Abstracts tagged "Knee and osteoarthritis"

Abstract Number: 2082 • 2019 ACR/ARP Annual Meeting
Activity in Work and Life: The Association Between Physical Activity and Employment Status with Future Slow Walking in Knee Osteoarthritis
Jason Jakiela¹, Louise Thoma ², Hiral Master ³, Dana Voinier ¹, Meredith Christiansen ¹, Lauren Neely ¹ and Daniel White ³, ¹University of Delaware, Newark, ²University of North Carolina at Chapel Hill, Newark, ³University of Delaware, Newark, DE
Background/Purpose: Knee osteoarthritis (OA) is the leading cause of functional limitation in older adults, e.g., slow walking. Physical activity (PA) is beneficial for those with…
Abstract Number: 453 • 2018 ACR/ARHP Annual Meeting
Profound Changes in the NaV1.8 Nociceptive Innervation of the Murine Knee Joint after Destabilization of the Medial Meniscus
Alia Obeidat¹, Richard J. Miller², Rachel E. Miller³ and Anne-Marie Malfait⁴, ¹Rush University Medical Center, Chicago, IL, ²Pharmacology/Medical Humanities and Bioethics, Northwestern University, Chicago, IL, ³Biochemistry, Rush University Medical Center, Chicago, IL, ⁴Biochemistry & Rheumatology, Rush University Medical Center, Chicago, IL
Background/Purpose: We aimed to compare the nociceptive innervation of healthy and osteoarthritic mouse knees. Methods: Destabilization of the medial meniscus (DMM) or sham surgery was…
Abstract Number: 945 • 2018 ACR/ARHP Annual Meeting
Pain, Functional Limitations and Physical Activity Participation Trajectories in Patients with Symptomatic Knee and Hip Osteoarthritis: A Multi-Trajectory Analysis
Maud Wieczorek¹, Christine Rotonda¹, Francis Guillemin^1,2 and Anne-Christine Rat^1,3, ¹Université de Lorraine, EA4360, APEMAC, Nancy, France, ²Inserm, CIC-1433 Epidémiologie Clinique, Vandoeuvre-lès-Nancy, France, ³Rheumatology Department, CHRU Nancy, Vandoeuvre-lès-Nancy, France
Background/Purpose: The aims of this study were to identify homogeneous subgroups of knee and/or hip osteoarthritis (OA) patients with distinct trajectories of the combination of…
Abstract Number: 979 • 2017 ACR/ARHP Annual Meeting
What Have We Learned from Trajectory Analysis of Clinical Outcomes in Osteoarthritis?
Maud Wieczorek¹, Anne-Christine Rat^1,2,3, Francis Guillemin^1,2 and Christine Rotonda¹, ¹Université de Lorraine, EA4360, APEMAC, Nancy, France, ²Inserm, CIC-1433 Epidémiologie Clinique, Vandoeuvre-lès-Nancy, France, ³Rheumatology Department, CHRU Nancy, Vandoeuvre-lès-Nancy, France
Background/Purpose: The aims of this review were to summarize the literature on the trajectories of clinical outcomes in knee and hip OA, to describe the…
Abstract Number: 1056 • 2017 ACR/ARHP Annual Meeting
Evolution of Health Care Consumption in the Knee and Hip Osteoarthritis Long Term Assessment Cohort, a French Population Based Cohort of Symptomatic Knee and/or Hip OA Patients
Anne-Christine Rat^1,2,3, Jean-Hugues Salmon⁴, Willy Ngueyon Sime⁵, Maud Wieczorek⁶, Alain Saraux⁷, Claudine Gard⁸, Francis Guillemin⁹ and Bruno Fautrel¹⁰, ¹Inserm, CIC-1433 Epidémiologie Clinique, Vandoeuvre-lès-Nancy, France, ²Rheumatology Department, CHRU Nancy, Vandoeuvre-lès-Nancy, France, ³Université de Lorraine, EA4360, APEMAC, Nancy, France, ⁴Rheumatology, Rheumatology Department CHU Teaching Hospital Reims, Reims, France, ⁵CIC 1433 Epidémiologie clinique, Inserm, Nancy, France, ⁶Université de Lorraine EA 4360 APEMAC, Nancy, France, ⁷Rheumatology Department, Rheumatology Department, CHU de la Cavale Blanche, Brest, France, Brest Cedex, France, ⁸Pitié Salpetrière hospital, Paris, France, ⁹CHRU Nancy, Clinical Epidemiology and Evaluation, Université de Lorraine, Paris Descartes University, APEMAC, EA 4360, Nancy, France, ¹⁰UPMC University Paris 06, Pitié-Salpétrière Hospital, Paris, France
- Background/Purpose: in hip and knee OA, one of the leading causes of global disability, recent population-based data of health care practices and utilization are scarce.…
Abstract Number: 1191 • 2017 ACR/ARHP Annual Meeting
Efficacy and Safety of Cntx-4975 in Subjects with Moderate to Severe Osteoarthritis Knee Pain: 24-Week, Randomized, Double-Blind, Placebo-Controlled, Dose-Ranging Study
Randall Stevens¹, Dena Petersen², John Ervin³, Jennifer Nezzer⁴, Yeni Nieves⁴, James Campbell¹, Kimberly Guedes¹, Robin Burges¹ and Peter Hanson¹, ¹Centrexion Therapeutics, Boston, MA, ²Noble Clinical Research, Tucson, AZ, ³Center for Pharmaceutical Research, Kansas City, MO, ⁴Premier Research, Durham, NC
Background/Purpose: CNTX-4975, a highly purified, synthetic trans-capsaicin, targets transient receptor potential vanilloid 1, producing analgesia via reversible desensitization of end terminals of primary afferent pain…
Abstract Number: 2177 • 2017 ACR/ARHP Annual Meeting
The Medial Shift of the Tibial Articular Surface Is One Factor of Medial Osteoarthritis of the Knee
Ryuji Nagamine, Artificial joint and rheumatism, Fukuoka Tokushukai Medical Center, Kasuga, Japan
Background/Purpose: Varus alignment is one factor of medial osteoarthritis (OA) of the knee. According to the concept of the constitutional varus, the bone growth disturbance…
Abstract Number: 2200 • 2017 ACR/ARHP Annual Meeting
History of Walking for Exercise Is Not Associated with More Symptomatic Knee Osteoarthritis: Data from the Osteoarthritis Initiative
Grace H. Lo¹, Jeffrey B. Driban², Andrea Kriska³, Timothy E. McAlindon⁴, Richard Souza⁵, Nancy J. Petersen⁶, Bonny Jane Rockette-Wagner⁷, Charles Eaton⁸, Marc Hochberg⁹, Rebecca D. Jackson¹⁰, C. Kent Kwoh¹¹, Michael C. Nevitt¹² and Maria Suarez-Almazor¹³, ¹Immunology, Allergy, Rheumatology, Baylor College of Medicine, Houston, TX, ²Rheumatology, Tufts Medical Center, Boston, MA, ³University of Pittsburgh, Pittsburgh, PA, ⁴Division of Rheumatology, Tufts Medical Center, Boston, MA, ⁵University of California, San Francisco, San Francisco, CA, ⁶Medicine, Baylor College of Medicine, Houston, TX, ⁷University of Pittsburgh Medical Center, Pittsburgh, PA, ⁸Family Medicine and Epidemiology, Warren Alpert Medical School, School of Public Health, Brown University, Providence, RI, ⁹Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, ¹⁰Ohio State University, Columbus, OH, ¹¹University of Arizona, Tucson, AZ, ¹²Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, ¹³Section of Rheumatology and Clinical Immunology, Department of General Internal Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA, Houston, TX
Background/Purpose: Walking is recommended for those with knee OA (KOA). However, few studies have explored the association between walking and symptomatic OA, and conflicting data…
Abstract Number: 317 • 2016 ACR/ARHP Annual Meeting
Leg Muscle Imbalance Is Associated with Radiographic Grade or Pain in Knee Osteoarthritis
Ji Yeon Lee¹, Kyungdo Han², Yong Gyu Park² and Sung-Hwan Park³, ¹International Healthcare Center, Seoul St Mary's Hosiptal, Seoul, Korea, Republic of, ²Department of Biostatistics, Catholic University of Korea, Seoul, South Korea, Seoul, Korea, The Republic of, ³Division of Rheumatology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, South Korea
Background/Purpose: Osteoarthritis(OA) has been recognized as a progressive disease resulting from stress in synovial joint tissues including periarticular muscles. In knee OA, quadriceps muscle mass…
Abstract Number: 1296 • 2016 ACR/ARHP Annual Meeting
Quantitative Measurements of Cartilage, Osteophyte, and Bone Marrow Lesion Volume in Knee Osteoarthritis
Lena Franziska Schaefer¹, Ming Yin¹, Meera Sury², Scott Jamieson¹, Jamie E. Collins³, Stacy Smith⁴ and Jeffrey Duryea¹, ¹Radiology, Brigham & Women's Hospital/ Harvard Medical School, Boston, MA, ²Brigham & Women's Hospital/ Harvard Medical School, Boston, MA, ³Orthopaedic and Arthritis Center for Outcomes Research, Department of Orthopedic Surgery, Brigham & Women's Hospital, Boston, MA, ⁴Radiology/Division of Musculoskeletal Imaging & Intervention, Brigham & Women's Hospital/ Harvard Medical School, Boston, MA
Quantitative Measurements of Cartilage, Osteophyte, and Bone Marrow Lesion volume in Knee Osteoarthritis Schaefer L.F., Yin M., Sury, M., Jamieson S., Collins J., Smith S.,…
Abstract Number: 2028 • 2016 ACR/ARHP Annual Meeting
Relationship of Limb Length Inequality and Incident and Progressive Knee and Hip Radiographic Osteoarthritis and Symptoms
Yvonne M. Golightly¹, Carolina Alvarez², Kelli Allen³, Jordan B. Renner⁴ and Joanne M. Jordan⁵, ¹Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, ²Thurston Arthritis Research Center, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, ³University of North Carolina at Chapel Hill and Durham VA Medical Center, Chapel Hill, NC, ⁴Radiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, ⁵Thurston Arthritis Research Center, University of North Carolina at Chapel Hill, Chapel Hill, NC
Background/Purpose: Limb length inequality (LLI) is a condition in which one limb is longer than the other. Previous reports of a link between LLI and…
Abstract Number: 296 • 2016 ACR/ARHP Annual Meeting
Knee Osteoarthritis As Risk for Hip Osteoarthritis
Chan Kim¹, Shanshan Sheehy², Cara Lewis³, Mary M Clancy^4,5,6, Michael C. Nevitt⁷, James Torner⁸, Cora E. Lewis⁹, Ali Guermazi¹⁰ and David T. Felson¹¹, ¹Rheumatology and Clinical Epidemiology, Boston University School of Medicine, Boston, MA, ²Clinical Epidemiology Research & Training Unit, Boston University, Boston, MA, ³Physical Therapy and Athletic Training, Boston University, Boston, MA, ⁴Clinical Epidemiology, BUSM, Boston, MA, ⁵Clinical Epidemiology, Boston University School Medical, Boston, MA, ⁶Clinical Epidemiology, Boston University Sch Med, Boston, MA, ⁷Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, ⁸University of Iowa, UIowa, Iowa City, IA, ⁹University of Alabama Birmingham, Birmingham, AL, ¹⁰Boston University School of Medicine, Boston, MA, ¹¹Clinical Epidemiology Unit, Boston University School of Medicine, Boston, MA
Knee osteoarthritis as risk factor for hip osteoarthritis Background/Purpose: While the hip and knee are linked biomechanically, the risk of hip osteoarthritis (OA) in persons…
Abstract Number: 2543 • 2015 ACR/ARHP Annual Meeting
Content Validity of the Improved Health Assessment Questionnaire in Knee Osteoarthritis Patients
Mei Chung¹, Shanshan Liu², Zhuxuan Fu², Lori Lyn Price³, John B. Wong⁴ and Chenchen Wang⁵, ¹Department of Public Health and Community Medicine, Tufts University School of Medicine, Boston, MA, ²Public Health and Community Medicine, Tufts University School of Medicine, Boston, MA, ³Clinical Care Research, Tufts Medical Center, Boston, MA, ⁴Medicine/Clinical Decision Making, Tufts Medical Center, Boston, MA, ⁵Rheumatology, Tufts Medical Center, Bosotn, MA
Background/Purpose: Developed in general population, rheumatoid arthritis and osteoarthritis patients, the Improved Health Assessment Questionnaire (iHAQ, formerly PROMIS HAQ) assesses physical function. The objective of…
Abstract Number: 2391 • 2015 ACR/ARHP Annual Meeting
Hip Osteoarthritis As the Cause for Knee Osteoarthritis in the Multicenter Osteoarthritis Study
Chan Kim^1,2, Jingbo Niu³, Cara Lewis⁴, Mary Clancy⁵, David T. Felson³ and Ali Guermazi⁶, ¹Internal Medicine and Rheumatology, Boston Medical Center, Boston, MA, ²Rheumatology, Boston University, Boston, MA, ³Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MA, ⁴Physical Therapy and Athletic Training, Boston University, Boston, MA, ⁵Clinical Epidemiology, BUSM, Boston, MA, ⁶Boston University School of Medicine, Boston, MA
Hip Osteoarthritis as the cause for Knee Osteoarthritis in the Multicenter Osteoarthritis Study Background/Purpose: While the hip and knee are linked biomechanically, there have been…
Abstract Number: 2273 • 2015 ACR/ARHP Annual Meeting
The Effect of Widespread Pain on Incident Knee Pain and Knee Osteoarthritis: The Multicenter Osteoarthritis (MOST) Study
Lisa Carlesso^1,2, Neil Segal³, Jeffrey R. Curtis⁴, Barton L. Wise⁵, Laura Frey-Law⁶, Michael C. Nevitt⁷, Anyu Hu⁸ and Tuhina Neogi⁹, ¹Division of Health Care & Outcomes Research, Toronto Western Research Institute, University Health Network, Toronto, ON, Canada, ²School of Rehabiliation, Maisonneuve Rosemont Research Institute, Université de Montréal, Montreal, QC, Canada, ³University of Kansas, Shawnee, KS, ⁴Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL, ⁵Int Medicine, UCDMC, Sacramento, CA, ⁶UIowa, Iowa City, IA, ⁷Epidemiology and Biostatistics, UCSF, San Francisco, CA, ⁸Clinical Epidemiology Research Unit, Boston University School of Medicine, Boston, MA, ⁹Clinical Epidemiology, BUSM, Boston, MA
Background/Purpose: Widespread pain (WSP) may be present in individuals for numerous reasons, and its presence may affect the degree to which people engage in activities.…