Abstracts tagged "Lupus"

Abstract Number: 689 • 2019 ACR/ARP Annual Meeting
Patterns of High Disease Activity Status and Outcomes in Systemic Lupus Erythematosus
Alberta Hoi ¹, Hieu Nim ², Rachel Koelmeyer ², Ying Sun ³, Amy Kao ⁴, Oliver Guenther ³ and Eric Morand², ¹School of Clinical Sciences, Monash University, Meloburne, Victoria, Australia, ²Monash University, Melbourne, Victoria, Australia, ³Merck Healthcare KGaA, Darmstadt, Germany, ⁴EMD Serono Research & Development Institute, Inc., Billerica, MA
Background/Purpose: High Disease Activity Status (HDAS), defined as ever attainment of SLEDAI-2k of 10 or greater, may be a useful indicator of overall disease severity in…
Abstract Number: 1199 • 2019 ACR/ARP Annual Meeting
Improving Rates of Cervical Cancer Screening and HPV Vaccination in Patients with Lupus
Nancy Desai¹, Hanni Menn-Josephy ¹, Ramon Bonegio ¹, Christina Lam ¹, Anna Kancharla ¹ and Michael York ¹, ¹Boston Medical Center, Boston
Background/Purpose: Patients with lupus have higher rates of cervical dysplasia and pre-malignant cervical lesions. At our institution, an urban referral center for patients with lupus, rates…
Abstract Number: 1734 • 2019 ACR/ARP Annual Meeting
Low Bone Mineral Density Was Associated with Lupus Nephritis Irrespective of Duration on Steroid Treatment in a Large Observational Study of Juvenile Systemic Lupus Erythematosus Patients
Anastasia-vasiliki Madenidou¹, Yasmin Mahfouz ², Oliver Cheng ², Farah El-Sharnouby ², Charlene Foley ² and Coziana Ciurtin ³, ¹Centre for Adolescent Rheumatology, University College London London, UK, LOndon, ²Centre for Adolescent Rheumatology, University College London London, UK, London, United Kingdom, ³Centre for Adolescent Rheumatology, University College London London, UK, Londond, United Kingdom
Background/Purpose: An estimated 10-20% of all patients with systemic lupus erythematosus (SLE) develop clinical disease before the age of 18 years and are therefore classified…
Abstract Number: 2584 • 2019 ACR/ARP Annual Meeting
Management of Cutaneous Manifestations of Lupus Erythematosus: A Systematic Review
Jessica Fairley¹, Shereen Oon ², Amanda Saracino ³ and Mandana Nikpour ², ¹Monash University, Melbourne, Australia, ²St Vincent's Hospital, Melbourne; The University of Melbourne, Melbourne, Australia, ³University College London, London, United Kingdom
Background/Purpose: Cutaneous lupus erythematosus (CLE), occurring with or without systemic lupus erythematosus (SLE), is a group of inflammatory skin diseases that can be very debilitating,…
Abstract Number: 691 • 2019 ACR/ARP Annual Meeting
Adjusted GAPSS in Systemic Lupus Erythematosus Patients in Argentina
Lucila Garcia¹, Maria Victoria Martire ¹, Sofia Velloso ¹, Florencia Savy ¹, Fernando Arizpe ², Nadia Garcia ¹, Adriana Testi ¹, Claudia Pena ¹, Dafne Capelusnik ³, Carolina Ayelen Isnardi ⁴, Victoria Collado ⁵, MARIA FLORENCIA Rodriguez ⁶, Cecilia Pisoni ⁷, Susana Mazza ⁸, Yessika Soria Curi ⁸, Adriana Seewald ⁹, María de la Torre ⁷ and Mercedes Garcia ¹⁰, ¹Hospital San Martin, La Plata, Argentina, ²Hospital San Martin, Buenos Aires, Argentina, ³Instituto de Rehabilitacion Psicofisica, CABA, Ciudad Autonoma de Buenos Aires, Argentina, ⁴Instituto de Rehabilitación Psicofísica, Ciudad de Buenos Aires, Ciudad Autonoma de Buenos Aires, Argentina, ⁵Private clinic, buenos aires, Argentina, ⁶hospital rivadavia, buenos aires, Argentina, ⁷Centro de Educación Médica e Investigaciones Clínicas Norberto Quirno (CEMIC), Ciudad Autónoma de Buenos Aires, Buenos Aires, Argentina, ⁸Hospital Ángel C. Padilla, San Miguel de Tucumán, Tucuman, Argentina, ⁹Hospital Escuela de Agudos Dr. Ramón Madariaga, Posadas, Argentina, ¹⁰Hospital San Martín, La Plata, Argentina
Background/Purpose: Assessment of risk both for pregnancy morbidity and thrombosis in the presence of anti-phospholipid antibodies (aPL) is still a challenge. The Global Antiphospholipid Syndrome…
Abstract Number: 1561 • 2019 ACR/ARP Annual Meeting
Decreased Nocturnal Blood Pressure Dipping in Patients with Systemic Lupus Erythematosus: Association with Markers of Inflammation
Daniel Carranza Leon¹, Annette Oeser ¹, Qiong Wu ¹, C. Michael Stein ², Michelle Ormseth ¹ and Cecilia Chung ², ¹Vanderbilt University Medical Center, Nashville, ²Vanderbilt University Medical Center, Nashville, TN
Background/Purpose: Blood pressure follows a circadian rhythm; usually systolic blood pressure (SBP) drops by more than 10% during the night. Absence of this phenomenon, known…
Abstract Number: 1786 • 2019 ACR/ARP Annual Meeting
Surrogate Pathways of Complement Activation in Novel Polygenic SLE-like Models of Kidney Injury
Sladjana Skopelja-Gardner¹, Xizhang Sun ², Yufeng Peng ², Lucrezia Colonna ², Payton Hermanson ², Lena Tanaka ², Joyce Tai ², David Salant ³ and Keith Elkon ², ¹University of Washington, Seattle, WA, ²University of Washington, Seattle, ³Boston University, Boston
Background/Purpose: Lupus nephritis (LN) is a major contributor to morbidity and mortality in systemic lupus erythematosus (SLE). Defective clearance of apoptotic cells (AC), autoantibodies, and…
Abstract Number: 2782 • 2019 ACR/ARP Annual Meeting
Comparative Risks of Cardiovascular Disease Among SLE Patients Receiving Immunosuppressive Medications
Daniel Li¹, Candace Feldman ¹, Hongshu Guan ¹, Brendan Everett ², Seoyoung C. Kim ³ and Karen Costenbader ², ¹Brigham and Women's Hospital, Boston, ²Brigham and Women's Hospital, Boston, MA, ³Brigham and Women’s Hospital and Harvard Medical School, Boston
Background/Purpose: Human studies examining cardiovascular disease (CVD) risk associated with immunosuppressants (IS) have been limited, but mycophenolate mofetil (MMF) was shown to suppress vascular smooth muscle…
Abstract Number: 694 • 2019 ACR/ARP Annual Meeting
Body Mass Index at Time of Diagnosis Is Predictive of Future Disease Activity in SLE
George Stojan¹, Jessica Li ² and Michelle Petri ², ¹Johns Hopkins University, Baltimore, MD, ²Johns Hopkins University School of Medicine, Baltimore, MD
Background/Purpose: Obesity is more common in patients with SLE compared to the general population. The prevalence of obesity among SLE patients is between 28 and…
Abstract Number: 1568 • 2019 ACR/ARP Annual Meeting
High Risk Low Attenuation Non-Calcified Coronary Plaque in Lupus vs. Controls
George Stojan¹, Jessica Li ² and Michelle Petri ², ¹Johns Hopkins University, Baltimore, MD, ²Johns Hopkins University School of Medicine, Baltimore, MD
Background/Purpose: The presence of low attenuation noncalcified plaque (< 30 Haunsfield units) is one of the most characteristic vessel changes in unstable coronary plaques. Low-attenuation…
Abstract Number: 1828 • 2019 ACR/ARP Annual Meeting
Avascular Necrosis Is Associated with APOL1 Variants in African Americans with Systemic Lupus Erythematosus
Kevin Yip¹, Elizaveta Efuni ², Yingzhi Qian ¹, Robert Clancy ³, Jill Buyon ² and Ashira Blazer ¹, ¹New York University School of Medicine, New York City, ²New York University School of Medicine, New York, NY, ³New York University School of Medicine, New York
Background/Purpose: African Americans (AA) with systemic lupus erythematous (SLE) are at higher risk for both renal disease and avascular necrosis (AVN). The two Apolipoprotein L1…
Abstract Number: 2868 • 2019 ACR/ARP Annual Meeting
Baseline Clinical and Serological Findings in Pediatric-Onset Discoid Lupus Erythematosus: Analysis of a Multicenter Retrospective Cohort Study
Nnenna Ezeh¹, Kevin Buhr², Cordellia Nguyen³, Ohoud Al Ahmed⁴, Stacy Ardoin⁵, Virginia Barton⁶, Samantha Bell⁷, Heather Brandling-Bennett⁸, Leslie Castelo-Soccio⁹, Yvonne Chiu¹⁰, Benjamin Chong¹¹, Dominic Co¹², Irene Lara-Corrales¹³, Amber Cintosun¹³, Lucia Diaz¹⁴, Scott Andrew Elman¹⁵, Esteban Fernandez Faith⁴, Maria Teresa Garcia-Romero¹⁶, Julie Grossman-Kranseler⁸, Aimee Hersh¹⁷, Marcia Hogeling¹⁸, Andrew Hudson¹⁹, Raegan Hunt²⁰, Erin Ibler¹⁰, Mariana Marques²¹, Reesa Monir²², Vikash Oza²³, Amy Paller²⁴, Elana Putterman⁹, Pamela Rodriguez-Salgado¹⁶, Jennifer Schoch²², Allison Truong¹⁸, Jason Wang²³, Lara Wine Lee⁶, Ruth Ann Vleugels¹⁵, Marisa Klein-Gitelman²⁵, Emily von-Scheven²⁶, Victoria Werth²⁷, Kaveh Ardalan²⁸and Lisa Arkin²⁹,¹University of Wisconsin School of Medicine and Public Health, Madison, WI,²Department of Biostatistics & Medical Informatics, University of Wisconsin School of Medicine and Public Health, Madison,³University of Wisconsin School of Medicine and Public Health, Madison,⁴Department of Pediatrics, Division of Dermatology, Nationwide Children's Hospital/Ohio State University, Columbus,⁵Nationwide Children's Hospital, Columbus, OH,⁶Department of Dermatology and Dermatologic Surgery, Medical University of South Carolina, Charleston,⁷Department of Pediatrics, Division of Rheumatology, University of California at San Francisco, San Francisco,⁸Division of Dermatology; Department of Pediatrics, Seattle Children's Hospital/University of Washington School of Medicine, Seattle,⁹Department of Pediatrics, Section of Dermatology, Children's Hospital of Philadelphia, Philadelphia,¹⁰Departments of Dermatology and Pediatrics, Medical College of Wisconsin, Milwaukee,¹¹University of Texas Southwestern, Dallas,¹²Department of Pediatrics, Division of Rheumatology, University of Wisconsin School of Medicine and Public Health, Madison,¹³Department of Pediatrics, Division of Dermatology, The Hospital for Sick Children/University of Toronto, Toronto, Canada,¹⁴Department of Pediatrics, Division of Dermatology, Dell Medical School/Dell Children's Hospital, Austin, Texas,¹⁵Department of Dermatology, Boston's Children Hospital/Harvard Medical School, Boston,¹⁶Department of Dermatology, National Institute for Pediatrics, Mexico City, Mexico,¹⁷University of Utah, Salt Lake City, UT,¹⁸Department of Dermatology, University of California at Los Angeles, Los Angeles,¹⁹Department of Dermatology, University of Texas Southwestern Medical Center, Dallas,²⁰Departments of Pediatrics and Dermatology, Texas Children's Hospital, Houston, Texas,²¹Division of Rheumatology, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago,²²Department of Dermatology, University of Florida School of Medicine, Gainesville,²³Departments of Pediatrics and Dermatology, New York University School of Medicine, New York,²⁴Departments of Dermatology and Pediatrics, Northwestern University Feinberg School of Medicine/Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago,²⁵Department of Pediatrics, Division of Rheumatology, Northwestern University Feinberg School of Medicine/Ann & Robert H. Lurie Children's Hospital, Chicago,²⁶University of California San Francisco, San Francisco,²⁷Corporal Michael J. Crescenz VAMC, Philadelphia, PA, USA and Department of Dermatology, University of Pennsylvania, Philadelphia, PA, USA, Philadelphia, PA,²⁸Division of Pediatric Rheumatology, Department of Pediatrics, Northwestern University, Chicago, Illinois,²⁹Department of Dermatology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin
Background/Purpose: DLE is a rare, disfiguring disorder in children. Small retrospective studies suggest 20-25% of patients progress to SLE. Progression risk factors are poorly understood,…
Abstract Number: 695 • 2019 ACR/ARP Annual Meeting
Environmental and Atmospheric Factors in Systemic Lupus Erythematosus: A Regression Analysis
George Stojan¹, Frank Curriero ², Anton Kvit ² and Michelle Petri ³, ¹Johns Hopkins University, Baltimore, MD, ²Johns Hopkins Bloomberg School of Public Health, Baltimore, ³Johns Hopkins University School of Medicine, Baltimore, MD
Background/Purpose: Understanding the role of environmental exposures in the development of SLE and their association with SLE activity may help identify modifiable risk factors and…
Abstract Number: 1583 • 2019 ACR/ARP Annual Meeting
Prognostic Value of Urinary Biomarkers for the Developing of End Stage Renal Disease in Patients with Systemic Lupus Erythematosus
Jose A Gómez-Puerta¹, Tomás Urrego ², Blanca Ortiz Reyes ³, Adriana Vanegas-García ⁴, Carlos H Muñoz-Vahos ⁴, Luis A González ⁴ and Gloria Vasquez ⁵, ¹Rheumatology Department, Hospital Clinic de Barcelona, Barcelona, Catalonia, Spain, ²Grupo de Inmunología Celular e Inmunogenética, Universidad de Antioquia, Medellín, Antioquia, Colombia, ³Grupo de Inmunología Celular e Inmunogenética, Facultad de Medicina, Universidad de Antioquia, Medellín, Antioquia, Colombia, ⁴Grupo de Reumatología, Universidad de Antioquia, Medellín, Antioquia, Colombia, ⁵University of Antioquia, Medellin, Antioquia, Colombia
Background/Purpose: Background: There is an increasing knowledge about the utility of urinary biomarkers for the diagnosis of lupus nephritis (LN) in patients with systemic lupus…
Abstract Number: 1843 • 2019 ACR/ARP Annual Meeting
Predictors of Mortality Among Black Women with Systemic Lupus Erythematosus: The Black Women’s Experiences Living with Lupus (BeWELL) Study
Charmayne Dunlop-Thomas¹, Gaobin Bao ², Cristina Drenkard ², David Chae ³ and S Sam Lim ², ¹Emory University, Atlanta, Georgia, ²Emory University, Atlanta, GA, ³Auburn University, Auburn, AL
Background/Purpose: Mortality continues to be disproportionately high in Black women with SLE living in the South region of the United States. Recent studies suggest that…

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