ACR Meeting Abstracts

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Abstracts tagged "meta-analysis"

  • Abstract Number: 1471 • ACR Convergence 2024

    Sex-related Differences in Efficacy and Safety Outcomes in Axial Spondyloarthritis Randomized Clinical Trials: A Systematic Literature Review and Meta-analysis

    Angel Gao1, Jordi Pardo Pardo2, Steven Dang3, Lianne S Gensler4, Philip Mease5 and Lihi Eder6, 1Queens University, Kingston, Canada, 2University of Ottawa, Ottawa, Canada, 3Women's College Hospital, Institute of Medical Science, University of Toronto, Toronto, ON, Canada, 4Department of Medicine/Rheumatology, University of California, San Francisco, San Francisco, CA, 5Swedish Medical Center/Providence St. Joseph Health; University of Washington School of Medicine, Seattle, WA, 6University of Toronto, Women’s College Hospital and Department of Medicine, Toronto, ON, Canada

    Background/Purpose: Limited information exists on sex-related differences in axial spondyloarthritis (axSpA) randomized controlled trials (RCTs). Through a systematic literature review and meta-analysis we aimed to assess…
  • Abstract Number: 1498 • ACR Convergence 2024

    Gender Disparities in Clinical Manifestations and Outcomes of Systemic Lupus Erythematosus: A Systematic Review and Meta-Analysis

    Mazen Allouni1, Muhammad Shamim2, Krista Topalsky3 and Omer Pamuk4, 1Case Western Reserve, University Hospitals, Cleveland Medical Center, Cleveland, OH, 2University Hospitals/ Case Western Reserve University, Cuyahoga Falls, OH, 3University Hospitals/ Case Western Reserve University, Shaker Heights, OH, 4University Hospitals Cleveland Medical Center/ Case Western Reserve University, Cleveland, OH

    Background/Purpose: The clinical manifestations and outcomes of systemic lupus erythematosus (SLE) reveal notable gender differences, which may impact treatment strategies and patient outcomes. This meta-analysis…
  • Abstract Number: 0029 • ACR Convergence 2024

    Effect of Metformin on the Incidence of Total Knee Replacement: A Systematic Review and Meta-Analysis

    Syed Hasan1, Aali Furqan2, Afia Salman3, hira Khan4, Sarah Aslam5, Alishba Rizvi4, Hafsah Alim Ur Rahman3, Muhammad Ahmed Ali Fahim3, Madiha Salman3, Eman Ali3, Yumna Furqan6, Shanta bai7, Farah Yasmin8 and Muhammad Sohaib Asghar9, 1Dow University of Health Sciences, Karachi, PK., Karachi, Sindh, Pakistan, 2University of North Texas Health Science Center (UNT HSC), Texas, TX, 3Dow University of Health Sciences, Karachi, Pakistan, 4dow medical college, Karachi, Pakistan, 5Dow International Medical College, Karachi, Pakistan, 6Texas A&M School of Medicine, Dallas, TX, 7Liaquat National Hospital and Medical College, Karachi, Pakistan, 8Yale University School of Medicine, New Haven, CT 06511, U.S.A., New Haven, CT, 9AdventHealth, Sebring, FL

    Background/Purpose: Osteoarthritis (OA) is among the most common debilitating conditions, causing disability and pain in older adults. For end-stage OA, total knee replacement (TKR) is…
  • Abstract Number: 1524 • ACR Convergence 2024

    Thrombocytopenia and Systemic Lupus Erythematosus: A Meta-analysis of Observational Studies

    Alexandre Matar1 and Omer Pamuk2, 1MetroHealth, Westlake, OH, 2University Hospitals Cleveland Medical Center/ Case Western Reserve University, Cleveland, OH

    Background/Purpose: Thrombocytopenia is one of the hematological abnormalities that can occur in patients with systemic lupus erythematosus (SLE), and it has been shown to affect…
  • Abstract Number: 0228 • ACR Convergence 2024

    Do Imaging Tests Have a Role in Predicting Progression to Rheumatoid Arthritis in People with Clinically Suspect Arthralgia? A Systematic Review & Meta-Analysis

    Ankita Gupta1, Sulaiman Anis2 and Paola de Pablo2, 1Sandwell and West Birmingham Hospitals NHS Trust, Birmingham, United Kingdom, 2University of Birmingham, Birmingham, United Kingdom

    Background/Purpose: Clinically suspect arthralgia (CSA) has been associated with an increased risk of developing inflammatory arthritis (IA). Subclinical inflammation on imaging tests may help to…
  • Abstract Number: 1525 • ACR Convergence 2024

    Early versus Late Lupus Nephritis: A Meta-analysis of Observational Studies

    Alexandre Matar1 and Omer Pamuk2, 1MetroHealth, Westlake, OH, 2University Hospitals Cleveland Medical Center/ Case Western Reserve University, Cleveland, OH

    Background/Purpose: Systemic Lupus Erythematosus (SLE) is a chronic systemic autoimmune disorder characterized by a broad range of clinical and immunological manifestations, one of which is…
  • Abstract Number: 0474 • ACR Convergence 2024

    Association Between Rheumatoid Arthritis and Survival After Cancer: A Systematic Literature Review and Meta-analysis

    Joshua Hsieh1, Avneet Kaur2, Hemant Khandelia3, Teresa Jewell4, Aman Singh5, Lauren Barkley6, Ishan Bansal7, Simmi Oberoi8 and Namrata Singh9, 1Lakeside High School, Seattle, WA, 2SUNY Upstate, Buffalo, NY, 3AIIMS, New Delhi, Delhi, India, 4University of Washington, Seattle, WA, 5Rajindra Hospital, Patiala, Punjab, India, 6Brandeis University, Boston, MA, 7Yale University, New Haven, CT, 8Rajindra Hospital, New Delhi, India, 9University of Washington, Bellevue, WA

    Background/Purpose: Increasing evidence suggests that inflammation, a hallmark of rheumatoid arthritis (RA), is associated with an elevated risk of cancer and can influence cancer outcomes.…
  • Abstract Number: 1535 • ACR Convergence 2024

    Variations in Tacrolimus Whole Blood Concentrations During Pregnancy and Its Implications for Therapeutic Drug Monitoring: A Systematic Review and Meta-analysis

    Reem Farhat1, Arielle Mendel2, Isabelle Malhamé2, Ami Grunbaum3, Sasha Bernatsky4 and Evelyne Vinet2, 1McGill University, Montreal, QC, Canada, 2McGill University Health Centre, Montreal, QC, Canada, 3Research Institute of the McGill University Health Centre, Montréal, QC, Canada, 4Research Institute of the McGill University Health Centre, Montreal, QC, Canada

    Background/Purpose: Tacrolimus is a pregnancy-compatible immunosuppressive increasingly used in systemic lupus erythematosus (SLE) pregnancies. Physiological changes throughout pregnancy impact tacrolimus pharmacokinetics, altering the drug’s whole…
  • Abstract Number: 0480 • ACR Convergence 2024

    Can’t Sleep, Won’t Sleep: A Systematic Review and Meta-Analysis of Insomnia Prevalence in 70,105 Rheumatoid Arthritis Patients

    Mohamed Abdelsalam1, Mamdouh Ahmed Khairy2, Mohamed Reda Awad3, Aly Alnabawy2, Maryam Taha4 and Mohamed Al-Adl Ali Ali2, 1Rheumatology, Rehabilitation and Physical medicine department - faculty of medicine -Misr University for science and technology, 6th of October, Al Jizah, Egypt, 2Faculty of medicine - Al-Azhar university Cairo branch, Cairo, Egypt, 3Al Azhar University, Cairo, Egypt, Giza, Egypt, 4Faculty of medicine - Ain Shams university, Madinat Nasr, Al Qahirah, Egypt

    Background/Purpose: Insomnia is a significant challenge for rheumatoid arthritis (RA) patients. Chronic pain conditions often exacerbate sleep disturbances, creating a vicious cycle where pain and…
  • Abstract Number: 2050 • ACR Convergence 2024

    Clinical Enthesitis Concerns Half the Patients with Psoriatic Arthritis, Is More Frequent in Trials Than in Observational Studies and Is Assessed Heterogeneously: A Systematic Review with Meta-analysis of 84,262 Patients from 212 Studies

    caroline pignon1, Laure Gossec2, Bruno Fautrel3, Clementina López Medina4 and Noemie bibas5, 1Faculté de médecine Créteil, PARIS, France, 2Sorbonne Université, Paris, France, 3INSERM, UMRS 1136, Institut Pierre Louis d'Epidémiologie et de Santé Publique, and Sorbonne University – Assistance Publique-Hôpitaux de Paris, Département de Rhumatologie, Hôpital Pitié-Salpêtrière, Paris, Ile-de-France, France, 4Reina Sofia University Hospital, Cordoba, Spain, 5Sorbonne Université, paris

    Background/Purpose: Enthesitis is considered a hallmark of psoriatic arthritis (PsA), however data on the frequency and consequences of enthesitis are conflicting. To analyze clinical enthesitis in…
  • Abstract Number: 0595 • ACR Convergence 2024

    bDMARD Drug Survival in Combination Therapy with Methotrexate in Psoriatic Arthritis: A Systematic Literature Review and Meta-analysis

    Sélina HANNA ABDELMASSIH1, Tiphaine DUJARDIN2, Athan BAILLET1, Philippe GAUDIN1 and Xavier ROMAND1, 1Centre hospitalier universitaire Grenoble-Alpes, Grenoble, France, 2Hôpital Reine Hortense, Aix-les-Bains, France

    Background/Purpose: During the last two decades we’ve witnessed the rising use of biologic disease-modifying antirheumatic drugs (bDMARDs) in the treatment of psoriatic arthritis (PsA), leaving…
  • Abstract Number: 2117 • ACR Convergence 2024

    The Risk of Medication-related Osteonecrosis of the Jaw (MRONJ) in a Patient with Osteoporosis Treated with Antiresorptive Therapy and Undergoing Dental Care Is Negligible with a CTX Threshold Above 260

    Camille Ghio, Robinson Gravier-Dumonceau, Pierre Lafforgue, Roch Giorgi and Thao Pham, Assistance Publique-Hôpitaux de Marseille, Marseille, France

    Background/Purpose: Although antiresorptive treatments, including bisphosphonates and denosumab, have demonstrated their efficacy in treating osteoporosis. However, osteonecrosis of the jaw has been reported as a…
  • Abstract Number: 0599 • ACR Convergence 2024

    Sex- related Differences in Efficacy of Biologics in Axial Spondyloarthritis: A Systematic Review and Meta-analysis

    Haseeb Chaudhary1, Omer Pamuk2, Sarah Abi Doumeth3, Ansaam Daoud4, Muhammad Shamim5 and Marina Magrey6, 1Case Western Reserve University, Westlake, OH, 2University Hospitals Cleveland Medical Center/ Case Western Reserve University, Cleveland, OH, 3Case Western Reserve University/University Hospitals Cleveland Medical Center, Cleveland Heights, OH, 4Case Western Reserve University/University Hospitals, Akron, OH, 5University Hospitals/ Case Western Reserve University, Cuyahoga Falls, OH, 6Case Western Reserve University School of Medicine/University Hospitals, Richfield, OH

    Background/Purpose: There is limited information about sex-related differences in efficacy of biologics in axial spondyloarthritis (axSpA).  We hypothesized that females with axSpA are less likely…
  • Abstract Number: 2510 • ACR Convergence 2024

    The Effect of Coronary Artery Aneurysms and IVIG Use on Long-term Cardiovascular Disease and Mortality Following Kawasaki Disease in Childhood: A Systematic Review and Meta-analysis

    Francis Lao1, Cal Robinson2, Dorota Borovski3, KAREN BEATTIE4, Joycelyne Ewusie5, Rahul Chanchlani3 and Michelle Batthish6, 1The Hospital for Sick Children, Hamilton, ON, Canada, 2The Hospital for Sick Children, Toronto, ON, Canada, 3McMaster University, Hamilton, Canada, 4McMaster University, Hamilton, ON, Canada, 5McMaster University, Hamilton, 6McMaster Children's Hospital, Hamilton, ON, Canada

    Background/Purpose: Kawasaki Disease (KD) is a common childhood vasculitis. Coronary artery aneurysms (CAAs) develop in approximately 25% of untreated KD patients. However, there is limited…
  • Abstract Number: 0648 • ACR Convergence 2024

    Prevalence of Pulmonary Complications Among Patients with Systemic Lupus Erythematosus (SLE): A Systematic Review and Meta-analysis

    Athanasios Vassilopoulos1, Stephanos Vassilopoulos2, Jasneet Singh2, Ingrid Lazaridou2, Markos Kalligeros2, Eleftherios Mylonakis3 and Anthony M. Reginato4, 1Warren Alpert Medical School of Brown University, Providence, RI, 2Division of Internal Medicine, Warren Alpert Medical School of Brown University, Rhode Island Hospital, Providence, Rhode Island, Providence, RI, 3Department of Medicine, Houston Methodist Hospital, Houston, 4Brown University, Providence, RI

    Background/Purpose: Pleuritis remains the most common pulmonary manifestation in patients with SLE.  The prevalence of other less common complications of SLE such as: interstitial lung…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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