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Abstracts tagged "Mortality"

  • Abstract Number: 0274 • ACR Convergence 2025

    Transplant-free survival in patients with systemic autoimmune rheumatic diseases and progressive pulmonary fibrosis in the ILD-PRO Registry

    Sonali Bracken1, Aparna Swaminathan2, Jeremy M Weber3, Megan L Neely4, Scott Palmer4, Erin Wilfong5, Ann Chauffe6 and Elizabeth Volkmann7, 1Duke University Medical Center, Durham, NC, USA, Apex, NC, 2Duke University Medical Center and Duke Clinical Research Institute, Durham, NC, USA, Durham, NC, 3Duke Clinical Research Institute, Durham, NC, USA, Durham, 4Duke University Medical Center and Duke Clinical Research Institute, Durham, NC, USA, Durham, 5Vanderbilt University Medical Center, Nashville, TN, USA, Nashville, TN, 6Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, CT, USA, Newberry, FL, 7Division of Rheumatology, Department of Medicine, University of California, David Geffen School of Medicine, Los Angeles, CA, USA, Los Angeles, CA

    Background/Purpose: Progressive pulmonary fibrosis (PPF) is known to be associated with high mortality, but there are few data on the course of PPF in patients…
  • Abstract Number: 2074 • ACR Convergence 2025

    Increased Mortality in Hispanic Males with Lymphopenia: A Descriptive and Statistical Analysis of Anti-Melanoma Differentiation-Associated Protein 5 (MDA-5) Antibody Positive Patients

    Sergio Maldonado Chaar1 and Kelly Corbitt2, 1University of Miami/Jackson Health, Miami, FL, 2University of Miami Miller School of Medicine, El Portal, FL

    Background/Purpose: Anti-melanoma differentiation-associated protein 5 (MDA-5) antibody positivity in dermatomyositis (DM) is often associated with development of interstitial lung disease (ILD), with factors such as…
  • Abstract Number: 1567 • ACR Convergence 2025

    Deep-learning analysis of HRCT images predicts progression and mortality in systemic sclerosis-related interstitial lung disease

    Enrico De Lorenzis1, Rosa D'Abronzo2, Pier Giacomo Cerasuolo3, Lucio Calandriello4, Gabriella Alonzi3, Giuseppe Cicchetti2, gerlando Natalello3, Bruno Iovene5, Lucia Lanzo3, Francesco Varone6, Giacomo Sgalla7, Luca Richeldi8, anna Rita Larici4, Maria Antonietta D'Agostino3 and Silvia Laura Bosello9, 1Catholic University of the Sacred Heart, Roma, Rome, Italy, 2Division of Radiology - Università Cattolica del Sacro Cuore, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italy, 3Division of Rheumatology and Clinical Immunology - Università Cattolica del Sacro Cuore, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy, 4Division of Radiology - Università Cattolica del Sacro Cuore, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy, 5Division of Rheumatology - Catholic University of the Sacred Heart, Fondazione Policlinico Universitario Agostino Gemelli, Rome, Rome, Italy, 6Division of Respiratory Medicine - Università Cattolica del Sacro Cuore, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy, 7Catholic University of the Sacred Heart, Fondazione Policlinico Universitario Agostino Gemelli, Rome, Rome, Italy, 8Division of Respiratory Medicine - Università Cattolica del Sacro Cuore, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italy, 9Division of Rheumatology and Clinical Immunology - Catholic University of the Sacred Heart, Rome, Italy, Rome, Italy

    Background/Purpose: Interstitial lung disease (ILD) is a major complication in systemic sclerosis (SSc) patients, associated with substantial morbidity and mortality. Functional, imaging, and clinical measures…
  • Abstract Number: 0703 • ACR Convergence 2025

    Trends and Disparities in Systemic Sclerosis-related Mortality Rates in the United States from 1999 to 2023

    Nicolas Barnechea Alvarado1, Khadija Mohib1, Rameez Qasim2 and Muhammad Ali3, 1Kirk Kerkorian School of Medicine at UNLV, Las Vegas, NV, 2Allama Iqbal Medical College Lahore, Lahore, Pakistan, 3Dow International Medical College, Karachi, Sindh, Pakistan

    Background/Purpose: Systemic sclerosis is one of the most fatal rheumatologic diseases, with significantly higher mortality rates compared to the general population, likely due to its…
  • Abstract Number: 0269 • ACR Convergence 2025

    Clinical Landscape and Severity Markers of VEXAS Syndrome in a Spanish Cohort: Findings from VEXASSER Study Group

    Paula García-Escudero1, Marta López2, Berta Magallares3, Dolly Viviana Fiallo Suárez4, Diego Dios Santos5, César Antonio Egües Dubuc6, Santos Castañeda7, Alicia Garcia8, Isla Morante Bolado9, Elena María Oliver García10, Clara Garcia Belando11, Cristina Corrales12, Francisco Javier Toyos13, Judit Font-Urgelles14, Meritxell Salles Lizarzaburu15, Carolina Merino16, Irene Carrion17, Jose Angel Hernandez18, Lourdes Villalobos19, Alina-Lucica Boteanu20, Beatriz Frade Sosa21, cristiana Sieiro22, Irene Monjo Henry23, Ernesto Trallero24, Eugenia Enriquez25, Maria Rodriguez26, Elena Riera Alonso27, Marta Ibañez28, Delia Reina29, Rafael Benito Melero González30, Giuliano Boselli31, Alberto Mariano32, Ignacio Vázquez Gómez33, Jose Alberto Miranda34, Clara Moriano35, Elena Aurrecoechea36, Paloma Vela Casasempere37, Iñigo Rúa-Figueroa38 and Jaime Calvo39, 1Hospital Universitario Álava, Bilbao, Spain, 2Complex Hospitalari Universitari Moisés Broggi, Barcelona, Spain, 3Hospital de Sant Pau, Bareclona, 4H.U. Doctor Negrín, Gran Canarias, 5C. H. U. A Coruña, A Coruña, Spain, 6Rheumatology Department, Donostia University Hospital., San Sebastian, Spain, 7Hospital Universitario de La Princesa, IIS-Princesa, Madrid, Madrid, Spain, 8Rheumatologist, La Laguna, Spain, 9Rheumatology, Hospital General Sierrallana, Torrelavega, Spain., Santander, 10H.C. U. Lozano Blesa, Zaragoza, 11H.C. U. Virgen de la arrizaca, Murcia, 12HOSPITAL UNIVERSITARIO MARQUES DE VALDECILLA, Santander, Spain, 13Virgen Macarena University Hospital,, Sevilla, Spain, 14Hospital Universitari Germans Trias i Pujol, Badalona, Spain, 15Rheumatology Department, Althaia Xarxa Assistencial Universitària Manresa Manresa (Spain)., Manresa, Spain, 16Rheumatology department. Hospital Universitario Puerta de Hierro Majadahonda, Majadahonda (Madrid), Madrid, Spain, 17Hospital del Mar, Barcelona, Spain, 18Hospital Universitario Insular de Gran Canaria, Las Palmas de Gran CanariaHospital, Spain, 19Ramon y Cajal Hospital, MADRID, Spain, 20H.U. Ramón y Cajal, Madrid, Spain, 21Hospital Clinic de Barcelona, Barcelona, Catalonia, Spain, 22Univrsity of Manchester, Manchester, United Kingdom, 23Hospital Universitario La Paz, Madrid, Spain, 24H. U. Vall d'Hebron, Barcelona, 25Clínica Universidad de Navarra, Madrid, Spain, 26H. Clínico San Carlos, Madrid, Spain, 27Hospital Universitari Mùtua Terrassa, Terrassa, Spain, 28Hospital Universitario de la Santa Creu i Sant Pau, Barcelona, Catalonia, Spain, 29Complex Hospitalari Moisès Broggi, Barcelona, Spain, 30C. H. U. de Ourense, Ourense, 31Rheumatology Division, Hospital Universitario Miguel Servet , Zaragoza, Spain, Zaragoza, Aragon, Spain, 32Virgen del Rocío University Hospital, Sevilla, Spain, 33H.U. Doctor Peset, Valencia, 34C. H. U. Lucus Augusti, Lugo, Spain, 35Hospital León, LEON, Castilla y Leon, Spain, 36H. Sierrallana, Santander, 37Hospital General Universitario Alicante, Alicante, Comunidad Valenciana, Spain, 38Hospital de Gran Canaria Doctor Negrin, Las Palmas GC, Spain, 39Department of Rheumatology, Hospital Universitario Araba, School of Medicne, Universidad del País Vasco, BIOARABA Health Research Institute, Vitoria, Spain, Vitoria, Pais Vasco, Spain

    Background/Purpose: VEXAS syndrome is a rare disease caused by somatic mutations in UBA1 gene. Different mutations in this gene appear to be associated with specific…
  • Abstract Number: 0615 • ACR Convergence 2024

    Socioeconomic Determinants of Lupus Hospitalization Outcomes: A Review of Current Knowledge and Analysis of the 2016-2019 NRD Database

    Akhila Arya P V1, Madhumitha Rondla2, Jai Juganya Tirupur Ponnusamy3 and Dileep C Unnikrishnan4, 1Bridgeport Hospital, Stratford, CT, 2Texas tech university health sciences center, El paso, El Paso, TX, 3Metrowest Medical Center, Framingham, 4Bridgeport Hospital, Bridgeport, CT

    Background/Purpose: Hospitalizations due to systemic lupus erythematosus (SLE) often stem from lupus flares and infections. Socioeconomic factors influencing outcomes in SLE hospitalizations have been studied…
  • Abstract Number: 1087 • ACR Convergence 2024

    Sex Differences in Clinical Features and Mortality in Gout: A Nationwide Retrospective Cohort Study

    HYUNSUE DO1, Kwanyoung Choe2, Min Jung Kim3, Kichul Shin4 and Ki Won Moon5, 1Kangwon national university hospital, Seoul, South Korea, 2Yeongjusi Health Center, Yeongjusi, Republic of Korea, 3Seoul Metropolitan Government Boramae Medical center, Dongjak-gu, Seoul, South Korea, 4Seoul Metropolitan Government- Seoul National University Boramae Medical Center, Seoul, South Korea, 5Kangwon National University hospital, Chuncheon-si, Republic of Korea

    Background/Purpose: Patients with gout have several coexisting conditions that impact mortality. Studies on clinical features and mortality of female patients with gout are limited, as…
  • Abstract Number: 2203 • ACR Convergence 2024

    The Association of Autoantibodies with Clinical Manifestations and Long-term Outcomes in Juvenile- and Adult-onset Systemic Sclerosis

    Hideaki Tsuji1, Ryosuke Hiwa1, Mirei Shirakashi2, Shuji Akizuki3, Ran Nakashima1, Akira Onishi4, Hajime Yoshifuji1, Masao Tanaka4 and Akio Morinobu5, 1Department of Rheumatology and Clinical Immunology, Kyoto University Graduate School of Medicine, Kyoto, Japan, 2Department of Rheumatology and Clinical Immunology, Kyoto University Graduate School of Medicine, Kyoto, 3Department of Rheumatology and Clinical Immunology, Kyoto University Graduate School of Medicine, Kyoto City, Japan, 4Department of Advanced Medicine for Rheumatic Diseases, Kyoto University Graduate School of Medicine, Kyoto, Japan, 5Department of Rheumatology and Clinical Immunology, Graduate School of Medicine, Kyoto University, Kyoto, Japan., Kyoto, Japan

    Background/Purpose: Our aim is to explore whether clinical features and long-term outcomes depend on autoantibodies in juvenile- and adult-onset systemic sclerosis (SSc), since they were…
  • Abstract Number: 2494 • ACR Convergence 2024

    Clinical Characteristics, Predictors for Mortality and Comparison of the Birmingham Vasculitis Activity Score and the Five-Factor Score on Survival in ANCA-associated Vasculitis in Hong Kong : A Multi-centre Retrospective Cohort Study

    Ka Ho Yeung and Kit Yu Young, Caritas Medical Centre, Hong Kong, Hong Kong

    Background/Purpose: To describe the clinical profile and predictors of mortality of AAV patients in Hong Kong. To compare the accuracy of the latest Five-factor Score…
  • Abstract Number: 0619 • ACR Convergence 2024

    Prevalence and Factors Predicting Hemophagocytic Lymphohistiocytosis in Hospitalized Patients with Systemic Lupus Erythematosus

    OKEOGHENE AKPOIGBE1, BETTINA ESCOLANO2, ENOCH J ABBEY2 and Amanda Sammut3, 1New York City Health and Hospitals/Harlem in Affliation with Columbia University, NEW YORK, NY, 2New York City Health and Hospitals/Harlem in Affliation with Columbia University, NEW YORK, 3New York City Health and Hospitals/Harlem. Rheumatology Department, Chappaqua, NY

    Background/Purpose: Systemic lupus erythematosus (SLE) complicated with hemophagocytic lymphohistiocystosis (HLH) can be life-threatening with mortality as high as 9.9%-10.5%. Estimates of the prevalence of HLH…
  • Abstract Number: 1116 • ACR Convergence 2024

    Understanding the Prevalence, In-Hospital Mortality and Readmission Rates Amongst Pulmonary vs Cardiac Sarcoidosis Patients: Insights from a Nationwide Registry

    Shivang Chaudhary1, Kaushik Gokul1, Kishan Patel2, Simran Bhimani3, Yash Deshpande3, Adam Kilian1, Ravi Nayak1, Deana Mikhalkova1 and Chaitanya Rojulpote1, 1Saint Louis University, St. Louis, MO, 2Riverside Community Hospital, Riverside, CA, 3The Wright Center for graduate medical education, Scranton, PA

    Background/Purpose: Sarcoidosis is a complex, multisystemic disorder predominantly affecting the pulmonary system but can also involve extra-pulmonary organs such as the heart. Mortality in sarcoidosis…
  • Abstract Number: 2210 • ACR Convergence 2024

    Comparison of Dual RF and Anti-CCP Seropositive, Single Seropositive, and Seronegative RA on Radiographic Changes, Flares, and Mortality

    Rebecca Brooks1, Sara Achenbach2, Vanessa Kronzer1, Elena Myasoedova1, Cynthia Crowson1 and John Davis1, 1Mayo Clinic, Rochester, MN, 2Mayo Clinic, Rochester, Rochester, MN

    Background/Purpose: Both RF and anti-CCP are associated with erosive disease, increased disease activity, and adverse outcomes in RA. However, there have been limited studies investigating how…
  • Abstract Number: 2532 • ACR Convergence 2024

    Mortality in Patients with Pre-existing Autoimmune Disease on Immune Checkpoint Inhibitor Therapy

    Gregory Challener1, kevin sheng-kai ma1, Minna Kohler1, Chio Yokose2 and Hyon K. Choi3, 1Massachusetts General Hospital, Boston, MA, 2Massachusetts General Hospital, Waltham, MA, 3Massachusetts General Hospital, Lexington, MA

    Background/Purpose: There is growing awareness that immunotherapy-related adverse events (iRAE) from immune checkpoint inhibitor (ICI) therapy are being correlated with treatment outcomes of various cancers.…
  • Abstract Number: 0645 • ACR Convergence 2024

    Mortality and Ethnicity in Adults with Systemic Lupus Erythematosus: A Systematic Literature Review and Meta-Analysis

    Samir Patel1, Zijing Yang1, deepak Nagra1, Maryam Adas2, Mark Russell1, Sam Norton1, Chris Wincup3, James Galloway4, Kate Bramham2 and Patrick Gordon5, 1King's College London, London, England, United Kingdom, 2King's College London, London, United Kingdom, 3King's College Hospital, London, United Kingdom, 4Centre for Rheumatic Diseases, King's College London, London, United Kingdom, 5nhs, London, United Kingdom

    Background/Purpose: Ethnicity and health outcomes are intrinsically interrelated, although mechanisms are complex. Systemic lupus erythematosus (SLE) is a disease with higher incidence in non-White populations…
  • Abstract Number: 1144 • ACR Convergence 2024

    Autoantibody and Radiological Profiles as Prognostic Indicators in Idiopathic Inflammatory Myopathies: Insights into Mortality and Interstitial Lung Disease Development

    cristiana sieiro santos1, Miriam Retuerto2, Laura Sierra2, Jose Ordas Martínez3, Paula Pérez García2, Pedro Baenas2, Clara Moriano Morales2 and Elvira Díez Álvarez4, 1Rheumatology Department, Complejo Asistencial Universitario de León, León, Spain, Leon, Spain, 2Complejo Asistencial Universitario de León, León, Spain, 3Complejo Asistencial Universitario de Leon, Leon, 4Complejo Asistencial Universitario de León, Leon, Spain

    Background/Purpose: The idiopathic inflammatory myopathies (IIMs) constitute a diverse group of acquired muscle disorders, often involving multiple organs such as the skin, heart, and lungs.…
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