Abstracts tagged "Magnetic resonance imaging (MRI)"

Abstract Number: 0155 • ACR Convergence 2021
The Additional Value of MRI in Diagnosis of Rheumatoid Arthritis in Undifferentiated Arthritis Patients
Nikolet den Hollander¹, Marloes Verstappen¹, Navkiran Sidhu¹, Elise van Mulligen², Monique Reijnierse¹ and Annette H.M van der Helm-van Mil¹, ¹Leiden University Medical Center, Leiden, Netherlands, ²Erasmus Medical Center, Rotterdam, Netherlands
Background/Purpose: Identifying patients that will develop rheumatoid arthritis (RA) among those presenting with undifferentiated arthritis (UA) remains a clinical dilemma. According to EULAR recommendations magnetic…
Abstract Number: 0456 • ACR Convergence 2021
Functional Connectivity, Enhanced Blood-Brain Barrier Leakage and Cognitive Impairment in Systemic Lupus Erythematosus
John Hanly¹, Jason Robertson¹, Lyna Kamintsky¹, Alon Friedman¹, Steven Beyea¹, John Fisk¹, Antonina Omisade¹, Cindy Calkin¹, Tim Bardouille¹, Chris Bowen¹, Alexandra Legge¹, Arnold Mitnitski², Kara Matheson² and Javeria Hashmi¹, ¹Dalhousie University, Halifax, NS, Canada, ²Nova Scotia Health Authority, Halifax, NS, Canada
Background/Purpose: Cognitive impairment is the most frequent manifestation of neuropsychiatric systemic lupus erythematosus (NPSLE), yet the mechanisms underlying it remain poorly understood. We have previously…
Abstract Number: 1474 • ACR Convergence 2021
Automatic Detection of Bone Marrow Lesions from Knee MRI Data from the OAI Study
Shen Liu¹, Xiaoxiao Sun¹, Frank Roemer², Erin Ashbeck³, Edward Bedrick¹, Zong-Ming Li¹, Ali Guermazi⁴ and Kent Kwoh¹, ¹University of Arizona, Tucson, AZ, ²Friedrich-Alexander University Erlangen-Nurnberg, Erlangen, Germany, ³University of Arizona Arthritis Center, Tucson, AZ, ⁴Boston University, Boston, MA
Background/Purpose: Subchondral bone marrow lesions (BMLs) are associated with symptoms and structural progression of knee OA. BMLs are characterized by diffuse hyperintensity on fat suppressed…
Abstract Number: 0157 • ACR Convergence 2021
Development of a Deep Learning Algorithm for the Detection of Sacroiliitis on MRI in Patients with Active Axial Spondyloarthritis
Joeri Nicolaes¹, Pedro Machado², Xenofon Baraliakos³, Mayank Santosh⁴, Andrew Carnell⁴, Natasha de Peyrecave⁴ and Alexander Bennett⁵, ¹UCB Pharma, Brussels, Belgium; Medical Image Computing, ESAT-PSI, Department of Electrical Engineering, KU Leuven, Leuven, Belgium, ²Centre for Rheumatology & Department of Neuromuscular Diseases, University College London, London, United Kingdom, ³Rheumazentrum Ruhrgebiet Herne, Ruhr-Universität Bochum, Herne, Germany, ⁴UCB Pharma, Brussels, Belgium, ⁵Academic Department of Military Rehabilitation, Defence Medical Rehabilitation Centre Headley Court, Epsom, UK; National Heart and Lung Institute, Faculty of Medicine, Imperial College London, London, United Kingdom
Background/Purpose: Magnetic resonance imaging (MRI) plays a critical role in assisting the diagnosis of axial spondyloarthritis (axSpA). There are many characteristic MRI lesions that can…
Abstract Number: 0468 • ACR Convergence 2021
During Development of Rheumatoid Arthritis, Intermetatarsal Bursitis May Occur Before Clinical Joint Swelling: A Large MRI Study in Patients with Clinically Suspect Arthralgia
Bastiaan van Dijk¹, Fenne Wouters¹, Elise van Mulligen², Monique Reijnierse¹ and Annette H.M van der Helm-van Mil¹, ¹Leiden University Medical Center, Leiden, Netherlands, ²Erasmus Medical Center, Rotterdam, Netherlands
Background/Purpose: Inflammation of the synovial lining is a hallmark of rheumatoid arthritis (RA). A synovial lining is not only present at synovial joints and tendon…
Abstract Number: 1864 • ACR Convergence 2021
18F-Fluorodeoxyglucose PET/MRI as an Alternative Hybrid Imaging Modality: Comparative Study in a Prospective, Longitudinal Cohort of Patients with Large-Vessel Vasculitis
Ertugrul Cagri bolek¹, Kaitlin Quinn², Hugh Alessi³, Elaine Novakovich⁴, Mark A. Ahlman⁴ and Peter Grayson⁵, ¹Vasculitis Translational Research Program, NIAMS, NIH, US, Lanham, MD, ²National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Institutes of Health (NIH), Washington, DC, ³National Institutes of Health, Bethesda, Maryland, ⁴National Institutes of Health, Bethesda, MD, ⁵National Institutes of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Institutes of Health (NIH), Bethesda, MD
Background/Purpose: Imaging modalities play an important role in the diagnosis and management of patients with large-vessel vasculitis (LVV). Use of 18F-fluorodeoxyglucose (FDG) positron emission tomography…
Abstract Number: 0158 • ACR Convergence 2021
The Influence of Age on the Prevalence of Inflammatory and Post-inflammatory MRI Lesions in the Sacroiliac Joints of Patients with and Without Axial Spondyloarthritis
Xenofon Baraliakos, Styliani Tsiami, Anna Kühn, Martin Fruth and Jürgen Braun, Rheumazentrum Ruhrgebiet Herne, Ruhr-Universität Bochum, Herne, Germany
Background/Purpose: Axial spondyloarthritis (axSpA) is clinically characterized by chronic inflammatory back pain and by inflammatory and structural changes in the sacroiliac joint (SIJ) as assessed…
Abstract Number: 0469 • ACR Convergence 2021
Imaging Characteristics in Patients with Spondyloarthritis Using a Novel Heel Enthesitis Magnetic Resonance Imaging Scoring (HEMRIS) System: Post-hoc Analysis of a Phase 3 Secukinumab Trial
Xenofon Baraliakos¹, Philipp Sewerin², Eugenio De Miguel³, Effie Pournara⁴, Christine Kleinmond⁵, Ankita Shekhawat⁶, Annette Wiedon⁷ and Frank Behrens⁸, ¹Rheumazentrum Ruhrgebiet Herne, Ruhr-Universität Bochum, Herne, Germany, ²Department and Hiller Research Unit of Rheumatology, Heinrich Heine University Duesseldorf, Duesseldorf, Germany, ³Hospital Universitario La Paz, Madrid, Spain, ⁴Novartis Pharma AG, Basel, Switzerland, ⁵ClinProject GmbH, Eurasburg, Germany, ⁶Novartis Healthcare Private Limited, Hyderabad, India, ⁷Novartis Pharma GmbH, Nürnberg, Germany, ⁸Rheumatology & Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Fraunhofer Cluster Immune-Mediated Diseases (CIMD), Fraunhofer Cluster Immune-Mediated Diseases (CIMD), Frankfurt/Main, Germany
Background/Purpose: The heel is a frequently affected anatomical site for enthesitis in spondyloarthritis (SpA).1 Recently, the Outcome Measures in Rheumatology (OMERACT) group developed and validated…
Abstract Number: 1921 • ACR Convergence 2021
Axial Psoriatic Arthritis: Correlation Between Whole Spine MRI Abnormalities and Clinical Findings
Pamela Diaz¹, Iris Eshed², Joy Feld³ and Lihi Eder¹, ¹University of Toronto, Toronto, ON, Canada, ²Sheba Medical Center, Ramat Gan, Israel, ³Carmel and Zvulun Medical Centre, Haifa, Israel
Background/Purpose: Psoriatic Arthritis (PsA) typically affects peripheral joints, but in some patients the disease can involve the spine. While magnetic resonance imaging (MRI) is an…
Abstract Number: 0161 • ACR Convergence 2021
Does 18F-FDG-PET/MRI Add Metabolic Information to Anatomic Image in Childhood-onset Takayasu’s Arteritis Patients? A Multicenter Case Series
Gleice Clemente¹, Alexandre Souza², Hilton Leão Filho³, Fernando Coelho³, Carlos Buchpiguel⁴, Marcos Lima⁴, Daniela Petry Pioto⁵, Melissa Fraga¹, Ana Paula Sakamoto⁶, Camila Carneiro⁴, Rosa Pereira⁷, Nadia Aikawa⁷, Clovis Artur Silva⁷, Lucia Campos⁸, Camilla Astley⁹, Bruno Gualano¹⁰ and Maria Terreri¹¹, ¹Universidade Federal de São Paulo, São Paulo, Brazil, ²UNIFESP-EPM, São Paulo, Brazil, ³Universidade de Sao Paulo/Radiology Institute, São Paulo, Brazil, ⁴Universidade de São Paulo/Department of Radiology and Oncology, São Paulo, Brazil, ⁵Pediatric Rheumatology Unit, Universidade Federal de São Paulo, São Paulo, SP, Brazil, ⁶Federal University of So Paulo (UNIFESP), São Paulo, Brazil, ⁷Hospital das Clinicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, ⁸children's institute, Sao Paulo, Brazil, ⁹University of Sao Paulo, Sao Paulo, Brazil, ¹⁰Universidade de Sao Paulo/Rheumatology Division, São Paulo, Brazil, ¹¹UNIFESP, São Paulo, Brazil
Background/Purpose: The disease activity assessment in c-TA is a challenge in clinical practice, especially in patients who are under immunosuppression. Our aim was to perform…
Abstract Number: 0710 • ACR Convergence 2021
Patients with Recent Onset, Active Polymyositis (PM), Dermatomyositis (DM) and Antisynthetase Syndrome (ASS) Have Reduced Muscle Endurance but Not Reduced Muscle Strength Compared to Patients with Established, Low-active Disease
Kristofer Andreasson¹ and Helene Alexanderson², ¹Karolinska Institute, Stockholm, Sweden, ²Karolinska Institutet, Stockholm, Sweden
Background/Purpose: To analyze for differences in quadriceps maximal isometric voluntary contraction (MVIC), muscle endurance (ME), muscle mass and fat mass (m. vastus lateralis, mid-thigh) in…
Abstract Number: 0162 • ACR Convergence 2021
Cardiac Magnetic Resonance Imaging for Guiding Decision-making on Treatment Duration: Data from RHAPSODY, a Phase 3 Clinical Trial of Rilonacept in Recurrent Pericarditis
Paul Cremer¹, David Lin², Alistair Wheeler³, Antonio Abbate⁴, Antonio Brucato⁵, Fang Fang⁶, Antonella Insalaco⁷, Martin LeWinter⁸, Basil S. Lewis⁹, Sushil A. Luis¹⁰, Stephen J. Nicholls¹¹, John Petersen¹², Allan Klein¹, Massimo Imazio¹³ and John F Paolini⁶, ¹Department of Cardiovascular Imaging, Center for the Diagnosis and Treatment of Pericardial Diseases, Heart and Vascular Institute, Cleveland Clinic, Cleveland, OH, ²Minneapolis Heart Institute at Abbott Northwestern Hospital, Minneapolis, MN, ³Kiniksa Pharmaceuticals, Ltd., Hamilton, Bermuda, ⁴VCU Pauley Heart Center, Virginia Commonwealth University, Richmond, VA, ⁵Department of Biomedical and Clinical Science, University of Milano, Fatebenefratelli Hospital, Milan, Italy, ⁶Kiniksa Pharmaceuticals Corp., Lexington, MA, ⁷Department of Pediatric Medicine, Division of Rheumatology, Bambino Gesù Children's Hospital, Rome, Italy, ⁸Cardiology Unit, The University of Vermont Medical Center, The University of Vermont, Burlington, VT, ⁹Cardiovascular Clinical Research Institute, Lady Davis Carmel Medical Center, Haifa, Israel, ¹⁰Division of Cardiovascular Ultrasound, Department of Cardiovascular Medicine, Mayo Clinic, Rochester, NY, ¹¹MonashHeart, Department of Cardiology, Monash University, Clayton, Australia, ¹²Swedish Medical Center, Seattle, WA, ¹³University Cardiology, Cardiovascular and Thoracic Department, AOU Città della Salute e della Scienza di Torino, Torino, Italy
Background/Purpose: The magnitude of pericardial delayed hyperenhancement (DHE) by cardiac magnetic resonance imaging (CMR) illustrates the severity of inflammation in pericarditis. We hypothesized that patients…
Abstract Number: 0852 • ACR Convergence 2021
Bone Marrow Lesion Segmentation Using Synthetic Data and Deep Learning Models
Barak Michaely¹, Ming Zhang² and Juan Shan¹, ¹Pace University, New York, NY, ²Wentworth Institute of Technology, Boston, MA
Background/Purpose: Bone marrow lesions (BML) are indicators for knee osteoarthritis (OA) and can be detected from magnetic resonance imaging (MRI). Due to the small size,…
Abstract Number: 0181 • ACR Convergence 2021
Magnetic Resonance Imaging Findings in Early Rheumatoid Arthritis: Are There Differences Based on Autoantibody Status?
Caitrin Coffey¹, Gavin McKenzie¹, Nicholas Rhodes¹, Cassondra Hulshizer¹, Cynthia Crowson², John Davis¹ and Kerry Wright¹, ¹Mayo Clinic, Rochester, MN, ²Mayo Clinic, Eyota, MN
Background/Purpose: Magnetic resonance imaging (MRI) is increasingly used as an adjunct to the physical examination in early rheumatoid arthritis (RA). Characteristic differences in MRI findings…
Abstract Number: 0898 • ACR Convergence 2021
MRI Vertebral Corner Inflammation and Fat Deposition Are Associated with Whole Spine Low Dose CT Detected Syndesmophytes: A Multilevel Analysis
Rosalinde Stal¹, Xenofon Baraliakos², Alexandre Sepriano³, Floris van Gaalen¹, Sofia Ramiro¹, Rosaline van den Berg¹, Monique Reijnierse¹, Juergen Braun², Robert Landewé⁴ and Désirée van der Heijde⁵, ¹Leiden University Medical Center, Leiden, Netherlands, ²Rheumazentrum Ruhrgebiet Herne, Ruhr-Universität Bochum, Herne, Germany, ³Leiden University Medical Center, Lisbon, Portugal, ⁴Amsterdam Rheumatology & Clinical Immunology Center, Amsterdam, Netherlands; Zuyderland MC, Heerlen, Netherlands, ⁵Department of Rheumatology, Leiden University Medical Center, Meerssen, Netherlands
Background/Purpose: In previous studies vertebral corner inflammation (VCI) and vertebral corner fat deposition (VCFD) were associated with syndesmophyte formation on cervical and lumbar conventional radiography.…

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