ACR Meeting Abstracts

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Abstracts tagged "Juvenile idiopathic arthritis (JIA) and uveitis"

  • Abstract Number: 2726 • 2019 ACR/ARP Annual Meeting

    Baseline Characteristics and Quality of Life Metrics in Non-Infectious Uveitis

    Jessica Shantha1, Amy Cassedy 2, Joseph McDonald 3, Theresa Hennard 4, Najima Mwase 5, Steven Yeh 1 and Sheila Angeles-Han 6, 1Emory University, Atlanta, GA, 2Division of Biostatistics and Epidemiology, Cincinnati Children's Hospital Medical Center, Cincinnati, 3Division of Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, 4Division of Rheumatology, Cincinnati Children's Hospital and Medical Center, Cincinnati, OH, 5Division of Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 6Division of Rheumatology, Cincinnati Children's Hospital Medical Center, Cinicinnati

    Background/Purpose: Uveitis is a heterogenous group of ocular inflammatory diseases. Underlying disease and treatment can lead to poor quality of life (QOL), depression, and increased…
  • Abstract Number: 2408 • 2018 ACR/ARHP Annual Meeting

    Comparison of the Tear Cytokine and Chemokine Profile of Children with JIA and JIA-Associated Uveitis

    Sheila Angeles-Han1, Virginia Miraldi Utz2, Sherry Thornton3, Alyssa Sproles3, Najima Mwase4, Theresa Hennard3, Mekibib Altaye4 and Gary Holland5, 1Rheumatology, Cincinnati Children's Hospital Medical Center and University of Cincinnati, Cincinnati, OH, 2Pediatric Ophthalmology, Cincinnati Children's Hospital Medical Center and University of Cincinnati, Cincinnati, OH, 3Division of Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 4Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 5Jules Stein Eye Institute, Jules Stein Eye Institute, University of California, Los Angeles, Los Angeles, CA

    Background/Purpose: Children with JIA are at increased risk for uveitis. Known risk factors do not accurately stratify risk. Biomarkers are needed to predict uveitis development…
  • Abstract Number: 977 • 2018 ACR/ARHP Annual Meeting

    Nurse Led Safe Switching from Original Reference Product Infliximab to Biosimalar in Patients with Juvenile Idiopathic Arthritis and Uveitis – a Single Centre Experience Including Baseline and Post Switch Infliximab Levels and Antibodies

    Andrew Fell1, Emma Carson1, Gillian Coyle1, Neil Martin1, Jo Walsh1 and Janet Gardner-Medwin2, 1Paediatic Rheumatology, Royal hospital for Children, Glasgow, United Kingdom, 2School of Medicine, Dentistry & Nursing, Child Health, University of Glasgow, Glasgow, United Kingdom

    Background/Purpose: Original Reference Product (ORP) Infliximab lost market exclusivity in europe in early 2015. The Scottish National Health service (SNHS), runs a national procurement system…
  • Abstract Number: 2299 • 2017 ACR/ARHP Annual Meeting

    Clinical Features and Characteristics of Juvenile Idiopathic Arthritis-Associated Uveitis in Japan:the First Report from the Pediatric Rheumatology Association of Japan (PRAJ)

    Junko Yasumura1, Masato Yashiro2, Nami Okamoto3, Kosuke Shabana4, Hiroaki Umebayashi5, Naomi Iwata6, Tomohiro Kubota7, Mao Mizuta8, Kenichi Nishimura9, Yuka Okura10, Masaki Shimizu8, Minako Tomiita11, Syuji Takei7 and Masaaki Mori12, 1Department of Pediatrics, Hiroshima University Graduate School of Biomedical & Health Sciences, Hiroshima, Japan, 2Department of Pediatrics, Okayama University Hospital, Okayama, Japan, 3Pediatrics, Graduate School of Medicine, Osaka Medical College, Takatsuki, Japan, 4Department of Pediatrics, Graduate School of Medicine, Osaka Medical College, Takatsuki, Japan, 5Department of Rheumatics, Miyagi Children’s Hospital, Sendai, Japan, 6Department of Immunology and Infectious Diseases, Aichi Children’s Health and Medical Center, Obu, Japan, 7Department of Pediatrics, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan, 8Department of Pediatrics, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Japan, 9Department of Pediatrics, Yokohama City University Graduate School of Medicine, Yokohama, Japan, 10Department of Pediatrics, KKR Sapporo Medical Center, Sapporo, Japan, 11Department of Allergy and Rheumatology, Chiba Children's Hospital, Chiba, Japan, 12Department of Lifetime Clinical Immunology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan

    Background/Purpose: Several reports examined ethnic differences of Juvenile Idiopathic Arthritis -associated uveitis (JIA-U), however, there were no information from Japan. Therefore, PRAJ underwent multi-center surveillance…
  • Abstract Number: 2318 • 2017 ACR/ARHP Annual Meeting

    Measurement of Serum Infliximab and Antibody Levels As an Adjunct to Clinical Decision Making Regarding Infliximab Therapy

    Eileen Pagano1, Myriam Kline2 and B. Anne Eberhard3, 1Pediatric Rheumatology, Cohen Children's Medical Center of New York, New Hyde Park, NY, 2Biostatistics Unit, Feinstein Institute for Medical Research, Northwell Health, Manhasset, NY, 3Pediatric Rheumatology, Cohen Children's Medical Center of New York, Lake Success, NY

    Background/Purpose: Infliximab (IFX) is a chimeric monoclonal antibody against tumor necrosis factor alpha (TNF-a). It is known to be effective and often used in the…
  • Abstract Number: 2323 • 2017 ACR/ARHP Annual Meeting

    Exploring HLA-DRB1 Risk Alleles in Non-Hispanic African American Children with Juvenile Idiopathic Arthritis and Chronic Anterior Uveitis

    Lai Hin Kimi Chan1, Courtney McCracken1, Kirsten Jenkins2, Steven Yeh3, Purnima Patel4, Sampath Prahalad5 and Sheila Angeles-Han6, 1Pediatrics, Emory University School of Medicine, Atlanta, GA, 2Children's Healthcare of Atlanta, Atlanta, GA, 3Ophthalmology, Emory University School of Medicine, Atlanta, GA, 4Emory University School of Medicine, Atlanta, GA, 5Pediatrics, Emory Children's Center, Atlanta, GA, 6Department of Pediatrics, Cincinnati Children's Hospital, Cincinnati, OH

    Exploring HLA-DRB1 Risk Alleles in Non-Hispanic African American Children with Juvenile Idiopathic Arthritis and Chronic Anterior UveitisBackground/Purpose: HLA-DRB1*08, 11 and 13 are risk alleles associated…
  • Abstract Number: 68 • 2017 Pediatric Rheumatology Symposium

    HLA-DRB1 in Non-Hispanic African American Children with Juvenile Idiopathic Arthritis and Chronic Anterior Uveitis

    Lai Hin Kimi Chan1, Courtney McCracken1, Kirsten Jenkins2, Steven Yeh3, Purnima Patel4, Sampath Prahalad1 and Sheila Angeles-Han5, 1Pediatrics, Emory University School of Medicine, Atlanta, GA, 2Children's Healthcare of Atlanta, Atlanta, GA, 3Ophthalmology, Emory University School of Medicine, Atlanta, GA, 4Emory University School of Medicine, Atlanta, GA, 5Department of Pediatrics, Cincinnati Children's Hospital, Cincinnati, OH

    Background/Purpose: HLA-DRB1*08, 11 and 13 are strong risk alleles for various juvenile idiopathic arthritis (JIA) subtypes. We reported that carriage of DRB1*11 and *13 increased…
  • Abstract Number: 2427 • 2016 ACR/ARHP Annual Meeting

    Identification of Biomarkers Using Tear Proteomics in Children with Chronic Anterior Uveitis

    Sheila Angeles-Han1,2, Duc Duong3, Steven Yeh4, Purnima Patel1, Kirsten Jenkins2, Sampath Prahalad2,5 and Gary Holland6, 1Emory University School of Medicine, Atlanta, GA, 2Children's Healthcare of Atlanta, Atlanta, GA, 3Emory University, Atlanta, GA, 4Ophthalmology, Emory University School of Medicine, Atlanta, GA, 5Pediatric Rheumatology, Emory University School of Medicine, Atlanta, GA, 6Jules Stein Eye Institute, Jules Stein Eye Institute, University of California, Los Angeles, Los Angeles, CA

    Background/Purpose: Children with juvenile idiopathic arthritis (JIA) are at risk for anterior uveitis which can lead to ocular complications and vision loss.  The ANA is…
  • Abstract Number: 2901 • 2014 ACR/ARHP Annual Meeting

    Predictors of Relapse after Discontinuing Systemic Treatment in Childhood Autoimmune Chronic Uveitis

    Gabriele Simonini1, Claudia Bracaglia2, Marco Cattalini3, Andrea Taddio4, Alice Brambilla5, Cinzia DeLibero6, Denise Pires Marafon7, Roberto Caputo6 and Rolando Cimaz1, 1Pediatric Rheumatology, Anna Meyer Children's Hospital-University of Firenze, Florence, Italy, 2Department of Pediatric Medicine, Division of Rheumatology, Ospedale Pediatrico Bambino Gesù, IRCCS, Rome, Italy, 3Pediatric Clinic, Spedali Civili di Brescia and University of Brescia, Pediatric Immunology and Rheumatology Unit, Brescia, Italy, 4Institute of Child Health, IRCCS Burlo Garofolo, University of Trieste, Trieste, Italy, 5Anna Meyer Children's Hospital-University of Firenze, Florence, Italy, 6Ophthalmology Unit, Anna Meyer Children's Hospital, Florence, Italy, 7Ospedale Pediatrico Bambino Gesù, IRCCS, Roma, Italy

    Background/Purpose Information regarding the natural clinical history of a child on systemic treatment due to auto-immune chronic uveitis would be helpful in driving duration therapy.…
  • Abstract Number: 295 • 2013 ACR/ARHP Annual Meeting

    Uveitis In The Nordic Juvenile Idiopathic Arthritis Cohort; High Incidence, Frequent Complications, and Gender Associated Risk Factors

    Ellen Nordal1,2, Lillemor Berntson3, Kristiina Aalto4, Suvi Peltoniemi5, Susan Nielsen6, Troels Herlin7, Anders Fasth8 and Marite Rygg9,10, 1Department of Pediatrics, University Hospital of North Norway, Tromsø, Norway, 2Department of Clinical Medicine, University of Tromsø, Tromsø, Norway, 3Department of Pediatrics, Uppsala University Hospital, Uppsala, Sweden, 4Department of Pediatrics,, Helsinki University Children's Hospital, Helsinki, Finland, 5Department of Pediatrics, Helsinki University Children's Hospital, Helsinki, Finland, 6Pediatric Rheumatology Unit, Juliane Marie Centret, Rigshospitalet, Copenhagen, Denmark, 7Pediatric Rheumatology Clinic, Department of Pediatrics, Aarhus University Hospital, Aarhus, Denmark, 8Department of Pediatrics, University of Gothenburg, Gothenburg, Sweden, 9Department of Laboratory Medicine, Children's and Women's health, Norwegian University of Science and Technology, Trondheim, Norway, 10Department of Pediatrics, St Olav University Hospital, Trondheim, Norway

    Background/Purpose: Uveitis is the most common extra-articular manifestation of juvenile idiopathic arthritis (JIA). Both incidence and reported outcome varies, and population-based data are scarce. Early…
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