Abstracts tagged "Juvenile Arthritis"

Abstract Number: 157 • 2020 Pediatric Rheumatology Symposium
Chondrocytes Influence Fibroblast-like Synoviocytes from Patients with Juvenile Idiopathic Arthritis, Through the Abrogation of BMP Signaling, to Delay Cell Differentiation and Maturation
Megan Simonds ¹, Amanda Schlefman ², Kathleen Sullivan ³, Carlos Rose ⁴ and AnneMarie Brescia⁵, ¹Nemours Biomedical Research, Wilmington, ²Johns Hopkins Rheumatology, ST PETERSBURG, Florida, ³The Children's Hospital of Philadelphia, Philadelphia, ⁴Thomas Jefferson University/duPont Hospital for Children, Wilmington, ⁵Nemours/ Alfred I duPont Hospital for Children, Wilmington
Background/Purpose: Juvenile Idiopathic Arthritis (JIA) progression leads to growth disturbances in affected joints. Fibroblast-like synoviocytes (FLS) play a key role in JIA pathogenesis; however, the…
Abstract Number: 1812 • 2019 ACR/ARP Annual Meeting
Delineating Early Response Trajectories to Biologics in Polyarticular Course Juvenile Idiopathic Arthritis
Lily SH Lim¹, Armend Lokku ², Sarah Ringold ³ and Eleanor M. Pullenayegum ⁴, ¹University of Manitoba, Winnipeg, MB, Canada, ²University of Toronto, TOronto, ON, Canada, ³Seattle Children's, Seattle, ⁴Child Health Evaluative Sciences, The Hospital for Sick Children, Dalla Lana School of Public Health, University of Toronto, Toronto, Canada
Background/Purpose: Most biologic trials in juvenile idiopathic arthritis (JIA) treat all participants with the biologic under study for 12 to 16 weeks before randomizing responders…
Abstract Number: 1951 • 2019 ACR/ARP Annual Meeting
Transcriptomic Responses in CD4+ T Cells During Successful Therapy for Juvenile Idiopathic Arthritis
Tarbell Evan ¹, Kaiyu Jiang ¹, Tao Liu ² and James N. Jarvis³, ¹University at Buffalo Jacobs School of Medicine, Buffalo, NY, ²Roswell Park Cancer Instiyute, Buffalo, NY, ³University at Buffalo, Jacobs School of Medicine and Biomedical Sciences, Buffalo, NY
Background/Purpose: We have shown that therapeutic response in juvenile idiopathic arthritis (JIA) is a non-linear process invloving reorganization of gene expression networks. However, our earlier…
Abstract Number: 2723 • 2019 ACR/ARP Annual Meeting
Alagille Syndrome and Chronic Arthritis: An International Case Series
Giovanna Ferrara ¹, Teresa Giani¹, Scott M Lieberman ², Sandy Hong ³, Courtney Kremer ³, Giuseppe Indolfi ¹, Grant Schulert ⁴, Randy Cron ⁵, Melissa Mannion ⁶, Sivia Lapidus ⁷, Emmanuel Jacquemin ⁸, Isabelle Kone-Paut ⁹ and Rolando Cimaz ¹⁰, ¹Anna Meyer Children University Hospital, Florence, Italy, ²University of Iowa, Iowa City, Iowa City, ³University of Iowa, Iowa City, Iowa City, IA, ⁴Division of Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ⁵University of Alabama at Birmingham, Birmingham, AL, ⁶University of Alabama at Birmingham, Alabama, ⁷Joseph M. Sanzari Children’s Hospital, Hackensack Meridian Health, New Jersey, ⁸Le Kremlin Bicetre, Paris, France, ⁹Rhumatologie pédiatrique et CEREMAIA,, Université Paris-Sud Saclay, Paris, France, ¹⁰Meyer Children's Hospital in Florence, Florence, Italy
Background/Purpose: Alagille syndrome is a complex multisystem disease characterized by chronic cholestasis due to a paucity of intrahepatic bile ducts, congenital heart disease and ocular…
Abstract Number: PP05 • 2018 ACR/ARHP Annual Meeting
Integrative Approach to Treatment of an Adult with Juvenile Rheumatoid Arthritis
Shannan O'Hara-Levi, Patient, Staten Island, NY
Background/Diagnosis: I was diagnosed in 1987 at age 3 with Polyarticular Juvenile Rheumatoid Arthritis which effected every joint in my body. At time of diagnosis…
Abstract Number: 1427 • 2018 ACR/ARHP Annual Meeting
A New Model of Care for Pediatric Rheumatology in Ontario: Preliminary Results from Pilot Telemedicine Clinics Utilizing Advanced Clinician Practitioners in Arthritis Care
Roberta Berard¹, Susan MacQueen², Michelle Diebold³, Y. Ingrid Goh⁴, Anne MacLeod⁵, Kristi Whitney-Mahoney⁶, Christine O'Brien⁶, Brian M. Feldman⁷ and Deborah M. Levy⁸, ¹Pediatrics, Children's Hospital, London Health Sciences Centre, London, ON, Canada, ²The Arthritis Society, Kitchener, ON, Canada, ³Department of Rheumatology, Children's Hospital, London Health Sciences Centre, London, ON, Canada, ⁴Child Health Evaluative Sciences, The Hospital for Sick Children, Toronto, ON, Canada, ⁵The Arthritis Society, Thunder Bay, ON, Canada, ⁶The Hospital for Sick Children, Toronto, ON, Canada, ⁷Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada, ⁸Division of Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada
AbstractBackground/Purpose: Twenty-five pediatric rheumatologists (PR) service a population of 14 million Ontarians. To facilitate care to patients living in distance communities we proposed a new…
Abstract Number: 2401 • 2018 ACR/ARHP Annual Meeting
The Effects of a Gluten-Free Diet in Juvenile Idiopathic Arthritis – a Pilot Study
Anjali Sura¹, Stacey Fogarty-Brown² and Meredith Riebschleger³, ¹Pediatric Rheumatology, University of Michigan, Ann Arbor, MI, ²Pediatrics, University of Michigan, Ann Arbor, MI, ³Pediatric Rheumatology & Health Services Research, University of Michigan, Ann Arbor, MI
Background/Purpose: The caregivers of children with juvenile idiopathic arthritis (JIA) frequently ask about the utility of dietary restrictions. Some patients and physicians report a good…
Abstract Number: 2402 • 2018 ACR/ARHP Annual Meeting
Acoustic Emissions Generated By the Temporomandibular Joint of Patients with Juvenile Idiopathic Arthritis and Their Implication on Patient Assessment and Screening: A Pilot Study
Daniel Whittingslow^1,2, Hyeon Ki Jeong³, Talia Gergely⁴, Lori Ponder⁴, Sampath Prahalad⁵, Omer Inan³ and Shelly Abramowicz⁶, ¹Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, ²Emory University School of Medicine, Atlanta, GA, ³Electrical and Computer Engineering, Georgia Institute of Technology, Atlanta, GA, ⁴Emory University, Atlanta, GA, ⁵Pediatrics, Emory University, Atlanta, GA, ⁶Surgery, Emory University/Children's Healthcare of Atlanta, Atlanta, GA
Background/Purpose: The temperomandibular joint (TMJ) is one of the most commonly affected joints in juvenile idiopathic arthritis (JIA) (up to 45% of cases). There is a discrepancy between…
Abstract Number: 2306 • 2017 ACR/ARHP Annual Meeting
Demographic and Clinical Characteristics of Hispanic Children with Juvenile Idiopathic Arthritis: An International, Multicenter Cross-Sectional Study
Martha Rodriguez¹, Melissa Tesher¹, Deirdre De Ranieri¹, Linda Wagner-Weiner², Tamar Rubinstein³, Janet Orrock⁴, Christine Arango⁵, Angela Mosquera⁵, Carmen Tineo⁶, Romilda Salas⁷, Esthela Loyo⁸, Karen Onel⁹ and Maria Alkureishi¹⁰, ¹Pediatric Rheumatology, The University of Chicago Medicine, Chicago, IL, ²The University of Chicago Medicine, Chicago, IL, ³Albert Einstein College of Medicine, Children's Hospital at Montefiore, New York, NY, ⁴Pediatric Rheumatology, Albert Einstein College of Medicine, Children's Hospital at Montefiore, NY, Albania, ⁵Pediatric Rheumatology, Pediatric rheumatology post graduate program El Bosque University, Bogota, Colombia, ⁶Division of Rheumatology, Hospital Regional Universitario José Ma Cabral Baez, Santiego, Dominican Republic, ⁷Rheumatology, Hospital Regional Universitario José Ma Cabral Baez, Santiago, Dominican Republic, ⁸Departamento de Reumatologia, Hospital Regional Universitario José Ma Cabral Baez, Santiago, Dominican Republic, ⁹Division of Pediatric Rheumatology, University of Chicago, Chicago, IL, ¹⁰Pediatrics, The University of Chicago Medicine, Chicago, IL
Background/Purpose: Higher disease activity has been described in Hispanic patients with Juvenile Idiopathic Arthritis (JIA) living in the United States (US) vs non-Hispanics. There is…
Abstract Number: 2310 • 2017 ACR/ARHP Annual Meeting
Increased Risk of Extreme Obesity in Adults with History of Childhood Arthritis
Sangeeta Sule¹ and Kevin Fontaine², ¹Pediatrics, Johns Hopkins University, Baltimore, MD, ²Dept. of Health Behavior, Univ. of Alabama at Birmingham, Birmingham, AL
Background/Purpose: Over one-third of U.S. adults are obese, leading to major health conditions and increased costs. Identified risk factors that contribute to obesity include lifestyle,…
Abstract Number: 2317 • 2017 ACR/ARHP Annual Meeting
Knowledge Translation in Juvenile Idiopathic Arthritis in Canada: A Focus on Parents of Children with JIA
Julia Wright¹, Benjamin Rose-Davis², Michelle Batthish³, Tania Cellucci⁴, Ciarán M. Duffy⁵, Lori Tucker⁶, Adam Huber⁷, Bianca Lang⁸, Deborah M. Levy⁹, Dax Rumsey¹⁰, Karen N Watanabe Duffy¹¹, Janet Curran¹² and Elizabeth Stringer¹³, ¹Faculty of Medicine, Dalhousie University, Halifax, NS, Canada, ²Department of Computer Science, Health Informatics, Dalhousie University, Halifax, NS, Canada, ³Division of Pediatric Rheumatology, McMaster Children's Hospital, Hamilton, ON, Canada, ⁴McMaster University, hamilton, ON, Canada, ⁵Children's Hospital of Eastern Ontario and University of Ottawa, Ottawa, ON, Canada, ⁶BC Children's Hospital, Vancouver, BC, Canada, ⁷IWK Health Centre, Halifax, NS, Canada, ⁸Pediatrics, IWK Health Centre, Halifax, NS, Canada, ⁹Division of Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada, ¹⁰Stollery Children's Hospital, Edmonton, AB, Canada, ¹¹Rheumatology, Children's Hospital of Eastern Ontario and University of Ottawa, Ottawa, ON, Canada, ¹²Department of Pediatrics, IWK Health Centre, Halifax, NS, Canada, ¹³Department of Rheumatology, IWK Health Centre, Halifax, NS, Canada
Background/Purpose: The Research in Canadian Children with Childhood Arthritis Emphasizing Outcomes (ReACCh-Out) cohort (2005-2010) has characterized outcomes for Canadian children with Juvenile Idiopathic Arthritis (JIA).…
Abstract Number: 2326 • 2017 ACR/ARHP Annual Meeting
Modeling Transcriptional Rewiring in Neutrophils through the Course of Treated Juvenile Idiopathic Arthritis
Zihua Hu¹, Kaiyu Jiang², Mark B. Frank³, Yanmin Chen² and James Jarvis⁴, ¹Center for Computational Research, University at Buffalo, Buffalo, NY, ²Pediatrics, University at Buffalo, Buffalo, NY, ³Arthritis and Clinical Immunology Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, ⁴Department of Genetics, Genomics & Bioinformatics, University at Buffalo, Buffalo, NY
Background/Purpose: We have previously shown that neutrophils in children with polyarticular juvenile idiopathic arthritis (JIA) display abnormal transcriptional patterns linked to fundamental metabolic derangements. These…
Abstract Number: 2328 • 2017 ACR/ARHP Annual Meeting
Characterisation of Lipid Mediator Profile and Immune Cells in Synovial Fluid of Juvenile Idiopathic Arthritis
Johannes Hendrick von Hegedus¹, Q. S. R. Madari², P.C.E. Hissink Muller³, M. Kloppenburg⁴, REM Toes⁴, Martin Giera⁵, TWJ Huizinga⁴, Rebecca ten Cate⁶ and A. Ioan-Facsinay⁴, ¹Department of Rheumatology, LUMC, Leiden, Netherlands, ²LUMC, Leiden, Netherlands, ³Willem-Alexander Children's Hospital, LUMC, Leiden, Netherlands, ⁴Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ⁵Center for Proteomics and Metabolomics, Leiden University Medical Center, Leiden, Netherlands, ⁶Leiden University Medical Center, Leiden, Netherlands
Background/Purpose: Juvenile Idiopathic Arthritis (JIA) is often accompanied by inflammation of the joints. The mechanisms involved in the inflammation in JIA are incompletely understood. Several…
Abstract Number: 2330 • 2017 ACR/ARHP Annual Meeting
Evidence for Alternatively Activated (M2) Macrophage Activation in Patients with Enthesitis Related Arthritis Category of Juvenile Idiopathic Arthritis
Amita Aggarwal¹, Priyanka Gaur² and Akhilesh Yadav³, ¹Clinical Immunology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India, ²Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India, ³Department of Clinical Immunology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
Background/Purpose: Among juvenile idiopathic arthritis (JIA), enthesitis related arthritis (ERA) category includes most children with juvenile onset spondyloarthropathy (SpA). Synovial fluid from patients with SpA…
Abstract Number: 339 • 2017 ACR/ARHP Annual Meeting
Patients’ Attitudes and Experiences of Transitional Care in Paediatric Rheumatology: A Systematic Review of Qualitative Studies
Ayano Kelly^1,2,3,4, Fiona Niddrie⁵, David Tunnicliffe^4,6, Camilla Hanson^4,7, Gabor Major^8,9, Davinder Singh-Grewal^10,11,12 and Allison Tong⁴, ¹Rheumatology, The Canberra Hospital, Canberra, Australia, ²School of Medicine, Australian National University, Canberra, Australia, ³Canberra Rheumatology, Canberra, Australia, ⁴Centre for Kidney Research, The Children's Hospital at Westmead, Sydney, Australia, ⁵Rheumatology, Bone and Joint Institute,John Hunter Hospital, Newcatle, Australia, ⁶Sydney School of Public Health, University of Sydney, Sydney, Australia, ⁷Sydney School of Pubic Health, University of Sydney, Sydney, Australia, ⁸Medicine, University of Newcastle, Newcastle, Australia, ⁹Rheumatology, Bone and Joint Institute, John Hunter Hospital NSW Australia, Newcastle, Australia, ¹⁰Faculty of Medicine, University of New South Wales, Sydney, Australia, ¹¹Department of Rheumatology, The Sydney Children's Hospital Network, Sydney, Australia, ¹²Sydney Medical School, University of Sydney, Sydney, Australia
Background/Purpose: Despite the increasing number of transition programs available for rheumatology patients moving from paediatric to adult care, transition continues to pose challenges for patients…

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