Abstracts tagged "MRI"

Abstract Number: 968 • 2018 ACR/ARHP Annual Meeting
What Is the Impact of Imaging on Diagnostic Ascertainment of Patients Presenting with Undiagnosed Back Pain in Routine Practice and the Impact of Central Reading? Data from the Screening in Axial Spondyloarthritis in Psoriasis, Iritis, and Colitis Cohort
Walter P. Maksymowych^1,2, Raj Carmona³, Jonathan Chan⁴, James Yeung⁵, Dianne P. Mosher⁶, Sibel Zehra Aydın⁷, Liam Martin⁶, Ariel Masetto⁸, Stephanie Keeling⁹, Olga Ziouzina⁶, Sherry Rohekar¹⁰, Joel Paschke², Amanda Carapellucci² and Robert G. Lambert¹¹, ¹Medicine, Medicine, University of Alberta, Edmonton, AB, Canada, ²CaRE Arthritis, Edmonton, AB, Canada, ³St. Joseph's Health Care, Hamilton, ON, Canada, ⁴Artus Health Clinic, Vancouver, BC, Canada, ⁵James Yeung Rheumatology, Richmond, BC, Canada, ⁶University of Calgary, Calgary, AB, Canada, ⁷Ottawa Hospital, Ottawa, ON, Canada, ⁸Centre Hospitalier Universitaire de Sherbrooke (CHUS), Faculté de médecine et des sciences de la santé, Université de Sherbrooke, Sherbrooke, AB, Canada, ⁹Medicine, University of Alberta, Edmonton, AB, Canada, ¹⁰Western University, London, ON, Canada, ¹¹Radiology, Radiology, University of Alberta, Edmonton, AB, Canada
Background/Purpose: Although MRI of the sacroiliac joints (SIJ) is the most sensitive imaging modality for early diagnosis of axial spondyloarthritis (axSpA) it is costly and…
Abstract Number: 2927 • 2018 ACR/ARHP Annual Meeting
What Are the Optimal MRI Lesion Cut-Offs That Define Active and Structural Lesions in the Sacroiliac Joint As Being Typical of Axial Spondyloarthritis By Expert Readers?
Walter P. Maksymowych^1,2, Pedro Machado³, Ulrich Weber⁴, Xenofon Baraliakos⁵, Joachim Sieper⁶, Stephanie Wichuk¹, Denis Poddubnyy⁶, Mikkel Østergaard⁷, Joel Paschke², Robert G. Lambert¹ and Susanne J Pedersen⁷, ¹University of Alberta, Edmonton, AB, Canada, ²CaRE Arthritis, Edmonton, AB, Canada, ³University College London, London, United Kingdom, ⁴University of Southern Denmark, Odense, Denmark, ⁵Rheumazentrum Ruhrgebiet Herne, Herne, Germany, ⁶Charité Universitätsmeidzin Berlin, Berlin, Germany, ⁷COPECARE University of Copenhagen, Copenhagen, Denmark
Background/Purpose: Defining what constitutes a definite MRI lesion in the SIJ typical of axSpA has been hampered by lack of international consensus for standardized lesion…
Abstract Number: 652 • 2018 ACR/ARHP Annual Meeting
Disease Interception in Psoriasis Patients with Subclinical Joint Inflammation By Interleukin 17 Inhibition with Secukinumab – Data from a Prospective Open Label Study
Eleni Kampylafka¹, Isabelle Oliveira¹, Christina Linz², Veronika Lerchen¹, Matthias Englbrecht¹, David Simon³, Michael Sticherling⁴, Juergen Rech⁵, Arnd Kleyer³, Georg Schett⁶ and Axel J. Hueber³, ¹Department of Internal Medicine 3 – Rheumatology and Immunology, Friedrich-Alexander-University Erlangen-Nürnberg, Erlangen, Germany, ²Department of Internal Medicine 3 – Rheumatology and Immunology, Friedrich-Alexander-University Erlangen-Nürnberg, e, Germany, ³Department of Internal Medicine 3—Rheumatology and Immunology, Friedrich-Alexander-University Erlangen–Nürnberg (FAU), Universitätsklinikum Erlangen, Erlangen, Germany, Erlangen, Germany, ⁴Department of Dermatology, Friedrich-Alexander-University Erlangen-Nürnberg, Erlangen, Germany, ⁵Universitätsklinikum Erlangen, Erlangen, Germany, ⁶Department of Internal Medicine 3, Rheumatology and Immunology, Universitätsklinikum Erlangen, Erlangen, Germany
Background/Purpose: Musculoskeletal changes precede the onset of psoriatic arthritis (PsA). A subset of psoriasis patients is characterized by arthralgia as well as inflammatory changes in…
Abstract Number: 1207 • 2018 ACR/ARHP Annual Meeting
Clinical Evaluation Correlates Poorly with Ultrasound and Magnetic Resonance Imaging of Joints and Entheses in Early Peripheral Spondyloarthritis
Thomas Renson¹, Ann-Sophie De Craemer¹, Philippe Carron¹, Simon Krabbe², Lennart Jans³, Manouk de Hooge⁴, Peggy Jacques¹, Mikkel Østergaard⁵, Dirk Elewaut¹ and Filip van Den Bosch⁶, ¹Department of Rheumatology, Ghent University Hospital, Ghent, 9000, Belgium, ²Copenhagen Center for Arthritis Research (COPECARE), Center for Rheumatology and Spine Diseases, Rigshospitalet, Centre for Head and Orthopaedics, Rigshospitalet, Glostrup, Denmark, ³Department of Radiology, Ghent University Hospital, Ghent, Belgium, ⁴Ghent University Hospital, Ghent, Belgium, ⁵Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Glostrup, Denmark, Copenhagen, Denmark, ⁶Department of Rheumatology, Ghent University Hospital, Ghent, Belgium
Background/Purpose: Enthesitis is a hallmark of spondyloarthritis (SpA), which occurs in 30 to 50% of psoriatic arthritis patients [1]. Evaluation of tenderness at the site…
Abstract Number: 653 • 2018 ACR/ARHP Annual Meeting
Validation of Assessments in Spondyloarthritis International Society MRI Lesion Definitions in Axial Spondyloarthritis: Data from the Echography in Spondyloarthritis Cohort
Walter P. Maksymowych^1,2, Damien Loeuille³, Stephanie Wichuk⁴, Joel Paschke⁵, Olivia Judet⁶, Maxime Breban³, Maria-Antonietta D'Agostino⁷ and Robert G. Lambert⁸, ¹University of Alberta, Edmonton, AB, Canada, ²CaRE Arthritis, Edmonton, AB, Canada, ³Ambroise Paré Hospital, Boulogne-Billancourt, France, ⁴Medicine, Medicine, University of Alberta, Edmonton, AB, Canada, ⁵CaRE Arthritis, Edmonton, Canada, Edmonton, AB, Canada, ⁶CHRU Vandoeuvre les Nancy, Vandœuvre-lès-Nancy, France, ⁷CHRU Vandoeuvre les Nancy, Vandoeuvre les Nancy, France, ⁸Radiology, Radiology, University of Alberta, Edmonton, AB, Canada
Background/Purpose: The diversity of MRI lesions in the sacroiliac joints of patients with axial spondyloarthritis (axSpA) has only recently been appreciated and consistent terminology, descriptions,…
Abstract Number: 1347 • 2018 ACR/ARHP Annual Meeting
A Semi-Quantitative Whole Body Magnetic Resonance Imaging Assessment Tool to Define Musculoskeletal Abnormalities in Patients with Idiopathic Inflammatory Myopathies
Sara Faghihi-Kashani¹, Lisa G. Rider², David Bluemke³, Ashkan Malayeri⁴, Evrim Turkbey⁴, Joseph Shrader⁵, John McGrath⁶, Elizabeth Jones⁷, Jamie Marco⁸, Frederick W. Miller⁹ and Adam Schiffenbauer¹⁰, ¹Environmental Autoimmunity Group, National Institute of Environmental Health, Bethesda, MD, ²Environmental Autoimmunity Group, National Institute of Environmental Health Sciences, National Institutes of Health, Bethesda, MD, ³Department of Radiology, University of Wisconsin School of Medicine and Public Health, Madison, WI, ⁴Radiology and Imaging Sciences, National Institutes of Health, Bethesda, MD, ⁵Rehabilitation Medicine, National Institutes of Health, Bethesda, MD, ⁶Social and Scientific Systems, Inc., Durham, NC, ⁷Radiology and Imaging Sciences, National Institutes of Health Clinical Center, Bethesda, MD, ⁸Radiology and Imaging Sciences National Institutes of Health, Bethesda, MD, ⁹Environmental Autoimmunity Group, NIEHS, NIH, Bethesda, MD, ¹⁰NIEHS, NIH, Bethesda, MD
Background/Purpose: There is a lack of standardized methodology for assessing whole body MRI (WBMRI) in idiopathic inflammatory myopathy (IIM) patients. This leads to difficulty in…
Abstract Number: 654 • 2018 ACR/ARHP Annual Meeting
MRI Lesion Definitions in Axial Spondyloarthritis: A Consensus Reappraisal from the Assessments in Spondyloarthritis International Society
Walter P. Maksymowych¹, Robert G. Lambert², Mikkel Østergaard³, Manouk de Hooge⁴, Susanne J Pedersen³, Alexander N Bennett⁵, Rubén Burgos-Vargas⁶, Iris Eshed⁷, Robert B.M. Landewé⁸, Pedro Machado⁹, Helena Marzo-Ortega¹⁰, Kay-Geert Hermann¹¹, Denis Poddubnyy¹¹, Martin Rudwaleit¹¹, Joachim Sieper¹², Désirée van der Heijde¹³, Irene van der Horst-Bruinsma¹⁴, Ulrich Weber¹⁵ and Xenofon Baraliakos¹⁶, ¹University of Alberta, Edmonton, AB, Canada, ²University of Alberta, Edmonton, AB, Cameroon, ³COPECARE University of Copenhagen, Copenhagen, Denmark, ⁴Ghent University Hospital, Ghent, Belgium, ⁵Rheumatology, Imperial College, London, United Kingdom, ⁶Universidad Nacional Autonoma de Mexico, Mexico City, Mexico, ⁷Radiology, Sheba Medical Center, Tel Aviv, Israel, ⁸Academic Medical Center Amsterdam, Amsterdam, Netherlands, ⁹University College London, London, United Kingdom, ¹⁰University of Leeds, Leeds, United Kingdom, ¹¹Charité Universitätsmeidzin Berlin, Berlin, Germany, ¹²Rheumatology, Charité Universitätsmeidzin Berlin, Berlin, Germany, ¹³Rheumatology, Leiden University Medical Ctr, Leiden, Netherlands, ¹⁴Rheumatology, VU University Medical Center, Amsterdam, Netherlands, ¹⁵University of Southern Denmark, Odense, Denmark, ¹⁶Rheumazentrum Ruhrgebiet Herne, Herne, Germany
Background/Purpose: There has been substantial progress in the characterization of MRI lesions in the sacroiliac joints (SIJ) and spine in axial spondyloarthritis (axSpA) since the…
Abstract Number: 1373 • 2018 ACR/ARHP Annual Meeting
Predictive Probabilities Are Superior in Communicating the Clinical Relevance of Cartilage Thickness As an Imaging Biomarker of Knee Osteoarthritis Progression
C. Kent Kwoh^1,2, Erin L. Ashbeck¹, Edward J. Bedrick³ and Felix Eckstein^4,5, ¹University of Arizona Arthritis Center, Tucson, AZ, ²Division of Rheumatology, Department of Medicine, The University of Arizona, Tucson, AZ, ³Department of Epidemiology and Biostatistics, University of Arizona, Tucson, AZ, ⁴Institute of Anatomy, Paracelsus Medical University, Salzburg, Austria, ⁵Chondrometrics GmbH, Ainring, Germany
Background/Purpose: Establishing a threshold of clinically important cartilage loss is of great interest for the design and interpretation of knee OA trials of structure-modifying treatments.…
Abstract Number: 302 • 2018 ACR/ARHP Annual Meeting
Validity and Responsiveness of Inflammation and Joint Damage Scores Based on the Omeract Rheumatoid Arthritis MRI Scoring System
Ulf Sundin¹, Mikkel Østergaard², Daniel Glinatsi³, Anna-Birgitte Aga⁴, Kim Hørslev-Petersen⁵, Merete Lund Hetland⁶, Peter Junker⁷, Bo Jannik Ejbjerg⁸, Paul Bird⁹, Philip G. Conaghan¹⁰, Siri Lillegraven⁴ and Espen A. Haavardsholm⁴, ¹*Dept. of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, ²Center for Rheumatology and Spine Diseases, Rigshospitalet Glostrup Copenhagen Center for Arthritis Research, Copenhagen, Denmark, ³Copenhagen Center for Arthritis Research (COPECARE), Center for Rheumatology and Spine Diseases, Rigshospitalet, Centre for Head and Orthopaedics, Rigshospitalet, Glostrup, Denmark, ⁴Dept. of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, ⁵King Christian 10th Hospital for Rheumatic Diseases, University of Southern Denmark, Institute of Regional Health Research, Graasten, Denmark, ⁶Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, The DANBIO Registry, Glostrup, Denmark, ⁷Odense University Hospital, Odense, Denmark, ⁸Department of Rheumatology, Zealand University Hospital, Køge, Denmark, ⁹Medicine, University of New South Wales, Sydney, NSW, Australia, ¹⁰University of Leeds, Leeds, United Kingdom
Background/Purpose: The RAMRIS scoring system is used to quantify synovitis, tenosynovitis, bone marrow edema (BME), bone erosions and joint space narrowing (JSN) on MRI examinations…
Abstract Number: 655 • 2018 ACR/ARHP Annual Meeting
Diagnostic Performance of MRI Lesions in the Sacroiliac Joints According to Updated Assessments in Spondyloarthritis International Society Lesion Definitions: A Central Reader Assessment of MRI Scans from the Assessments in Spondyloarthritis Classification Cohort
Walter P. Maksymowych^1,2, Xenofon Baraliakos³, Robert G. Lambert⁴, Pedro Machado⁵, Joachim Sieper⁶, Stephanie Wichuk⁷, Denis Poddubnyy⁶, Susanne J Pedersen⁸, Joel Paschke², Mikkel Østergaard⁸ and Ulrich Weber⁹, ¹Medicine, University of Alberta, Edmonton, AB, Canada, ²CaRE Arthritis, Edmonton, AB, Canada, ³Rheumazentrum Ruhrgebiet Herne, Herne, Germany, ⁴Radiology, Radiology, University of Alberta, Edmonton, AB, Canada, ⁵University College London, London, United Kingdom, ⁶Charité Universitätsmeidzin Berlin, Berlin, Germany, ⁷Medicine, Medicine, University of Alberta, Edmonton, AB, Canada, ⁸COPECARE University of Copenhagen, Copenhagen, Denmark, ⁹University of Southern Denmark, Odense, Denmark
Background/Purpose: The ASAS MRI group has generated updated consensus lesion definitions (ASAS_MRI_defn) for the spectrum of MRI lesions in the SIJ. Their relative performance as…
Abstract Number: 1445 • 2018 ACR/ARHP Annual Meeting
MRI Bone Erosions in RA Patients Relatives with Clinically Suspicious Arthralgia
David Vega-Morales¹, Jorge Esquivel-Valerio², Mario Alberto Garza-Elizondo³, Dionicio A. Galarza-Delgado⁴, Miguel A Villarreal-Alarcón⁵, Cassandra Skinner-Taylor¹, Diana Flores-Alvarado⁶, Janett Riega-Torres⁷, Lorena Pérez-Barbosa⁸, Brenda Vazquez-Fuentes⁹ and Maria Del Carmen Larios-Forte¹, ¹Rheumatology, University Hospital “Dr. José Eleuterio González”, UANL, Monterrey, Mexico, ²Rheumatology, University Hospital “Dr. José Eleuterio González”, UANL, Mexico, Monterrey, Mexico, ³Rheumatology, Hospital Universitario, UANL., Monterrey, Mexico, ⁴Chief of Rheumatology, Hospital Universitario, UANL, Monterrey, Mexico, ⁵Servicio de Reumatología, Departamento de Medicina Interna del Hospital Universitario “Dr. Jose Eleuterio González”, Universidad Autónoma de Nuevo León, Monterrey, Mexico, ⁶Servicio de Reumatología, Departamento de Medicina Interna del Hospital Universitario “Dr. José Eleuterio González”. Universidad Autónoma de Nuevo León, Monterrey, Mexico, ⁷University Hospital “Dr. José Eleuterio González”, UANL, Monterrey, Mexico, ⁸Hospital Universitario, Monterrey, Mexico, ⁹Servicio de Reumatología, Departamento de Medicina Interna. Hospital Universitario “Dr. José Eleuterio González”. Universidad Autónoma de Nuevo León, Monterrey, Mexico
Background/Purpose: Rheumatoid arthritis (RA) has a preclinical phase without symptoms that progress to symptomatic phases. Clinically suspect arthralgia (CSA) refers to patients with symptoms without…
Abstract Number: 304 • 2018 ACR/ARHP Annual Meeting
Dynamic MRI in Rheumatoid Arthritis for the Assessment of Synovitis Promoting Cartilage Loss
Philipp Sewerin¹, Anja Mueller-Lutz², Matthias Schneider³, Christoph Schleich⁴, Benedikt Ostendorf¹ and Stefan Vordenbäumen⁵, ¹Department and Hiller-Research-Unit for Rheumatology, Heinrich-Heine University, Düsseldorf, Germany, ²Department for diagnostic and interventional Radiology, Heinrich-Heine University, Düsseldorf, Germany, ³Department and Hiller-Research-Unit for Rheumatology, Heinrich-Heine University, Duesseldorf, Germany, ⁴Department for diagnostic and interventional Radiology, Heinrich-Heine University, Duesseldorf, Germany, ⁵Policlinic for Rheumatology & Hiller Research Centre for Rheumatology, Heinrich-Heine-University Duesseldorf, Düsseldorf, Germany
Background/Purpose: To investigate the local inflammatory activity of the synovium by using dynamic magnetic resonance imaging (MRI) and cartilage biochemical composition of the MCP-joints 2…
Abstract Number: 656 • 2018 ACR/ARHP Annual Meeting
What Is the Level of Agreement between Local and Central Readers in the Detection of Active and Structural MRI Lesions Typical of Axial Spondyloarthritis? Data from the Assessments in Spondyloarthritis Classification Cohort Study
Walter P. Maksymowych^1,2, Xenofon Baraliakos³, Robert G. Lambert⁴, Ulrich Weber⁵, Joachim Sieper⁶, Stephanie Wichuk¹, Denis Poddubnyy⁷, Mikkel Østergaard⁸, Joel Paschke², Susanne J Pedersen⁸ and Pedro Machado⁹, ¹Medicine, Medicine, University of Alberta, Edmonton, AB, Canada, ²CaRE Arthritis, Edmonton, AB, Canada, ³Rheumazentrum Ruhrgebiet Herne, Herne, Germany, ⁴Radiology, Radiology, University of Alberta, Edmonton, AB, Canada, ⁵University of Southern Denmark, Odense, Denmark, ⁶Charité Universitätsmeidzin Berlin, Berlin, Germany, ⁷Rheumatology, Charité Universitätsmeidzin Berlin, Berlin, Germany, ⁸COPECARE University of Copenhagen, Copenhagen, Denmark, ⁹University College London, London, United Kingdom
Background/Purpose: There has been no central reader evaluation of MRI scans from the ASAS Classification Cohort (ASAS-CC)1 to compare detection of lesions between central and…
Abstract Number: 1451 • 2018 ACR/ARHP Annual Meeting
The Value of Adding MRI to a Clinical Treat-to-Target Strategy in Rheumatoid Arthritis Patients in Clinical Remission: Clinical and Radiographic Outcomes from the Imagine-RA Randomized Controlled Trial
Signe Møller-Bisgaard¹, Kim Hørslev-Petersen², Bo Jannik Ejbjerg³, Merete Lund Hetland¹, Daniel Glinatsi⁴, Lykke Ørnbjerg¹, Jakob M. Møller⁵, Mikael Boesen⁶, Robin Christensen⁷, Kristian Stengaard-Pedersen⁸, Ole Rintek Madsen⁹, Bente Jensen¹⁰, Jan Alexander Villadsen¹¹, Ellen-Margrethe Hauge⁸, Philip Bennett¹², Oliver Hendricks², Karsten Asmussen¹³, Marcin Ryszard Kowalski¹⁴, Hanne Lindegaard¹⁵, Sabrina Mai Nielsen⁷, Henning Bliddal¹⁶, Niels Steen Krogh¹⁷, Torkell Ellingsen¹⁵, Agente Nielsen¹⁸, Lone Balding⁵, Anne Grethe Jurik¹⁹, Henrik S Thomsen⁵ and Mikkel Østergaard²⁰, ¹Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Centre for Head and Orthopaedics, Rigshospitalet, Copenhagen, Denmark, ²King Christian 10th Hospital for Rheumatic Diseases, University of Southern Denmark, Institute of Regional Health Research, Graasten, Denmark, ³Department of Rheumatology, Zealand University Hospital, Køge, Denmark, ⁴Copenhagen Center for Arthritis Research (COPECARE), Center for Rheumatology and Spine Diseases, Rigshospitalet, Centre for Head and Orthopaedics, Rigshospitalet, Glostrup, Denmark, ⁵Department of Radiology, Copenhagen University Hospital Herlev and Gentofte, Copenhagen, Denmark, ⁶Department of Radiology, Bispebjerg-Frederiksberg Hospital, Copenhagen, Copenhagen, Denmark, ⁷Musculoskeletal Statistics Unit, The Parker Institute, Bispebjerg and Frederiksberg, Denmark, ⁸Department of Rheumatology, Aarhus University Hospital, Department of Clinical Medicine, Aarhus, Denmark, ⁹Department of Rheumatology, Copenhagen University Hospital, Herlev and Gentofte, Hellerup, Denmark, ¹⁰Department of Rheumatology, Frederiksberg Hospital, Copenhagen, Denmark, Copenhagen, Denmark, ¹¹Department of Rheumatology, Silkeborg Hospital, Silkeborg, Denmark, ¹²Department of Rheumatology, Copenhagen University Hospital, Herlev and Gentofte, Copenhagen, Denmark, ¹³Department of Rheumatology, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Copenhagen, Denmark, ¹⁴Department of Rheumatology, Sygehus Vendsyssel, Hjørring, Hjørring, Denmark, ¹⁵Department of Rheumatology, Odense University Hospital, Odense, Denmark, ¹⁶The Parker Institute, Department of Rheumatology, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Copenhagen, Denmark, ¹⁷The DANBIO Registry, Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen, Denmark, ¹⁸Department of Radiology, Silkeborg Hospital, Silkeborg, Denmark, ¹⁹Department of Radiology, Aarhus University Hospital, Aarhus, Denmark, ²⁰Center for Rheumatology and Spine Diseases, Rigshospitalet Glostrup Copenhagen Center for Arthritis Research, Copenhagen, Denmark
Background/Purpose: Targeting MRI remission in rheumatoid arthritis (RA) patients in clinical remission may improve clinical outcome and halt joint damage progression. The purpose of the…
Abstract Number: 309 • 2018 ACR/ARHP Annual Meeting
Sub-Clinical Disease Activity in the Feet of Patients with Early Rheumatoid Arthritis: What Clinical Assessments Miss
Faiza Khokhar¹, Hanyan Zou², Myriam Allen¹, Saara Totterman³, Karen A. Beattie⁴ and Maggie Larche⁵, ¹Rheumatology, McMaster University, Hamilton, ON, Canada, ²McMaster University, Hamilton, ON, Canada, ³Qmetrics Technologies, Pittsford, NY, ⁴Medicine, McMaster University, Hamilton, ON, Canada, ⁵St Joseph's Healthcare Hamilton, Hamilton, ON, Canada
Background/Purpose: Early diagnosis of RA and effective monitoring of disease activity are important for treatment decision-making. Early treatment strategies can be effective in preventing the…

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