Session Type: ACR Poster Session C
Session Time: 9:00AM-11:00AM
Background/Purpose: Autoantibodies in SLE that bind to double-stranded DNA or RNA-binding proteins are strongly associated with high levels of type I interferon (IFN), likely via their ability these antibodies to form nucleic-acid containing immune complexes that can stimulate Toll-like receptors. In this study, we examine whether anti-phospholipid antibodies, which should not have this capacity, are associated with greater type I interferon in SLE patients.
To cite this abstract in AMA style:Iwamoto T, Jolly M, Niewold TB. Associations Between Type I Interferon and Antiphospholipid Antibody Status Differ Between Ancestral Backgrounds [abstract]. Arthritis Rheumatol. 2016; 68 (suppl 10). https://acrabstracts.org/abstract/associations-between-type-i-interferon-and-antiphospholipid-antibody-status-differ-between-ancestral-backgrounds/. Accessed November 25, 2020.
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ACR Meeting Abstracts - https://acrabstracts.org/abstract/associations-between-type-i-interferon-and-antiphospholipid-antibody-status-differ-between-ancestral-backgrounds/