Abstracts tagged "Lupus"

Abstract Number: 2088 • 2016 ACR/ARHP Annual Meeting
Rituximab Use in Pediatric Lupus Anticoagulant Hypoprothrombinemia Syndrome – Report of Three Cases and Review of the Literature
Kader Cetin Gedik¹, Salma Siddique², Cassyanne L. Aguiar³ and Doruk Erkan⁴, ¹Pediatric Rheumatology, Cohen Children's Medical Center of New York/ Hofstra Northwell School of Medicine, Lake Success, NY, ²Hospital for Special Surgery- NewYork-Presbyterian / Weill Cornell Medical Center, New York, NY, ³Pediatric Rheumatology, Cohen Children's Medical Center / Hofstra Northwell School of Medicine, Lake Success, NY, ⁴Rheumatology, Hospital for Special Surgery- Weill Cornell Medicine, New York, NY
Background/Purpose: Lupus anticoagulant hypoprothrombinemia syndrome (LA-HPS) is a rare condition that may predispose to both thrombosis and bleeding due to positive lupus anticoagulant (LA) and…
Abstract Number: 3171 • 2016 ACR/ARHP Annual Meeting
The Impact of Statin Use on Mortality in Systemic Autoimmune Rheumatic Diseases
April Jorge, Na Lu and Hyon K. Choi, Rheumatology, Allergy, and Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA
Background/Purpose: Individuals with systemic autoimmune rheumatic diseases (SARDs)—such as systemic lupus erythematosus (SLE) and systemic sclerosis (SSc)—have been found to have an increased risk of…
Abstract Number: 1079 • 2016 ACR/ARHP Annual Meeting
Discovery of Novel Autoantigens in Sjogren’s Syndrome with Potential for Subgrouping of Disease
Peter Schulz-Knappe¹, Petra Budde¹, Hans-Dieter Zucht¹, Heike Göhler¹, Klaus Marquart¹, Prof. Dr. Matthias Schneider² and Torsten Witte³, ¹Protagen AG, Dortmund, Germany, ²Department of Rheumatology, Univ. Duesseldorf, Duesseldorf, Germany, ³Department of Clinical Immunology and Rheumatology, Hannover Medical School, Hannover, Germany
Background/Purpose: Primary Sjögren’s syndrome (pSS) is a common autoimmune disease with exocrine gland dysfunction and multi-organ involvement. With the growing interest in conducting clinical trials…
Abstract Number: 1764 • 2016 ACR/ARHP Annual Meeting
Effect of Disease Remission on Organ Damage and Quality of Life in Chinese Patients with Systemic Lupus Erythematosus
Chi Chiu Mok¹, Ling Yin Ho², Sau Mei Tse¹ and Kar Li Chan¹, ¹Medicine, Tuen Mun Hospital, Hong Kong, Hong Kong, ²Dept of Medicine, Tuen Mun Hospital, Hong Kong SAR, Hong Kong
Background/Purpose: To study the effect of disease remission on quality of life and organ damage in patients with systemic lupus erythematosus. Methods: Consecutive patients who fulfilled the…
Abstract Number: 2784 • 2016 ACR/ARHP Annual Meeting
Mesenchymal Stem Cells Ameliorate Lupus By Promoting T Cell Apoptosis Via Bcl-2/Bim Independent Pathway in MRL/Lpr Mice
Saisai Huang¹, Dandan Wang² and Lingyun Sun¹, ¹Department of Rheumatology and Immunology, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, China, ²Department of Rheumatology and immunology, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, China
Background/Purpose: Systemic lupus erythematosus (SLE) is an inflammatory autoimmune disease, involving in dysfunction of many organs. The abnormality of apoptosis plays an important role in…
Abstract Number: 3195 • 2016 ACR/ARHP Annual Meeting
Patterns and Predictors of Hydroxychloroquine Nonadherence in a Nationwide Cohort of Medicaid Beneficiaries with Systemic Lupus Erythematosus
Candace H. Feldman¹, Jamie E. Collins², Zhi Zhang³, Daniel H. Solomon⁴, Karen H. Costenbader¹ and Ichiro Kawachi⁵, ¹Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, ²Orthopaedic and Arthritis Center for Outcomes Research, Department of Orthopedic Surgery, Brigham & Women's Hospital, Boston, MA, ³Division of Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, ⁴Brigham and Women’s Hospital and Harvard Medical School, Boston, MA, ⁵Social and Behavioral Sciences, Harvard T. H. Chan School of Public Health, Boston, MA
Background/Purpose: Hydroxychloroquine (HCQ) is the standard of care medication for most SLE patients, however cross-sectional studies suggest that nonadherence is common. Similar to the fluctuating…
Abstract Number: 1087 • 2016 ACR/ARHP Annual Meeting
Nonmemory B Cell Signature Alterations in Belimumab Patients
Karina Marianne D. Torralba¹, Vaneet Sandhu², Abigail Benitez¹ and Sheila Lezcano³, ¹Rheumatology, Loma Linda University, Loma Linda, CA, ²Division of Rheumatology, Loma Linda University, Loma Linda, CA, ³Rheumatology, Loma Linda University Medical Center, Loma Linda, CA
Background/Purpose: Insight into B cell subset dynamics and homeostasis can provide a biological rationale for use of B cell targeted therapies in SLE patients. Using…
Abstract Number: 1778 • 2016 ACR/ARHP Annual Meeting
Differences Between Early and Late Cardiovascular Disease in a Population-Based Cohort of Systemic Lupus Erythematosus Patients
Shivani Garg¹, Gaobin Bao², Mugisha Niyibizi³, Cristina Drenkard⁴ and S. Sam Lim², ¹Rheumatology, Emory University, Atlanta, GA, ²Medicine, Emory University School of Medicine, Atlanta, GA, ³Emory University, atlanta, GA, ⁴Emory University School of Medicine, Atlanta, GA
Background/Purpose: It has long been known that mortality after years of systemic lupus erythematosus (SLE) is often associated with cardiovascular disease (CVD). Recent studies have…
Abstract Number: 2790 • 2016 ACR/ARHP Annual Meeting
Selective Disruption of Estrogen Receptor Alpha Expression in Dendritic Cells of Lupus-Prone Mice Results in Increased Female-Specific Death
Melissa A. Cunningham¹, Jena R. Wirth², Jackie G. Eudaly² and Gary S. Gilkeson³, ¹Rheumatology and Immunology, Medical University of South Carolina, Charleston, SC, ²Med/Rheumatology, Medical University of South Carolina, Charleston, SC, ³Department of Medicine, Medical University of South Carolina, Charleston, SC
Background/Purpose: SLE is a disease that disproportionately affects females. The etiology of the sex bias in this disease is unclear. We previously showed that a…
Abstract Number: 3238 • 2016 ACR/ARHP Annual Meeting
Depression Symptoms throughout the Lifespan in a Low-Income, Minority Cohort of Lupus Patients: Who Is at Risk?
Tamar Rubinstein¹, Noa Schwartz², Nicole Jordan³, Rebecca Lois⁴, Dawn Wahezi^5,6, Ruth E K Stein^7,8 and Chaim Putterman², ¹Division of Pediatric Rheumatology, Albert Einstein College of Medicine, Children's Hospital at Montefiore, Bronx, NY, ²Division of Rheumatology, Albert Einstein College of Medicine, Bronx, NY, ³Montefiore Medical Center, New York, NY, ⁴Psychiatry and Pediatrics, Albert Einstein College of Medicine, Children's Hospital at Montefiore, Bronx, NY, ⁵Pediatric Rheumatology, Albert Einstein College of Medicine, Bronx, NY, ⁶Pediatric Rheumatology, The Children's Hospital at Montefiore, Bronx, NY, ⁷Pediatrics, Children's Hospital at Montefiore, Bronx, NY, ⁸Pediatrics, Albert Einstein College of Medicine, Bronx, NY
Background/Purpose: Depression is commonly seen in lupus, but widely varying prevalence rates have been reported. This may be due to different demographics and characteristics…
Abstract Number: 1151 • 2016 ACR/ARHP Annual Meeting
A Pediatric Rheumatology Fellow Educating Pediatric Primary Care and Emergency Room Providers about Pediatric Lupus: A Local, Pilot Adaptation of the Lupus Education Advancement Project (LEAP)
Katherine Steigerwald¹, Amy Caron², Diane Gross³, Zoon Naqvi⁴ and Yonit Sterba⁵, ¹Pediatrics, The Children's Hospital at Montefiore, Bronx, NY, ²Lupus Research Institute, New York City, NY, ³S.L.E. Lupus Foundation/Lupus Research Institute, New York, NY, ⁴Albert Einstein College of Medicine, Bronx, NY, ⁵Pediatric Rheumatology, The Children's Hospital at Montefiore, Bronx, NY
Background/Purpose: Pediatric systemic lupus erythematosus (SLE) accounts for approximately 10-20% of all cases of SLE. It is more common in African American and Hispanic patients,…
Abstract Number: 1789 • 2016 ACR/ARHP Annual Meeting
Herpetic Viruses in Lupus
Teja Kapoor¹, Pooja Mahadeshwar², Barkha Bhandari³, Jianhua Li⁴, Joan Bathon⁵, Samantha Nguyen⁶ and Anca D. Askanase⁷, ¹Medicine, Division of Rheumatology, Columbia University Medical Center, New York, NY, ²George Washington University Hospital, Washington, DC, ³American University of Antigua, Antigua Guatemala, Antigua and Barbuda, ⁴Department of Biomedical Informatics, Columbia University Medical Center, New York, NY, ⁵Rheumatology, Columbia University, College of Physicians & Surgeons, New York, NY, ⁶Columbia University Medical Center, NY, NY, ⁷Medicine, Rheumatology, Columbia University Medical Center, New York, NY
Background/Purpose: This is a retrospective cohort study evaluating the prevalence of VZV and HSV in SLE patients hospitalized at Columbia University Medical Center-New York…
Abstract Number: 2802 • 2016 ACR/ARHP Annual Meeting
Comparison of the Clinical, Serological, and Prognostic Differences Among Juvenile-, Adult-, and Late-Onset Lupus Nephritis in Korean Patients: A Case-Control Study
Jeong-Won Lee¹, Ji-Hyoun Kang², Dong-Jin Park², Yi-Rang Yim¹, Ji-Eun Kim¹, Kyung-Eun Lee², Lihui Wen¹, Tae-Jong Kim³, Yong-Wook Park² and Shin-Seok Lee³, ¹Chonnam National University Medical School and Hospital, Gwangju, South Korea, ²Rheumatology, Chonnam National University Medical School and Hospital, Gwangju, South Korea, ³Rheumatology, Chonnam National University Medical School and Hospital, Gwangju, Korea, The Republic of
Background/Purpose: SLE patients present with different clinical and serological manifestations according to the age at disease onset. However, it is not known whether there is…
Abstract Number: 3240 • 2016 ACR/ARHP Annual Meeting
Interferon Kappa Is a Novel Type I IFN That Drives Cutaneous Inflammation in Systemic Lupus
Jasmine Stannard¹, Tamra J. Reed², Emily Myers³, Lori Lowe⁴, Mrinal Sarkar⁴, Xianying Xing⁵, Celine C. Berthier⁶, Johann Gudjonsson⁴ and J. Michelle Kahlenberg⁷, ¹Int. Medicine/Rheumatology, University of Michigan, Ann Arbor, MI, ²Internal Medicine, Rheumatology, University of Michigan, Ann Arbor, MI, ³Internal Medicine, Rheumatology, Georgetown University, Washington, DC, ⁴Dermatology, University of Michigan, Ann Arbor, MI, ⁵Dermatology, University of Michigan, University of Michigan, Ann Arbor, MI, ⁶Nephrology, Division of Nephrology, University of Michigan Medical Center, Ann Arbor, MI, ⁷Internal Medicine, Division of Rheumatology, Division of Rheumatology, University of Michigan Medical Center, Ann Arbor, MI
Background/Purpose: Cutaneous lupus erythematosus (CLE) lesions are disfiguring, scarring, difficult to treat, and affect up to 70% of patients with systemic lupus erythematosus (SLE). Type…
Abstract Number: 1168 • 2016 ACR/ARHP Annual Meeting
The Epidemiology of Individuals Not Fully Meeting Classification Criteria for Systemic Lupus Erythematosus (SLE): The Georgia Lupus Registry
Puja Saxena¹, Gaobin Bao², Cristina Drenkard³ and S. Sam Lim², ¹Rheumatology, Emory University School of Medicine, Atlanta, GA, ²Medicine, Emory University School of Medicine, Atlanta, GA, ³Emory University School of Medicine, Atlanta, GA
Background/Purpose: Identifying individuals as early as possible in the development of an autoimmune disease may lead to important opportunities. This study utilizes an established population-based…

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