Session Type: ACR Poster Session A
Session Time: 9:00AM-11:00AM
Background/Purpose: Few studies showed signs of inflammation at the MRI of the sacroiliac joints (SIJ) or spine in only 30% of the non-radiographic axial spondyloarthritis (nr-axSpA) patients (1). Aims: 1) to evaluate inflammation at the MRI of the SIJ/ spine in TNF naïve nr-axSpA patients 2) consistency in case of absence of inflammation after 6 months and 3) evaluate gender differences
Methods: Consecutive patients with inflammatory back pain who were either HLA-B27 positive with ≥1 SpA-feature or HLA-B27 negative with ≥2 SpA-features, with high disease activity (BASDAI≥4), had an MRI of the SIJ and spine. In case of absence of inflammation, the MRI was repeated after six months. MRI images were scored according to the Spondyloarthritis Research Consortium of Canada (SPARCC spine, range 0-108; SPARCC SIJ, range 0-72) method
Results: Included were 70 patients, of whom 37 (53%) females. Half of the patients (36/69,52.2%) showed signs of inflammation on the first MRI: 27/69 patients (39.1%) at the SIJ, 14/46 patients (30.4%) at the spine and 4 patients (5.8%) on both sites and one patient missed the baseline MRI. Males had more often a positive MRI compared to females 62.5% vs. 43.2%. Patients with a positive MRI showed a median SPARCC score for SIJ of 8.0 (IQR: 1.8-23.5, higher in females) and for spine 6.5 (IQR: 2.8-10.8, higher in males).Only 4/33 patients (12.1%) showed a positive MRI after six months.
Conclusion: Fifty percent of the patients with nr-axSpA and high disease activity showed inflammatory lesions at the MRI of the SIJ and/or spine, which occurred more often in males compared to females. In most cases (87.9%) a MRI without inflammatory lesions remained negative after 6 months, indicating that a second MRI after a short period is not valuable.
To cite this abstract in AMA style:Rusman T, John ML, van der Weijden M, Boden B, van der Bijl J, Bruijnen S, van der Laken C, Nurmohamed MT, van der Horst-Bruinsma I. Diagnostic Value of MRI in Non-Radiographic Axial Spondyloarthritis [abstract]. Arthritis Rheumatol. 2018; 70 (suppl 10). https://acrabstracts.org/abstract/diagnostic-value-of-mri-in-non-radiographic-axial-spondyloarthritis/. Accessed June 15, 2021.
« Back to 2018 ACR/ARHP Annual Meeting
ACR Meeting Abstracts - https://acrabstracts.org/abstract/diagnostic-value-of-mri-in-non-radiographic-axial-spondyloarthritis/