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Abstracts tagged "longitudinal studies"

  • Abstract Number: 1271 • ACR Convergence 2024

    Linkage of the Childhood Arthritis and Rheumatology Research Alliance Registry with the Pediatric Health Information System: Creation of a Comprehensive Childhood-Onset Lupus Dataset

    Jordan Roberts1, Anna Faino2, Min-Lee Chang3, Jonathan Cogen4, Matt Hall5 and Esi Morgan1, and for the CARRA Registry Investigators, 1Seattle Children's Hospital, Seattle, WA, 2Seattle Children's Research Institute, Core for Biostatistics, Epidemiology and Analytics in Research, Seattle, 3Computational Health Informatics Program, Boston Children’s Hospital, Boston, MA, 4Seattle Children’s Hospital, Seattle, WA, 5Children’s Hospital Association, Lenexa, KS

    Background/Purpose: Currently, no comprehensive national multipayer dataset with inpatient and outpatient data exists for childhood rheumatologic diseases, limiting the ability to study outcomes longitudinally and…
  • Abstract Number: 2275 • ACR Convergence 2024

    Cardiovascular and Cancer Safety of JAKi Compared to TNFi in Patients with Rheumatoid Arthritis: Results from a National Registry of Advanced Therapies

    Lucia Otero-Varela1, Carlos Sanchez-Piedra2, Elena Rabadán Rubio3, Juan Camilo Sarmiento-Monroy4, Chamaida Plasencia-Rodríguez5, Diana Sueiro6, Olga Martinez7, Noemí Busquets Pérez8, Mercedes Freire González9, Fernando Sánchez-Alonso10, José María Álvaro-Gracia11 and Isabel Castrejon12, and BIOBADASER group, 1Spanish Society of Rheumatology, Madrid, Spain, 2Agencia de Evaluación de Tecnologías Sanitarias, Instituto de Salud Carlos III, Madrid, Spain, 3Hospital Universitario Principe de Asturias, Alcalá de Henares, Madrid, Spain, 4Hospital Clínic Barcelona, Barcelona, Spain, 5Hospital Universitario La Paz, MADRID, Spain, 6Complexo Hospitalario Universitario de Ourense, Ourense, Spain, 7Hospital Universitario de Salamanca, Zamora, Spain, 8HOSP. GENERAL DE GRANOLLERS, GRANOLLERS, Spain, 9Complexo Hospitalario Universitario de A Coruña, La coruna, Galicia, Spain, 10Sociedad Española de Reumatología, Madrid, Spain, 11Hospital Gregorio Marañón, Madrid, Spain, 12Hospital General Universitario Gregorio Marañon, Madrid, Spain

    Background/Purpose: Preliminary results from the ORAL Surveillance clinical trial showed an increase in the risk of major adverse cardiovascular events (MACE) and malignancies in patients…
  • Abstract Number: 1312 • ACR Convergence 2024

    Long Term Proficiency and Clinical Outcomes of a Novel Fellow’s Injection Clinic

    Rubia Ahmed1, Whitney Martin2, Sharon Banks3, Nancy Olsen4, Vincent Aluquin1 and shirley albano-aluquin1, 1Penn State Hershey College of Medicine, Hershey, PA, 2Lexington Rheumatology, West Columbia, SC, 3Penn State Health, Hershey, PA, 4Penn State University/Milton S Hershey, Hershey, PA

    Background/Purpose: Rheumatology fellows are required to learn joint and periarticular procedures during their training but achieving the necessary expertise can be challenging if the rotations…
  • Abstract Number: 2379 • ACR Convergence 2024

    Causal Proteomics-Assisted Machine Learning Model Enhances Flare Risk Prediction in Systemic Lupus Erythematosus

    Liying Chen1, Ou Deng2, Ruichen Cong2, Dingqi Lu3, Ting Fang1, Mei Chen1, Runrun Zhang4 and Xinchang Wang3, 1Second Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou, China (People's Republic), 2Graduate School of Human Sciences, Waseda University, Mikajima, Japan, 3Department of Rheumatology, The Second Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China (People's Republic), 4The Second Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China (People's Republic)

    Background/Purpose: Objectives: Systemic lupus erythematosus (SLE) is an autoimmune disease marked by unpredictable flares. However, no flare risk prediction model has been developed for Asian…
  • Abstract Number: 1326 • ACR Convergence 2024

    Which Biomarkers Indicate Imminent Progression to Inflammatory Arthritis in High Risk CCP Positive Persons?

    Laurence Duquenne1, Didem Sahin Eroglu2, Jianhua Wu3, Kate Harnden1, Andrea Di Matteo4, Lucy Elizabeth Thornton5, Rahaymin Chowdhury5, Leticia Garcia-Montoya1, Kulveer Mankia6 and Paul Emery6, 11. Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, 2. NIHR Leeds Biomedical Research Centre, United Kingdom, Leeds, United Kingdom, 21. Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, 2. NIHR Leeds Biomedical Research Centre, United Kingdom, Ankara, Turkey, 31. University of Leeds, Leeds Institute for Data Analytics, Leeds, United Kingdom 2.Wolfson Institute of Population Health/Queen Mary University of London, UK, Leeds, 41. Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, 2. NIHR Leeds Biomedical Research Centre, United Kingdom, Jesi, Italy, 51. Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, 2. NIHR Leeds Biomedical Research Centre, United Kingdom, Leeds, 6University of Leeds, Leeds, United Kingdom

    Background/Purpose: A risk stratification model proposed a simple score using 4 biomarkers to identify those at high risk of developing inflammatory arthritis (IA) in primary…
  • Abstract Number: 2390 • ACR Convergence 2024

    Anti-Sm Antibody Titers Vary During SLE Disease Course

    Faye Megaris1, Emily Wu2 and Kyriakos Kirou3, 1CUNY School of Medicine, Astoria, NY, 2Hospital for Special Surgery, Rochester, NY, 3Hospital for Special Surgery, New York, NY

    Background/Purpose: Systemic Lupus Erythematosus (SLE) is characterized by positive antibodies to dsDNA and/or Sm which have high specificity for the disease. While anti-dsDNA titers are…
  • Abstract Number: 1368 • ACR Convergence 2024

    Do CsDMARDs Still Play a Significant Role in Managing Rheumatoid Arthritis in the Current Biologic/JAKI Era? A Prospective Observational Study to Estimate the Extent of Response to Conventional Synthetic DMARDs in RA– Experience from a Tertiary Care Center in South India

    Prabhu Vasanth1, John Mathew2 and Divya K3, 1Christian Medical college , Vellore , India, Vellore, Tamil Nadu, India, 2Christian Medical college , Vellore , India, Vellore, India, 3Christian Medical College, Vellore, Tamil Nadu, India

    Background/Purpose: Conventional synthetic DMARDs remained the mainstay of treatment of RA for decades. However, their use has decreased recently due to the emergence of biological…
  • Abstract Number: 2455 • ACR Convergence 2024

    Improvement Across Multi-organ Domains and Patient Reported Outcomes in Refractory Juvenile-Onset Systemic Sclerosis (jSSc) up to 4 Years After Autologous Stem Cell Transplantation (ASCT)

    Jonathan Li1, Paulina Horvei2, Franziksa Rosser3, Kirsten Rose-Felker4, Vibha Sood5, Adam Olson6, Vickie Vandergrift7, Nicole Hogue2, Lauren Farver8, Devin Mcguire9, Haley Havrilla7, Jessie Alexander10, Shawna McIntyre2, Paul Szabolcs2 and Kathryn Torok11, 1Division of Rheumatology, Department of Pediatrics, UPMC Children’s Hospital of Pittsburgh, Pittsburgh, PA, USA, Pittsburgh, PA, 2Division of Blood and Marrow Transplantation and Cellular Therapies, Department of Pediatrics, UPMC Children’s Hospital of Pittsburgh, Pittsburgh, PA, USA, Pittsburgh, 3Division of Pulmonology Medicine, Department of Pediatrics, UPMC Children’s Hospital of Pittsburgh, Pittsburgh, PA, USA, Pittsburgh, PA, 4Division of Cardiology, Department of Pediatrics, UPMC Children’s Hospital of Pittsburgh, Pittsburgh, PA, USA, Pittsburgh, 5Division of Pediatric Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, UPMC Children’s Hospital of Pittsburgh, Pittsburgh, PA, USA, Pittsburgh, 6Department of Radiation Oncology, UPMC Children’s Hospital of Pittsburgh, Pittsburgh, PA, USA, Pittsburgh, 7Division of Rheumatology, Scleroderma Center, Department of Pediatrics, UPMC Children’s Hospital of Pittsburgh, Pittsburgh, PA, USA, Pittsburgh, 8Department of Physical Therapy, UPMC Children’s Hospital of Pittsburgh, Pittsburgh, PA, USA, Pittsburgh, 9Pediatric Behavioral Health, University of Pittsburgh, Pittsburgh, PA, USA, Pittsburgh, 10Pediatric Bone Marrow Transplant and Cellular Therapies, Stanford Children's Hospital, Palo Alto, CA, USA, Pittsburgh, 11Division of Rheumatology, Scleroderma Center, Department of Pediatrics, UPMC Children’s Hospital of Pittsburgh, Pittsburgh, PA, USA, Pittsburgh, PA

    Background/Purpose: Juvenile-onset systemic sclerosis (jSSc) is a systemic autoimmune disease characterized by vasculopathy and multiorgan fibrosis leading to significant morbidity and early mortality.  Autologous stem…
  • Abstract Number: 1229 • ACR Convergence 2023

    Longitudinal Assessment of Self-reported Executive Function in Youth with Childhood-Onset Lupus

    Tala El Tal1, justine ledochowski2, Sarah Mossad3, Victoria Lishak3, Ibrahim Mohamed4, Joanna Law3, Lawrence Ng3, Paris Moaf3, Asha Jeyanathan3, Adrienne Davis3, Linda Hiraki3, Deborah Levy3, Zahi Touma5, Natoshia Cunningham6, Ashley Danguecan3 and Andrea Knight3, 1Division of Rheumatology, The Hospital for Sick Children, andDivision of Rheumatology, Children’s Hospital of Eastern Ontario, Ottawa, ON, Canada, 2Department of Psychology, The Hospital for Sick Children, Toronto, ON, Canada, 3The Hospital for Sick Children, Toronto, ON, Canada, 4The Hospital for Sick Children, Brampton, ON, Canada, 5University of Toronto, Toronto, ON, Canada, 6Michigan State University, Grand Rapids, MI

    Background/Purpose: Cognitive dysfunction (including executive dysfunction) affects up to 60% of youth with childhood-onset systemic lupus erythematosus (cSLE), with potential adverse effects on health-related quality…
  • Abstract Number: 2452 • ACR Convergence 2023

    Assessment of Association Between Hydroxychloroquine Use and Toxic Retinopathy, Overall and by Indication, in a Large Cohort of Rheumatology Patients Within the US Department of Defense Military Healthcare System

    Rachel Robbins1, Toni Rush2 and Jess Edison3, 1Walter Reed National Military Medical Center, Germantown, MD, 2Health Research Tx, Pace, FL, 3Uniformed Services University of the Health Sciences / National Capital Consortium- Walter Reed Bethesda, Bethesda, MD

    Background/Purpose: While generally believed to be a safe, well-established treatment, hydroxychloroquine (HCQ) use is associated with irreversible retinal toxicity requiring regular monitoring. The objective of…
  • Abstract Number: 1243 • ACR Convergence 2023

    Tubulointerstitial Inflammation Is Associated with End-Stage Renal Disease in Pediatric Lupus Nephritis: A Single Center Retrospective Cohort Study

    Ryan Mitacek, Qiong Liu, Linda Wagner-Weiner, Shireen Hashmat and Anthony Chang, University of Chicago, Chicago, IL

    Background/Purpose: Lupus nephritis (LN) is associated with significant morbidity and mortality. The 2018 International Society of Nephrology/Renal Pathology Society (ISN/RPS) classification criteria and the NIH…
  • Abstract Number: 2510 • ACR Convergence 2023

    Autoantibody-positivity Before Treatment Is Associated with Immune-related Adverse Events in Melanoma Patients Treated with anti-PD-1

    Tineke van Wesemael1, Jessica Borgers2, Kyra Gelderman3, Els Verdegaal4, C.M. Korse5, M.J.P. Welters6, Ellen Kapiteijn7, W.J. van Houdt2, Sjoerd van der Burg6, René Toes1, J.V. Thienen2, John Haanen2 and Diane van der Woude1, 1Leiden University Medical Center, Leiden, Netherlands, 2Department of Medical Oncology, Netherlands Cancer Institute, Amsterdam, Netherlands, 3Sanquin Diagnostic Services, Amsterdam, Netherlands, 4Department of Medical Oncology, Oncode Institute, Leiden University Medical Center, Amsterdam, Netherlands, 5Department of Laboratory Medicine, Antoni Van Leeuwenhoek, The Netherlands Cancer Institute, Amsterdam, Netherlands, 6Department of Medical Oncology, Oncode Institute, Leiden University Medical Center, Leiden, Netherlands, 7Department of Medical Oncology, Leiden University Medical Center, Leiden, Netherlands

    Background/Purpose: PD-1 immune checkpoint inhibitors are able to re-activate restrained anti-tumor T-cell responses in melanoma patients. However, PD-1 inhibition may also activate auto-reactive T-cells leading…
  • Abstract Number: 1295 • ACR Convergence 2023

    Having More Tender Than Swollen Joints Is Associated with Worse Functional Outcomes in Patients with Early RA in a Prospective Real-World Cohort

    Charis Meng1, Yvonne Lee2, Orit Schieir3, Marie-France Valois4, Margaret Butler1, Gilles Boire5, Glen Hazelwood6, Carol Hitchon7, Edward Keystone8, Diane Tin9, Carter Thorne10, Louis Bessette11, Janet Pope12, Susan Bartlett13 and Vivian Bykerk1, 1Hospital for Special Surgery, New York, NY, 2Northwestern University, Chicago, IL, 3McGill University, Montréal, QC, Canada, 4McGill University, Pointe-Claire, QC, Canada, 5Université de Sherbrooke, Sherbrooke, QC, Canada, 6University of Calgary, Calgary, AB, Canada, 7University of Manitoba, Manitoba, MB, Canada, 8Keystone Consulting Enterprises Inc., Toronto, ON, Canada, 9Centre of Arthritis Excellence, Newmarket, ON, Canada, 10Southlake Regional Health Centre, Newmarket, ON, Canada, 11Centre de l'Ostéoporose et de Rhumatologie de Québec, Quebec City, QC, Canada, 12University of Western Ontario, London, ON, Canada, 13McGill University, Montreal, QC, Canada

    Background/Purpose: Early RA patients may present with more tender than swollen joints, which can persist during DMARD therapy. Elevated TSJD (tender-swollen joint difference) is often…
  • Abstract Number: 2517 • ACR Convergence 2023

    The Relationship Between the NETosis Findings and Disease Activity in Behcet Disease

    Erdem Bektas1, Rabia Deniz2, Zeliha Emrence3, Sema Sırma Ekmekci3, Neslihan Abacı3, Shirkhan Amikishiyev4, Yasemin Yalçınkaya4, Bahar Artim Esen4, Murat Inanç5 and Ahmet Gul6, 1Istanbul University, Istanbul Faculty of Medicine, Department of Internal Medicine, Istanbul, Turkey, 2University of Health Sciences, Basaksehir Cam and Sakura City Hospital, Department of Rheumatology, Istanbul, Turkey, 3Istanbul University, Aziz Sancar Institute of Experimental Medicine, Department of Genetics, Istanbul, Turkey, 4Istanbul University, Istanbul Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology, Istanbul, Turkey, 5Istanbul University, Istanbul, Turkey, 6Division of Rheumatology, Department of Internal Medicine, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey

    Background/Purpose: Behcet disease (BD) is a multisystemic inflammatory disease of unknown etiology. BD has been classified among the neutrophilic dermatosis, and neutrophil extracellular traps (NETs)…
  • Abstract Number: 1303 • ACR Convergence 2023

    Patient’s and Physician’s Evaluation of Global Assessment of Disease Activity over Follow up and Across Disease Activity Levels in Recent-Onset Rheumatoid Arthritis

    Audrey-Anne Couture1, Nathalie Carrier2, Hugues Allard-Chamard3, Sophie ROUX3, Patrick Liang3 and Gilles Boire3, 1University of Montréal, Montréal, QC, Canada, 2CIUSSS de l'Estrie - CHUS, Sherbrooke, QC, Canada, 3Université de Sherbrooke, Sherbrooke, QC, Canada

    Background/Purpose: Composite measures (e.g. SDAI) to assess Rheumatoid Arthritis (RA) disease activity incorporate patient (PGA) and evaluator (EGA) global assessments. EGA and PGA are often…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM CT on October 25. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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