ACR Meeting Abstracts

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Abstracts tagged "MRI"

  • Abstract Number: 867 • 2018 ACR/ARHP Annual Meeting

    An MRI Guided Treat-to-Target Strategy in Rheumatoid Arthritis Patients in Clinical Remission Improved MRI Inflammation but Not Damage Progression – Results from the Imagine-RA Randomized Controlled Trial

    Signe Møller-Bisgaard1, Kim Hørslev-Petersen2, Bo Jannik Ejbjerg3, Daniel Glinatsi4, Merete Lund Hetland1, Lykke Ørnbjerg1, Jakob M. Møller5, Mikael Boesen6, Robin Christensen7, Kristian Stengaard-Pedersen8, Ole Rintek Madsen9, Bente Jensen10, Jan Alexander Villadsen11, Ellen-Margrethe Hauge8, Philip Bennett12, Oliver Hendricks2, Karsten Asmussen13, Marcin Ryszard Kowalski14, Hanne Lindegaard15, Sabrina Mai Nielsen7, Henning Bliddal16, Niels Steen Krogh17, Torkell Ellingsen15, Agente Nielsen18, Lone Balding19, Anne Grethe Jurik20, Henrik S Thomsen19 and Mikkel Østergaard21, 1Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Centre for Head and Orthopaedics, Rigshospitalet, Copenhagen, Denmark, 2King Christian 10th Hospital for Rheumatic Diseases, University of Southern Denmark, Institute of Regional Health Research, Graasten, Denmark, 3Department of Rheumatology, Zealand University Hospital, Køge, Denmark, 4Copenhagen Center for Arthritis Research (COPECARE), Center for Rheumatology and Spine Diseases, Rigshospitalet, Centre for Head and Orthopaedics, Rigshospitalet, Glostrup, Denmark, 5Dept. of Radiology, Copenhagen University Hospitals, Herlev and Gentofte, Copenhagen, Denmark, 6Department of Radiology, Bispebjerg-Frederiksberg Hospital, Copenhagen, Copenhagen, Denmark, 7Musculoskeletal Statistics Unit, The Parker Institute, Bispebjerg and Frederiksberg, Denmark, 8Department of Rheumatology, Aarhus University Hospital, Department of Clinical Medicine, Aarhus, Denmark, 9Department of Rheumatology, Copenhagen University Hospital, Herlev and Gentofte, Hellerup, Denmark, 10Department of Rheumatology, Frederiksberg Hospital, Copenhagen, Denmark, Copenhagen, Denmark, 11Department of Rheumatology, Silkeborg Hospital, Silkeborg, Denmark, 12Department of Rheumatology, Copenhagen University Hospital, Herlev and Gentofte, Copenhagen, Denmark, 13Department of Rheumatology, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Copenhagen, Denmark, 14Department of Rheumatology, Sygehus Vendsyssel, Hjørring, Hjørring, Denmark, 15Department of Rheumatology, Odense University Hospital, Odense, Denmark, 16The Parker Institute, Department of Rheumatology, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Copenhagen, Denmark, 17The DANBIO Registry, Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen, Denmark, 18Department of Radiology, Silkeborg Hospital, Silkeborg, Denmark, 19Department of Radiology, Copenhagen University Hospital Herlev and Gentofte, Copenhagen, Denmark, 20Department of Radiology, Aarhus University Hospital, Aarhus, Denmark, 21Center for Rheumatology and Spine Diseases, Rigshospitalet Glostrup Copenhagen Center for Arthritis Research, Copenhagen, Denmark

    Background/Purpose: Magnetic Resonance Imaging (MRI) bone marrow edema (BME)/osteitis and MRI synovitis have been identified as predictors of structural damage progression in rheumatoid arthritis RA1,2.…
  • Abstract Number: 2508 • 2018 ACR/ARHP Annual Meeting

    A First-in-Man Bioelectronic Therapy for Biologic-Refractory Rheumatoid Arthritis

    David Chernoff1, Yaakov Levine1, Charles Peterfy2 and Mark C. Genovese3, 1SetPoint Medical, Inc., Valencia, CA, 2Spire Sciences LLC, Boca Raton, FL, 3Department of Medicine, Stanford University, Palo Alto, CA

    Background/Purpose: Rheumatoid arthritis (RA) is a debilitating chronic disease with an unmet need for additional therapeutic approaches. Bioelectronic therapy (BET), such as electrical neurostimulation of…
  • Abstract Number: 436 • 2018 ACR/ARHP Annual Meeting

    Structural Effects of Intra-Articular Sprifermin in Symptomatic Radiographic Knee Osteoarthritis: A Post-Hoc Analysis of Cartilage Morphology over the 2-Year Treatment-Period of a 5-Year Randomized, Placebo-Controlled, Phase II Study

    Ali Guermazi1, Jeffrey Kraines2, Aida Aydemir2, Stephen Wax3, Michel Crema4, Marc C. Hochberg5 and Frank Roemer1,6, 1Radiology, Boston University School of Medicine, Boston, MA, 2EMD Serono Research & Development Institute, Inc. (a business of Merck KGaA, Darmstadt, Germany), Billerica, MA, 3EMD Serono Research & Development Institute, Inc. (a business of Merck KGaA, Darmstadt, Germany), BIllerica, MA, 4Boston University School of Medicine, Boston, MA, 5University of Maryland School of Medicine, Baltimore, MD, 6Department of Radiology, University of Erlangen-Nuremberg, Erlangen, Germany, Erlangen, Germany

    Background/Purpose: Sprifermin, a recombinant human fibroblast growth factor 18, is currently being investigated as a potential disease-modifying OA drug. Sprifermin treatment leads to a dose-dependent…
  • Abstract Number: 897 • 2018 ACR/ARHP Annual Meeting

    Prevalence of Inflammatory and Chronic Changes Suggestive of Axial Spondyloarthritis in Magnetic Resonance Images of the Axial Skeleton in Individuals < 45 Years in the General Populationas Part of a Large Community Study (SHIP)

    Xenofon Baraliakos1, Daniel Feldmann2, Anne Ott2, Carsten Oliver Schmidt3, Martin Albers3, Adrian Richter3 and Jürgen Braun1, 1Ruhr-University Bochum, Herne, Germany, 2Rheumazentrum Ruhrgebiet, Herne, Germany, 3Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany

    Background/Purpose: Magnetic resonance imaging (MRI) is crucial for classification and diagnosis of axial spondyloarthritis (axSpA). Characteristic MRI lesions of axSpA are bone marrow edema (BME)…
  • Abstract Number: 2601 • 2018 ACR/ARHP Annual Meeting

    Nonsteroidal Anti-Inflammatory Drugs Attenuate Active Inflammatory Sacroiliac Joint Lesions in Patients with Early Axial Spondyloarthritis

    Hong-Ki Min1, Hyonjoung Cho2 and Sung-Hwan Park3, 1Division of Rheumatology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea, Republic of (South), 2Division of Rheumatology, Department of Internal Medicine, Armed Forces Capital hospital, Armed Forces Medical Command, Seongnam, Korea, Republic of (South), 3Division of Rheumatology, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea, Republic of (South)

    Background/Purpose: The purpose of the present study was to examine the therapeutic effect of NSAIDs on active inflammatory lesions (bone marrow oedema [BMO]) in the…
  • Abstract Number: 449 • 2018 ACR/ARHP Annual Meeting

    Pain Processing in Chronic Low Back Pain Individuals with or without Sick Leave

    Aloma Feitosa1, Liliana Jorge2, Liana Sanches2, Eduardo Ferreira Borba3, Edson Amaro2 and Ari Halpern1,2, 1Rheumatology, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, SP, BR, Sao Paulo, Brazil, 2Instituto do Cérebro, Hospital Israelita Albert Einstein, Sao Paulo, Brazil, 3Rheumatology Division, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil

    Background/Purpose: Chronic low back pain (LBP) is one of the most common musculoskeletal complaints in industrialized societies. It affects 80% of the adult population at…
  • Abstract Number: 922 • 2018 ACR/ARHP Annual Meeting

    Anakinra Treatment Prevents Myocardial Mechanical Dysfunction and Inhibits Histologic Evidence of Myocardial Inflammation in the Mouse Model of Kawasaki Disease

    Mark Gorelik1,2, Youngho Lee3, Masanori Abe4, Thomas Andrews5, Jean Patterson1, Magali Noval Rivas4, Gregory Aune5 and Moshe Arditi4, 1Immunology and Virology, Texas Biomedical Research Institute, San Antonio, TX, 2Pediatrics, Baylor College of Medicine, Houston, TX, 3Department of Cell Biology, Hospital for Sick Children, Toronto, ON, Canada, 4Pediatrics, Cedars Sinai, Beverly Hills, CA, 5Greehey Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, TX

    Background/Purpose: Kawasaki disease (KD) is an acute, febrile illness of childhood with sequelae of coronary artery aneurysms and cardiac fibrosis, and is the most common…
  • Abstract Number: 2784 • 2018 ACR/ARHP Annual Meeting

    Multi Modal Imaging Algorithm to Improve the Accuracy for the Diagnosis of Giant Cell Arteritis

    Augustin Lecler1, Thomas Sené2, Herve Picard3, Tifenn Leturcq2, Kevin Zuber3, Frederique Charbonneau1, Catherine Vignal-Clermont4 and Gaelle Clavel2, 1Department of Radiology, Fondation Ophtalmologique A. de Rothschild, Paris, France, 2Internal Medecine, Fondation Ophtalmologique A. de Rothschild, Paris, France, 3Clinical Research Unit, Fondation Ophtalmologique A. de Rothschild, Paris, France, 4Ophtalmology, Fondation Ophtalmologique A. de Rothschild, Paris, France

    Background/Purpose: Giant Cell Arteritis (GCA) is the most common systemic vasculitis in patient over 50 years of age. It is a medical emergency as it…
  • Abstract Number: 591 • 2018 ACR/ARHP Annual Meeting

    Evaluation of MRI Ramris Score and Clinical Response in Patients with ACPA Positive Undifferentiated Arthritis Treated with Infliximab Versus Placebo

    Thomas Kirchgesner1, Bruno Vande Berg1, Tatiana Sokolova2, Laurent Meric de Bellefon2, Adrien Nzeusseu Toukap3, Maria Stoenoiu4 and Patrick Durez2, 1Musculoskeletal Imaging Unit, Musculoskeletal Imaging Unit - Cliniques universitaires Saint-Luc - Université Catholique de Louvain - Institut de Recherche Expérimentale et Clinique (IREC), Brussels, Belgium, 2Rheumatology, Rheumatology - Cliniques universitaires Saint-Luc - Université Catholique de Louvain - Institut de Recherche Expérimentale et Clinique (IREC), Brussels, Belgium, 3Department of Rheumatology, Rheumatology - Cliniques universitaires Saint-Luc - Université Catholique de Louvain - Institut de Recherche Expérimentale et Clinique (IREC), Brussels, Belgium, 4Rheumatology department, Rheumatology - Cliniques universitaires Saint-Luc - Université Catholique de Louvain - Institut de Recherche Expérimentale et Clinique (IREC), Brussels, Belgium

    Background/Purpose: Patients (Pts) with Undifferentiated Arthritis (UA), positive for ACPA antibodies are at high risk of progressing to Rheumatoid Arthritis (RA). TNF play a key…
  • Abstract Number: 953 • 2018 ACR/ARHP Annual Meeting

    Evaluating MRI-Detected Knee Inflammation Prior to Total Knee Replacement As a Predictive Biomarker of Clinically Important Pain Reduction Two Years Later

    Manjinder Kaur1, Lili Zhou2, Erin L. Ashbeck2, Ernest Vina3, Frank Roemer4, Ali Guermazi5, David J. Hunter6 and C. Kent Kwoh1,2, 1Division of Rheumatology, Department of Medicine, The University of Arizona, Tucson, AZ, 2University of Arizona Arthritis Center, Tucson, AZ, 3University of Arizona School of Medicine, University of Arizona Arthritis Center, Tucson, AZ, 4Department of Radiology, Boston University School of Medicine, Boston, MA, USA, Boston, MA, 5Boston University School of Medicine, Boston, MA, 6University of Sydney, Sydney, Australia

    Background/Purpose: Some patients do not experience clinical improvement after total knee replacement (TKR). Presence of structural abnormalities on MRI before surgery may inform pain prognosis…
  • Abstract Number: 2908 • 2018 ACR/ARHP Annual Meeting

    Agreement between Ultrasound and Whole Body Magnetic Resonance Imaging Assessment of Joint Inflammation and Enthesitis in Rheumatoid Arthritis Patients

    Sin Ngai Ng1, Mette Bjørndal Axelsen2, Mikkel Østergaard3, Iris Eshed4, Merete Lund Hetland2, Jakob M. Møller5, Susanne J Pedersen6,7 and Lene Terslev8, 1Medicine, Queen Elizabeth Hospital , Hong Kong, Hong Kong, Hong Kong, 2Copenhagen Center for Arthritis Research, Copenhagen, Denmark, 3Center for Rheumatology and Spine Diseases, Rigshospitalet Glostrup Copenhagen Center for Arthritis Research, Copenhagen, Denmark, 4Department of Radiology, Sheba Medical Center, Israel, Tel Hashomer, Israel, 5Dept. of Radiology, Copenhagen University Hospitals, Herlev and Gentofte, Copenhagen, Denmark, 6Depart of Rheumatology VRR, Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen, Denmark, Copenhagen, Denmark, 7Dept. of Rheumatology, Copenhagen Center for Arthritis Research, Copenhagen, Denmark, 8Copenhagen Center for Arthritis Research (COPECARE), Center for Rheumatology and Spine Diseases, Rigshospitalet, Centre for Head and Orthopaedics, Rigshospitalet, Glostrup, Denmark

    Background/Purpose: To evaluate the agreement between ultrasound (US), whole body magnetic resonance imaging (WBMRI) and clinical assessment of joint inflammation and enthesitis in rheumatoid arthritis…
  • Abstract Number: 608 • 2018 ACR/ARHP Annual Meeting

    Half Dose Reduction of Methotrexate in Patient with RA Who Achieved Clinical Remission

    Takeshi Suzuki, Takayasu Ando, Shoshi Shinagawa, Machiko Mizushima, Tomohiko Shibata and Kimito Kawahata, Division of Rheumatology and Allergology, Department of Internal Medicine, St. Marianna University School of Medicine, Kawasaki, Japan

    Background/Purpose: Recently, it is recommended that tapering csDMARDs could be considered If a patient is in persistent remission. However, the methods of tapering csDMARDs including…
  • Abstract Number: 955 • 2018 ACR/ARHP Annual Meeting

    Lower Limb Muscle Strength and Protection Against Functional Decline and Structural Worsening in Knee Osteoarthritis

    Alison H. Chang1, Joan S. Chmiel2, Orit Almagor1, Karen W. Hayes1, Ali Guermazi3, Prasad Pottumarthi4, Kirsten C. Moisio1, Yunhui Zhang1, Julie Szymaszek1 and Leena Sharma5, 1Northwestern University Feinberg School of Medicine, Chicago, IL, 2Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, 3Boston University School of Medicine, Boston, MA, 4NorthShore University HealthSystem, Evanston, IL, 5Division of Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL

    Background/Purpose: Lower limb muscle weakness has been proposed as a factor contributing to functional decline and structural progression. Hip abductor strengthening, in addition to quadriceps…
  • Abstract Number: 2926 • 2018 ACR/ARHP Annual Meeting

    Which MRI Lesions in the Sacroiliac Joint Are Associated with the Diagnosis of Axial Spondyloarthritis after 2 Years Follow up in the Echography in Spondyloarthritis Cohort?

    Walter P. Maksymowych1,2, Damien Loeuille3, Stephanie Wichuk4, Joel Paschke5, Olivia Judet6, Maxime Breban3, Maria-Antonietta D'Agostino7 and Robert G. Lambert8, 1University of Alberta, Edmonton, AB, Canada, 2CaRE Arthritis, Edmonton, AB, Canada, 3Ambroise Paré Hospital, Boulogne-Billancourt, France, 4Medicine, Medicine, University of Alberta, Edmonton, AB, Canada, 5CaRE Arthritis, Edmonton, Canada, Edmonton, AB, Canada, 6CHRU Vandoeuvre les Nancy, Vandœuvre-lès-Nancy, France, 7CHRU Vandoeuvre les Nancy, Vandoeuvre les Nancy, France, 8Radiology, Radiology, University of Alberta, Edmonton, AB, Canada

    Background/Purpose: MRI of the sacroiliac joint (SIJ) is emerging as an important prognostic tool for assessment of patients presenting with axSpA. A major challenge in…
  • Abstract Number: 651 • 2018 ACR/ARHP Annual Meeting

    Analysis of the Different Value of Magnetic Resonance Imaging Changes in the Sacroiliac Joints for a Diagnosis of Axial Spondyloarthritis As Judged By Rheumatologists and Radiologists

    Xenofon Baraliakos1, Ana Ghadir2, Martin Fruth2, Uta Kiltz3 and Jürgen Braun1, 1Ruhr-University Bochum, Herne, Germany, 2Rheumazentrum Ruhrgebiet, Herne, Germany, 3Rheumatology, Rheumazentrum Ruhrgebiet, Herne, and Ruhr University Bochum, Herne, Germany

    Background/Purpose: Classification of axial spondyloarthritis (axSpA) by the imaging arm of the ASAS criteria relies partly on the detection of a bone marrow edema (BME)…
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Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. Academic institutions, private organizations and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part a scientific presentation or presentation of additional new information that will be available at the time of the meeting) is under embargo until Saturday, November 11, 2023.

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