Abstracts tagged "Magnetic resonance imaging (MRI)"

Abstract Number: 0162 • ACR Convergence 2021
Cardiac Magnetic Resonance Imaging for Guiding Decision-making on Treatment Duration: Data from RHAPSODY, a Phase 3 Clinical Trial of Rilonacept in Recurrent Pericarditis
Paul Cremer¹, David Lin², Alistair Wheeler³, Antonio Abbate⁴, Antonio Brucato⁵, Fang Fang⁶, Antonella Insalaco⁷, Martin LeWinter⁸, Basil S. Lewis⁹, Sushil A. Luis¹⁰, Stephen J. Nicholls¹¹, John Petersen¹², Allan Klein¹, Massimo Imazio¹³ and John F Paolini⁶, ¹Department of Cardiovascular Imaging, Center for the Diagnosis and Treatment of Pericardial Diseases, Heart and Vascular Institute, Cleveland Clinic, Cleveland, OH, ²Minneapolis Heart Institute at Abbott Northwestern Hospital, Minneapolis, MN, ³Kiniksa Pharmaceuticals, Ltd., Hamilton, Bermuda, ⁴VCU Pauley Heart Center, Virginia Commonwealth University, Richmond, VA, ⁵Department of Biomedical and Clinical Science, University of Milano, Fatebenefratelli Hospital, Milan, Italy, ⁶Kiniksa Pharmaceuticals Corp., Lexington, MA, ⁷Department of Pediatric Medicine, Division of Rheumatology, Bambino Gesù Children's Hospital, Rome, Italy, ⁸Cardiology Unit, The University of Vermont Medical Center, The University of Vermont, Burlington, VT, ⁹Cardiovascular Clinical Research Institute, Lady Davis Carmel Medical Center, Haifa, Israel, ¹⁰Division of Cardiovascular Ultrasound, Department of Cardiovascular Medicine, Mayo Clinic, Rochester, NY, ¹¹MonashHeart, Department of Cardiology, Monash University, Clayton, Australia, ¹²Swedish Medical Center, Seattle, WA, ¹³University Cardiology, Cardiovascular and Thoracic Department, AOU Città della Salute e della Scienza di Torino, Torino, Italy
Background/Purpose: The magnitude of pericardial delayed hyperenhancement (DHE) by cardiac magnetic resonance imaging (CMR) illustrates the severity of inflammation in pericarditis. We hypothesized that patients…
Abstract Number: 0852 • ACR Convergence 2021
Bone Marrow Lesion Segmentation Using Synthetic Data and Deep Learning Models
Barak Michaely¹, Ming Zhang² and Juan Shan¹, ¹Pace University, New York, NY, ²Wentworth Institute of Technology, Boston, MA
Background/Purpose: Bone marrow lesions (BML) are indicators for knee osteoarthritis (OA) and can be detected from magnetic resonance imaging (MRI). Due to the small size,…
Abstract Number: 0181 • ACR Convergence 2021
Magnetic Resonance Imaging Findings in Early Rheumatoid Arthritis: Are There Differences Based on Autoantibody Status?
Caitrin Coffey¹, Gavin McKenzie¹, Nicholas Rhodes¹, Cassondra Hulshizer¹, Cynthia Crowson², John Davis¹ and Kerry Wright¹, ¹Mayo Clinic, Rochester, MN, ²Mayo Clinic, Eyota, MN
Background/Purpose: Magnetic resonance imaging (MRI) is increasingly used as an adjunct to the physical examination in early rheumatoid arthritis (RA). Characteristic differences in MRI findings…
Abstract Number: 0898 • ACR Convergence 2021
MRI Vertebral Corner Inflammation and Fat Deposition Are Associated with Whole Spine Low Dose CT Detected Syndesmophytes: A Multilevel Analysis
Rosalinde Stal¹, Xenofon Baraliakos², Alexandre Sepriano³, Floris van Gaalen¹, Sofia Ramiro¹, Rosaline van den Berg¹, Monique Reijnierse¹, Juergen Braun², Robert Landewé⁴ and Désirée van der Heijde⁵, ¹Leiden University Medical Center, Leiden, Netherlands, ²Rheumazentrum Ruhrgebiet Herne, Ruhr-Universität Bochum, Herne, Germany, ³Leiden University Medical Center, Lisbon, Portugal, ⁴Amsterdam Rheumatology & Clinical Immunology Center, Amsterdam, Netherlands; Zuyderland MC, Heerlen, Netherlands, ⁵Department of Rheumatology, Leiden University Medical Center, Meerssen, Netherlands
Background/Purpose: In previous studies vertebral corner inflammation (VCI) and vertebral corner fat deposition (VCFD) were associated with syndesmophyte formation on cervical and lumbar conventional radiography.…
Abstract Number: 0213 • ACR Convergence 2021
Quantitative Assessment of Volumetric Change in Hip Effusion Using Artificial Intelligence in Patients with Osteoarthritis of the Hip
Jacob Jaremko¹, Banafshe Felfeliyan², Abhilash Hareendranathan¹, Bashiar Thejeel¹, Vanessa Quinn-Laurin¹, Mikkel Ostergaard³, Philip Conaghan⁴, Robert Lambert¹, Janet Ronsky² and Walter Maksymowych¹, ¹University of Alberta, Edmonton, AB, Canada, ²University of Calgary, Calgary, AB, Canada, ³Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Glostrup, and Department of Clinical Medicine, University of Copenhagen, Glostrup, Denmark, ⁴Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom
Background/Purpose: Accurate quantification of hip effusion volume may aid effective OA management as synovitis of the hip has been associated with pain and structural damage…
Abstract Number: 0901 • ACR Convergence 2021
Low Dose Dual Energy CT Scan for the Detection of Bone Marrow Edema and Erosions in Axial Spondyloarthritis
Jonathan Chan¹, Savvas Nicolaou¹, Yet Yen Yan², Mahomed Osman³, Hugue Ouellette¹ and Sabeena Jalal⁴, ¹University of British Columbia, Vancouver, BC, Canada, ²Changi General Hospital, Singapore, ³Queensland X-ray, Brisbane, Australia, ⁴Harvard School of Public Health, Boston, USA, Boston, MA
Background/Purpose: Bone marrow edema (BME) and erosions of the sacroiliac (SI) joints are key imaging features in the diagnosis of axial spondyloarthritis (axSpA). MRI with…
Abstract Number: 0216 • ACR Convergence 2021
Distribution of Medial Femur and Tibia Cartilage Volume Change over 48 Months on MRI: Comparison Among Kellgren-Lawrence Grades
Rebecca Amesbury¹, Hedieh Ragati Haghi¹, Todd Laffaye¹, Rebekah Stein¹, Erin Ashbeck², C. Kent Kwoh³, Alexander Mathiessen¹ and Jeffrey Duryea¹, ¹Brigham and Women's Hospital, Boston, MA, ²University of Arizona Arthritis Center, Tucson, AZ, ³University of Arizona College of Medicine, Tuscon, AZ
Background/Purpose: Semi-automated Local Area Cartilage Segmentation (LACS) software uses two robust coordinate systems to measure cartilage change in focused regions in the femur and tibia.…
Abstract Number: 0903 • ACR Convergence 2021
Scoring MRI Structural Lesions in Sacroiliac Joints of Patients with Axial Spondyloarthritis: How Many Slices Are Optimal?
Walter Maksymowych¹, Ulrich Weber², Xenofon Baraliakos³, Pedro Machado⁴, Susanne Pedersen⁵, Joachim Sieper⁶, Stephanie Wichuk⁷, Denis Poddubnyy⁸, Martin Rudwaleit⁹, Désirée van der Heijde¹⁰, Robert Landewé¹¹, Joel Paschke¹², Mikkel Ostergaard¹³ and Robert Lambert⁷, ¹Department of Medicine, University of Alberta, Alberta, Canada, Edmonton, AB, Canada, ²Practice Buchsbaum Schaffhausen, Schaffhausen, Switzerland, ³Rheumazentrum Ruhrgebiet Herne, Ruhr-Universität Bochum, Herne, Germany, ⁴Centre for Rheumatology & Department of Neuromuscular Diseases, University College London, London, United Kingdom, ⁵Rigshospitalet, Center for Arthritis Research, Glostrup, Denmark, ⁶Department of Gastroenterology, Infectiology and Rheumatology (including Nutrition Medicine), Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany, ⁷University of Alberta, Edmonton, AB, Canada, ⁸Department of Rheumatology, Charité – Universitätsmedizin, Berlin, Germany, ⁹University of Bielefeld, Klinikum Bielefeld, Bielefeld, Germany, ¹⁰Department of Rheumatology, Leiden University Medical Center, Meerssen, Netherlands, ¹¹Amsterdam Rheumatology & Clinical Immunology Center, Amsterdam, Netherlands; Zuyderland MC, Heerlen, Netherlands, ¹²CARE Arthritis, Edmonton, AB, Canada, ¹³Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Glostrup, and Department of Clinical Medicine, University of Copenhagen, Glostrup, Denmark
Background/Purpose: There is no international consensus on the optimal number of slices for evaluation of MRI structural lesions in the SIJ. An “all slice” method…
Abstract Number: 0217 • ACR Convergence 2021
The OMERACT Knee Inflammation MRI Scoring System: Validation of Quantitative Methodologies and Tri-compartmental Overlays by Comparison with the MRI Osteoarthritis Knee Score
Walter Maksymowych¹, Jacob Jaremko², Susanne Pedersen³, Iris Eshed⁴, Ulrich Weber⁵, Paul Bird⁶, Andrew McReynolds², Stephanie Wichuk², Joel Paschke⁷ and Robert Lambert², ¹Department of Medicine, University of Alberta, Alberta, Canada, Edmonton, AB, Canada, ²University of Alberta, Edmonton, AB, Canada, ³Rigshospitalet, Center for Arthritis Research, Glostrup, Denmark, ⁴Sheba Medical Center, Ramat Gan, Israel, ⁵Practice Buchsbaum Schaffhausen, Schaffhausen, Switzerland, ⁶University of New South Wales, Sydney, Australia, ⁷CARE Arthritis, Edmonton, AB, Canada
Background/Purpose: Bone marrow lesions (BML) and synovitis on MRI are independently associated with the severity and progression of osteoarthritis (OA) and randomized controlled trials have…
Abstract Number: 0904 • ACR Convergence 2021
Data-driven Definitions Based on Inflammatory Lesions for a Positive MRI of the Spine Consistent with Axial Spondyloarthritis
Walter Maksymowych¹, Robert Lambert², Xenofon Baraliakos³, Susanne Pedersen⁴, Iris Eshed⁵, Ulrich Weber⁶, Pedro Machado⁷, Manouk de Hooge⁸, Joachim Sieper⁹, Stephanie Wichuk², Denis Poddubnyy¹⁰, Martin Rudwaleit¹¹, Robert Landewé¹², Désirée van der Heijde¹³ and Mikkel Ostergaard¹⁴, ¹Department of Medicine, University of Alberta, Alberta, Canada, Edmonton, AB, Canada, ²University of Alberta, Edmonton, AB, Canada, ³Rheumazentrum Ruhrgebiet Herne, Ruhr-Universität Bochum, Herne, Germany, ⁴Rigshospitalet, Center for Arthritis Research, Glostrup, Denmark, ⁵Sheba Medical Center, Ramat Gan, Israel, ⁶Practice Buchsbaum Schaffhausen, Schaffhausen, Switzerland, ⁷Centre for Rheumatology & Department of Neuromuscular Diseases, University College London, London, United Kingdom, ⁸Ghent University Hospital, Ghent, Belgium, ⁹Department of Gastroenterology, Infectiology and Rheumatology (including Nutrition Medicine), Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany, ¹⁰Department of Rheumatology, Charité – Universitätsmedizin, Berlin, Germany, ¹¹University of Bielefeld, Klinikum Bielefeld, Bielefeld, Germany, ¹²Amsterdam Rheumatology & Clinical Immunology Center, Amsterdam, Netherlands; Zuyderland MC, Heerlen, Netherlands, ¹³Department of Rheumatology, Leiden University Medical Center, Meerssen, Netherlands, ¹⁴Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Glostrup, and Department of Clinical Medicine, University of Copenhagen, Glostrup, Denmark
Background/Purpose: The ASAS definition of a positive MRI for inflammation in the spine (ASAS-MRI+) is intended for classification of patients as having axSpA but is…
Abstract Number: 0219 • ACR Convergence 2021
Intra-Articular Mineralization on Knee CT and Risk of Cartilage Loss: The Multicenter Osteoarthritis Study
Jean Liew¹, John Lynch², Ali Guermazi¹, Mohamed Jarraya³, David Felson¹, Na Wang¹, Cora Lewis⁴, James Torner⁵, Michael Nevitt⁶ and Tuhina Neogi⁷, ¹Boston University, Boston, MA, ²University of California San Francisco, San Francisco, CA, ³Massachusetts General Hospital, Boston, MA, ⁴University of Alabama Birmingham, Birmingham, AL, ⁵University of Iowa, Iowa City, IA, ⁶University of California San Francisco, Orinda, CA, ⁷Boston University School of Medicine, Boston, MA
Background/Purpose: Intra-articular (IA) mineralization due to crystal deposition may contribute to OA pathology through inflammation, release of pro-catabolic factors, or altered cartilage biomechanical properties. Prior…
Abstract Number: 0905 • ACR Convergence 2021
Artificial Neural Network for the Recognition of Active Inflammatory Changes Compatible with Axial Spondyloarthritis on Magnetic Resonance Imaging of Sacroiliac Joints
Denis Poddubnyy¹, Janis Vahldiek², Lisa Adams², Torsten Diekhoff², Fabian Proft², Mikhail Protopopov², Judith Rademacher², Valeria Rios Rodriguez², Murat Torgutalp², Stefan Niehues² and Keno Bressem², ¹Department of Rheumatology, Charité – Universitätsmedizin, Berlin, Germany, ²Charité University Medicine Berlin, Berlin, Germany
Background/Purpose: Active inflammatory changes in sacroiliac joints (SIJ) compatible with axial spondyloarthritis - axSpA (first of all, subchondral bone marrow edema – BME / osteitis)…
Abstract Number: 0230 • ACR Convergence 2021
Fatigue and Inflammation in Rheumatoid Arthritis Are Already Disconnected Before Clinical Arthritis Develops
Sarah J.H. Khidir¹, Annette H.M van der Helm-van Mil¹ and Elise van Mulligen², ¹Leiden University Medical Center, Leiden, Netherlands, ²Erasmus Medical Center, Rotterdam, Netherlands
Background/Purpose: Fatigue is disabling and common in Rheumatoid Arthritis (RA); the causation of fatigue in RA is multidimensional and only partially explained by inflammation. The…
Abstract Number: 0921 • ACR Convergence 2021
Effect of Secukinumab on Radiographic Progression and Inflammation in Sacroiliac Joints and Spine in Patients with Non-radiographic Axial Spondyloarthritis: 2-year Imaging Outcomes from a Phase III Randomized Trial
Juergen Braun¹, Ricardo Blanco², Helena Marzo-Ortega³, Lianne Gensler⁴, Filip Van den Bosch⁵, Stephen Hall⁶, Hideto Kameda⁷, Denis Poddubnyy⁸, Marleen van de Sande⁹, Désirée van der Heijde¹⁰, Tingting Zhuang¹¹, Anna Stefanska¹², Aimee Readie¹¹, Hanno Richards¹³ and Atul Deodhar¹⁴, ¹Rheumazentrum Ruhrgebiet Herne, Ruhr-Universität Bochum, Herne, Germany, ²Hospital University Marqués de Valdecilla, IDIVAL, Division of Rheumatology, Santander, Spain, ³NIHR Leeds Biomedical Research Centre and University of Leeds, Leeds, United Kingdom, ⁴Department of Rheumatology, University of California San Francisco, San Francisco, CA, ⁵Dept. of Rheumatology - Ghent University Hospital, Ghent, Belgium, Ghent, Belgium, ⁶Emeritus Research and Monash University, Melbourne, Australia, Melbourne, Australia, ⁷Division of Rheumatology, Department of Internal Medicine, Faculty of Medicine, Toho University, Tokyo, Japan, ⁸Department of Rheumatology, Charité – Universitätsmedizin, Berlin, Germany, ⁹Amsterdam UMC, University of Amsterdam, Amsterdam Rheumatology and Immunology Center, Amsterdam, Netherlands, ¹⁰Department of Rheumatology, Leiden University Medical Center, Meerssen, Netherlands, ¹¹Novartis Pharmaceuticals Corporation, East Hanover, NJ, ¹²Novartis Ireland Limited, Dublin, Ireland, Dublin, Ireland, ¹³Novartis Pharma AG, Basel, Switzerland, ¹⁴Oregon Health & Science University, Portland, OR
Background/Purpose: Axial spondyloarthritis (axSpA) is characterized by inflammation of the sacroiliac joints (SIJ) and the spine. Secukinumab (SEC) treatment was clinically efficacious and reduced SIJ…
Abstract Number: 0305 • ACR Convergence 2021
Artificial Neural Networks Approaches to Predict Myocardial Fibrosis in Primary Sjögren Syndrome Patients Without Cardiac Symptoms
Hitomi Kobayashi¹, Yasuyuki Kobayashi², Atsuma Nishiwaki¹, Isamu Yokoe¹, Haraoka Masaki³, Eichi Takaya³, Yousuke Nagasawa¹, Noboru Kitamura¹, Masami Takei¹ and Hideki Nakamura¹, ¹Nihon University School of Medicine, Itabashi, Japan, ²St. Marianna University School of Medicine, kowasaki, Japan, ³St. Marianna University School of Medicine, Kawaski, Japan
Background/Purpose: A recent meta-analysis of cardiovascular diseases demonstrated that the odds of heart failure (HF) was more than 2.54-fold higher in primary Sjögren syndrome (pSS)…

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