Ophthalmology, Fondation Ophtalmologique A. de Rothschild, Paris, France, 3Clinical Research Unit, Fondation Ophtalmologique A. de Rothschild, Paris, France, 4Department of Internal Medecine, Fondation Ophtalmologique A. de Rothschild, Paris, France

    Background/Purpose: Giant Cell Arteritis (GCA) is the most common systemic vasculitis in patient over 50 years of age. It is a medical emergency as it…
  • Abstract Number: 1494 • 2016 ACR/ARHP Annual Meeting

    Myocardial Structure, Function, and Fibrosis in Patients with Rheumatoid Arthritis and Matched Control Subjects

    Michelle J. Ormseth1, William Bradham2, Comfort Elumogo3, Srikanth Palanisamy4, Chia Liu5, Mark Lawson2, Jonathan Soslow2, Nadine Kawel6, David A. Bluemke7 and C Michael Stein2, 1Medicine, Vanderbilt University Medical Center, Nashville, TN, 2Vanderbilt University Medical Center, Nashville, TN, 3National Institutes of Health, Bethesada, MD, 4Cornell University, Ithaca, NY, 5National Institutes of Health, Bethsada, MD, 6National Institutes of Health, Bethsada, TN, 7National Institutes of Health, Bethesda, MD

    Background/Purpose: The prevalence of heart failure is increased 2-fold in RA; this is not explained by ischemic heart disease or other risk factors for heart…
  • Abstract Number: 907 • 2016 ACR/ARHP Annual Meeting

    Rituximab in Patients with Takayasu Arteritis: A Single Center Experience on Five Patients

    Giulia Pazzola1, Francesco Muratore1, Luigi Boiardi2, Mariagazia Catanoso1, Alessandra Soriano3, Pierluigi Macchioni1, Lucia Spaggiari4, Massimiliano Casali5, Nicolò Pipitone1, Niccolò Possemato6 and Carlo Salvarani1, 1Rheumatology Unit, Arcispedale S Maria Nuova, IRCCS, Reggio Emilia, Italy, 2Rheumatology Unit, Arcispedale S.Maria Nuova, IRCCS, Reggio Emilia, Italy, 3Rheumatology Unti, Arcispedale S Maria Nuova, IRCCS, Reggio Emilia, Italy, 4Radiology, Arcispedale S Maria Nuova, IRCCS, Reggio Emilia, Italy, 5Nuclear Medicine, Arcispedale S Maria Nuova, IRCCS, Reggio Emilia, Italy, 6Rheumatology Service, Arcispedale S Maria Nuova, IRCCS, Reggio Emilia, Italy

    Background/Purpose: Takayasu arteritis (TAK) is a large vessel vasculitis involving the aorta and its major branches in patients younger than 40 years. Glucocorticoids (GCs) are…
  • Abstract Number: 1776 • 2016 ACR/ARHP Annual Meeting

    Analysis of Progressive Brain and Corpus Callosum Atrophy and Association with Th1 and Th2 Cytokines in Systemic Lupus Erythematosus

    Mariana Postal1, Aline Tamires Lapa1, Karina O. Peliçari1, Nailu A. Sinicato2, Fernando A. Peres1, Wesley Geraldo Ferreira3, Lilian TL Costallat3, Fernando Cendes3 and Simone Appenzeller4, 1Medicine, State University of Campinas, Campinas, Brazil, 2Pediatrics, State University of Campinas, Campinas, Brazil, 3State University of Campinas, Campinas, Brazil, 4Division of Rheumatology, Faculty of Medical Science, State University of Campinas, São Paulo, Brazil

    Background/Purpose:  The pathophysiology of brain damage SLE is complex. The aim of this study was to determine brain atrophy progression and the association with Th1…
  • Abstract Number: 936 • 2016 ACR/ARHP Annual Meeting

    Reliability and Responsiveness of an Omeract Tenosynovitis Magnetic Resonance Imaging Scoring System for the Rheumatoid Arthritis Wrist and Hand

    Daniel Glinatsi1, Paul Bird2, Frédérique Gandjbakhch3,4, Espen A. Haavardsholm5, Philip G. Conaghan6 and Mikkel Østergaard7, 1Center for Rheumatology and Spine Diseases, Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen, Denmark, Glostrup, Denmark, 2Medicine, University of New South Wales, Sydney, NSW, Australia, 3Service de Rhumatologie, GH Pitié-Salpétrière, MD, Paris, France, 4Department of Rheumatology, APHP, Pitié Salpétrière Hospital, Universite Paris 6, Paris, France, 5Dept. of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, 6Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, 7Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Denmark, Copenhagen, Denmark

    Background/Purpose: Tenosynovitis in the hand occurs frequently and early in rheumatoid arthritis (RA) and sensitive outcome measures are important to assess and monitor the inflammatory…
  • Abstract Number: 1788 • 2016 ACR/ARHP Annual Meeting

    Alterations in Sense of Smell and Limbic Structures in Patients with Systemic Lupus Erythematosus during 3-Years Follow-up

    Fernando A. Peres1, Karina de Oliveira Peliçari1, Mariana Postal1, Nailu A. Sinicato2, Leticia Rittner3, Lilian Tereza Costallat4 and Simone Appenzeller5, 1Medicine, State University of Campinas, Campinas, Brazil, 2Pediatrics, State University of Campinas, Campinas, Brazil, 3UNICAMP, Sao Paulo, Brazil, 4RUA EZEQUIEL MAGALHAES,26, Unicamp, Campinas, Brazil, 5Pediatric Rheumatology Unit, State University of Campinas, Campinas, Brazil

    Background/Purpose: Many neurologic and neurodegenerative abnormalities are first demonstrable in the olfactory system with loss of smell up to 10 years before the onset of…
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