Abstracts tagged "Magnetic resonance imaging (MRI)"

Abstract Number: 1108 • ACR Convergence 2020
Cartilage Biomarkers s-Coll2-1 and s-Coll2-1NO2 Are Associated with Knee Osteoarthritis MRI Features and Predict Disease Worsening
Yves Henrotin¹, Anne-Christine Hick², Berenice Costes³, Alain Labasse³, Thierry Conrozier⁴, Michel Malaise⁵, Yves Maugars⁶, Franz Pelousse⁷, Jean-Marc Lemaire⁸, Cedric Tits⁹, Thibault Helleputte⁹ and Damien Loeuille¹⁰, ¹University of Liège, Liège, Belgium, ²Artialis SA, Liège, Belgium, ³Artialis SA, Liege, Belgium, ⁴5. Department of Rheumatology, Hôpital Nord Franche-Comté, Belfort, France, ⁵University of Liège, Liege, Belgium, ⁶Service de rhumatologie, Hôtel-Dieu, CHU de Nantes, Nantes, France, ⁷SODIRAY, Solution Diagnostique Radiologique, Liège, Belgium, ⁸SODIRAY, Solution Diagnostique Radiologique, Liege, Belgium, ⁹Data-Driven Precision Medicine, DNAlytics, Louvain-la-Neuve, Belgium, ¹⁰CHU NANCY Rheumatology, NANCY
Background/Purpose: To identify if biochemical markers s-Coll2-1, a peptide of type collagen and its nitrated from, s-Coll2-1NO2 are associated to knee osteoarthritis (OA), focusing on…
Abstract Number: 1547 • ACR Convergence 2020
Role of Artificial Intelligence in Assessment of Peripheral Joint MRI in Inflammatory Arthritis: A Systematic Review and Meta-analysis
Arya Haj-Mirzaian¹, Olga Kubassova², Mikael Boesen³, Paul Bird⁴ and John Carrino⁵, ¹Johns Hopkins Hospital, Baltimore, MD, ²Image Analysis Group, London, United Kingdom, ³Department of Radiology Copenhagen University hospital Bispebjerg and Frederiksberg; The Parker Institute, Copenhagen, Denmark, ⁴Optimus Clinical Research, Kogarah, University of New South Wales, Sydney, New South Wales, Australia, ⁵Hospital for Special Surgery, Hackensack, NJ
Background/Purpose: To summarize the feasibility, reliability, and validity of computer-aided quantification of joint destruction and synovitis on MRI using artificial intelligence (AI) based methods in…
Abstract Number: 1113 • ACR Convergence 2020
Intrameniscal Signal Alterations Strongly Predict Destabilizing Meniscal Tears and Accelerated Knee Osteoarthritis: Data from the Osteoarthritis Initiative
Jeffrey Driban¹, James MacKay², Timothy McAlindon¹, Matthew Harkey³, Bing Lu⁴, Charles Eaton⁵, Grace Lo⁶, Mary Barbe⁷ and Robert Ward¹, ¹Tufts Medical Center, Boston, MA, ²University of Cambridge School of Clinical Medicine, Addenbrooke's Hospital; Norwich Medical School, University of East Anglia, Cambridge, United Kingdom, ³University of Massachusetts, Worcester, MA, ⁴Brigham and Women's Hospital and Harvard Medical School, Newton, MA, ⁵Brown University, Pawtucket, RI, ⁶Michael E. Debakey VA Medical Center, Baylor College of Medicine, Houston, TX, ⁷Temple University School of Medicine, Philadelphia, PA
Background/Purpose: It is unknown whether early changes in the menisci (e.g., intrameniscal signal alterations) have long-term consequences. We conducted a study to assess the prognostic…
Abstract Number: 1557 • ACR Convergence 2020
Lymphatics as a Biomarker of Joint Physiology: Near-Infrared Imaging of Indocyanine Green Identifies Novel Routes of Lymphatic Drainage from Metacarpophalangeal Joints in Healthy Human Hands
H. Mark Kenney¹, Gregory Dieudonne¹, Ronald Wood¹, Edward Schwarz¹, Christopher Ritchlin² and Homaira Rahimi³, ¹University of Rochester Medical Center, Rochester, ²Department of Medicine, University of Rochester Medical Center, Rochester, NY, ³University of Rochester Medical Center, Rochester, NY
Background/Purpose: In our previous work, we discovered that patients with active hand RA have reduced lymphatic drainage of indocyanine green (ICG) from the web spaces…
Abstract Number: 1114 • ACR Convergence 2020
Longitudinally Assessed Structural Abnormalities on MRI and Relative Contributions to Risk of Incident Radiographic Knee Osteoarthritis over 10 Years of Follow-up
C. Kent Kwoh¹, Ali Guermazi², Erin Ashbeck³, Chengcheng Hu³, Edward Bedrick³, Leena Sharma⁴, Charles Eaton⁵, Marc Hochberg⁶, Rebecca Jackson⁷, Timothy McAlindon⁸, Michael Nevitt⁹, Jane Cauley¹⁰ and Frank Roemer¹¹, ¹University of Arizona of Arizona Arthritis Center and Division of Rheumatology, College of Medicine, University of Arizona, Tucson, AZ, ²Boston University School of Medicine, Boston, MA, ³University of Arizona, Tucson, AZ, ⁴Northwestern University Feinberg School of Medicine, Chicago, IL, ⁵Department of Family Medicine and Epidemiology, Warren Alpert Medical School of Brown University,Department of Epidemiology, School of Public Health of Brown University, Providence, RI, ⁶University of Maryland School of Medicine, Baltimore, MD, ⁷Ohio State University, Columbus, OH, ⁸Tufts Medical Center, Boston, MA, ⁹University of California, San Francisco, San Francisco, CA, ¹⁰University of Pittsburgh, Pittsburgh, PA, ¹¹Boston University School of Medicine, Boston, MA, and Friedrich-Alexander University Erlangen-Nuremberg, Erlangen, Germany, Erlangen, Germany
Background/Purpose: MRI has identified joint tissues affected during knee OA development, though the relative importance of structures in the pathogenic process is unknown. Our objective…
Abstract Number: 1562 • ACR Convergence 2020
Subclinical Joint Inflammation of Hands by Magnetic Resonance Imaging in Patients with Psoriatic Arthritis in Clinical Remission Compared to Active Disease
Victoria Furer¹, Ari Polachek², David Levartovsky¹, Jonathan Wollman³, Mirna Zureik³, Daphna Paran¹, Hagit Sarbagil-Maman⁴, Sara Borok Lev-Ran¹, Mark Berman¹, Ilana Kaufman⁵, Adi Broide³, Valerie Aloush¹, Yael Lahat goldstein¹, Sharon Nevo³, Iris Eshed⁶ and Ori Elkayam³, ¹Tel Aviv Sourasky Medical Center, Tel Aviv, Israel, ²Tel Aviv Sourasky Medical Center, Petah-Tikva, Israel, ³Tel Aviv Sourasky Medical Center, Tel-Aviv, Israel, ⁴Tel-Aviv Sourasky Medical Center, Kiryat Ono, Israel, ⁵Tel Aviv Sourasky Medical Center, Petah-Tiqwa, Israel, ⁶Sheba Medical Center, Tel-Aviv, Israel
Background/Purpose: Assessment of disease activity in psoriatic arthritis (PsA) is based on tender and swollen joint counts (TJC and SJC, respectively). Yet, the prevalence of…
Abstract Number: 1115 • ACR Convergence 2020
The Relation of MRI-Based Cartilage Lesions to Knee Replacement and Knee Pain Severity in Osteoarthritis: The Multicenter Osteoarthritis Study
Tuhina Neogi¹, David Felson¹, Kathy Bacon², James Torner³, Cora Lewis⁴, Michael Nevitt⁵ and S. Reza Jafarzadeh¹, ¹Boston University School of Medicine, Boston, MA, ²Boston University School of Medicine, Boston, ³University of Iowa, Iowa City, IA, ⁴University of Alabama Birmingham, Birmingham, AL, ⁵University of California, San Francisco, San Francisco, CA
Background/Purpose: Recently, the FDA has indicated that data supporting imaging biomarkers of relevance to clinically important outcomes, such as knee replacement (KR) may be considered…
Abstract Number: 1713 • ACR Convergence 2020
Exploring Novel Tenosynovitis and Combined Inflammation Imaging Outcomes: Results from a Randomized Controlled Trial in Early Rheumatoid Arthritis
Philip G Conaghan¹, Mikkel Østergaard², Orrin Troum³, Zhiyong Xie⁴, Alan Brett⁵, Mark Snyder⁶, Abbas Ebrahim⁶, Douglass S Chapman⁷, Gosford A Sawyerr⁸ and John Andrews⁶, ¹Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and National Institute for Health Research Leeds Biomedical Research Centre, Leeds, United Kingdom, ²Rigshospitalet, University of Copenhagen, Copenhagen, Denmark, ³Division of Rheumatology, University of Southern California Keck School of Medicine, Santa Monica, CA, ⁴Pfizer Inc, Groton, CT, ⁵Imorphics Ltd, Manchester, United Kingdom, ⁶Pfizer Inc, Collegeville, PA, ⁷Pfizer Inc, New York, NY, ⁸Syneos Health, -
Background/Purpose: MRI trial outcomes have largely focused on synovitis, bone marrow edema (BME), and erosions. Tenosynovitis is a common manifestation of RA, but is relatively…
Abstract Number: 1116 • ACR Convergence 2020
Magnetic Resonance Imaging Structural Changes Correlated with Knee Extension: Data from the Osteoarthritis Initiative
T Mark Campbell¹, Guy Trudel² and Dennis McGonagle³, ¹Elisabeth Bruyère Hospital, Ottawa, ON, Canada, ²The Ottawa Hospital, Ottawa, ON, Canada, ³The University of Leeds, Leeds Institute for Rheumatic and Musculoskeletal Medicine, NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals Trust, Leeds, UK, Leeds, United Kingdom
Background/Purpose: Knee OA is often accompanied by loss of passive extension, termed a flexion contracture (FC), resulting in worse clinical outcomes. To our knowledge, MRI-based…
Abstract Number: 1719 • ACR Convergence 2020
Prevalence and Trajectory of Erosions, Synovitis, and Bone Marrow Edema in Feet of Patients with Early Rheumatoid Arthritis
Zechen Ma¹, Hanyan Zou², Mary-Clair Yelovich², Saara Totterman³, Karen Beattie² and Maggie Larche², ¹McMaster University, Mississauga, ON, Canada, ²McMaster University, Hamilton, ON, Canada, ³QMetrics Technologies, Rochester, NY
Background/Purpose: Imaging studies have shown that erosions emerge early in RA and is associated with worsening pain and function. Despite erosions being just as prevalent…
Abstract Number: 1117 • ACR Convergence 2020
Prediction Model for Progression to Different Find-Grained MRI-Based Osteoarthritis Severity States: The Vancouver Longitudinal Study of Early Knee Osteoarthritis (VALSEKO)
Jolanda Cibere¹, Ali Guermazi², Savvas Nicolaou³, Jacek Kopec⁴, John Esdaile⁵, Hubert Wong⁶, Joel Singer⁶, Anona Thorne⁶ and Eric Sayre⁷, ¹Arthritis Research Canada, University of British Columbia, Vancouver, BC, Canada, ²Boston University School of Medicine, Boston, MA, ³University of British Columbia, Vancouver, BC, Canada, ⁴University of British Columbia, Arthritis Research Canada, Richmond, BC, Canada, ⁵Arthritis Research Canada, Vancouver, BC, Canada, ⁶University of British Columbia, Vancouver, Canada, ⁷Arthritis Research Canada, Richmond, BC, Canada
Background/Purpose: To develop a novel, fine-grained MRI osteoarthritis (OA) severity score, based on cartilage, osteophytes and meniscus (OA-COM) scores and to predict the progression to…
Abstract Number: 1878 • ACR Convergence 2020
Consensus Definitions for MRI Lesions in the Spine of Patients with Axial Spondyloarthritis: First Analysis from the Assessments in SpondyloArthritis International Society Classification Cohort
Walter Maksymowych¹, Iris Eshed², Pedro M Machado³, Susanne J Pedersen⁴, Ulrich Weber⁵, Manouk de Hooge⁶, Joachim Sieper⁷, Stephanie Wichuk¹, Denis Poddubnyy⁸, Martin Rudwaleit⁹, Désirée van der Heijde¹⁰, Robert Landewé¹¹, Robert G Lambert¹², Mikkel Østergaard¹³ and Xenofon Baraliakos¹⁴, ¹University of Alberta, Edmonton, AB, Canada, ²Sheba Medical Center, Tel-Aviv, Israel, ³University College London, London, United Kingdom, ⁴Rigshospitalet University, Copenhagen, Denmark, ⁵University of South Denmark, Odense, Denmark, ⁶Ghent University Hospital, Ghent, Belgium, ⁷Charité Universitätsmedizin Berlin, Berlin, Germany, ⁸Charité – Universitätsmedizin Berlin, Berlin, Germany, ⁹Department of Internal Medicine and Rheumatology, Klinikum Bielefeld, Germany, ¹⁰Leiden University Medical Center, Leiden, Netherlands, ¹¹Amsterdam University Medical Center & Zuyderland Hospital, Amsterdam, Netherlands, ¹²University of Alberta and CARE Arthritis, Edmonton, AB, Canada, ¹³Rigshospitalet, University of Copenhagen, Copenhagen, Denmark, ¹⁴Rheumazentrum Ruhrgebiet Herne, Ruhr-University Bochum, Bochum, Germany
Background/Purpose: A broad spectrum of MRI lesions has been described in the spine of patients with axial spondyloarthritis (axSpA) and a recent consensus from the…
Abstract Number: 1118 • ACR Convergence 2020
Bone Marrow Lesion Scores in Patients with Knee Osteoarthritis Undergoing Tibial Osteotomy: Reliability and Concurrent Validity of the Knee Inflammation MRI Scoring System (KIMRISS)
Jenna Schulz¹, Trevor Birmingham¹, Walter Maksymowych², Robert G Lambert³, Stephany Pritchett⁴, Frank Beier¹, J. Robert Giffin⁵ and Tom Appleton⁶, ¹Western University, London, Canada, ²University of Alberta, Edmonton, AB, Canada, ³University of Alberta and CARE Arthritis, Edmonton, AB, Canada, ⁴London Health Sciences Centre, London, Canada, ⁵Western University and London Health Sciences Centre, London, Canada, ⁶The University of Western Ontario, LONDON, ON, Canada
Background/Purpose: Bone marrow lesions (BMLs) commonly occur in knee osteoarthritis (OA) and are associated with increased risk of cartilage damage and pain. The Knee Inflammation…
Abstract Number: 1879 • ACR Convergence 2020
Development of a Deep Learning Algorithm to Predict Positive MRI of the Sacroiliac Joints According to the ASAS Definition in Patients with Recent Axial Spondyloarthritis
Théodore Aouad¹, Clementina Lopez-Medina², Anna Molto², Antoine Feydy³, Charlotte Martin-Peltier³, Hugues Talbot⁴ and Maxime Dougados⁵, ¹Université Paris-Saclay, CentraleSupelec, Inria, Gif-Sur-Yvette, France, ²Rheumatology Department, Cochin Hospital, Paris, Paris, France, ³Radiology Department, Cochin Hospital, Paris, France, ⁴CVN, CentraleSupelec, Paris, France, ⁵Department of Rheumatology, Hopital Cochin, Université de Paris, Paris, France
Background/Purpose: The magnetic resonance imaging (MRI) of the sacroiliac joints (MRI-SIJ) represents an essential tool in the evaluation of patients with spondyloarthritis (SpA). However, despite…
Abstract Number: 1251 • ACR Convergence 2020
Assessing the Construct Validity of the Novel OMERACT Ultrasound Scoring System for Salivary Glands Target Lesions by Comparison with MRI in Patients with Sjögren’s Syndrome – An OMERACT Ultrasound Working Group Exercise
Nevsun Inanc¹, Sandrine Jousse-Joulin², Kerem Abacar³, Çagatay Cimşit⁴, Canan Cimşit⁴, Maria D’Agostino⁵, Esperanza Naredo⁶, Alojzija Hocevar⁷, Stephanie Finzel⁸, Lene Terslev⁹, Annamaria Iagnocco¹⁰, Petra Hanova¹¹, Wolfgang Schmidt¹², Gonca Mumcu¹³ and George A. Bruyn¹⁴, ¹Marmara University, School of Medicine, Division of Rheumatology, istanbul, Turkey, ²Rheumatology Department, Cavale Blanche Hospital and Brest Occidentale University, Brest, France, ³Marmara University, School of Medicine, Division of Rheumatology, Istanbul, Turkey, ⁴Marmara University School of Medicine, Radiology, Istanbul, Istanbul, Turkey, ⁵Université Versailles Saint Quentin, Ambroise Paré Hospital, Paris, France, ⁶Department of Rheumatology, Joint and Bone Research Unit. Hospital Universitario Fundación Jiménez Díaz, IIS Fundación Jiménez Díaz and Universidad Autónoma de Madrid, Madrid, Spain, ⁷University Medical Center, Rheumatology, Ljubljana, LJUBLJANA, Slovenia, ⁸Universitätsklinikum Freiburg, Klinik für Rheumatologie und Klinische Immunologie, Freiburg, Germany, ⁹Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Glostrup., Copenhagen, Denmark, ¹⁰Università degli Studi di Torino, Academic Rheumatology Centre, Turin, Italy, ¹¹Institute of Rheumatology, Prague, Czech Republic, Prague, Czech Republic, ¹²Immanuel Krankenhaus Berlin, Medical Center for Rheumatology Berlin-Buch, Berlin, Germany, ¹³Marmara University School of Health Sciences, Health Management, Istanbul, Istanbul, Turkey, ¹⁴Rheumatology, Reumakliniek Lelystad, Lelystad, Netherlands
Background/Purpose: Imaging techniques such as salivary gland ultrasound and magnetic resonance imaging (MRI) are able to diagnose primary Sjögren syndrome (pSS) patients with high sensitivity…

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