Abstracts tagged "Lupus"

Abstract Number: 1168 • 2016 ACR/ARHP Annual Meeting
The Epidemiology of Individuals Not Fully Meeting Classification Criteria for Systemic Lupus Erythematosus (SLE): The Georgia Lupus Registry
Puja Saxena¹, Gaobin Bao², Cristina Drenkard³ and S. Sam Lim², ¹Rheumatology, Emory University School of Medicine, Atlanta, GA, ²Medicine, Emory University School of Medicine, Atlanta, GA, ³Emory University School of Medicine, Atlanta, GA
Background/Purpose: Identifying individuals as early as possible in the development of an autoimmune disease may lead to important opportunities. This study utilizes an established population-based…
Abstract Number: 1799 • 2016 ACR/ARHP Annual Meeting
Smoking, Antiphospholipid Antibodies and Thrombosis in SLE
Michelle Petri¹, George Stojan² and Wei Fu³, ¹Rheumatology Division, Johns Hopkins University School of Medicine, Baltimore, MD, ²Rheumatology, Johns Hopkins University, Baltimore, MD, ³Division of Rheumatology, School of Medicine, Johns Hopkins University, Baltimore, MD
Background/Purpose: Anticardiolipin Ever smoking 411 (48.1%) Past smoking 246 (49.8%) Current smoking 165 (46.6%) Never smoking 721 (48.9%) P Value (Ever vs. Never) 0.6943…
Abstract Number: 2821 • 2016 ACR/ARHP Annual Meeting
Is Hyperuricemia an Independent Risk Factor for Arterial Thrombosis in Systemic Lupus Erythematosus?
Chi Chiu Mok¹, Ling Yin Ho², Chi Hung To³ and Kar Li Chan¹, ¹Medicine, Tuen Mun Hospital, Hong Kong, Hong Kong, ²Dept of Medicine, Tuen Mun Hospital, Hong Kong SAR, Hong Kong, ³Medicine, Pok Oi Hospital, Hong Kong, Hong Kong
Background/Purpose: To evaluate whether hyperuricemia is independently associated with cardiovascular events in a cross-sectional study of Chinese patients with SLE. Methods: Consecutive patients who fulfilled…
Abstract Number: 1169 • 2016 ACR/ARHP Annual Meeting
A Systematic Review of Rheumatic Disease Epidemiology in the Indigenous Populations of Canada, the United States, Australia and New Zealand
Cairistin McDougall¹, Kelle Hurd¹ and Cheryl Barnabe², ¹University of Calgary, Calgary, AB, Canada, ²Division of Rheumatology, University of Calgary, Calgary, AB, Canada
Background/Purpose: Two important reviews have summarized the epidemiology of rheumatic disease (Peschken 1999) and RA (Ferucci 2005) in Indigenous populations of North America. Our objective…
Abstract Number: 1819 • 2016 ACR/ARHP Annual Meeting
Myocarditis in Systemic Lupus Erythematosus
Alexandra Perel-Winkler¹, Sabahat Bokhari², Anca D. Askanase³ and Laura Geraldino-Pardilla⁴, ¹Rheumatology, Columbia University College of Physicians & Surgeons, New York, NY, ²Cardiology, Columbia University College of Physicians & Surgeons, NY, NY, ³Department of Medicine, Rheumatology, Columbia University College of Physicians & Surgeons, New York, NY, ⁴Columbia University College of Physicians & Surgeons, new york, NY
Background/Purpose : Cardiovascular disease (CVD) is a leading cause of death in patients with SLE. Lupus patients have a 2-3 fold increased risk of heart…
Abstract Number: 2832 • 2016 ACR/ARHP Annual Meeting
Novel Gene Variants Associated with Cardiovascular Disease in Systemic Lupus Erythematosus
Dag Leonard¹, Andrei Alexsson¹, Johanna Dahlqvist², Kimberly Taylor³, Johanna K Sandling⁴, Christine Bengtsson⁵, Elisabet Svenungsson⁶, Christopher Sjöwall⁷, Andreas Jönsen⁸, Iva Gunnarsson⁶, Anders A. Bengtsson⁸, Solbritt Rantapaa-Dahlqvist⁵, Maija-Leena Eloranta¹, Ann-Christine Syvänen⁴, Lindsey A. Criswell⁹ and Lars Rönnblom¹, ¹Uppsala University, Department of Medical Sciences, Rheumatology and Science for Life Laboratory, Uppsala, Sweden, ²Uppsala University, Department of Medical Biochemistry and Microbiology Science for Life Laboratory, Uppsala, Sweden, ³University of California, San Francisco, Rosalind Russell / Ephraim P. Engleman Rheumatology Research Center, San Francisco, CA, ⁴Uppsala University, Department of Medical Sciences, Molecular Medicine and Science for Life Laboratory, Uppsala, Sweden, ⁵Umeå University, Department of Public Health and Clinical Medicine/ Rheumatology, Umeå, Sweden, ⁶Karolinska Institutet, Department of Medicine, Unit of Rheumatology, Stockholm, Sweden, ⁷Linköping University, Department of Clinical and Experimental Medicine Rheumatology/AIR, Linköping, Sweden, ⁸Lund University, Department of Clinical Sciences, Rheumatology, Lund, Sweden, ⁹Medicine, University of California, San Francisco, Rosalind Russell / Ephraim P. Engleman Rheumatology Research Center, San Francisco, CA
Background/Purpose: Methods: An association between a locus located on chromosome 14 and stroke/TIA was shown in both the Swedish (OR 1.8, p=0.0002) and the US…
Abstract Number: 1171 • 2016 ACR/ARHP Annual Meeting
Obesity and the Risk of Systemic Lupus Erythematosus in the Nurses’ Health Studies
Sara K. Tedeschi¹, Medha Barbhaiya¹, Bing Lu¹, Susan Malspeis², Jeffrey A. Sparks², Elizabeth W. Karlson¹, Walter C. Willett³ and Karen H. Costenbader¹, ¹Rheumatology, Immunology and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, ²Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, ³Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA
Background/Purpose: Obesity has become alarmingly common over the past four decades in the U.S., with a notable rise in obesity prevalence starting in the late…
Abstract Number: 1821 • 2016 ACR/ARHP Annual Meeting
Demethylated CD4+CD28+KIR+CD11ahi T Cells Are Characterized By a Pro-Inflammatory Transcriptome and Interact with Genetic Risk to Predict Disease Activity in Lupus
Paul Renauer¹, Patrick Coit¹, Faith Strickland², Elizabeth Gensterblum¹, Mikhail Ognenovski¹, Bruce Richardson³ and Amr Sawalha⁴, ¹Division of Rheumatology, University of Michigan, Ann Arbor, MI, ²Rheumatology, University of Michigan, Ann Arbor, MI, ³Rheumatology, University of Michigan and the Ann Arbor VA, Ann Arbor, MI, ⁴Internal Medicine-Rheumatology, University of Michigan, Ann Arbor, MI
Background/Purpose: T cell DNA methylation defects play an important role in the pathogenesis of systemic lupus erythematosus. A CD4+CD28+ T cell subset characterized by overexpression…
Abstract Number: 2848 • 2016 ACR/ARHP Annual Meeting
Near Patient Anti-Nuclear Antibody Multiplex Testing Using Whole Blood for the Diagnosis of Connective Tissue Diseases in a Tertiary Care Center
Makoto Miyara¹, Jean- Luc Charuel², Sasi Mudumba³, Alice Wu³, Pascale Ghillani-Dalbin², Zahir Amoura^4,5,6, Rufus Burlingame⁷ and Lucile Musset¹, ¹Department of immunology, Pitié-Salpêtrière Hospital (AP-HP), Paris, France, ²Department of Immunology, Pitié-Salpêtrière Hospital (AP-HP), Paris, France, ³Genalyte, Inc., San Diego, CA, ⁴Internal Medecine - Centre de Référence National pour les Lupus et et le Syndrome des Antiphospholipides, Internal Medecine - Centre de Référence National pour les Lupus et et le Syndrome des Antiphospholipides, Pitié-Salpêtrière Hospital (AP-HP), Paris, France, ⁵Department of Internal Medicine 2. Referal center for SLE/APS, Pitié-Salpêtrière Hospital (AP-HP), Paris, France, ⁶Internal medicine 2, French National Reference Center for Systemic Lupus and Antiphospholipid Syndrome, Pitié-Salpêtrière Hospital (AP-HP), Paris, France, ⁷Genaltye, San Diego, CA
Background/Purpose: Detection of anti-nuclear antibodies for the diagnosis of connective tissue diseases (CTD) often requires complex algorithms to obtain conclusive results , including immunofluorescence on…
Abstract Number: 123 • 2016 ACR/ARHP Annual Meeting
A Panel of Urinary Biomarkers to Assess Renal Involvement in Latin American Patients with Systemic Lupus Erythematosus
José A. Gómez-Puerta^1,2, Blanca L Ortiz Reyes¹, Tomás Urrego¹, Adriana L Vanegas^2,3, Carlos Horacio Muñoz^3,4, Mauricio Restrepo², Wilmer Rojas-Zuleta², Sofia Arteaga², Luis Alonso Gonzalez⁴ and Gloria Vásquez^1,4, ¹Grupo de Inmunología Celular e Inmunogenética, Universidad de Antioquia, Medellín, Colombia, ²Rheumatology Unit, Universidad de Antioquia, Medellín, Colombia, ³Hospital Universitario de San Vicente Fundación, Medellín, Colombia, ⁴Rheumatology Unit, Universidad de Antioquia, Medellin, Colombia
Background/Purpose: Some previous studies in Caucasian, Asian, and African-american patients have shown promising results for several urinary biomarkers in patients with lupus nephritis (LN). However,…
Abstract Number: 1174 • 2016 ACR/ARHP Annual Meeting
Perceived Stress and Reported Cognitive Symptoms Among Patients with Systemic Lupus Erythematosus
Laura Plantinga¹, Cristina Drenkard², C. Barrett Bowling¹ and S. Sam Lim³, ¹Department of Medicine, Emory University, Atlanta, GA, ²Department of Medicine, Emory University School of Medicine, Atlanta, GA, ³Medicine, Emory University School of Medicine, Atlanta, GA
Background/Purpose: Higher stress is associated with lower cognitive functioning in many populations. We examined associations of perceived stress with cognitive symptoms among adults with systemic…
Abstract Number: 1834 • 2016 ACR/ARHP Annual Meeting
Commensal Ro60 Autoantigen Ortholog Cross-Reactivity in Human Lupus and Gnotobiotic Models
Teri Greiling¹, Carina Dehner², Stephen Renfroe³, Xinguo Chen⁴, Kevin Hughes⁴, Silvio M. Vieira³, William Ruff³, Marco Boccitto⁴, Andrew Goodman⁵, Sandra L. Wolin⁴ and Martin Kriegel^3,6, ¹Dermatology and Immunobiology, Yale School of Medicine, New Haven, CT, ²Immunobiology, Yale School of Medicine, new haven, CT, ³Immunobiology, Yale School of Medicine, New Haven, CT, ⁴Cell Biology, Yale School of Medicine, New Haven, CT, ⁵Microbial Pathogenesis, Yale School of Medicine, New Haven, CT, ⁶Medicine/Division of Rheumatology, Yale School of Medicine, New Haven, CT
Background/Purpose: The earliest autoantibodies in lupus are directed against the autoantigen Ro60, an RNA binding protein with orthologs that we identified in a subset of…
Abstract Number: 2849 • 2016 ACR/ARHP Annual Meeting
Systemic Lupus Erythematosus Patients with Antibodies Against U1-Ribonucleoprotein Exhibit a Specific Pattern of Disease Manifestations
David Fernandez¹, Mikhail Olferiev¹, Leila Khalili¹, Kyriakos A. Kirou² and Mary K. Crow¹, ¹Mary Kirkland Center for Lupus Research, Hospital for Special Surgery, New York, NY, ²Rheumatology, Hospital for Special Surgery, New York, NY
Background/Purpose: Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by the production of autoantibodies against nucleic acids and a variety of self-antigens. Recent work…
Abstract Number: 401 • 2015 ACR/ARHP Annual Meeting
Racial and Ethnic Disparities in Depression Diagnosis and Treatment for Adolescents with SLE: Analysis of a National Medicaid Sample
Andrea Knight¹, Ming Xie² and David Mandell³, ¹Pediatrics/Rheumatology, Children's Hospital of Philadelphia, Philadelphia, PA, ²University of Pennsylvania, Center for Mental Health Policy and Services Research, Philadelphia, PA, ³Psychiatry and Pediatrics, University of Pennsylvania, Center for Mental Health Policy and Services Research, Philadelphia, PA
Background/Purpose: Adolescents with systemic lupus erythematosus (SLE) are at high risk for depression. Racial/ethnic minorities are disproportionately affected by SLE, and previous studies suggest a…
Abstract Number: 806 • 2015 ACR/ARHP Annual Meeting
STAT1 Activation Promotes TLR8 Overexpression and Facilitates Mirokine Signaling Via Exosomes Containing a Mir-21 Endogenous Ligand: A Novel Innate Inflammatory Pathway in Systemic Lupus Erythematosus
Giancarlo R. Valiente^1,2, Nicholas A. Young², Lai-Chu Wu^3,4, Jeffrey Hampton⁵, Mary Severin⁶, Amy Lovett-Racke⁶ and Wael N. Jarjour⁷, ¹Medical Scientist Training Program, The Ohio State University College of Medicine, Columbus, OH, ²Rheumatology & Immunology, The Ohio State University Wexner Medical Center, Columbus, OH, ³Immunology and Rheumatology, The Ohio State University Wexner Medical Center, Columbus, OH, ⁴Biological Chemistry and Pharmacology, The Ohio State University College of Medicine, Columbus, OH, ⁵Immunology and Rheumatoloty, The Ohio State University Wexner Medical Center, Columbus, OH, ⁶Microbial Infection and Immunity, The Ohio State University College of Medicine, Columbus, OH, ⁷Dept of Rheumatology/Medicine, The Ohio State University Wexner Medical Center, Columbus, OH
Background/Purpose: The adaptive arm of the immune system plays a significant role in the pathophysiology of Systemic Lupus Erythematosus (SLE). However, recent studies suggest that…

All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

Violation of this policy may result in the abstract being withdrawn from the meeting and other measures deemed appropriate. Authors are responsible for notifying colleagues, institutions, communications firms, and all other stakeholders related to the development or promotion of the abstract about this policy. If you have questions about the ACR abstract embargo policy, please contact ACR abstracts staff at [email protected].