Abstracts tagged "Knee"

Abstract Number: 2185 • 2017 ACR/ARHP Annual Meeting
Relation of Foot Pronation to Medial Knee Load in Persons with Medial Knee Osteoarthritis
K. Douglas Gross¹, Richard Jones², David T. Felson³, Salinda Chong⁴ and Howard J. Hillstrom⁵, ¹Physical Therapy, MGH Institute of Health Professions, Boston, MA, ²School of Health Sciences, University of Salford, Manchester, United Kingdom, ³Arthritis Research UK Centre for Epidemiology, Institute of Inflammation and Repair, University of Manchester, Manchester, United Kingdom, ⁴MGH Institute of Health Professions, Boston, MA, ⁵Rehabilitation, Hospital Special Surgery (HSS), New York, NY
Background/Purpose: The knee adduction moment (KAM) estimates medial knee load during gait, with high KAM fueling worsening OA. Understanding how foot mechanics contribute to KAM…
Abstract Number: 1192 • 2017 ACR/ARHP Annual Meeting
Patient Characteristics That Predict the Effect of Laparoscopic Adjustable Gastric Band Weight Loss Surgery on Knee Osteoarthritis Pain
Shannon Chen¹, Fernando Bomfim², Heekoung Youn³, Christine Ren-Fielding⁴ and Jonathan Samuels⁵, ¹Medicine, NYU Langone Medical Center, New York, NY, ²NYU Langone Medical Center, New York, NY, ³Surgery, NYU Langone Medical Center, New York, NY, ⁴Department of Surgery, New York University School of Medicine, New York, NY, ⁵Department of Medicine, NYU School of Medicine, NYU Langone Medical Center, New York, NY
Background/Purpose: Obesity is a modifiable risk factor for knee osteoarthritis (OA), yet diet and exercise often fail to achieve sustained weight loss or knee improvement.…
Abstract Number: 2189 • 2017 ACR/ARHP Annual Meeting
Metabolic Syndrome Influences the Radiographic Progression of Knee Osteoarthritis and Condition the Risk of Erosive Hand OA
Natividad Oreiro¹, Mercedes Fernandez Moreno², Estefanía Cortés-Pereira², Maria Eugenia Vazquez Mosquera³, Sonia Pertega⁴, Sara Relaño-Fernandez⁵, Ana Cecilia Raga⁶, Carlos Fernandez-Lopez⁶, Ignacio Rego-Pérez⁶ and Francisco J Blanco⁶, ¹Servicio de Reumatología. Instituto de Investigación Biomédica de A Coruña (INIBIC), Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas. Universidade da Coruña (UDC). As Xubias, 15006. A Coruña. España, A Coruna, Spain, ²Servicio de Reumatología. Instituto de Investigación Biomédica de A Coruña (INIBIC). Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas. Universidade da Coruña (UDC). As Xubias, 15006. A Coruña, España, A Coruna, Spain, ³Servicio de Reumatología. Instituto de Investigación Biomédica de A Coruña (INIBIC). Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas. Universidade da Coruña (UDC). As Xubias, 15006. A Coruña, España, A Coruña, Spain, ⁴Unidad de Epidemiología Clínica y Bioestadística. Instituto de Investigación Biomédica de A Coruña (INIBIC). Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas. Universidade da Coruña (UDC). As Xubias, 15006. A Coruña, España, A Coruña, Spain, ⁵Plataforma de Genómica. Instituto de Investigación Biomédica de A Coruña (INIBIC). Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas. Universidade da Coruña (UDC). As Xubias, 15006. A Coruña, España, A Coruña, Spain, ⁶Servicio de Reumatología. Instituto de Investigación Biomédica de A Coruña (INIBIC), Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas. Universidade da Coruña (UDC). As Xubias, 15006. A Coruña. España, A Coruña, Spain
Background/Purpose: The contribution of metabolic factors in the development of OA has not been fully elucidated. The aim of this work is to analyze the…
Abstract Number: 1194 • 2017 ACR/ARHP Annual Meeting
Are Bisphosphonates Efficacious in Knee Osteoarthritis? A Meta-Analysis of Randomized Controlled Trials
Mikala C. Osani¹, Elizaveta Vaysbrot¹, Raveendhara R. Bannuru², Mia-Cara Musetti¹ and Timothy E. McAlindon¹, ¹Division of Rheumatology, Tufts Medical Center, Boston, MA, ²Center of Integrative Medicine and Division of Rheumatology, Tufts Medical Center, Boston, MA, Boston, MA
Background/Purpose: One of the key aspects of osteoarthritis (OA) pathogenesis is subchondral bone remodeling. Bisphosphonates have been touted as disease-modifying agents for OA due to…
Abstract Number: 2192 • 2017 ACR/ARHP Annual Meeting
Association between Mitochondrial DNA (mtDNA) Haplogroups and Bone Marrow Lesions at 24 Months in Osteoarthritis Subjects: Subjets from the Osteoarthritis Initiative
Ignacio Rego-Pérez¹, Jean-Pierre Pelletier², François Abram³, Natividad Oreiro⁴, Carlos Fernandez-Lopez¹, Ana Cecilia Raga¹, Francisco J Blanco¹ and Johanne Martel-Pelletier², ¹Servicio de Reumatología. Instituto de Investigación Biomédica de A Coruña (INIBIC), Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas. Universidade da Coruña (UDC). As Xubias, 15006. A Coruña. España, A Coruña, Spain, ²Osteoarthritis Research Unit, University of Montreal Hospital Research Centre (CRCHUM), Montreal, QC, Canada, ³Medical Imaging Research & Development, ArthroLab Inc., Montreal, QC, Canada, ⁴Servicio de Reumatología. Instituto de Investigación Biomédica de A Coruña (INIBIC), Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas. Universidade da Coruña (UDC). As Xubias, 15006. A Coruña. España, A Coruna, Spain
Background/Purpose: Bone marrow lesions (BMLs) have been consistently associated with the development of osteoarthritis (OA); however the extent to which they are genetically driven by…
Abstract Number: 1198 • 2017 ACR/ARHP Annual Meeting
Intra-Articular Hyaluronic Acid Delay to Total Knee Arthroplasty By Number of Injection Courses Received: Analysis of an Administrative Database
Andrew Concoff¹, Faizan Niazi², Peter Shaw² and Jeffrey Rosen³, ¹Rheumatology, St. Jude Medical Center, Fullerton, CA, ²Ferring Pharmaceuticals Inc., Parsippany, NJ, ³Department of Orthopaedics & Rehabilitation, New York Presbyterian Queens; Department of Clinical Orthopaedic Surgery, Weill Medical College of Cornell University, New York, NY, New York, NY
Background/Purpose: Total knee arthroplasty (TKA) is the standard surgical treatment for patients with osteoarthritis (OA) that no longer experience symptom relief from conservative or pharmacologic…
Abstract Number: 2193 • 2017 ACR/ARHP Annual Meeting
Physical Activity and Disease Progression in Persons with or at Higher Risk for Knee Osteoarthritis
Prakash Jayabalan^1,2, Gerald W. Rouleau¹, Masha Kocherginsky¹, Dorothy D. Dunlop¹, Julia (Jungwha) Lee¹, Rowland W. Chang¹ and Leena Sharma¹, ¹Northwestern University, Chicago, IL, ²Shirley Ryan AbilityLab, Chicago, IL
Background/Purpose: The benefits of physical activity in the general population and among persons with knee osteoarthritis (OA) are well-established. However, it remains unclear if inactivity…
Abstract Number: 312 • 2017 ACR/ARHP Annual Meeting
Rates of Total Joint Replacement Utilization in the U.S.: Future Projections to 2020-2040 Using the National Inpatient Sample
Jasvinder A. Singh and Shaohua Yu, University of Alabama at Birmingham, Birmingham, AL
Background/Purpose: To project the future utilization of total hip and knee joint arthroplasty (THA, TKA).Methods: We used the 2000-2010 U.S. National Inpatient Sample combined with…
Abstract Number: 1199 • 2017 ACR/ARHP Annual Meeting
Costs Associated with Osteoarthritis Care Using Intra-Articular Hyaluronic Acid: Analysis of an Administrative Database
Andrew Concoff¹, Faizan Niazi², Peter Shaw² and Jeffrey Rosen³, ¹Rheumatology, St. Jude Medical Center, Fullerton, CA, ²Ferring Pharmaceuticals Inc., Parsippany, NJ, ³Department of Orthopaedics & Rehabilitation, New York Presbyterian Queens; Department of Clinical Orthopaedic Surgery, Weill Medical College of Cornell University, New York, NY, New York, NY
Background/Purpose: Many treatment options are available for the management of knee osteoarthritis (OA). The need for non-operative management is motivated by the large costs associated…
Abstract Number: 2197 • 2017 ACR/ARHP Annual Meeting
Systemic Inflammation and Physical Function in Knee Osteoarthritis
Devyani Misra¹, Carrie Brown², Roger A. Fielding³, Tuhina Neogi⁴, Michael C. Nevitt⁵, Cora E. Lewis⁶, James Torner⁷ and David T. Felson⁴, ¹Medicine, Section of, Boston University School of Medicine, Boston, MA, ²Boston University School of Public Health, Boston, MA, ³Nutrition, Exercise Physiology and Sarcopenia Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA, ⁴Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MA, ⁵Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, ⁶University of Alabama Birmingham, Birmingham, AL, ⁷University of Iowa, Iowa City, IA
Background/Purpose: Knee osteoarthritis (OA) is a leading cause of functional limitation and disability in older adults. But why some knee OA patients develop functional limitation…
Abstract Number: 316 • 2016 ACR/ARHP Annual Meeting
Postural Stability Is Associated with Lower Pain, Lower Stiffness, and Higher Muscle Power Among Adults with Symptomatic Knee Osteoarthritis
Wei Liu¹, Augustine C. Lee², William F. Harvey², Lori Lyn Price³, Jeffrey B. Driban² and Chenchen Wang², ¹Osteopathic Rehabilitation and Biomechanics, 1Edward Via College of Osteopathic Medicine, Auburn, AL, USA, Auburn, AL, ²Rheumatology, Tufts Medical Center, Boston, MA, ³Clinical Care Research, Tufts Medical Center, Boston, MA
Background/Purpose: Postural stability is an indicator of static standing balance and a critical component of physical function and fall prevention among those with knee OA.…
Abstract Number: 2343 • 2016 ACR/ARHP Annual Meeting
A Phase 2, Multi-Center, Randomized, Double-Blind, Active-Controlled, Parallel Group Study to Evaluate the Safety and Dose Effectiveness of Intradermal Injections of Purified Apis Mellifera Toxin to Improve Pain and Physical Function in Patients with Osteoarthritis of the Knee
Douglas R. Schumacher¹, Anna Jakubowska² and Christopher M.H. Kim³, ¹Radiant Research, Columbus, OH, ²Apimeds, Inc., Jungwongu, Seongnam, Gyeonggido, Korea, The Republic of, ³CHA University, Bundanggu, Seongnam, Gyeongghido, Korea, The Republic of
Background/Purpose: This Phase 2a/b trial evaluated the safety and dose effectiveness of honeybee toxin (purified Apis melliferatoxin) injections to improve pain and physical function in…
Abstract Number: 448 • 2016 ACR/ARHP Annual Meeting
Cross-Cultural and Construct Validity of the Animated Activity Questionnaire to Assess Activity Limitations in Patients with Hip and Knee Osteoarthritis in Different Languages
Wilfred Peter¹, Henrica de Vet², Maarten Boers³, Jaap Harlaar⁴, Leo D. Roorda⁵, Rudolf Poolman⁶, Vanessa Scholtes⁷, Martijn P.M. Steultjens⁸, Gordon Hendry⁹, Ewa M. Roos¹⁰, Francis Guillemin¹¹, Maria Grazia Benedetti¹², Lorenzo Cavazutti¹², Antonio Escobar Martinez¹³, Hanne Dagfinrud¹⁴ and Caroline Terwee¹⁵, ¹Department of Epidemiology and Biostatistics, VU University Medical Centre, Amsterdam, Netherlands, ²EMGO Institute, VU Medical Centre, Amsterdam, Netherlands, ³Epidemiology & Biostatistics, VU Univ Medical Center F-wing, Amsterdam, Netherlands, ⁴Dep of Rehabilitation Medicine and MOVE research institute, VU University Medical Center, Amsterdam, Netherlands, ⁵Amsterdam Rehabilitation Research Center | Reade, Amsterdam, the Netherlands, Amsterdam, Netherlands, ⁶Orthopedic department, Joint Reserach, OLVG, Amsterdam, Netherlands, ⁷Department of Orthopedics, Joint Research, Onze Lieve Vrouwe Gasthuis, Amsterdam, Netherlands, ⁸Rehabilitation Medicine, VU University Medical Center, Amsterdam, Netherlands, ⁹School of Health and Life Sciences, Glasgow Caledonian University, Glasgow, United Kingdom, ¹⁰Inst Sports and Biomechanics, University of Southern Denmark, Odense, Denmark, ¹¹University of Lorraine, Nancy, France, ¹²Physical Medicine and Rehabilitation Unit, Istituto Ortopedico Rizzoli, Bologna, Italy, ¹³Health Service Research Network on Chronic Diseases (REDISSEC), Basurto University Hospital, Bilbao, Spain, ¹⁴Department of Rheumatology /National Advosory Unit for Rehabilitation in Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, ¹⁵Dep of Epidemiology and Biostatistics, EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, Netherlands
Background/Purpose: Application of the AAQ in international studies requires good cross-cultural validity, i.e. minimal Differential Item Functioning (DIF) across countries. The aim of this study…
Abstract Number: 2344 • 2016 ACR/ARHP Annual Meeting
Inflammation and Glucose Homeostasis Are Associated with Specific Structural Features Among Adults without Knee Osteoarthritis
Alina Stout¹, Mary Barbe², Charles B. Eaton³, Mamta Amin⁴, Fatimah Al Eid¹, Lori Lyn Price⁵, Bing Lu⁶, Grace H. Lo⁷, Ming Zhang⁸, Timothy E. McAlindon⁹ and Jeffrey Driban⁸, ¹Rheumatology, Tufts Medical Center, Boston, MA, ²Temple University School of Medicine, Philadelphia, PA, ³Family Medicine and Community Health( Epidemiology), Alpert Medical School of Brown University, Pawtucket, RI, ⁴Department of Anatomy and Cell Biology, Temple University School of Medicine, Philadelphia, PA, ⁵Clinical Care Research, Tufts Medical Center, Boston, MA, ⁶Brigham & Women's Hospital and Harvard Medical School, Boston, MA, ⁷Immunology, Allergy, Rheumatology, Baylor College of Medicine, Houston, TX, ⁸Tufts Medical Center, Boston, MA, ⁹Division of Rheumatology, Tufts Medical Center, Boston, MA
Background/Purpose: Adults with osteoarthritis (OA) have greater glucose concentrations and inflammation. It remains unclear if inflammation and glucose homeostasis are related to specific features of…
Abstract Number: 449 • 2016 ACR/ARHP Annual Meeting
the Animated Activity Questionnaire to Assess Activity Limitations in Patients with Hip and Knee Osteoarthritis: Reliability, Responsiveness, and Interpretation
Wilfred Peter¹, Henrica de Vet², Rudolf Poolman³, Vanessa Scholtes⁴, Dionne Timmermans⁵, Nina Klein Essink⁵ and Caroline Terwee⁶, ¹Amsterdam Rehabilitation Research Centre, Reade, centre for rehabilitation and rheumatology, Amsterdam, Netherlands, ²EMGO Institute, VU Medical Centre, Amsterdam, Netherlands, ³Orthopedic department, Joint Reserach, OLVG, Amsterdam, Netherlands, ⁴Department of Orthopedics, Joint Research, Onze Lieve Vrouwe Gasthuis, Amsterdam, Netherlands, ⁵Orthopedics, Joint Research, OLVG, Amsterdam, Netherlands, ⁶Dep of Epidemiology and Biostatistics, EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, Netherlands
Background/Purpose: A newly developed and (cross-cultural) validated measurement tool, the computerized Animated Activity Questionnaire (AAQ) for assessing activity limitations in hip and knee osteoarthritis (HKOA)…

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